IT7969032A0 - Procedimento per la produzione del l ossimorfone - Google Patents

Procedimento per la produzione del l ossimorfone

Info

Publication number
IT7969032A0
IT7969032A0 IT7969032A IT6903279A IT7969032A0 IT 7969032 A0 IT7969032 A0 IT 7969032A0 IT 7969032 A IT7969032 A IT 7969032A IT 6903279 A IT6903279 A IT 6903279A IT 7969032 A0 IT7969032 A0 IT 7969032A0
Authority
IT
Italy
Prior art keywords
oxymorphone
procedure
production
Prior art date
Application number
IT7969032A
Other languages
English (en)
Inventor
Michael L Wilson
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of IT7969032A0 publication Critical patent/IT7969032A0/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polarising Elements (AREA)
IT7969032A 1978-10-19 1979-10-18 Procedimento per la produzione del l ossimorfone IT7969032A0 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95305678A 1978-10-19 1978-10-19

Publications (1)

Publication Number Publication Date
IT7969032A0 true IT7969032A0 (it) 1979-10-18

Family

ID=25493512

Family Applications (1)

Application Number Title Priority Date Filing Date
IT7969032A IT7969032A0 (it) 1978-10-19 1979-10-18 Procedimento per la produzione del l ossimorfone

Country Status (16)

Country Link
JP (1) JPS55501025A (it)
AU (1) AU5189779A (it)
BE (1) BE879494A (it)
CA (1) CA1108132A (it)
CS (1) CS211364B2 (it)
DK (1) DK258280A (it)
ES (1) ES485154A1 (it)
FI (1) FI793235A (it)
FR (1) FR2439201A1 (it)
GB (1) GB2049680A (it)
IL (1) IL58489A0 (it)
IT (1) IT7969032A0 (it)
NL (1) NL7920126A (it)
NO (1) NO793297L (it)
SE (1) SE8004454L (it)
WO (1) WO1980000841A1 (it)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795813A (en) * 1981-08-17 1989-01-03 The Florida Board Of Regents On Behalf Of The Florida State University Synthesis of derivatives of codeine and other 3-O-alkylmorphines
US5668285A (en) * 1986-10-31 1997-09-16 The United States Of America As Represented By The Department Of Health And Human Services Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
FR2636330B1 (fr) * 1988-09-13 1990-11-30 Sanofi Sa Procede de preparation de derives de morphinane
DE69033035T2 (de) * 1989-10-16 1999-08-05 The United States of America, represented by the Secretary, U.S. Department of Commerce, Washington, D.C. Totale synthese von northebain-, normorphin-, noroxymorphon-enantiomeren und -derivaten via n-nor-zwischenverbindungen
EP1414458B1 (en) 2001-07-06 2007-04-11 Endo Pharmaceuticals Inc. Oral administration of 6-hydroxy-oxymorphone for use as an analgesic
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
CN101395159A (zh) 2006-03-02 2009-03-25 马林克罗特公司 制备含有低含量α,β-不饱和酮化合物的吗啡烷-6-酮产物的方法
CN102014877B (zh) 2008-01-25 2017-06-06 格吕伦塔尔有限公司 药物剂型
DK2273983T3 (en) 2008-05-09 2016-09-19 Gruenenthal Gmbh A process for the preparation of a powdery formulation intermediate and a fixed final dosage form using a sprøjtestørkningstrin
MX2012000317A (es) 2009-07-22 2012-02-08 Gruenenthal Gmbh Forma de dosificacion de liberacion controlada extruida por fusion en caliente.
US20110020451A1 (en) 2009-07-22 2011-01-27 Grunenthal Gmbh Tamper-resistant dosage form for oxidation-sensitive opioids
MX2013002377A (es) 2010-09-02 2013-04-29 Gruenenthal Gmbh Forma de dosificacion resistente a manipulacion que comprende una sal inorganica.
BR112013005234A2 (pt) 2010-09-02 2016-05-03 Gruenenthal Gmbh forma de dosagem resistente à violação compreendendo um polímero aniônico.
EP2736497B1 (en) 2011-07-29 2017-08-23 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
DK2736495T3 (da) 2011-07-29 2017-11-13 Gruenenthal Gmbh Misbrugsbestandig tablet som tilvejebringer øjeblikkelig frigivelse af lægemiddel
CA2864949A1 (en) 2012-02-28 2013-09-06 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
CA2868142A1 (en) 2012-04-18 2013-10-24 Grunenthal Gmbh Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
AR096438A1 (es) 2013-05-29 2015-12-30 Gruenenthal Gmbh Forma de dosificación resistente al uso indebido con perfil de liberación bimodal, proceso
EP3003279A1 (en) 2013-05-29 2016-04-13 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
KR20160031526A (ko) 2013-07-12 2016-03-22 그뤼넨탈 게엠베하 에틸렌-비닐 아세테이트 중합체를 함유하는 템퍼 내성 투여형
AU2014356581C1 (en) 2013-11-26 2020-05-28 Grunenthal Gmbh Preparation of a powdery pharmaceutical composition by means of cryo-milling
CA2947786A1 (en) 2014-05-12 2015-11-19 Grunenthal Gmbh Tamper resistant immediate release capsule formulation comprising tapentadol
JP2017516789A (ja) 2014-05-26 2017-06-22 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エタノール過量放出に対して防護されている多粒子
CN107889459A (zh) 2015-04-24 2018-04-06 格吕伦塔尔有限公司 具有立即释放和对溶剂萃取的抗性的抗篡改剂型
WO2017042325A1 (en) 2015-09-10 2017-03-16 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
ES2701855T3 (es) 2016-05-31 2019-02-26 Alcaliber Investig Desarrollo E Innovacion Slu Proceso para la obtención de 3,14-diacetiloximorfona a partir de oripavina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3249616A (en) * 1966-05-03 Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof
US2806033A (en) * 1955-08-03 1957-09-10 Lewenstein Morphine derivative
US3775414A (en) * 1972-05-10 1973-11-27 Bristol Myers Co Process for the preparation of 14-hydroxymorphinan derivatives

Also Published As

Publication number Publication date
FR2439201A1 (fr) 1980-05-16
JPS55501025A (it) 1980-11-27
NL7920126A (nl) 1980-08-29
DK258280A (da) 1980-06-17
CA1108132A (en) 1981-09-01
WO1980000841A1 (en) 1980-05-01
AU5189779A (en) 1980-04-24
IL58489A0 (en) 1980-01-31
CS211364B2 (en) 1982-02-26
SE8004454L (sv) 1980-06-16
ES485154A1 (es) 1980-06-16
BE879494A (fr) 1980-02-15
FI793235A (fi) 1980-04-20
GB2049680A (en) 1980-12-31
NO793297L (no) 1980-04-22

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