IL46160A0 - Isoquinoline derivatives and processes for their preparation - Google Patents
Isoquinoline derivatives and processes for their preparationInfo
- Publication number
- IL46160A0 IL46160A0 IL46160A IL4616074A IL46160A0 IL 46160 A0 IL46160 A0 IL 46160A0 IL 46160 A IL46160 A IL 46160A IL 4616074 A IL4616074 A IL 4616074A IL 46160 A0 IL46160 A0 IL 46160A0
- Authority
- IL
- Israel
- Prior art keywords
- processes
- preparation
- isoquinoline derivatives
- isoquinoline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2361390A DE2361390A1 (de) | 1973-12-10 | 1973-12-10 | Isochinolinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL46160A0 true IL46160A0 (en) | 1975-02-10 |
Family
ID=5900348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL46160A IL46160A0 (en) | 1973-12-10 | 1974-11-29 | Isoquinoline derivatives and processes for their preparation |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3985881A (cs) |
| JP (1) | JPS5088077A (cs) |
| AT (1) | AT351026B (cs) |
| BE (1) | BE823027A (cs) |
| CA (1) | CA1053675A (cs) |
| CH (1) | CH605776A5 (cs) |
| CS (1) | CS188933B2 (cs) |
| DD (1) | DD115666A5 (cs) |
| DE (1) | DE2361390A1 (cs) |
| DK (1) | DK137007C (cs) |
| ES (1) | ES432716A1 (cs) |
| FR (1) | FR2253522B1 (cs) |
| GB (1) | GB1447611A (cs) |
| HU (1) | HU171483B (cs) |
| IL (1) | IL46160A0 (cs) |
| NL (1) | NL7416050A (cs) |
| SE (1) | SE7415247L (cs) |
| ZA (1) | ZA747820B (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2504250A1 (de) * | 1975-02-01 | 1976-08-05 | Merck Patent Gmbh | Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung |
| US4232160A (en) * | 1978-10-18 | 1980-11-04 | Miles Laboratories, Inc. | Isoquinoline propionamides exhibiting analgesic properties |
| US4556712A (en) * | 1981-05-20 | 1985-12-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines |
| GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
| DE3713743A1 (de) * | 1987-04-24 | 1988-11-17 | Boehringer Ingelheim Kg | Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE68910999T2 (de) * | 1988-02-19 | 1994-03-24 | Smithkline Beecham Farma | 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten. |
| KR890012970A (ko) * | 1988-02-23 | 1989-09-20 | 추후보충 | 테트라히드로 이소퀴놀린 유도체 |
| DE3827727A1 (de) * | 1988-08-16 | 1990-02-22 | Boehringer Ingelheim Kg | Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion |
| GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
| GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
| US5389638A (en) * | 1993-09-10 | 1995-02-14 | Abbott Laboratories | Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors |
| GB0225884D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
| DK2935222T3 (en) * | 2012-12-21 | 2019-01-07 | Epizyme Inc | PRMT5 INHIBITORS AND APPLICATIONS THEREOF |
| US10273213B2 (en) | 2015-09-01 | 2019-04-30 | Merck Patent Gmbh | Method for the production of praziquantel and precursors thereof |
| US20180305334A1 (en) * | 2015-10-14 | 2018-10-25 | Aquinnah Pharmaceuticals, Inc. | Compounds, compositions and methods of use against stress granules |
| PT3684767T (pt) | 2017-09-22 | 2024-07-29 | Jubilant Epipad LLC | Compostos heterocíclicos como inibidores de pad |
| HUE061607T2 (hu) | 2017-10-18 | 2023-07-28 | Jubilant Epipad LLC | Imidazopiridin vegyületek mint PAD inhibitorok |
| BR112020008851A2 (pt) | 2017-11-06 | 2020-10-20 | Jubilant Prodel LLC | composto da fórmula i, processo de preparação de compostos da fórmula i, composição farmacêutica, método para o tratamento e/ou prevenção de várias doenças, uso, método para o tratamento de câncer, método de tratamento de câncer e método para o tratamento e/ou prevenção de câncer e doenças infecciosas |
| BR112020010322A2 (pt) | 2017-11-24 | 2020-11-17 | Jubilant Episcribe Llc | composto da fórmula i; composto da fórmula ia; composto da fórmula ib; processo de preparação de compostos da fórmula i; composição farmacêutica; método para o tratamento e/ou prevenção de várias doenças; uso dos compostos; método para o tratamento de câncer; e método para o tratamento e/ou prevenção de uma afecção mediada por prmt5 ou um distúrbio proliferativo ou câncer |
| SG11202008950PA (en) | 2018-03-13 | 2020-10-29 | Jubilant Prodel LLC | Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2612503A (en) * | 1949-04-19 | 1952-09-30 | Smith Kline French Lab | Basic ether-substituted isoquinolines |
| US2640829A (en) * | 1950-11-10 | 1953-06-02 | Smith Kline French Lab | Isoquinolyl heterocyclic ethers |
| US3021331A (en) * | 1959-07-20 | 1962-02-13 | Pfizer & Co C | Azabenzopyridocolines |
| US3483206A (en) * | 1967-12-15 | 1969-12-09 | Ciba Geigy Corp | N-isoquinolylalkanoyl-n-arylamines |
| US3600394A (en) * | 1968-05-17 | 1971-08-17 | Searle & Co | 2-aminoalkyl-3-arylisocarbostyrils |
-
1973
- 1973-12-10 DE DE2361390A patent/DE2361390A1/de active Pending
-
1974
- 1974-11-29 IL IL46160A patent/IL46160A0/xx unknown
- 1974-12-05 SE SE7415247A patent/SE7415247L/xx unknown
- 1974-12-06 CA CA215,386A patent/CA1053675A/en not_active Expired
- 1974-12-06 FR FR7440041A patent/FR2253522B1/fr not_active Expired
- 1974-12-06 CS CS748365A patent/CS188933B2/cs unknown
- 1974-12-06 BE BE151221A patent/BE823027A/xx unknown
- 1974-12-09 DD DD182514A patent/DD115666A5/xx unknown
- 1974-12-09 DK DK639674A patent/DK137007C/da active
- 1974-12-09 JP JP49141945A patent/JPS5088077A/ja active Pending
- 1974-12-09 GB GB5319174A patent/GB1447611A/en not_active Expired
- 1974-12-09 ES ES432716A patent/ES432716A1/es not_active Expired
- 1974-12-09 CH CH1632774A patent/CH605776A5/xx not_active IP Right Cessation
- 1974-12-09 AT AT981974A patent/AT351026B/de not_active IP Right Cessation
- 1974-12-09 ZA ZA00747820A patent/ZA747820B/xx unknown
- 1974-12-09 US US05/530,551 patent/US3985881A/en not_active Expired - Lifetime
- 1974-12-09 HU HU74ME00001812A patent/HU171483B/hu unknown
- 1974-12-10 NL NL7416050A patent/NL7416050A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US3985881A (en) | 1976-10-12 |
| ATA981974A (de) | 1978-12-15 |
| BE823027A (fr) | 1975-06-06 |
| FR2253522A1 (cs) | 1975-07-04 |
| GB1447611A (en) | 1976-08-25 |
| DE2361390A1 (de) | 1975-06-19 |
| PL93405B1 (cs) | 1977-05-30 |
| JPS5088077A (cs) | 1975-07-15 |
| CH605776A5 (cs) | 1978-10-13 |
| AU7625774A (en) | 1976-06-10 |
| ZA747820B (en) | 1975-12-31 |
| SE7415247L (cs) | 1975-06-11 |
| NL7416050A (nl) | 1975-06-12 |
| CS188933B2 (en) | 1979-03-30 |
| ES432716A1 (es) | 1977-03-01 |
| HU171483B (hu) | 1978-01-28 |
| FR2253522B1 (cs) | 1978-06-30 |
| DK137007C (da) | 1978-06-05 |
| DD115666A5 (cs) | 1975-10-12 |
| AT351026B (de) | 1979-07-10 |
| DK639674A (cs) | 1975-08-11 |
| CA1053675A (en) | 1979-05-01 |
| DK137007B (da) | 1978-01-02 |
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