IL40686A - 2-amino-imidazo(5,1-f)-as-triazin-4(3h)-ones,their preparation and pharmaceutical compositions containing them - Google Patents

2-amino-imidazo(5,1-f)-as-triazin-4(3h)-ones,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL40686A
IL40686A IL40686A IL4068672A IL40686A IL 40686 A IL40686 A IL 40686A IL 40686 A IL40686 A IL 40686A IL 4068672 A IL4068672 A IL 4068672A IL 40686 A IL40686 A IL 40686A
Authority
IL
Israel
Prior art keywords
triazin
imidazo
ones
amino
preparation
Prior art date
Application number
IL40686A
Other languages
English (en)
Other versions
IL40686A0 (en
Original Assignee
Allen & Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allen & Hanburys Ltd filed Critical Allen & Hanburys Ltd
Publication of IL40686A0 publication Critical patent/IL40686A0/xx
Publication of IL40686A publication Critical patent/IL40686A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL40686A 1971-11-19 1972-10-27 2-amino-imidazo(5,1-f)-as-triazin-4(3h)-ones,their preparation and pharmaceutical compositions containing them IL40686A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5375071A GB1400999A (en) 1971-11-19 1971-11-19 Imidazo-triazine compounds and their use in therapeutic compositions

Publications (2)

Publication Number Publication Date
IL40686A0 IL40686A0 (en) 1972-12-29
IL40686A true IL40686A (en) 1975-12-31

Family

ID=10468856

Family Applications (1)

Application Number Title Priority Date Filing Date
IL40686A IL40686A (en) 1971-11-19 1972-10-27 2-amino-imidazo(5,1-f)-as-triazin-4(3h)-ones,their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US3840537A (cs)
JP (1) JPS563873B2 (cs)
AT (1) AT321923B (cs)
AU (1) AU472127B2 (cs)
BE (1) BE791025A (cs)
CA (1) CA990292A (cs)
CH (1) CH594671A5 (cs)
DE (1) DE2255172A1 (cs)
DK (1) DK138691B (cs)
ES (1) ES408736A1 (cs)
FR (1) FR2160407B1 (cs)
GB (1) GB1400999A (cs)
IE (1) IE37046B1 (cs)
IL (1) IL40686A (cs)
NL (1) NL7215646A (cs)
PH (1) PH9669A (cs)
SE (1) SE402915B (cs)
ZA (1) ZA727532B (cs)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1457873A (en) * 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
DE2314488C3 (de) * 1973-03-23 1979-01-04 C.H. Boehringer Sohn, 6507 Ingelheim 8-(2,6-Dichlorphenyl)-7-(4-chlorphenyl)-5-oxo-233,8-tetrahydro-imidazo [1,2-a] -s-triazin, Verfahren zu dessen Herstellung und dieses enthaltene Arzneimittel
DE2335193A1 (de) * 1973-07-11 1975-01-30 Hoechst Ag Bis-triazinobenzimidazole und ihre herstellung
US4115572A (en) * 1977-02-03 1978-09-19 American Cyanamid Company Imidazo-[1,5-d]-as-triazin-1(2H)-ones and method of ameliorating asthma
USRE30511E (en) * 1977-02-03 1981-02-10 American Cyanamid Company Imidazo[1,5-d]-as-triazine-4(3H)-ones and thiones
US4107307A (en) * 1977-02-03 1978-08-15 American Cyanamid Company Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones
DK109578A (da) * 1977-03-25 1978-09-26 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af heterocycliske forbindelser
US4107308A (en) * 1977-10-18 1978-08-15 American Cyanamid Company Imidazo[1,5-d]-as-triazines
US4308384A (en) * 1978-09-18 1981-12-29 Glaxo Group Limited Production of triazinones
HU187474B (en) * 1981-11-18 1986-01-28 Gyogyszerkutato Intezet,Hu Process for producing new spiro-pyrazole-square bracket-1,5-d-square bracket closed-square bracket-1,2,4-square bracket closed-triazine derivatives
US4395547A (en) * 1982-02-10 1983-07-26 American Cyanamid Co. Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
US6624181B1 (en) * 1997-02-28 2003-09-23 Altana Pharma Ag Synergistic combination
DK1049695T3 (da) * 1997-11-12 2002-05-13 Bayer Ag 2-Phenyl-substituerede imidazotriazinoner som phosphodiesterase-inhibitorer
DE19827640A1 (de) * 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
EP1107747A4 (en) 1998-08-26 2003-04-23 Smithkline Beecham Corp COMPOSITIONS FOR THE TREATMENT OF PULMONARY DISEASES
IL147688A0 (en) * 1999-08-21 2002-08-14 Byk Gulden Lomberg Chem Fab Synergistic combination
MXPA03010119A (es) * 2001-05-09 2005-03-07 Bayer Healthcare Ag Nuevo uso de imidazotriazinonas 2-fenilo sustituidas.
GB0113343D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel Heterocycles 2
GB0113344D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel heterocycles 3
DE10135815A1 (de) 2001-07-23 2003-02-06 Bayer Ag Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
US7462614B2 (en) * 2003-04-01 2008-12-09 Smithkline Beecham Corporation Imidazotriazine compounds
AP2139A (en) 2004-04-02 2010-08-21 Osi Pharm Inc 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors.
DE102005001989A1 (de) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009240A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
WO2007039075A2 (en) * 2005-09-29 2007-04-12 Bayer Healthcare Ag Pde inhibitors and combinations thereof for the treatment of urological disorders
PL1951724T3 (pl) * 2005-11-17 2011-09-30 Osi Pharmaceuticals Llc SKONDENSOWANE BICYKLICZNE INHIBITORY mTOR
CN101711153A (zh) * 2007-06-13 2010-05-19 拜耳先灵制药股份公司 用于治疗听觉损伤的pde抑制剂
KR20120020099A (ko) 2009-04-20 2012-03-07 오에스아이 파마슈티컬스, 엘엘씨 Ｃ-피라진-메틸아민의 제조
CN103374002B (zh) * 2012-04-19 2015-07-15 山东轩竹医药科技有限公司 磷酸二酯酶-5抑制剂
TW201639851A (zh) * 2015-03-16 2016-11-16 大日本住友製藥股份有限公司 雙環咪唑衍生物
WO2017000276A1 (en) * 2015-07-01 2017-01-05 Merck Sharp & Dohme Corp. Bicyclic heterocyclic compounds as pde2 inhibitors
WO2017204316A1 (ja) * 2016-05-27 2017-11-30 塩野義製薬株式会社 ５－オキソ－１，２，４－トリアジン誘導体およびその医薬組成物

Also Published As

Publication number Publication date
US3840537A (en) 1974-10-08
AT321923B (de) 1975-04-25
ZA727532B (en) 1973-07-25
JPS4857993A (cs) 1973-08-14
DK138691B (da) 1978-10-16
CH594671A5 (cs) 1978-01-13
DE2255172A1 (de) 1973-05-24
DK138691C (cs) 1979-03-26
AU4819172A (en) 1974-05-16
FR2160407A1 (cs) 1973-06-29
IE37046L (en) 1973-05-19
IL40686A0 (en) 1972-12-29
GB1400999A (en) 1975-07-16
ES408736A1 (es) 1976-03-01
AU472127B2 (en) 1976-05-20
IE37046B1 (en) 1977-04-27
FR2160407B1 (cs) 1975-10-17
SE402915B (sv) 1978-07-24
BE791025A (fr) 1973-05-07
CA990292A (en) 1976-06-01
PH9669A (en) 1976-02-10
NL7215646A (cs) 1973-05-22
JPS563873B2 (cs) 1981-01-27

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