IL268197A - CSF1R-based chimeric proteins - Google Patents
CSF1R-based chimeric proteinsInfo
- Publication number
- IL268197A IL268197A IL268197A IL26819719A IL268197A IL 268197 A IL268197 A IL 268197A IL 268197 A IL268197 A IL 268197A IL 26819719 A IL26819719 A IL 26819719A IL 268197 A IL268197 A IL 268197A
- Authority
- IL
- Israel
- Prior art keywords
- csf1r
- chimeric proteins
- based chimeric
- proteins
- chimeric
- Prior art date
Links
- 101150053778 CSF1R gene Proteins 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7153—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for colony-stimulating factors [CSF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C07K5/06095—Arg-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762463997P | 2017-02-27 | 2017-02-27 | |
| PCT/US2018/020039 WO2018157164A1 (en) | 2017-02-27 | 2018-02-27 | Csf1r-based chimeric proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL268197A true IL268197A (en) | 2019-09-26 |
Family
ID=63253352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL268197A IL268197A (en) | 2017-02-27 | 2019-07-21 | CSF1R-based chimeric proteins |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US11267856B2 (enExample) |
| EP (1) | EP3585409A4 (enExample) |
| JP (2) | JP7121029B2 (enExample) |
| KR (1) | KR20190124247A (enExample) |
| CN (1) | CN110381974A (enExample) |
| AU (1) | AU2018223822A1 (enExample) |
| BR (1) | BR112019017713A2 (enExample) |
| CA (1) | CA3054132A1 (enExample) |
| IL (1) | IL268197A (enExample) |
| MX (1) | MX2019010173A (enExample) |
| PH (1) | PH12019501534A1 (enExample) |
| SA (1) | SA519402522B1 (enExample) |
| SG (1) | SG11201906464UA (enExample) |
| WO (1) | WO2018157164A1 (enExample) |
| ZA (1) | ZA201906235B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3585409A4 (en) | 2017-02-27 | 2020-12-02 | Shattuck Labs, Inc. | CHEMERICAL PROTEINS BASED ON CSF1R |
| CA3131259A1 (en) * | 2019-02-28 | 2020-09-03 | Shattuck Labs, Inc. | Combination therapies |
| JP2022537066A (ja) * | 2019-06-21 | 2022-08-23 | シャタック ラボ，インコーポレイテッド | キメラタンパク質を発現するｔ細胞 |
| CN111068054B (zh) * | 2019-11-06 | 2022-02-11 | 浙江大学医学院附属第一医院 | 以csf1r作为药物靶点治疗肿瘤的药剂及其制备方法 |
| US20230203170A1 (en) * | 2019-12-24 | 2023-06-29 | Adagene (Suzhou) Limited | Anti-CSF1R Molecules and Use Thereof |
| KR102671409B1 (ko) * | 2021-03-02 | 2024-05-31 | 진화섭 | Cd30을 발현하는 세포에 독성을 나타내는 재조합 단백질 및 이를 유효성분으로 포함하는 암의 치료용 약학적 조성물 |
| KR20230012129A (ko) * | 2021-07-14 | 2023-01-26 | 주식회사 이뮤노로지컬디자이닝랩 | Cd30에 특이적으로 결합하는 키메릭 항원 수용체 및 이의 용도 |
| WO2024123812A1 (en) | 2022-12-05 | 2024-06-13 | Shattuck Labs, Inc. | Fusion proteins for the treatment of cardiometabolic diseases |
Family Cites Families (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5844095A (en) | 1991-06-27 | 1998-12-01 | Bristol-Myers Squibb Company | CTLA4 Ig fusion proteins |
| WO1993008207A1 (en) * | 1991-10-25 | 1993-04-29 | Immunex Corporation | Novel cytokine |
| AU2926401A (en) | 2000-01-03 | 2001-07-16 | Tr Associates, L.L.C. | Novel chimeric proteins and methods for using the same |
| US20110041190A1 (en) | 2002-10-31 | 2011-02-17 | Tykocinski Mark L | Novel chimeric proteins |
| US7696168B2 (en) | 2000-04-21 | 2010-04-13 | Tufts Medical Center, Inc. | G protein coupled receptor agonists and antagonists and methods of activating and inhibiting G protein coupled receptors using the same |
| DK1682583T3 (da) | 2003-11-13 | 2012-05-07 | Hanmi Holdings Co Ltd | Proteinkompleksdannelse under anvendelse af immunoglobulinfragment samt fremgangsmåde til fremstilling deraf |
| JP2006345852A (ja) | 2005-06-16 | 2006-12-28 | Virxsys Corp | 抗体複合体 |
| CA2652570A1 (en) | 2006-05-15 | 2007-11-22 | Viral Logic Systems Technology Corp. | Cd47 related compositions and methods for treating immunological diseases and disorders |
| AU2007257692B2 (en) | 2006-06-12 | 2013-11-14 | Aptevo Research And Development Llc | Single-chain multivalent binding proteins with effector function |
| WO2008061377A1 (en) | 2006-11-22 | 2008-05-29 | Centre Hospitalier De L'universite De Montreal | Novel receptor for cd40l and uses thereof |
| DK3056515T4 (da) | 2008-01-15 | 2025-10-20 | Univ Leland Stanford Junior | Fremgangsmåde til at manipulere fagocytose medieret af cd47 |
| EP2262531A1 (en) | 2008-03-08 | 2010-12-22 | Immungene, Inc. | Engineered fusion molecules immunotherapy in cancer and inflammatory diseases |
| EP2111869A1 (en) | 2008-04-23 | 2009-10-28 | Stichting Sanquin Bloedvoorziening | Compositions and methods to enhance the immune system |
| WO2010005519A1 (en) | 2008-06-30 | 2010-01-14 | University Of Pennsylvania | Fn14/trail fusion proteins |
| NZ590667A (en) | 2008-07-02 | 2013-01-25 | Emergent Product Dev Seattle | Tgf-b antagonist multi-target binding proteins |
| WO2010062401A2 (en) * | 2008-11-26 | 2010-06-03 | Five Prime Therapeutics, Inc. | Treatment of osteolytic disorders and cancer using csf1r extracellular domain fusion molecules |
| WO2010062399A2 (en) * | 2008-11-26 | 2010-06-03 | Five Prime Therapeutics, Inc. | Csf1r extracellular domain fusion molecules and treatments using same |
| CA2747678A1 (en) | 2008-12-19 | 2010-06-24 | Novartis Ag | Soluble polypeptides for use in treating autoimmune and inflammatory disorders |
| CN103641918A (zh) | 2009-03-13 | 2014-03-19 | 宾夕法尼亚大学董事会 | Ox40/trail融合蛋白 |
| IL323000A (en) | 2010-03-05 | 2025-10-01 | Univ Johns Hopkins | Compositions and methods for antibodies and fusion proteins targeted for immune modulation |
| CN103153332A (zh) | 2010-09-28 | 2013-06-12 | 卡尔医疗有限公司 | 用于治疗血液恶性肿瘤的组合物和方法 |
| WO2012062218A1 (en) | 2010-11-11 | 2012-05-18 | The University Of Hong Kong | Soluble pd-1 variants, fusion constructs, and uses thereof |
| SI2697257T1 (sl) * | 2011-04-13 | 2017-02-28 | Bristol-Myers Squibb Company | FC fuzijski proteini, ki vsebujejo nove linkerje ali razmestitve |
| WO2012162565A2 (en) | 2011-05-25 | 2012-11-29 | Cel-Sci Corporation | Method for inducing an immune response for treatment of cancer and autoimmune diseases or conditions |
| CN102850458B (zh) | 2011-06-28 | 2014-10-01 | 华博生物医药技术（上海）有限公司 | 新型重组双功能融合蛋白及其制法和用途 |
| EA201490364A1 (ru) | 2011-07-29 | 2014-08-29 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Костимулирующие рецепторы-переключатели |
| ES2740358T3 (es) | 2012-02-06 | 2020-02-05 | Providence Health & Services Oregon | Método de supervisión del tratamiento del cáncer con agonistas de OX40 |
| ES2938182T3 (es) | 2012-04-30 | 2023-04-05 | Biocon Ltd | Proteínas de fusión dirigidas/inmunomoduladoras y métodos de preparación de las mismas |
| ES2924722T3 (es) | 2012-05-18 | 2022-10-10 | Aptevo Res & Development Llc | Unión de inmunofusión de scFv biespecífico (BIf) a CD123 y CD3 |
| CN112587658A (zh) | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| CN107759690A (zh) * | 2012-08-31 | 2018-03-06 | 戊瑞治疗有限公司 | 用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法 |
| DK2931752T3 (da) | 2012-12-17 | 2019-11-18 | Trillium Therapeutics Inc | Behandling af cd47+ sygdomsceller med sirp-alpha-fc-fusioner |
| EP2941438A1 (en) | 2013-01-01 | 2015-11-11 | Kahr Medical Ltd. | Stable form of signal converting protein fusion proteins, and methods of use and preparation thereof |
| US20140242077A1 (en) | 2013-01-23 | 2014-08-28 | Abbvie, Inc. | Methods and compositions for modulating an immune response |
| EP2951199A4 (en) | 2013-01-31 | 2016-07-20 | Univ Jefferson | Fusion proteins for the modulation of regulatory and effector T cells |
| WO2015116178A1 (en) | 2014-01-31 | 2015-08-06 | Thomas Jefferson University | Fusion proteins for modulating regulatory and effector t cells |
| US10533054B2 (en) * | 2013-01-31 | 2020-01-14 | Thomas Jefferson University | Agonist fusion protein for CD40 and OX40 and methods of stimulating the immune system |
| WO2014121093A1 (en) | 2013-01-31 | 2014-08-07 | Thomas Jefferson University | Fusion proteins that facilitate cancer cell destruction |
| WO2014121085A1 (en) | 2013-01-31 | 2014-08-07 | Thomas Jefferson University | Pd-l1 and pd-l2-based fusion proteins and uses thereof |
| KR102363191B1 (ko) | 2013-02-26 | 2022-02-17 | 메모리얼 슬로안 케터링 캔서 센터 | 면역치료용 조성물 및 방법 |
| EP2970512B1 (en) | 2013-03-12 | 2018-10-10 | Biocon Limited | Fusion immunomodulatory proteins and methods for making same |
| US10196435B2 (en) | 2013-11-18 | 2019-02-05 | University Of Southern California | OX40L fusion protein for the immunotherapy of tumors of veterinary animals |
| BR112016013963A2 (pt) | 2013-12-17 | 2017-10-10 | Genentech Inc | terapia de combinação compreendendo agonistas de ligação de ox40 e antagonistas de ligação do eixo de pd-1 |
| WO2015104406A2 (en) | 2014-01-13 | 2015-07-16 | Pieris Ag | Multi-specific polypeptide useful for localized tumor immunomodulation |
| CA2936244A1 (en) | 2014-01-21 | 2015-07-30 | Medimmune, Llc | Compositions and methods for modulating and redirecting immune responses |
| WO2015148416A1 (en) | 2014-03-24 | 2015-10-01 | Deqiang Jing | Novel recombinant bi-functional fusion proteins, preparation and use thereof |
| CN106456734A (zh) | 2014-05-29 | 2017-02-22 | 免疫医疗有限责任公司 | Ox40l融合蛋白及其用途 |
| EP3160497A4 (en) | 2014-06-27 | 2018-01-17 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Conjugates for immunotherapy |
| CN113621075B (zh) | 2014-08-08 | 2024-09-20 | Alx肿瘤生物技术公司 | SIRP-α变体构建体及其用途 |
| PL3482766T3 (pl) | 2014-08-11 | 2020-11-16 | Delinia, Inc. | Modyfikowane warianty il-2, które selektywnie aktywują limfocyty t regulatorowe do leczenia chorób autoimmunologicznych |
| LT3180363T (lt) | 2014-08-15 | 2019-11-25 | Merck Patent Gmbh | Sirp-alfa imunoglobulino sulieti baltymai |
| KR20170096112A (ko) | 2014-11-17 | 2017-08-23 | 제넨테크, 인크. | Ox40 결합 효능제 및 pd-1 축 결합 길항제를 포함하는 조합 요법 |
| US11161907B2 (en) | 2015-02-02 | 2021-11-02 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| MA41460A (fr) | 2015-02-03 | 2017-12-12 | Oncomed Pharm Inc | Agents de liaison à la tnfrsf et leurs utilisations |
| BR112017016681A2 (pt) * | 2015-02-06 | 2018-04-10 | Heat Biologics Inc | vetor de coexpressão de vacina e moléculas coestimulatórias |
| SMT202100132T1 (it) | 2015-04-13 | 2021-05-07 | Five Prime Therapeutics Inc | Terapia di combinazione per il cancro |
| WO2016166139A1 (en) | 2015-04-14 | 2016-10-20 | Eberhard Karls Universität Tübingen | Bispecific fusion proteins for enhancing immune responses of lymphocytes against tumor cells |
| DK3298043T3 (da) | 2015-05-18 | 2021-02-15 | Ab Initio Biotherapeutics Inc | SIRP-polypeptidsammensætninger og fremgangsmåder til anvendelse |
| IL294679B2 (en) | 2015-08-07 | 2023-10-01 | Alx Oncology Inc | Structures with a SIRP-alpha site or its variant |
| IL316210A (en) * | 2015-10-01 | 2024-12-01 | Heat Biologics Inc | Compounds and methods for connecting type 1 and 2 extracellular complexes as heterologous chimeric proteins |
| WO2018075960A1 (en) | 2016-10-21 | 2018-04-26 | Tioma Therapeutics, Inc. | Therapeutic cd47 antibodies |
| EP3585409A4 (en) | 2017-02-27 | 2020-12-02 | Shattuck Labs, Inc. | CHEMERICAL PROTEINS BASED ON CSF1R |
-
2018
- 2018-02-27 EP EP18756880.3A patent/EP3585409A4/en active Pending
- 2018-02-27 SG SG11201906464UA patent/SG11201906464UA/en unknown
- 2018-02-27 MX MX2019010173A patent/MX2019010173A/es unknown
- 2018-02-27 CN CN201880014002.2A patent/CN110381974A/zh active Pending
- 2018-02-27 US US16/484,853 patent/US11267856B2/en active Active
- 2018-02-27 WO PCT/US2018/020039 patent/WO2018157164A1/en not_active Ceased
- 2018-02-27 KR KR1020197027869A patent/KR20190124247A/ko not_active Ceased
- 2018-02-27 BR BR112019017713A patent/BR112019017713A2/pt not_active Application Discontinuation
- 2018-02-27 CA CA3054132A patent/CA3054132A1/en active Pending
- 2018-02-27 JP JP2019545954A patent/JP7121029B2/ja active Active
- 2018-02-27 AU AU2018223822A patent/AU2018223822A1/en not_active Abandoned
- 2018-12-18 US US16/223,332 patent/US10513548B2/en active Active
-
2019
- 2019-06-28 PH PH12019501534A patent/PH12019501534A1/en unknown
- 2019-07-21 IL IL268197A patent/IL268197A/en unknown
- 2019-08-25 SA SA519402522A patent/SA519402522B1/ar unknown
- 2019-09-20 ZA ZA2019/06235A patent/ZA201906235B/en unknown
- 2019-11-06 US US16/675,475 patent/US11267857B2/en active Active
-
2022
- 2022-01-28 US US17/587,447 patent/US20220144909A1/en not_active Abandoned
- 2022-08-04 JP JP2022125121A patent/JP2022159393A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7121029B2 (ja) | 2022-08-17 |
| CN110381974A (zh) | 2019-10-25 |
| EP3585409A4 (en) | 2020-12-02 |
| EP3585409A1 (en) | 2020-01-01 |
| US20220144909A1 (en) | 2022-05-12 |
| BR112019017713A2 (pt) | 2020-04-07 |
| KR20190124247A (ko) | 2019-11-04 |
| JP2020508063A (ja) | 2020-03-19 |
| JP2022159393A (ja) | 2022-10-17 |
| RU2019129835A (ru) | 2021-03-29 |
| US20200123214A1 (en) | 2020-04-23 |
| MX2019010173A (es) | 2019-11-21 |
| CA3054132A1 (en) | 2018-08-30 |
| US11267857B2 (en) | 2022-03-08 |
| SA519402522B1 (ar) | 2023-03-12 |
| SG11201906464UA (en) | 2019-08-27 |
| WO2018157164A1 (en) | 2018-08-30 |
| RU2019129835A3 (enExample) | 2021-07-16 |
| US20190382466A1 (en) | 2019-12-19 |
| US10513548B2 (en) | 2019-12-24 |
| US11267856B2 (en) | 2022-03-08 |
| PH12019501534A1 (en) | 2019-09-09 |
| AU2018223822A1 (en) | 2019-07-11 |
| US20190169249A1 (en) | 2019-06-06 |
| ZA201906235B (en) | 2021-04-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUS2400043I1 (hu) | VIII-as faktor kimérafehérjék és alkalmazásuk | |
| IL268198A (en) | based chimeric proteins - TIGIT and LIGHT | |
| ZA201704231B (en) | Chimeric protein | |
| IL246898B (en) | chimeric alkaline phosphatase proteins | |
| GB201509413D0 (en) | Fusion protein | |
| GB201502305D0 (en) | Protein | |
| GB201502306D0 (en) | Protein | |
| GB201719557D0 (en) | Polypeptide | |
| ZA201906235B (en) | Csf1r-based chimeric proteins | |
| GB201506223D0 (en) | Chimeric protein | |
| GB201504691D0 (en) | Fusion protein | |
| ZA202003845B (en) | Fusion proteins | |
| GB201608197D0 (en) | Novel proteins | |
| GB201505306D0 (en) | Chimeric polypeptides | |
| GB201515745D0 (en) | Proteins | |
| GB201511787D0 (en) | Proteins | |
| IL281088A (en) | FLT3L - based chimeric proteins | |
| IL268170A (en) | vsig8-based chimeric proteins | |
| GB2558968B (en) | G Proteins | |
| GB201513033D0 (en) | Proteins | |
| ZA201801394B (en) | Fusion protein | |
| EP3204427A4 (en) | Chimeric proteins | |
| GB201712792D0 (en) | Fusion protein | |
| GB201522610D0 (en) | Protein | |
| HK40019319A (en) | Csf1r-based chimeric proteins |