IL273297B2 - Gluconic acid derivatives for use in the treatment and/or prevention of bacterial infections - Google Patents

Gluconic acid derivatives for use in the treatment and/or prevention of bacterial infections

Info

Publication number
IL273297B2
IL273297B2 IL273297A IL27329720A IL273297B2 IL 273297 B2 IL273297 B2 IL 273297B2 IL 273297 A IL273297 A IL 273297A IL 27329720 A IL27329720 A IL 27329720A IL 273297 B2 IL273297 B2 IL 273297B2
Authority
IL
Israel
Prior art keywords
compound
vaginal
use according
infection
pharmaceutical composition
Prior art date
Application number
IL273297A
Other languages
English (en)
Hebrew (he)
Other versions
IL273297B1 (en
IL273297A (en
Original Assignee
Gedea Biotech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gedea Biotech Ab filed Critical Gedea Biotech Ab
Publication of IL273297A publication Critical patent/IL273297A/en
Publication of IL273297B1 publication Critical patent/IL273297B1/en
Publication of IL273297B2 publication Critical patent/IL273297B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL273297A 2017-10-06 2018-10-05 Gluconic acid derivatives for use in the treatment and/or prevention of bacterial infections IL273297B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17195192 2017-10-06
PCT/EP2018/077129 WO2019068862A1 (en) 2017-10-06 2018-10-05 GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND / OR PREVENTION OF MICROBIAL INFECTIONS

Publications (3)

Publication Number Publication Date
IL273297A IL273297A (en) 2020-04-30
IL273297B1 IL273297B1 (en) 2024-02-01
IL273297B2 true IL273297B2 (en) 2024-06-01

Family

ID=60185986

Family Applications (1)

Application Number Title Priority Date Filing Date
IL273297A IL273297B2 (en) 2017-10-06 2018-10-05 Gluconic acid derivatives for use in the treatment and/or prevention of bacterial infections

Country Status (21)

Country Link
US (3) US11612584B2 (enExample)
EP (1) EP3691625B1 (enExample)
JP (1) JP7424636B2 (enExample)
KR (1) KR102650182B1 (enExample)
CN (1) CN111182895B (enExample)
AU (1) AU2018346361B2 (enExample)
BR (1) BR112020006931A2 (enExample)
CA (1) CA3078451A1 (enExample)
CL (1) CL2020000859A1 (enExample)
EA (1) EA202090750A1 (enExample)
ES (1) ES3017694T3 (enExample)
HU (1) HUE070746T2 (enExample)
IL (1) IL273297B2 (enExample)
MX (1) MX2020003660A (enExample)
MY (1) MY205944A (enExample)
PH (1) PH12020550222A1 (enExample)
PL (1) PL3691625T3 (enExample)
SG (1) SG11202002494WA (enExample)
UA (1) UA126590C2 (enExample)
WO (1) WO2019068862A1 (enExample)
ZA (1) ZA202001605B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019068862A1 (en) 2017-10-06 2019-04-11 Gedea Biotech Ab GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND / OR PREVENTION OF MICROBIAL INFECTIONS
MA56011A (fr) 2019-04-05 2022-04-06 Gedea Biotech Ab Formulation de comprimé vaginal
CN114751878B (zh) * 2022-03-29 2023-06-16 青岛农业大学 一种BcTol1基因靶向剂及其应用
EP4731203A1 (en) * 2023-06-22 2026-04-29 Gedea Biotech AB Compositions for promoting growth of lactobacillus crispatus

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060172007A1 (en) * 2001-05-01 2006-08-03 Nawaz Ahmad Compositions and methods for reducing vaginal pH

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Publication number Priority date Publication date Assignee Title
IT1278868B1 (it) 1995-10-27 1997-11-28 Sanitaria Scaligera Spa Metodo per l'ottenimento di un materiale riassorbibile atto ad essere utilizzato come elemento di rivestimento per la prevenzione di
AUPP839499A0 (en) 1999-01-29 1999-02-25 Australian National University, The A method for controlling plant pathogens, and agents useful for same
JP3745612B2 (ja) 2000-10-31 2006-02-15 西川ゴム工業株式会社 ポリヒドロキシカルボン酸の製造方法
US20030017207A1 (en) * 2001-05-01 2003-01-23 Lin Shun Y. Compositions and methods for treating vulvovaginitis and vaginosis
US20060105008A1 (en) * 2002-03-28 2006-05-18 Nawaz Ahmad Compositions and methods for reducing vaginal pH
US7569530B1 (en) 2003-06-20 2009-08-04 The Procter & Gamble Company Antimicrobial compositions, products and methods employing same
CA2487270C (en) 2002-06-21 2010-10-26 The Procter & Gamble Company Antimicrobial compositions, products and methods employing same
US7547454B2 (en) * 2002-11-07 2009-06-16 Shyam K Gupta Hydroxy acid complexes for antiaging and skin renovation
US20040126369A1 (en) * 2002-12-30 2004-07-01 Richard Payne Delivery of peroxide-generating enzymes to the vaginal tract
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US20050260243A1 (en) * 2004-04-26 2005-11-24 The Procter & Gamble Company Method of treating microbial plant diseases
US20050271711A1 (en) 2004-04-26 2005-12-08 The Procter & Gamble Company Therapeutic antimicrobial compositions and methods
AU2006209263A1 (en) 2005-09-12 2007-03-29 Mcneil-Ppc, Inc. Anhydrous composition containing an acid-acid buffer system
US20070059278A1 (en) 2005-09-12 2007-03-15 Nawaz Ahmad Anhydrous composition containing an acid-acid buffer system
US20080058421A1 (en) 2006-09-05 2008-03-06 John Alex Lopes Compositions for cleaning and disinfecting nasal tract and sinus cavity
WO2008108834A2 (en) * 2006-11-09 2008-09-12 Northwestern University Inhibitors of the mevalonate pathway of streptococcus pneumoniae
JP2008283893A (ja) * 2007-05-16 2008-11-27 Sumitomo Chemical Co Ltd 家禽用コクシジウム感染抑制剤及びそれを用いたコクシジウム感染抑制方法
US20100285095A1 (en) * 2009-05-05 2010-11-11 Kimberly Ann Nemeth Hygiene Article Having Calcium Sugar Acid Salt
CN102070774B (zh) 2010-11-25 2012-08-22 华南师范大学 单糖或其糖醇与乳酸的共聚物的制备方法
EP2704694A4 (en) 2011-05-02 2014-11-19 Aptalis Pharmatech Inc RAPID DISSOLUTION TABLET COMPOSITIONS FOR VAGINAL DELIVERY
US9937214B2 (en) 2013-11-08 2018-04-10 Suzhou Osel Bio-Pharm Co., Ltd. Lactobacillus crispatus and application thereof
DK178786B1 (en) * 2015-03-11 2017-02-06 Dantrace-Danfeed Ivs Use of zinc and copper gluconate in the treatment of methicillin-resistant staphylococcus aureus
MX382396B (es) * 2016-04-06 2025-03-13 Gedea Biotech Ab Glucono delta-lactona para el tratamiento de infecciones fúngicas vaginales.
CA3040422A1 (en) 2016-10-13 2018-04-19 Catalent U.K. Swindon Zydis Limited Lyophilized pharmaceutical compositions for vaginal delivery
KR101841976B1 (ko) 2017-06-07 2018-05-14 조영진 식물 추출물을 포함하는 항진균 및 항균 조성물
WO2019068862A1 (en) 2017-10-06 2019-04-11 Gedea Biotech Ab GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND / OR PREVENTION OF MICROBIAL INFECTIONS
MA56011A (fr) 2019-04-05 2022-04-06 Gedea Biotech Ab Formulation de comprimé vaginal

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060172007A1 (en) * 2001-05-01 2006-08-03 Nawaz Ahmad Compositions and methods for reducing vaginal pH

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
OWEN, M. K., & CLENNEY, T. L.,, MANAGEMENT OF VAGINITIS, 1 December 2004 (2004-12-01) *

Also Published As

Publication number Publication date
ZA202001605B (en) 2023-12-20
IL273297B1 (en) 2024-02-01
US11612584B2 (en) 2023-03-28
UA126590C2 (uk) 2022-11-02
EP3691625C0 (en) 2025-02-19
JP7424636B2 (ja) 2024-01-30
PL3691625T3 (pl) 2025-05-12
AU2018346361B2 (en) 2024-07-25
IL273297A (en) 2020-04-30
BR112020006931A2 (pt) 2020-10-06
EP3691625B1 (en) 2025-02-19
HUE070746T2 (hu) 2025-07-28
ES3017694T3 (en) 2025-05-13
EP3691625A1 (en) 2020-08-12
WO2019068862A1 (en) 2019-04-11
US20200253925A1 (en) 2020-08-13
AU2018346361A1 (en) 2020-05-14
US12226396B2 (en) 2025-02-18
US20230181523A1 (en) 2023-06-15
CL2020000859A1 (es) 2020-10-02
PH12020550222A1 (en) 2021-02-15
MX2020003660A (es) 2020-08-03
JP2020536862A (ja) 2020-12-17
SG11202002494WA (en) 2020-04-29
CN111182895B (zh) 2024-05-14
KR102650182B1 (ko) 2024-03-21
CN111182895A (zh) 2020-05-19
CA3078451A1 (en) 2019-04-11
EA202090750A1 (ru) 2020-11-11
MY205944A (en) 2024-11-21
US20250144070A1 (en) 2025-05-08
KR20200060413A (ko) 2020-05-29

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