IL250251A0 - Compounds containing tricyclic nitrogen for the treatment of Neisseria gonorrhoeae infection - Google Patents
Compounds containing tricyclic nitrogen for the treatment of Neisseria gonorrhoeae infectionInfo
- Publication number
- IL250251A0 IL250251A0 IL250251A IL25025117A IL250251A0 IL 250251 A0 IL250251 A0 IL 250251A0 IL 250251 A IL250251 A IL 250251A IL 25025117 A IL25025117 A IL 25025117A IL 250251 A0 IL250251 A0 IL 250251A0
- Authority
- IL
- Israel
- Prior art keywords
- containing compounds
- nitrogen containing
- neisseria gonorrhoea
- tricyclic nitrogen
- treating neisseria
- Prior art date
Links
- 206010018612 Gonorrhoea Diseases 0.000 title 1
- 241000588653 Neisseria Species 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462040488P | 2014-08-22 | 2014-08-22 | |
| PCT/IB2015/056325 WO2016027249A1 (en) | 2014-08-22 | 2015-08-20 | Tricyclic nitrogen containing compounds for treating neisseria gonorrhoea infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL250251A0 true IL250251A0 (en) | 2017-03-30 |
Family
ID=54072911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL250251A IL250251A0 (en) | 2014-08-22 | 2017-01-23 | Compounds containing tricyclic nitrogen for the treatment of Neisseria gonorrhoeae infection |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10702521B2 (enExample) |
| EP (2) | EP3182973B1 (enExample) |
| JP (2) | JP6546654B2 (enExample) |
| KR (1) | KR20170043603A (enExample) |
| CN (2) | CN106659717B (enExample) |
| AR (1) | AR101674A1 (enExample) |
| AU (1) | AU2015304847B2 (enExample) |
| BR (1) | BR112017003705B1 (enExample) |
| CA (1) | CA2958800C (enExample) |
| CL (1) | CL2017000391A1 (enExample) |
| CO (1) | CO2017001658A2 (enExample) |
| CR (1) | CR20170069A (enExample) |
| DO (1) | DOP2017000049A (enExample) |
| EA (1) | EA031589B1 (enExample) |
| ES (1) | ES2759303T3 (enExample) |
| IL (1) | IL250251A0 (enExample) |
| MX (1) | MX2017002321A (enExample) |
| PE (1) | PE20170501A1 (enExample) |
| PH (1) | PH12017500315A1 (enExample) |
| SG (1) | SG11201700566SA (enExample) |
| TW (1) | TW201618779A (enExample) |
| WO (1) | WO2016027249A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR101674A1 (es) * | 2014-08-22 | 2017-01-04 | Glaxosmithkline Ip Dev Ltd | Uso de un compuesto tricíclico que contiene nitrógeno |
| EP3468975B1 (en) | 2016-06-08 | 2020-04-01 | Aziende Chimiche Riunite Angelini Francesco A.C.R. | New antibacterial compounds |
| US20200077658A1 (en) | 2016-12-16 | 2020-03-12 | Basf Se | Pesticidal Compounds |
| US20220184071A1 (en) * | 2019-04-03 | 2022-06-16 | Glaxosmithkline Intellectual Property Development Limited | Gepotidacin for use in the treatment of bacterial urinary tract infections |
| BR112021018815A2 (pt) * | 2019-04-03 | 2022-03-03 | Glaxosmithkline Ip Dev Ltd | Gepotidacina para uso no tratamento de infecções bacterianas do trato urinário |
| GB201909191D0 (en) * | 2019-06-26 | 2019-08-07 | Ucb Biopharma Sprl | Therapeutic agents |
| CN114173789A (zh) * | 2019-07-05 | 2022-03-11 | 葛兰素史克知识产权发展有限公司 | 用于治疗由生殖支原体引起的感染的组合 |
| US12195458B2 (en) | 2019-12-02 | 2025-01-14 | Storm Therapeutics Limited | Polyheterocyclic compounds as METTL3 inhibitors |
| JP2023528560A (ja) * | 2020-04-02 | 2023-07-05 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | ゲポチダシンを用いて淋菌感染症を治療するためのレジメン |
| EP4142731A1 (en) * | 2020-04-28 | 2023-03-08 | Noorik Biopharmaceuticals AG | Treatment of pulmonary complications of coronavirus infections |
| CN115667261A (zh) * | 2020-04-29 | 2023-01-31 | 葛兰素史克知识产权发展有限公司 | 吉泊达星的结晶形式 |
| WO2022167515A1 (en) | 2021-02-05 | 2022-08-11 | Glaxosmithkline Intellectual Property Development Limited | Oral solid dose formulations |
| EP4316463A1 (en) | 2022-08-02 | 2024-02-07 | GlaxoSmithKline Intellectual Property Development Limited | Novel formulation |
| CN119546302A (zh) | 2022-09-26 | 2025-02-28 | 葛兰素史密斯克莱知识产权发展有限公司 | 用于治疗细菌性前列腺炎的吉泊达星 |
| CN121537412B (zh) * | 2026-01-16 | 2026-04-03 | 南京道尔医药研究院有限公司 | 一种吉泊达星甲磺酸盐的制备方法 |
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| HRP20100194T8 (hr) | 2005-10-21 | 2010-06-30 | Glaxo Group Limited | Perikondenzirani triciklički spojevi, korisni kao antibakterijska sredstva |
| US7855201B2 (en) | 2005-12-06 | 2010-12-21 | Merck Sharp & Dohme. Corp. | Morpholine carboxamide prokineticin receptor antagonists |
| WO2007071936A1 (en) | 2005-12-22 | 2007-06-28 | Glaxo Group Limited | Heterocyclic compounds, their preparation and their use as antibacterials |
| ATE481406T1 (de) | 2006-04-06 | 2010-10-15 | Glaxo Group Ltd | Pyrrolochinoxalinonderivate als antibakterielle mittel |
| US7709496B2 (en) | 2006-04-06 | 2010-05-04 | Glaxo Group Limited | Antibacterial agents |
| GB0608263D0 (en) | 2006-04-26 | 2006-06-07 | Glaxo Group Ltd | Compounds |
| EP2029612A1 (en) | 2006-06-09 | 2009-03-04 | Glaxo Group Limited | Substituted 1-methyl-1h-quinolin-2-ones and 1-methyl-1h-1,5-naphthyridin-2-ones as antibacterials |
| GB0613208D0 (en) | 2006-07-03 | 2006-08-09 | Glaxo Group Ltd | Compounds |
| EP1992628A1 (en) | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| PT2137196E (pt) * | 2007-04-20 | 2010-12-16 | Glaxo Group Ltd | Compostos tricíclicos contendo azoto como agentes antibacterianos |
| CN102105473B (zh) | 2008-05-23 | 2013-05-08 | 葛兰素集团有限公司 | 三环含氮化合物及其作为抗菌剂的用途 |
| JP2012505866A (ja) * | 2008-10-17 | 2012-03-08 | グラクソ グループ リミテッド | 抗菌剤として使用される三環式窒素化合物 |
| AR101674A1 (es) * | 2014-08-22 | 2017-01-04 | Glaxosmithkline Ip Dev Ltd | Uso de un compuesto tricíclico que contiene nitrógeno |
-
2015
- 2015-08-20 AR ARP150102680A patent/AR101674A1/es unknown
- 2015-08-20 KR KR1020177007353A patent/KR20170043603A/ko not_active Withdrawn
- 2015-08-20 JP JP2017510528A patent/JP6546654B2/ja active Active
- 2015-08-20 PE PE2017000215A patent/PE20170501A1/es not_active Application Discontinuation
- 2015-08-20 SG SG11201700566SA patent/SG11201700566SA/en unknown
- 2015-08-20 CN CN201580045166.8A patent/CN106659717B/zh active Active
- 2015-08-20 CA CA2958800A patent/CA2958800C/en active Active
- 2015-08-20 BR BR112017003705-0A patent/BR112017003705B1/pt active IP Right Grant
- 2015-08-20 EP EP15762763.9A patent/EP3182973B1/en active Active
- 2015-08-20 AU AU2015304847A patent/AU2015304847B2/en not_active Ceased
- 2015-08-20 MX MX2017002321A patent/MX2017002321A/es unknown
- 2015-08-20 EP EP19197439.3A patent/EP3639824A1/en not_active Withdrawn
- 2015-08-20 CN CN201910738641.XA patent/CN110403939A/zh active Pending
- 2015-08-20 TW TW104127098A patent/TW201618779A/zh unknown
- 2015-08-20 EA EA201790442A patent/EA031589B1/ru not_active IP Right Cessation
- 2015-08-20 WO PCT/IB2015/056325 patent/WO2016027249A1/en not_active Ceased
- 2015-08-20 US US15/505,715 patent/US10702521B2/en active Active
- 2015-08-20 ES ES15762763T patent/ES2759303T3/es active Active
- 2015-08-20 CR CR20170069A patent/CR20170069A/es unknown
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2017
- 2017-01-23 IL IL250251A patent/IL250251A0/en unknown
- 2017-02-16 CL CL2017000391A patent/CL2017000391A1/es unknown
- 2017-02-21 DO DO2017000049A patent/DOP2017000049A/es unknown
- 2017-02-21 PH PH12017500315A patent/PH12017500315A1/en unknown
- 2017-02-21 CO CONC2017/0001658A patent/CO2017001658A2/es unknown
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2019
- 2019-06-21 JP JP2019115462A patent/JP2019189629A/ja not_active Withdrawn
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2020
- 2020-07-01 US US16/918,084 patent/US11229646B2/en active Active
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