IL260846A - - Google Patents

Info

Publication number
IL260846A
IL260846A IL26084618A IL26084618A IL260846A IL 260846 A IL260846 A IL 260846A IL 26084618 A IL26084618 A IL 26084618A IL 26084618 A IL26084618 A IL 26084618A IL 260846 A IL260846 A IL 260846A
Authority
IL
Israel
Application number
IL26084618A
Other languages
English (en)
Other versions
IL260846B (en
IL260846B2 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of IL260846A publication Critical patent/IL260846A/en
Publication of IL260846B publication Critical patent/IL260846B/en
Publication of IL260846B2 publication Critical patent/IL260846B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL260846A 2016-01-29 2018-07-29 Antigen binding proteins that bind pd-l1 IL260846B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662288912P 2016-01-29 2016-01-29
PCT/US2017/015429 WO2017132562A1 (en) 2016-01-29 2017-01-27 Antigen binding proteins that bind pd-l1

Publications (3)

Publication Number Publication Date
IL260846A true IL260846A (enExample) 2018-09-20
IL260846B IL260846B (en) 2022-10-01
IL260846B2 IL260846B2 (en) 2023-02-01

Family

ID=59386438

Family Applications (1)

Application Number Title Priority Date Filing Date
IL260846A IL260846B2 (en) 2016-01-29 2018-07-29 Antigen binding proteins that bind pd-l1

Country Status (18)

Country Link
US (4) US10118963B2 (enExample)
EP (1) EP3408400B1 (enExample)
JP (3) JP6883590B2 (enExample)
KR (1) KR20190026642A (enExample)
CN (2) CN116333124A (enExample)
AU (1) AU2017212717B2 (enExample)
BR (1) BR112018015480A2 (enExample)
CA (1) CA3013051A1 (enExample)
CL (1) CL2018002034A1 (enExample)
EA (1) EA037855B1 (enExample)
ES (1) ES2986360T3 (enExample)
IL (1) IL260846B2 (enExample)
MX (2) MX2018009228A (enExample)
NZ (1) NZ745357A (enExample)
PH (1) PH12018501611A1 (enExample)
SG (1) SG11201806496SA (enExample)
TW (1) TWI760323B (enExample)
WO (1) WO2017132562A1 (enExample)

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KR102410078B1 (ko) 2012-05-31 2022-06-22 소렌토 쎄라퓨틱스, 인코포레이티드 Pd-l1에 결합하는 항원 결합 단백질
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
AU2017212717B2 (en) 2016-01-29 2023-11-16 Yuhan Corporation Antigen binding proteins that bind PD-L1
CA3026474A1 (en) 2016-06-20 2017-12-28 Kymab Limited Anti-pd-l1 and il-2 cytokines
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
US11779604B2 (en) 2016-11-03 2023-10-10 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses and methods
US12152074B2 (en) 2018-03-22 2024-11-26 CeingeBiotecnologie Avanzate Franco Salvatore Scarl Antagonistic PD-1, PD-L1 and LAG-3 binding proteins
AU2018418224B2 (en) * 2018-04-09 2025-04-17 Oricell Therapeutics Co., Ltd. Anti-PD-L1 antibody and use thereof
WO2019227490A1 (en) * 2018-06-01 2019-12-05 Tayu Huaxia Biotech Medical Group Co., Ltd. Compositions and methods for imaging
CN117442717A (zh) * 2018-06-01 2024-01-26 大有华夏生物医药集团有限公司 治疗疾病或病况的组合物及其用途
EP3841126A4 (en) * 2018-08-20 2022-08-10 1Globe Biomedical Co., Ltd. NOVEL CANCER IMMUNOTHERAPY ANTIBODY COMPOSITIONS
WO2020123543A2 (en) * 2018-12-11 2020-06-18 Sanford Burnham Prebys Medical Discovery Institute Models and methods useful for the treatment of serrated colorectal cancer
JP7538130B2 (ja) 2019-01-23 2024-08-21 タユー ファシャ バイオテック メディカル グループ カンパニー, リミテッド 抗pd-l1ダイアボディおよびその使用
CA3136453A1 (en) 2019-04-18 2020-10-22 Qlsf Biotherapeutics Inc. Humanized anti-pd-l1 antibodies
JP2022521958A (ja) 2019-08-29 2022-04-13 榮昌生物制薬(烟台)股▲フン▼有限公司 抗pd-l1抗体及びその応用
JP2023532279A (ja) * 2020-06-26 2023-07-27 ソレント・セラピューティクス・インコーポレイテッド 免疫調節性融合タンパク質を発現する腫瘍溶解性単純ヘルペスウイルス(hsv)
EP4208204A1 (en) 2020-09-02 2023-07-12 Mayo Foundation for Medical Education and Research Antibody-nanoparticle complexes and methods for making and using the same
WO2022103242A1 (ko) 2020-11-16 2022-05-19 주식회사 이뮨온시아 면역항암제에 대한 치료 반응성을 예측하기 위한 바이오마커 및 이의 용도
CN117279948A (zh) 2021-05-07 2023-12-22 益免安协公司 与cd47和pd-l1特异性结合的双特异性抗体
CA3221925A1 (en) 2021-06-09 2022-12-15 Sorrento Therapeutics, Inc. Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device
WO2024064640A2 (en) * 2022-09-19 2024-03-28 Sonoma Biotherapeutics, Inc. Citrullinated antigen-specific chimeric antigen receptors for targeting regulatory t cells to treat hidradenitis suppurativa
CN120813375A (zh) 2023-01-30 2025-10-17 凯玛布有限公司 抗体
WO2025183487A1 (en) * 2024-02-29 2025-09-04 Yuhan Corporation Anti-tigit/anti-pd-l1 bispecific antibody and use thereof
AU2024416010A1 (en) 2024-04-13 2025-10-30 Immuneoncia Therapeutics, Inc. Neoadjuvant immunotherapy using PD-L1 inhibitor for treating cancer

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Also Published As

Publication number Publication date
TWI760323B (zh) 2022-04-11
US10919964B2 (en) 2021-02-16
US20190092861A1 (en) 2019-03-28
EA201891709A1 (ru) 2019-01-31
BR112018015480A2 (pt) 2019-05-21
CN109715821B (zh) 2022-09-06
JP2019507183A (ja) 2019-03-14
US10118963B2 (en) 2018-11-06
SG11201806496SA (en) 2018-08-30
EP3408400A1 (en) 2018-12-05
EP3408400C0 (en) 2024-06-26
PH12018501611A1 (en) 2019-04-08
TW201736400A (zh) 2017-10-16
US20210147539A1 (en) 2021-05-20
JP6883590B2 (ja) 2021-06-09
CA3013051A1 (en) 2017-08-03
WO2017132562A1 (en) 2017-08-03
IL260846B (en) 2022-10-01
CN116333124A (zh) 2023-06-27
ES2986360T3 (es) 2024-11-11
EA037855B1 (ru) 2021-05-27
KR20190026642A (ko) 2019-03-13
JP7140867B2 (ja) 2022-09-21
AU2017212717A1 (en) 2018-09-06
MX2022011659A (es) 2022-10-13
EP3408400B1 (en) 2024-06-26
WO2017132562A8 (en) 2017-09-08
US20170218066A1 (en) 2017-08-03
IL260846B2 (en) 2023-02-01
EP3408400A4 (en) 2019-11-27
US20240190959A1 (en) 2024-06-13
JP2021102633A (ja) 2021-07-15
NZ745357A (en) 2025-08-29
CL2018002034A1 (es) 2019-03-15
AU2017212717B2 (en) 2023-11-16
MX2018009228A (es) 2019-07-08
JP2022095910A (ja) 2022-06-28
CN109715821A (zh) 2019-05-03
US11919952B2 (en) 2024-03-05

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