IL310729A - Cd80 variant immunomodulatory proteins and uses thereof - Google Patents

Cd80 variant immunomodulatory proteins and uses thereof

Info

Publication number
IL310729A
IL310729A IL310729A IL31072924A IL310729A IL 310729 A IL310729 A IL 310729A IL 310729 A IL310729 A IL 310729A IL 31072924 A IL31072924 A IL 31072924A IL 310729 A IL310729 A IL 310729A
Authority
IL
Israel
Prior art keywords
polypeptide
variant
fold
cell
amino acid
Prior art date
Application number
IL310729A
Other languages
English (en)
Hebrew (he)
Original Assignee
Alpine Immune Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpine Immune Sciences Inc filed Critical Alpine Immune Sciences Inc
Publication of IL310729A publication Critical patent/IL310729A/en

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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
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IL310729A 2016-04-15 2017-04-14 Cd80 variant immunomodulatory proteins and uses thereof IL310729A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662323595P 2016-04-15 2016-04-15
US201662394743P 2016-09-14 2016-09-14
US201662410844P 2016-10-20 2016-10-20
US201762472570P 2017-03-16 2017-03-16
US201762475201P 2017-03-22 2017-03-22
PCT/US2017/027817 WO2017181152A2 (en) 2016-04-15 2017-04-14 Cd80 variant immunomodulatory proteins and uses thereof

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IL310729A true IL310729A (en) 2024-04-01

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IL262366A IL262366B2 (en) 2016-04-15 2017-04-14 Immunomodulatory proteins and CD80 variants and their uses
IL310729A IL310729A (en) 2016-04-15 2017-04-14 Cd80 variant immunomodulatory proteins and uses thereof

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IL262366A IL262366B2 (en) 2016-04-15 2017-04-14 Immunomodulatory proteins and CD80 variants and their uses

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US (5) US11078282B2 (OSRAM)
EP (1) EP3443000B1 (OSRAM)
JP (3) JP7527758B2 (OSRAM)
KR (3) KR20190006495A (OSRAM)
CN (1) CN109715657A (OSRAM)
AU (2) AU2017248830B2 (OSRAM)
CA (1) CA3019202A1 (OSRAM)
IL (2) IL262366B2 (OSRAM)
MA (1) MA43552A (OSRAM)
NZ (2) NZ787233A (OSRAM)
SG (1) SG11201808783XA (OSRAM)
WO (1) WO2017181152A2 (OSRAM)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3283508B1 (en) * 2015-04-17 2021-03-17 Alpine Immune Sciences, Inc. Immunomodulatory proteins with tunable affinities
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