IL44262A - 7alpha-aminoacylamido-3-halo-3-cephem 4-carboxylic acids and process for their preparation - Google Patents
7alpha-aminoacylamido-3-halo-3-cephem 4-carboxylic acids and process for their preparationInfo
- Publication number
- IL44262A IL44262A IL44262A IL4426274A IL44262A IL 44262 A IL44262 A IL 44262A IL 44262 A IL44262 A IL 44262A IL 4426274 A IL4426274 A IL 4426274A IL 44262 A IL44262 A IL 44262A
- Authority
- IL
- Israel
- Prior art keywords
- cephem
- chloro
- compound
- ester
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33538173A | 1973-02-23 | 1973-02-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL44262A0 IL44262A0 (en) | 1974-05-16 |
| IL44262A true IL44262A (en) | 1977-08-31 |
Family
ID=23311540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL44262A IL44262A (en) | 1973-02-23 | 1974-02-22 | 7alpha-aminoacylamido-3-halo-3-cephem 4-carboxylic acids and process for their preparation |
Country Status (37)
| Country | Link |
|---|---|
| JP (4) | JPS6139313B2 (xx) |
| AR (1) | AR199510A1 (xx) |
| AT (1) | AT333953B (xx) |
| BE (1) | BE811495A (xx) |
| BR (1) | BR7401384D0 (xx) |
| CA (1) | CA1016537A (xx) |
| CH (1) | CH593988A5 (xx) |
| CS (1) | CS187409B2 (xx) |
| CY (1) | CY1043A (xx) |
| DD (1) | DD110278A5 (xx) |
| DE (1) | DE2408698C2 (xx) |
| DK (1) | DK153157C (xx) |
| EG (1) | EG11104A (xx) |
| ES (1) | ES423531A1 (xx) |
| FI (1) | FI63035C (xx) |
| FR (1) | FR2218877B1 (xx) |
| GB (1) | GB1461323A (xx) |
| GT (1) | GT197432133A (xx) |
| HK (1) | HK20080A (xx) |
| HU (1) | HU166849B (xx) |
| IE (1) | IE39046B1 (xx) |
| IL (1) | IL44262A (xx) |
| IN (1) | IN139620B (xx) |
| KE (1) | KE3027A (xx) |
| MW (1) | MW674A1 (xx) |
| MY (1) | MY8100024A (xx) |
| NL (1) | NL179057C (xx) |
| NO (2) | NO148375C (xx) |
| OA (1) | OA04809A (xx) |
| PH (1) | PH9616A (xx) |
| PL (1) | PL88702B1 (xx) |
| RO (1) | RO64663A (xx) |
| SE (1) | SE411212B (xx) |
| SU (1) | SU676166A3 (xx) |
| YU (1) | YU36970B (xx) |
| ZA (1) | ZA741191B (xx) |
| ZM (1) | ZM3574A1 (xx) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT342197B (de) * | 1975-02-20 | 1978-03-28 | Ciba Geigy Ag | Neues verfahren zur herstellung von 3-cephemverbindungen |
| CH619233A5 (xx) * | 1975-07-31 | 1980-09-15 | Ciba Geigy Ag | |
| CH622802A5 (xx) * | 1975-08-20 | 1981-04-30 | Ciba Geigy Ag | |
| IE45158B1 (en) * | 1976-08-16 | 1982-06-30 | Lilly Co Eli | 3-chloro-cephem synthesis |
| DE3508258A1 (de) * | 1985-03-08 | 1986-09-18 | Bayer Ag, 5090 Leverkusen | Ss-lactamantibiotika, verfahren zur herstellung und ihre verwendung als und in arzneimitteln |
| DE3509618A1 (de) | 1985-03-16 | 1986-09-18 | Bayer Ag, 5090 Leverkusen | Ss-lactam-antibiotika, verfahren zur herstellung und ihre verwendung als arzneimittel |
| JPS6436445U (xx) * | 1987-08-28 | 1989-03-06 | ||
| DE3803169A1 (de) | 1988-02-03 | 1989-08-17 | Bayer Ag | Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln |
| ES2010075A6 (es) * | 1989-01-10 | 1989-10-16 | Antibioticos Sa | Un procedimiento para la preparacion de compuestos de 3-cloro-cefem. |
| JP2539459Y2 (ja) * | 1991-12-18 | 1997-06-25 | 三重ホーロー株式会社 | 組立式塵芥焼却器 |
| IT1255458B (it) * | 1992-05-11 | 1995-11-02 | Col Marco Da | Procedimento per la preparazione di derivati beta-lattamici alogenati |
| ES2079327B1 (es) | 1994-12-13 | 1996-08-01 | Lilly Sa | Formulaciones farmaceuticas de cefaclor. |
| CN101805357B (zh) * | 2010-04-28 | 2012-01-11 | 陶灵刚 | 一种头孢克洛化合物及其制法 |
| CN103588790A (zh) * | 2013-11-29 | 2014-02-19 | 中国科学院长春应用化学研究所 | 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法 |
| CN106632400A (zh) * | 2016-12-16 | 2017-05-10 | 石家庄柏奇化工有限公司 | Pd‑C催化氢化脱除4‑硝基苄基制备7‑ACCA的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3641021A (en) * | 1969-04-18 | 1972-02-08 | Lilly Co Eli | 3 7-(ring-substituted) cephalosporin compounds |
| FR2143211B1 (xx) * | 1971-06-24 | 1975-10-31 | Fujisawa Pharmaceutical Co | |
| AR206201A1 (es) * | 1972-06-29 | 1976-07-07 | Ciba Geigy Ag | Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos |
-
1974
- 1974-02-18 YU YU0399/74A patent/YU36970B/xx unknown
- 1974-02-21 AT AT142574A patent/AT333953B/de not_active IP Right Cessation
- 1974-02-22 DK DK095274A patent/DK153157C/da not_active IP Right Cessation
- 1974-02-22 AR AR252493A patent/AR199510A1/es active
- 1974-02-22 DE DE2408698A patent/DE2408698C2/de not_active Expired
- 1974-02-22 IL IL44262A patent/IL44262A/en unknown
- 1974-02-22 GB GB809774A patent/GB1461323A/en not_active Expired
- 1974-02-22 HU HUEI528A patent/HU166849B/hu unknown
- 1974-02-22 CA CA193,236A patent/CA1016537A/en not_active Expired
- 1974-02-22 MW MW6/74*UA patent/MW674A1/xx unknown
- 1974-02-22 NL NLAANVRAGE7402489,A patent/NL179057C/xx not_active IP Right Cessation
- 1974-02-22 SU SU742000614A patent/SU676166A3/ru active
- 1974-02-22 BE BE1005741A patent/BE811495A/xx not_active IP Right Cessation
- 1974-02-22 GT GT197432133A patent/GT197432133A/es unknown
- 1974-02-22 ES ES423531A patent/ES423531A1/es not_active Expired
- 1974-02-22 ZA ZA00741191A patent/ZA741191B/xx unknown
- 1974-02-22 SE SE7402413A patent/SE411212B/xx not_active IP Right Cessation
- 1974-02-22 CY CY1043A patent/CY1043A/xx unknown
- 1974-02-22 BR BR1384/74A patent/BR7401384D0/pt unknown
- 1974-02-22 IE IE00356/74A patent/IE39046B1/en unknown
- 1974-02-22 ZM ZM35/74A patent/ZM3574A1/xx unknown
- 1974-02-22 IN IN381/CAL/74A patent/IN139620B/en unknown
- 1974-02-22 FI FI525/74A patent/FI63035C/fi active
- 1974-02-22 DD DD176751A patent/DD110278A5/xx unknown
- 1974-02-22 FR FR7406153A patent/FR2218877B1/fr not_active Expired
- 1974-02-22 NO NO740606A patent/NO148375C/no unknown
- 1974-02-22 PH PH15540*UA patent/PH9616A/en unknown
- 1974-02-23 JP JP49021870A patent/JPS6139313B2/ja not_active Expired
- 1974-02-23 PL PL1974169035A patent/PL88702B1/pl unknown
- 1974-02-23 EG EG52/74A patent/EG11104A/xx active
- 1974-02-23 RO RO7477796A patent/RO64663A/ro unknown
- 1974-02-23 OA OA55128A patent/OA04809A/xx unknown
- 1974-02-25 CH CH265374A patent/CH593988A5/xx not_active IP Right Cessation
- 1974-02-25 CS CS741376A patent/CS187409B2/cs unknown
-
1979
- 1979-08-16 NO NO792681A patent/NO148377C/no unknown
-
1980
- 1980-02-27 KE KE3027A patent/KE3027A/xx unknown
- 1980-04-17 HK HK200/80A patent/HK20080A/xx unknown
-
1981
- 1981-02-20 JP JP2533081A patent/JPS56138192A/ja active Granted
- 1981-02-20 JP JP2532981A patent/JPS56138191A/ja active Granted
- 1981-02-20 JP JP2532881A patent/JPS56138190A/ja active Granted
- 1981-12-30 MY MY24/81A patent/MY8100024A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3925372A (en) | Alpha-aminoacyl-3-halo cephalosporins | |
| US3992377A (en) | 3-Thio-substituted cephalosporin antibiotics | |
| US3962227A (en) | 3-halo cephalosporins | |
| IL44262A (en) | 7alpha-aminoacylamido-3-halo-3-cephem 4-carboxylic acids and process for their preparation | |
| FI60870B (fi) | Foerfarande foer framstaellning av farmakologiskt vaerdefulla o-substituerade 7beta-amino-3-cefem-3-01-4-karbonsyrafoereningar | |
| US4064343A (en) | 3-Halo cephalosporins | |
| US4181733A (en) | Carboxyl derivatives of thienamycin | |
| IE43845B1 (en) | 4-thia-1-azabicyclo/4.2.0/oct-2-ene derivatives | |
| US3849408A (en) | 4-substituted-delta2-cephalosporin derivatives | |
| US3917588A (en) | {60 -Aminoacyl cephalosporin ethers | |
| US4122086A (en) | Isopenicillins | |
| US4492692A (en) | Cephalosporin derivatives | |
| US4008229A (en) | Halo substituted β-lactam antibiotics | |
| US4208515A (en) | 3-Halo cephalosporins | |
| FI63240B (fi) | Analogifoerfarande foer framstaellning av antibakteriella 3-klorcefalosporinderivat | |
| US4252950A (en) | 3-Halo cephalosporins | |
| US4281116A (en) | 3-Halo cephalosporins | |
| KR870000528B1 (ko) | 3-아지도 세팔로스포린의 제조방법 | |
| US4103086A (en) | 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives | |
| US4260745A (en) | 3-Halo cephalosporins | |
| US3985737A (en) | 3-Sulfonate esters of cephalosporin | |
| DE2555182A1 (de) | 3-(1-hydroxyalkyl- oder -1-hydroxyarylalkyl)cepheme und derivate hiervon | |
| JPH0521912B2 (xx) | ||
| EP0122158A2 (en) | Improvements in or relating to benzothienyl cephalosporin antibiotics | |
| CA1043332A (en) | 3,4-dicarboxycephalosporins and derivatives |