IL278976A - MUC16-specific chimeric antigen receptors and their use - Google Patents

MUC16-specific chimeric antigen receptors and their use

Info

Publication number
IL278976A
IL278976A IL278976A IL27897620A IL278976A IL 278976 A IL278976 A IL 278976A IL 278976 A IL278976 A IL 278976A IL 27897620 A IL27897620 A IL 27897620A IL 278976 A IL278976 A IL 278976A
Authority
IL
Israel
Prior art keywords
chimeric antigen
antigen receptors
specific chimeric
muc16
muc16 specific
Prior art date
Application number
IL278976A
Other languages
English (en)
Hebrew (he)
Inventor
Rutul R Shah
Helen Sabzevari
Original Assignee
Precigen Inc
Rutul R Shah
Helen Sabzevari
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Precigen Inc, Rutul R Shah, Helen Sabzevari filed Critical Precigen Inc
Publication of IL278976A publication Critical patent/IL278976A/en

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
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    • C07K16/3076—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3092—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
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IL278976A 2018-06-04 2020-11-25 MUC16-specific chimeric antigen receptors and their use IL278976A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862680297P 2018-06-04 2018-06-04
PCT/US2019/035384 WO2019236577A2 (en) 2018-06-04 2019-06-04 Muc16 specific chimeric antigen receptors and uses thereof

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IL278976A true IL278976A (en) 2021-01-31

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US (4) US11319380B2 (https=)
EP (1) EP3802615A4 (https=)
JP (3) JP2021525534A (https=)
KR (1) KR20210021493A (https=)
CN (2) CN121852427A (https=)
AU (1) AU2019282620B2 (https=)
CA (1) CA3101641A1 (https=)
IL (1) IL278976A (https=)
SG (1) SG11202011895VA (https=)
WO (1) WO2019236577A2 (https=)
ZA (3) ZA202008065B (https=)

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US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
EP3697438A4 (en) * 2017-10-18 2021-08-18 Intrexon Corporation POLYPEPTIDE COMPOSITIONS WITH SPACERS
SG11202104524YA (en) * 2018-11-01 2021-05-28 Gracell Biotechnologies Shanghai Co Ltd Compositions and methods for t cell engineering
CA3150224A1 (en) 2019-09-10 2021-03-18 Obsidian Therapeutics, Inc. Ca2 compositions and methods for tunable regulation
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