FR2218877A1 - - Google Patents

Info

Publication number
FR2218877A1
FR2218877A1 FR7406153A FR7406153A FR2218877A1 FR 2218877 A1 FR2218877 A1 FR 2218877A1 FR 7406153 A FR7406153 A FR 7406153A FR 7406153 A FR7406153 A FR 7406153A FR 2218877 A1 FR2218877 A1 FR 2218877A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7406153A
Other languages
French (fr)
Other versions
FR2218877B1 (xx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2218877A1 publication Critical patent/FR2218877A1/fr
Application granted granted Critical
Publication of FR2218877B1 publication Critical patent/FR2218877B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FR7406153A 1973-02-23 1974-02-22 Expired FR2218877B1 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33538173A 1973-02-23 1973-02-23

Publications (2)

Publication Number Publication Date
FR2218877A1 true FR2218877A1 (xx) 1974-09-20
FR2218877B1 FR2218877B1 (xx) 1977-03-11

Family

ID=23311540

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7406153A Expired FR2218877B1 (xx) 1973-02-23 1974-02-22

Country Status (37)

Country Link
JP (4) JPS6139313B2 (xx)
AR (1) AR199510A1 (xx)
AT (1) AT333953B (xx)
BE (1) BE811495A (xx)
BR (1) BR7401384D0 (xx)
CA (1) CA1016537A (xx)
CH (1) CH593988A5 (xx)
CS (1) CS187409B2 (xx)
CY (1) CY1043A (xx)
DD (1) DD110278A5 (xx)
DE (1) DE2408698C2 (xx)
DK (1) DK153157C (xx)
EG (1) EG11104A (xx)
ES (1) ES423531A1 (xx)
FI (1) FI63035C (xx)
FR (1) FR2218877B1 (xx)
GB (1) GB1461323A (xx)
GT (1) GT197432133A (xx)
HK (1) HK20080A (xx)
HU (1) HU166849B (xx)
IE (1) IE39046B1 (xx)
IL (1) IL44262A (xx)
IN (1) IN139620B (xx)
KE (1) KE3027A (xx)
MW (1) MW674A1 (xx)
MY (1) MY8100024A (xx)
NL (1) NL179057C (xx)
NO (2) NO148375C (xx)
OA (1) OA04809A (xx)
PH (1) PH9616A (xx)
PL (1) PL88702B1 (xx)
RO (1) RO64663A (xx)
SE (1) SE411212B (xx)
SU (1) SU676166A3 (xx)
YU (1) YU36970B (xx)
ZA (1) ZA741191B (xx)
ZM (1) ZM3574A1 (xx)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0377958A2 (en) * 1989-01-10 1990-07-18 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds
EP0570058A2 (en) * 1992-05-11 1993-11-18 Biochimica Opos Spa Process for the preparation of halogenated beta-lactam compounds

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
CH619233A5 (xx) * 1975-07-31 1980-09-15 Ciba Geigy Ag
CH622802A5 (xx) * 1975-08-20 1981-04-30 Ciba Geigy Ag
IE45158B1 (en) * 1976-08-16 1982-06-30 Lilly Co Eli 3-chloro-cephem synthesis
DE3508258A1 (de) * 1985-03-08 1986-09-18 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zur herstellung und ihre verwendung als und in arzneimitteln
DE3509618A1 (de) * 1985-03-16 1986-09-18 Bayer Ag, 5090 Leverkusen Ss-lactam-antibiotika, verfahren zur herstellung und ihre verwendung als arzneimittel
JPS6436445U (xx) * 1987-08-28 1989-03-06
DE3803169A1 (de) 1988-02-03 1989-08-17 Bayer Ag Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln
JP2539459Y2 (ja) * 1991-12-18 1997-06-25 三重ホーロー株式会社 組立式塵芥焼却器
ES2079327B1 (es) 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
CN101805357B (zh) * 2010-04-28 2012-01-11 陶灵刚 一种头孢克洛化合物及其制法
CN103588790A (zh) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法
CN106632400A (zh) * 2016-12-16 2017-05-10 石家庄柏奇化工有限公司 Pd‑C催化氢化脱除4‑硝基苄基制备7‑ACCA的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2143211A1 (xx) * 1971-06-24 1973-02-02 Fujisawa Pharmaceutical Co

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2143211A1 (xx) * 1971-06-24 1973-02-02 Fujisawa Pharmaceutical Co

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0377958A2 (en) * 1989-01-10 1990-07-18 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds
EP0377958A3 (en) * 1989-01-10 1992-01-08 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds
EP0570058A2 (en) * 1992-05-11 1993-11-18 Biochimica Opos Spa Process for the preparation of halogenated beta-lactam compounds
EP0570058A3 (xx) * 1992-05-11 1994-03-23 Opos Biochimica Srl
US5532353A (en) * 1992-05-11 1996-07-02 Biochimica Opos Spa Process for the preparation of halogenated β-lactam compounds

Also Published As

Publication number Publication date
JPS56138192A (en) 1981-10-28
CA1016537A (en) 1977-08-30
AT333953B (de) 1976-12-27
AR199510A1 (es) 1974-09-09
NO148377C (no) 1983-09-28
BR7401384D0 (pt) 1974-11-05
YU39974A (en) 1982-06-18
NO148375B (no) 1983-06-20
ZM3574A1 (en) 1975-11-21
NO740606L (no) 1974-08-26
RO64663A (fr) 1979-02-15
JPS6140237B2 (xx) 1986-09-08
NL179057C (nl) 1986-07-01
ZA741191B (en) 1975-10-29
FR2218877B1 (xx) 1977-03-11
CH593988A5 (xx) 1977-12-30
CS187409B2 (en) 1979-01-31
EG11104A (en) 1976-12-31
BE811495A (fr) 1974-08-22
DK153157B (da) 1988-06-20
NL179057B (nl) 1986-02-03
SE411212B (sv) 1979-12-10
GT197432133A (es) 1975-08-16
ATA142574A (de) 1976-04-15
IL44262A0 (en) 1974-05-16
DD110278A5 (xx) 1974-12-12
DE2408698A1 (de) 1974-09-05
JPS56138190A (en) 1981-10-28
JPS6139313B2 (xx) 1986-09-03
NO792681L (no) 1974-08-26
YU36970B (en) 1984-08-31
IL44262A (en) 1977-08-31
NO148377B (no) 1983-06-20
CY1043A (en) 1980-08-01
IN139620B (xx) 1976-07-10
HK20080A (en) 1980-04-25
JPS49110689A (xx) 1974-10-22
MY8100024A (en) 1981-12-31
NO148375C (no) 1983-09-28
JPS6140236B2 (xx) 1986-09-08
HU166849B (xx) 1975-06-28
MW674A1 (en) 1975-04-09
PH9616A (en) 1976-01-20
IE39046L (en) 1974-08-23
JPS56138191A (en) 1981-10-28
FI63035B (fi) 1982-12-31
PL88702B1 (xx) 1976-09-30
DE2408698C2 (de) 1983-11-10
DK153157C (da) 1988-10-31
FI63035C (fi) 1983-04-11
AU6591674A (en) 1975-08-28
IE39046B1 (en) 1978-07-19
JPS6140235B2 (xx) 1986-09-08
OA04809A (fr) 1980-08-31
GB1461323A (en) 1977-01-13
KE3027A (en) 1980-03-14
SU676166A3 (ru) 1979-07-25
ES423531A1 (es) 1976-05-16
NL7402489A (xx) 1974-08-27

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0052, 920323

CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0074, 920415

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0074, 740722

CL Concession to grant licences