IL273297B2 - Gluconic acid derivatives for use in the treatment and/or prevention of bacterial infections - Google Patents
Gluconic acid derivatives for use in the treatment and/or prevention of bacterial infectionsInfo
- Publication number
- IL273297B2 IL273297B2 IL273297A IL27329720A IL273297B2 IL 273297 B2 IL273297 B2 IL 273297B2 IL 273297 A IL273297 A IL 273297A IL 27329720 A IL27329720 A IL 27329720A IL 273297 B2 IL273297 B2 IL 273297B2
- Authority
- IL
- Israel
- Prior art keywords
- compound
- vaginal
- use according
- infection
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/126—Acids containing more than four carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polyesters Or Polycarbonates (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17195192 | 2017-10-06 | ||
| PCT/EP2018/077129 WO2019068862A1 (en) | 2017-10-06 | 2018-10-05 | GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND / OR PREVENTION OF MICROBIAL INFECTIONS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL273297A IL273297A (en) | 2020-04-30 |
| IL273297B1 IL273297B1 (en) | 2024-02-01 |
| IL273297B2 true IL273297B2 (en) | 2024-06-01 |
Family
ID=60185986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL273297A IL273297B2 (en) | 2017-10-06 | 2018-10-05 | Gluconic acid derivatives for use in the treatment and/or prevention of bacterial infections |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US11612584B2 (enExample) |
| EP (1) | EP3691625B1 (enExample) |
| JP (1) | JP7424636B2 (enExample) |
| KR (1) | KR102650182B1 (enExample) |
| CN (1) | CN111182895B (enExample) |
| AU (1) | AU2018346361B2 (enExample) |
| BR (1) | BR112020006931A2 (enExample) |
| CA (1) | CA3078451A1 (enExample) |
| CL (1) | CL2020000859A1 (enExample) |
| EA (1) | EA202090750A1 (enExample) |
| ES (1) | ES3017694T3 (enExample) |
| HU (1) | HUE070746T2 (enExample) |
| IL (1) | IL273297B2 (enExample) |
| MX (1) | MX2020003660A (enExample) |
| MY (1) | MY205944A (enExample) |
| PH (1) | PH12020550222A1 (enExample) |
| PL (1) | PL3691625T3 (enExample) |
| SG (1) | SG11202002494WA (enExample) |
| UA (1) | UA126590C2 (enExample) |
| WO (1) | WO2019068862A1 (enExample) |
| ZA (1) | ZA202001605B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3017694T3 (en) | 2017-10-06 | 2025-05-13 | Gedea Biotech Ab | Gluconic acid derivatives for use in the treatment and/or prevention of microbial infections |
| MY208388A (en) | 2019-04-05 | 2025-05-06 | Gedea Biotech Ab | Vaginal tablet formulation |
| CN114751878B (zh) * | 2022-03-29 | 2023-06-16 | 青岛农业大学 | 一种BcTol1基因靶向剂及其应用 |
| WO2024261110A1 (en) * | 2023-06-22 | 2024-12-26 | Gedea Biotech Ab | Compositions for promoting growth of lactobacillus crispatus |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060172007A1 (en) * | 2001-05-01 | 2006-08-03 | Nawaz Ahmad | Compositions and methods for reducing vaginal pH |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1278868B1 (it) | 1995-10-27 | 1997-11-28 | Sanitaria Scaligera Spa | Metodo per l'ottenimento di un materiale riassorbibile atto ad essere utilizzato come elemento di rivestimento per la prevenzione di |
| AUPP839499A0 (en) | 1999-01-29 | 1999-02-25 | Australian National University, The | A method for controlling plant pathogens, and agents useful for same |
| JP3745612B2 (ja) | 2000-10-31 | 2006-02-15 | 西川ゴム工業株式会社 | ポリヒドロキシカルボン酸の製造方法 |
| US20030017207A1 (en) | 2001-05-01 | 2003-01-23 | Lin Shun Y. | Compositions and methods for treating vulvovaginitis and vaginosis |
| US20060105008A1 (en) | 2002-03-28 | 2006-05-18 | Nawaz Ahmad | Compositions and methods for reducing vaginal pH |
| CA2487270C (en) | 2002-06-21 | 2010-10-26 | The Procter & Gamble Company | Antimicrobial compositions, products and methods employing same |
| US7569530B1 (en) | 2003-06-20 | 2009-08-04 | The Procter & Gamble Company | Antimicrobial compositions, products and methods employing same |
| US7547454B2 (en) * | 2002-11-07 | 2009-06-16 | Shyam K Gupta | Hydroxy acid complexes for antiaging and skin renovation |
| US20040126369A1 (en) * | 2002-12-30 | 2004-07-01 | Richard Payne | Delivery of peroxide-generating enzymes to the vaginal tract |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| US20050260243A1 (en) * | 2004-04-26 | 2005-11-24 | The Procter & Gamble Company | Method of treating microbial plant diseases |
| US20050271711A1 (en) | 2004-04-26 | 2005-12-08 | The Procter & Gamble Company | Therapeutic antimicrobial compositions and methods |
| AU2006209263A1 (en) | 2005-09-12 | 2007-03-29 | Mcneil-Ppc, Inc. | Anhydrous composition containing an acid-acid buffer system |
| US20070059278A1 (en) | 2005-09-12 | 2007-03-15 | Nawaz Ahmad | Anhydrous composition containing an acid-acid buffer system |
| US20080058421A1 (en) * | 2006-09-05 | 2008-03-06 | John Alex Lopes | Compositions for cleaning and disinfecting nasal tract and sinus cavity |
| WO2008108834A2 (en) * | 2006-11-09 | 2008-09-12 | Northwestern University | Inhibitors of the mevalonate pathway of streptococcus pneumoniae |
| JP2008283893A (ja) * | 2007-05-16 | 2008-11-27 | Sumitomo Chemical Co Ltd | 家禽用コクシジウム感染抑制剤及びそれを用いたコクシジウム感染抑制方法 |
| US20100285095A1 (en) * | 2009-05-05 | 2010-11-11 | Kimberly Ann Nemeth | Hygiene Article Having Calcium Sugar Acid Salt |
| CN102070774B (zh) | 2010-11-25 | 2012-08-22 | 华南师范大学 | 单糖或其糖醇与乳酸的共聚物的制备方法 |
| MX2013012745A (es) | 2011-05-02 | 2014-12-05 | Aptalis Pharmatech Inc | Composiciones en forma de comprmido de disolución rápida para administración vaginal. |
| MY172685A (en) | 2013-11-08 | 2019-12-10 | Suzhou Osel Bio Pharm Co Ltd | A lactobacillus crispatus and application thereof |
| DK178786B1 (en) * | 2015-03-11 | 2017-02-06 | Dantrace-Danfeed Ivs | Use of zinc and copper gluconate in the treatment of methicillin-resistant staphylococcus aureus |
| DK3439633T3 (da) * | 2016-04-06 | 2021-12-20 | Gedea Biotech Ab | Glucono delta-lacton til behandling af vaginale svampeinfektioner |
| JP7219712B2 (ja) | 2016-10-13 | 2023-02-08 | キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド | 膣送達のための凍結乾燥医薬組成物 |
| KR101841976B1 (ko) | 2017-06-07 | 2018-05-14 | 조영진 | 식물 추출물을 포함하는 항진균 및 항균 조성물 |
| ES3017694T3 (en) | 2017-10-06 | 2025-05-13 | Gedea Biotech Ab | Gluconic acid derivatives for use in the treatment and/or prevention of microbial infections |
| MY208388A (en) | 2019-04-05 | 2025-05-06 | Gedea Biotech Ab | Vaginal tablet formulation |
-
2018
- 2018-10-05 ES ES18788687T patent/ES3017694T3/es active Active
- 2018-10-05 EA EA202090750A patent/EA202090750A1/ru unknown
- 2018-10-05 KR KR1020207010202A patent/KR102650182B1/ko active Active
- 2018-10-05 AU AU2018346361A patent/AU2018346361B2/en active Active
- 2018-10-05 MX MX2020003660A patent/MX2020003660A/es unknown
- 2018-10-05 WO PCT/EP2018/077129 patent/WO2019068862A1/en not_active Ceased
- 2018-10-05 MY MYPI2020001657A patent/MY205944A/en unknown
- 2018-10-05 US US16/753,899 patent/US11612584B2/en active Active
- 2018-10-05 UA UAA202002422A patent/UA126590C2/uk unknown
- 2018-10-05 CA CA3078451A patent/CA3078451A1/en active Pending
- 2018-10-05 PL PL18788687.4T patent/PL3691625T3/pl unknown
- 2018-10-05 SG SG11202002494WA patent/SG11202002494WA/en unknown
- 2018-10-05 JP JP2020519028A patent/JP7424636B2/ja active Active
- 2018-10-05 EP EP18788687.4A patent/EP3691625B1/en active Active
- 2018-10-05 BR BR112020006931-0A patent/BR112020006931A2/pt unknown
- 2018-10-05 HU HUE18788687A patent/HUE070746T2/hu unknown
- 2018-10-05 CN CN201880065162.XA patent/CN111182895B/zh active Active
- 2018-10-05 IL IL273297A patent/IL273297B2/en unknown
-
2020
- 2020-03-13 ZA ZA2020/01605A patent/ZA202001605B/en unknown
- 2020-03-31 CL CL2020000859A patent/CL2020000859A1/es unknown
- 2020-04-06 PH PH12020550222A patent/PH12020550222A1/en unknown
-
2023
- 2023-02-02 US US18/163,321 patent/US12226396B2/en active Active
-
2025
- 2025-01-08 US US19/013,187 patent/US20250144070A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060172007A1 (en) * | 2001-05-01 | 2006-08-03 | Nawaz Ahmad | Compositions and methods for reducing vaginal pH |
Non-Patent Citations (1)
| Title |
|---|
| OWEN, M. K., & CLENNEY, T. L.,, MANAGEMENT OF VAGINITIS, 1 December 2004 (2004-12-01) * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR102650182B1 (ko) | 2024-03-21 |
| US20200253925A1 (en) | 2020-08-13 |
| SG11202002494WA (en) | 2020-04-29 |
| PH12020550222A1 (en) | 2021-02-15 |
| MX2020003660A (es) | 2020-08-03 |
| BR112020006931A2 (pt) | 2020-10-06 |
| UA126590C2 (uk) | 2022-11-02 |
| CA3078451A1 (en) | 2019-04-11 |
| PL3691625T3 (pl) | 2025-05-12 |
| JP2020536862A (ja) | 2020-12-17 |
| ES3017694T3 (en) | 2025-05-13 |
| EP3691625A1 (en) | 2020-08-12 |
| CN111182895A (zh) | 2020-05-19 |
| IL273297B1 (en) | 2024-02-01 |
| CL2020000859A1 (es) | 2020-10-02 |
| AU2018346361B2 (en) | 2024-07-25 |
| US11612584B2 (en) | 2023-03-28 |
| ZA202001605B (en) | 2023-12-20 |
| AU2018346361A1 (en) | 2020-05-14 |
| JP7424636B2 (ja) | 2024-01-30 |
| US12226396B2 (en) | 2025-02-18 |
| US20230181523A1 (en) | 2023-06-15 |
| EP3691625B1 (en) | 2025-02-19 |
| HUE070746T2 (hu) | 2025-07-28 |
| MY205944A (en) | 2024-11-21 |
| US20250144070A1 (en) | 2025-05-08 |
| EP3691625C0 (en) | 2025-02-19 |
| WO2019068862A1 (en) | 2019-04-11 |
| EA202090750A1 (ru) | 2020-11-11 |
| CN111182895B (zh) | 2024-05-14 |
| KR20200060413A (ko) | 2020-05-29 |
| IL273297A (en) | 2020-04-30 |
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