KR102650182B1 - 미생물 감염의 치료 및/또는 예방에서 사용하기 위한 글루콘산 유도체 - Google Patents

미생물 감염의 치료 및/또는 예방에서 사용하기 위한 글루콘산 유도체 Download PDF

Info

Publication number
KR102650182B1
KR102650182B1 KR1020207010202A KR20207010202A KR102650182B1 KR 102650182 B1 KR102650182 B1 KR 102650182B1 KR 1020207010202 A KR1020207010202 A KR 1020207010202A KR 20207010202 A KR20207010202 A KR 20207010202A KR 102650182 B1 KR102650182 B1 KR 102650182B1
Authority
KR
South Korea
Prior art keywords
delete delete
infection
vaginal
formula
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020207010202A
Other languages
English (en)
Korean (ko)
Other versions
KR20200060413A (ko
Inventor
울프 엘러빅
올로브 스터너
헬레나 스트레벤스
소피 매너
Original Assignee
게데아 바이오테크 아베
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 게데아 바이오테크 아베 filed Critical 게데아 바이오테크 아베
Publication of KR20200060413A publication Critical patent/KR20200060413A/ko
Application granted granted Critical
Publication of KR102650182B1 publication Critical patent/KR102650182B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020207010202A 2017-10-06 2018-10-05 미생물 감염의 치료 및/또는 예방에서 사용하기 위한 글루콘산 유도체 Active KR102650182B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17195192.4 2017-10-06
EP17195192 2017-10-06
PCT/EP2018/077129 WO2019068862A1 (en) 2017-10-06 2018-10-05 GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND / OR PREVENTION OF MICROBIAL INFECTIONS

Publications (2)

Publication Number Publication Date
KR20200060413A KR20200060413A (ko) 2020-05-29
KR102650182B1 true KR102650182B1 (ko) 2024-03-21

Family

ID=60185986

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207010202A Active KR102650182B1 (ko) 2017-10-06 2018-10-05 미생물 감염의 치료 및/또는 예방에서 사용하기 위한 글루콘산 유도체

Country Status (21)

Country Link
US (3) US11612584B2 (enExample)
EP (1) EP3691625B1 (enExample)
JP (1) JP7424636B2 (enExample)
KR (1) KR102650182B1 (enExample)
CN (1) CN111182895B (enExample)
AU (1) AU2018346361B2 (enExample)
BR (1) BR112020006931A2 (enExample)
CA (1) CA3078451A1 (enExample)
CL (1) CL2020000859A1 (enExample)
EA (1) EA202090750A1 (enExample)
ES (1) ES3017694T3 (enExample)
HU (1) HUE070746T2 (enExample)
IL (1) IL273297B2 (enExample)
MX (1) MX2020003660A (enExample)
MY (1) MY205944A (enExample)
PH (1) PH12020550222A1 (enExample)
PL (1) PL3691625T3 (enExample)
SG (1) SG11202002494WA (enExample)
UA (1) UA126590C2 (enExample)
WO (1) WO2019068862A1 (enExample)
ZA (1) ZA202001605B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019068862A1 (en) 2017-10-06 2019-04-11 Gedea Biotech Ab GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND / OR PREVENTION OF MICROBIAL INFECTIONS
MA56011A (fr) 2019-04-05 2022-04-06 Gedea Biotech Ab Formulation de comprimé vaginal
CN114751878B (zh) * 2022-03-29 2023-06-16 青岛农业大学 一种BcTol1基因靶向剂及其应用
EP4731203A1 (en) * 2023-06-22 2026-04-29 Gedea Biotech AB Compositions for promoting growth of lactobacillus crispatus

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1278868B1 (it) 1995-10-27 1997-11-28 Sanitaria Scaligera Spa Metodo per l'ottenimento di un materiale riassorbibile atto ad essere utilizzato come elemento di rivestimento per la prevenzione di
AUPP839499A0 (en) 1999-01-29 1999-02-25 Australian National University, The A method for controlling plant pathogens, and agents useful for same
JP3745612B2 (ja) 2000-10-31 2006-02-15 西川ゴム工業株式会社 ポリヒドロキシカルボン酸の製造方法
US20060172007A1 (en) * 2001-05-01 2006-08-03 Nawaz Ahmad Compositions and methods for reducing vaginal pH
US20030017207A1 (en) * 2001-05-01 2003-01-23 Lin Shun Y. Compositions and methods for treating vulvovaginitis and vaginosis
US20060105008A1 (en) * 2002-03-28 2006-05-18 Nawaz Ahmad Compositions and methods for reducing vaginal pH
US7569530B1 (en) 2003-06-20 2009-08-04 The Procter & Gamble Company Antimicrobial compositions, products and methods employing same
CA2487270C (en) 2002-06-21 2010-10-26 The Procter & Gamble Company Antimicrobial compositions, products and methods employing same
US7547454B2 (en) * 2002-11-07 2009-06-16 Shyam K Gupta Hydroxy acid complexes for antiaging and skin renovation
US20040126369A1 (en) * 2002-12-30 2004-07-01 Richard Payne Delivery of peroxide-generating enzymes to the vaginal tract
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US20050260243A1 (en) * 2004-04-26 2005-11-24 The Procter & Gamble Company Method of treating microbial plant diseases
US20050271711A1 (en) 2004-04-26 2005-12-08 The Procter & Gamble Company Therapeutic antimicrobial compositions and methods
AU2006209263A1 (en) 2005-09-12 2007-03-29 Mcneil-Ppc, Inc. Anhydrous composition containing an acid-acid buffer system
US20070059278A1 (en) 2005-09-12 2007-03-15 Nawaz Ahmad Anhydrous composition containing an acid-acid buffer system
US20080058421A1 (en) 2006-09-05 2008-03-06 John Alex Lopes Compositions for cleaning and disinfecting nasal tract and sinus cavity
WO2008108834A2 (en) * 2006-11-09 2008-09-12 Northwestern University Inhibitors of the mevalonate pathway of streptococcus pneumoniae
JP2008283893A (ja) * 2007-05-16 2008-11-27 Sumitomo Chemical Co Ltd 家禽用コクシジウム感染抑制剤及びそれを用いたコクシジウム感染抑制方法
US20100285095A1 (en) * 2009-05-05 2010-11-11 Kimberly Ann Nemeth Hygiene Article Having Calcium Sugar Acid Salt
CN102070774B (zh) 2010-11-25 2012-08-22 华南师范大学 单糖或其糖醇与乳酸的共聚物的制备方法
EP2704694A4 (en) 2011-05-02 2014-11-19 Aptalis Pharmatech Inc RAPID DISSOLUTION TABLET COMPOSITIONS FOR VAGINAL DELIVERY
US9937214B2 (en) 2013-11-08 2018-04-10 Suzhou Osel Bio-Pharm Co., Ltd. Lactobacillus crispatus and application thereof
DK178786B1 (en) * 2015-03-11 2017-02-06 Dantrace-Danfeed Ivs Use of zinc and copper gluconate in the treatment of methicillin-resistant staphylococcus aureus
MX382396B (es) * 2016-04-06 2025-03-13 Gedea Biotech Ab Glucono delta-lactona para el tratamiento de infecciones fúngicas vaginales.
CA3040422A1 (en) 2016-10-13 2018-04-19 Catalent U.K. Swindon Zydis Limited Lyophilized pharmaceutical compositions for vaginal delivery
KR101841976B1 (ko) 2017-06-07 2018-05-14 조영진 식물 추출물을 포함하는 항진균 및 항균 조성물
WO2019068862A1 (en) 2017-10-06 2019-04-11 Gedea Biotech Ab GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND / OR PREVENTION OF MICROBIAL INFECTIONS
MA56011A (fr) 2019-04-05 2022-04-06 Gedea Biotech Ab Formulation de comprimé vaginal

Also Published As

Publication number Publication date
ZA202001605B (en) 2023-12-20
IL273297B1 (en) 2024-02-01
US11612584B2 (en) 2023-03-28
UA126590C2 (uk) 2022-11-02
EP3691625C0 (en) 2025-02-19
JP7424636B2 (ja) 2024-01-30
PL3691625T3 (pl) 2025-05-12
AU2018346361B2 (en) 2024-07-25
IL273297A (en) 2020-04-30
BR112020006931A2 (pt) 2020-10-06
EP3691625B1 (en) 2025-02-19
HUE070746T2 (hu) 2025-07-28
ES3017694T3 (en) 2025-05-13
EP3691625A1 (en) 2020-08-12
WO2019068862A1 (en) 2019-04-11
US20200253925A1 (en) 2020-08-13
AU2018346361A1 (en) 2020-05-14
US12226396B2 (en) 2025-02-18
US20230181523A1 (en) 2023-06-15
CL2020000859A1 (es) 2020-10-02
PH12020550222A1 (en) 2021-02-15
MX2020003660A (es) 2020-08-03
IL273297B2 (en) 2024-06-01
JP2020536862A (ja) 2020-12-17
SG11202002494WA (en) 2020-04-29
CN111182895B (zh) 2024-05-14
CN111182895A (zh) 2020-05-19
CA3078451A1 (en) 2019-04-11
EA202090750A1 (ru) 2020-11-11
MY205944A (en) 2024-11-21
US20250144070A1 (en) 2025-05-08
KR20200060413A (ko) 2020-05-29

Similar Documents

Publication Publication Date Title
US12226396B2 (en) Gluconic acid derivatives for use in the treatment and/or prevention of microbial infections
CA2819632C (en) Vaginal composition based on alkyl polyglucosides
CN105232526A (zh) 含儿茶素的药物在制备抑菌药物中的用途
CZ298270B6 (cs) Farmaceutické kompozice tizoxanidu a/nebo nitazoxanidu
WO2021006317A1 (ja) プロトテカ症の新規治療剤
JP6967785B2 (ja) 膣真菌感染症の治療のためのグルコノデルタ−ラクトン
KR20150002676A (ko) 질 염증에서의 병원성 질 균막의 예방 및 치료를 위한 양쪽성 계면활성제의 용도
CN112236163B (zh) 使用协同量的硼酸增强缩酚酸肽抗生素的抗菌作用
RU2436570C1 (ru) Способ лечения эндометритов бактериально-микозной этиологии у коров
MX2007011885A (es) Un metodo para prevenir y/o tratar infecciones vaginales y de vulva.
HK40029669B (en) Gluconic acid derivatives for use in the treatment and/or prevention of microbial infections
HK40029669A (en) Gluconic acid derivatives for use in the treatment and/or prevention of microbial infections
JP2025151411A (ja) 細菌性膣症の抑制剤、細菌性膣症関連細菌のオートインデューサー－２阻害剤、細菌性膣症関連細菌のバイオフィルム形成の抑制剤、細菌性膣症関連細菌に対する抗菌薬抗菌力の増強剤、及び当該抗菌力の増強方法
JP2019521134A (ja) 性感染症用組成物
WO2024262189A1 (ja) 細菌の増殖抑制剤、それを含む化粧品、医薬部外品、及び医薬組成物、並びに細菌の増殖抑制方法

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20200408

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20210930

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20230731

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20240227

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20240318

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20240319

End annual number: 3

Start annual number: 1

PG1601 Publication of registration