CA1036164A - Derivatives of 2-amino-indane, the preparation and use thereof - Google Patents

Derivatives of 2-amino-indane, the preparation and use thereof

Info

Publication number
CA1036164A
CA1036164A CA193,354A CA193354A CA1036164A CA 1036164 A CA1036164 A CA 1036164A CA 193354 A CA193354 A CA 193354A CA 1036164 A CA1036164 A CA 1036164A
Authority
CA
Canada
Prior art keywords
indane
derivatives
amino
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA193,354A
Other languages
French (fr)
Inventor
Pierre Vanhoof
Pierre Clarebout
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
A Christiaens SA
Original Assignee
A Christiaens SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A Christiaens SA filed Critical A Christiaens SA
Application granted granted Critical
Publication of CA1036164A publication Critical patent/CA1036164A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA193,354A 1973-03-02 1974-02-25 Derivatives of 2-amino-indane, the preparation and use thereof Expired CA1036164A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1030473A GB1468347A (en) 1973-03-02 1973-03-02 Aminoindanes

Publications (1)

Publication Number Publication Date
CA1036164A true CA1036164A (en) 1978-08-08

Family

ID=9965409

Family Applications (1)

Application Number Title Priority Date Filing Date
CA193,354A Expired CA1036164A (en) 1973-03-02 1974-02-25 Derivatives of 2-amino-indane, the preparation and use thereof

Country Status (16)

Country Link
JP (1) JPS547789B2 (en)
AR (3) AR204526A1 (en)
AT (1) AT333742B (en)
BE (1) BE811762A (en)
CA (1) CA1036164A (en)
CH (3) CH605619A5 (en)
DD (2) DD113999A5 (en)
DE (1) DE2409791C3 (en)
ES (1) ES423789A1 (en)
FR (1) FR2219787B1 (en)
GB (1) GB1468347A (en)
HU (1) HU169840B (en)
IL (1) IL44320A (en)
LU (1) LU69535A1 (en)
NL (1) NL7402830A (en)
ZA (1) ZA741232B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1658847A3 (en) * 1999-06-10 2006-07-26 Bridge Pharma, Inc. Indane derivatives as dermal anesthetic agents
EP1185267B1 (en) * 1999-06-10 2006-08-09 Bridge Pharma, Inc. Dermal anesthetic agents
WO2006036936A2 (en) 2004-09-27 2006-04-06 Bridge Pharma, Inc. The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
WO2008011161A2 (en) 2006-07-21 2008-01-24 Bridge Pharma, Inc. Dermal anesthetic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE760018A (en) * 1969-12-19 1971-06-08 Christiaens Sa A NEW DERIVATIVES OF 2-AMINO-INDANE, THEIR PREPARATION AND THEIR USE
JPS4922702A (en) * 1972-06-22 1974-02-28
JPS5216322B2 (en) * 1972-06-22 1977-05-09

Also Published As

Publication number Publication date
IL44320A (en) 1977-06-30
DE2409791B2 (en) 1978-11-16
JPS5029543A (en) 1975-03-25
GB1468347A (en) 1977-03-23
DD112262A5 (en) 1975-04-05
JPS547789B2 (en) 1979-04-10
FR2219787B1 (en) 1978-01-06
DE2409791A1 (en) 1974-09-12
LU69535A1 (en) 1974-06-21
AU6607074A (en) 1975-08-28
AR206652A1 (en) 1976-08-06
DD113999A5 (en) 1975-07-12
BE811762A (en) 1974-09-02
IL44320A0 (en) 1974-05-16
ZA741232B (en) 1975-01-29
AR204526A1 (en) 1976-02-12
NL7402830A (en) 1974-09-04
ES423789A1 (en) 1976-05-16
HU169840B (en) 1977-02-28
CH593909A5 (en) 1977-12-30
AR206653A1 (en) 1976-08-06
CH593910A5 (en) 1977-12-30
FR2219787A1 (en) 1974-09-27
ATA170774A (en) 1976-04-15
CH605619A5 (en) 1978-09-29
DE2409791C3 (en) 1979-07-12
AT333742B (en) 1976-12-10

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