IT1255458B - Procedimento per la preparazione di derivati beta-lattamici alogenati - Google Patents

Procedimento per la preparazione di derivati beta-lattamici alogenati

Info

Publication number
IT1255458B
IT1255458B ITMI921125A ITMI921125A IT1255458B IT 1255458 B IT1255458 B IT 1255458B IT MI921125 A ITMI921125 A IT MI921125A IT MI921125 A ITMI921125 A IT MI921125A IT 1255458 B IT1255458 B IT 1255458B
Authority
IT
Italy
Prior art keywords
preparation
derivatives
lactamic
procedure
halogenated
Prior art date
Application number
ITMI921125A
Other languages
English (en)
Inventor
Col Marco Da
Asta Leone Dall
Irene Resta
Gianfranco Cainelli
Michele Contento
Mauro Panunzio
Ronchi Achille Umani
Original Assignee
Col Marco Da
Dall'asta Leone
Irene Resta
Gianfranco Cainelli
Michele Contento
Mauro Panunzio
Ronchi Achille Umani
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Col Marco Da, Dall'asta Leone, Irene Resta, Gianfranco Cainelli, Michele Contento, Mauro Panunzio, Ronchi Achille Umani filed Critical Col Marco Da
Priority to ITMI921125A priority Critical patent/IT1255458B/it
Publication of ITMI921125A0 publication Critical patent/ITMI921125A0/it
Priority to EP93201290A priority patent/EP0570058A2/en
Priority to US08/058,714 priority patent/US5532353A/en
Publication of ITMI921125A1 publication Critical patent/ITMI921125A1/it
Application granted granted Critical
Publication of IT1255458B publication Critical patent/IT1255458B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Si descrive la preparazione di derivati ?-lattamici alogenati mediante introduzione di un atomo di cloro in posizione 3 del nucleo cefemico a partire da un 3-solfonilossicefem. Tali prodotti di partenza vengono posti a reagire con un donatore di ioni cloro in ambiente basico.
ITMI921125A 1992-05-11 1992-05-11 Procedimento per la preparazione di derivati beta-lattamici alogenati IT1255458B (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITMI921125A IT1255458B (it) 1992-05-11 1992-05-11 Procedimento per la preparazione di derivati beta-lattamici alogenati
EP93201290A EP0570058A2 (en) 1992-05-11 1993-05-07 Process for the preparation of halogenated beta-lactam compounds
US08/058,714 US5532353A (en) 1992-05-11 1993-05-10 Process for the preparation of halogenated β-lactam compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921125A IT1255458B (it) 1992-05-11 1992-05-11 Procedimento per la preparazione di derivati beta-lattamici alogenati

Publications (3)

Publication Number Publication Date
ITMI921125A0 ITMI921125A0 (it) 1992-05-11
ITMI921125A1 ITMI921125A1 (it) 1993-11-11
IT1255458B true IT1255458B (it) 1995-11-02

Family

ID=11363263

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI921125A IT1255458B (it) 1992-05-11 1992-05-11 Procedimento per la preparazione di derivati beta-lattamici alogenati

Country Status (3)

Country Link
US (1) US5532353A (it)
EP (1) EP0570058A2 (it)
IT (1) IT1255458B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104910185B (zh) * 2015-03-10 2018-02-16 国药集团致君（苏州）制药有限公司 一种头孢洛林酯中间体母核的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR208068A1 (es) * 1973-02-23 1976-11-30 Lilly Co Eli Un procedimiento para preparar derivados de acidos 7-acilamido-3-halo-cefem-4-carboxilico los esteres y las sales farmaceuticamente aceptables de los mismos
YU36970B (en) * 1973-02-23 1984-08-31 Lilly Co Eli Process for obtaining 7-(amino)-acylamido-3-halocephalosporins
US3926978A (en) * 1974-02-06 1975-12-16 Lilly Co Eli Process for preparing 3-fluorocephalosporins
US4064343A (en) * 1974-04-01 1977-12-20 Eli Lilly And Company 3-Halo cephalosporins
US5043439A (en) * 1990-03-08 1991-08-27 Bristol-Myers Squibb Company Process for production of cephalosporins

Also Published As

Publication number Publication date
EP0570058A3 (it) 1994-03-23
US5532353A (en) 1996-07-02
ITMI921125A1 (it) 1993-11-11
ITMI921125A0 (it) 1992-05-11
EP0570058A2 (en) 1993-11-18

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970529