IL46883A - 4-(alkoxy and/or hydroxyphenyl)-pyrrolid-2-one or 2-thione derivatives, their preparation and pharmaceutical composiions containing the same - Google Patents

4-(alkoxy and/or hydroxyphenyl)-pyrrolid-2-one or 2-thione derivatives, their preparation and pharmaceutical composiions containing the same

Info

Publication number
IL46883A
IL46883A IL46883A IL4688375A IL46883A IL 46883 A IL46883 A IL 46883A IL 46883 A IL46883 A IL 46883A IL 4688375 A IL4688375 A IL 4688375A IL 46883 A IL46883 A IL 46883A
Authority
IL
Israel
Prior art keywords
composiions
pyrrolid
hydroxyphenyl
alkoxy
pharmaceutical
Prior art date
Application number
IL46883A
Other languages
English (en)
Other versions
IL46883A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL46883A0 publication Critical patent/IL46883A0/xx
Priority to IL50451A priority Critical patent/IL50451A/xx
Publication of IL46883A publication Critical patent/IL46883A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL46883A 1974-03-20 1975-03-20 4-(alkoxy and/or hydroxyphenyl)-pyrrolid-2-one or 2-thione derivatives, their preparation and pharmaceutical composiions containing the same IL46883A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL50451A IL50451A (en) 1975-03-20 1976-09-10 4-(3,4-dimethoxyphenyl)-2-pyrrolidone-1-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2413935A DE2413935A1 (de) 1974-03-20 1974-03-20 4-(polyalkoxy-phenyl)-2-pyrrolidone

Publications (2)

Publication Number Publication Date
IL46883A0 IL46883A0 (en) 1975-05-22
IL46883A true IL46883A (en) 1979-09-30

Family

ID=5910915

Family Applications (1)

Application Number Title Priority Date Filing Date
IL46883A IL46883A (en) 1974-03-20 1975-03-20 4-(alkoxy and/or hydroxyphenyl)-pyrrolid-2-one or 2-thione derivatives, their preparation and pharmaceutical composiions containing the same

Country Status (20)

Country Link
US (1) US4012495A (enExample)
JP (1) JPS6011028B2 (enExample)
AT (1) AT347931B (enExample)
BE (1) BE826923A (enExample)
CA (1) CA1069517A (enExample)
CH (1) CH621338A5 (enExample)
CS (1) CS214738B2 (enExample)
DD (1) DD119229A5 (enExample)
DE (1) DE2413935A1 (enExample)
DK (1) DK139965C (enExample)
ES (1) ES435750A1 (enExample)
FR (1) FR2264531B1 (enExample)
GB (1) GB1498705A (enExample)
HU (1) HU174074B (enExample)
IE (1) IE40865B1 (enExample)
IL (1) IL46883A (enExample)
NL (1) NL7503367A (enExample)
SE (1) SE402010B (enExample)
SU (1) SU649312A3 (enExample)
YU (1) YU40258B (enExample)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
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KR20160042039A (ko) 2013-08-09 2016-04-18 알데릭스, 인코포레이티드 인산염 수송을 억제하기 위한 화합물 및 방법
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport

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FR1516776A (fr) 1966-07-21 1968-03-15 Rhone Poulenc Sa Nouveaux dérivés du pyrrole et leur préparation
GB1350582A (en) * 1970-07-24 1974-04-18 Ucb Sa Cerivatives of 2-pyrrolidinone

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IL46883A0 (en) 1975-05-22
DE2413935C2 (enExample) 1988-05-26
JPS6011028B2 (ja) 1985-03-22
DK139965B (da) 1979-05-28
JPS50157360A (enExample) 1975-12-19
SU649312A3 (ru) 1979-02-25
FR2264531B1 (enExample) 1978-07-28
IE40865B1 (en) 1979-08-29
ATA210975A (de) 1978-06-15
GB1498705A (en) 1978-01-25
CS214738B2 (en) 1982-05-28
AT347931B (de) 1979-01-25
DK110675A (enExample) 1975-09-21
BE826923A (fr) 1975-09-22
FR2264531A1 (enExample) 1975-10-17
CA1069517A (en) 1980-01-08
ES435750A1 (es) 1976-12-16
DK139965C (da) 1979-10-29
AU7931075A (en) 1976-09-23
DE2413935A1 (de) 1975-10-16
YU63275A (en) 1982-06-30
DD119229A5 (enExample) 1976-04-12
US4012495A (en) 1977-03-15
SE7503157L (sv) 1975-11-28
HU174074B (hu) 1979-10-28
IE40865L (en) 1975-09-20
NL7503367A (nl) 1975-09-23
CH621338A5 (enExample) 1981-01-30
SE402010B (sv) 1978-06-12
YU40258B (en) 1985-10-31

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