IL281098A - Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof - Google Patents

Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof

Info

Publication number
IL281098A
IL281098A IL281098A IL28109821A IL281098A IL 281098 A IL281098 A IL 281098A IL 281098 A IL281098 A IL 281098A IL 28109821 A IL28109821 A IL 28109821A IL 281098 A IL281098 A IL 281098A
Authority
IL
Israel
Prior art keywords
structures
chimeric antigen
antigen receptors
receptors against
against mesothelin
Prior art date
Application number
IL281098A
Other languages
English (en)
Hebrew (he)
Inventor
Shuai Yang
Shu Wu
Qing Dai
Jian Liu
Kun Jiang
Yuanyuan Peng
Chen Hu
Original Assignee
Nanjing Legend Biotech Co Ltd
Shuai Yang
Shu Wu
Qing Dai
Jian Liu
Kun Jiang
Yuanyuan Peng
Chen Hu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Legend Biotech Co Ltd, Shuai Yang, Shu Wu, Qing Dai, Jian Liu, Kun Jiang, Yuanyuan Peng, Chen Hu filed Critical Nanjing Legend Biotech Co Ltd
Publication of IL281098A publication Critical patent/IL281098A/en

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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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IL281098A 2018-08-29 2021-02-24 Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof IL281098A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2018103050 2018-08-29
CN2019083918 2019-04-23
PCT/CN2019/103215 WO2020043152A1 (en) 2018-08-29 2019-08-29 Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof

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US (1) US11932698B2 (https=)
EP (1) EP3844282A4 (https=)
JP (1) JP7490915B2 (https=)
KR (1) KR102879284B1 (https=)
CN (1) CN112639102B (https=)
AU (1) AU2019327913A1 (https=)
CA (1) CA3111087A1 (https=)
IL (1) IL281098A (https=)
SG (1) SG11202101773WA (https=)
TW (1) TW202024330A (https=)
WO (1) WO2020043152A1 (https=)

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CN107995913B (zh) 2015-05-18 2022-02-11 T细胞受体治疗公司 使用融合蛋白对tcr重编程的组合物和方法
WO2018140573A1 (en) * 2017-01-26 2018-08-02 Sangamo Therapeutics, Inc. B-cell engineering
EP3715368A1 (en) * 2019-03-28 2020-09-30 Albert-Ludwigs-Universität Freiburg Chimeric antigen receptors, vectors coding for such receptors and their use in the modification of t cells
KR20220078568A (ko) * 2019-08-14 2022-06-10 모드맵 테라퓨틱스 인코포레이티드 Lrp5 단백질에 결합하는 항체 및 사용 방법
CN110964750A (zh) * 2019-11-13 2020-04-07 沣潮医药科技（上海）有限公司 携带基因元件组合的嵌合抗原受体细胞文库、制备和筛选方法及用途
US12264190B2 (en) * 2020-04-24 2025-04-01 Astrazeneca Ab Compositions and methods of treating cancer with chimeric antigen receptors
US20240252641A1 (en) * 2020-05-05 2024-08-01 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using cd70 specific fusion proteins
GB202006820D0 (en) * 2020-05-07 2020-06-24 Autolus Ltd Cell
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