IL231677A - 5-Hydroxy-H1 Crystal-Imidazole-4-Carboxamide 4./3 Hydrate and Method of Manufacturing - Google Patents
5-Hydroxy-H1 Crystal-Imidazole-4-Carboxamide 4./3 Hydrate and Method of ManufacturingInfo
- Publication number
- IL231677A IL231677A IL231677A IL23167714A IL231677A IL 231677 A IL231677 A IL 231677A IL 231677 A IL231677 A IL 231677A IL 23167714 A IL23167714 A IL 23167714A IL 231677 A IL231677 A IL 231677A
- Authority
- IL
- Israel
- Prior art keywords
- carboxamide
- imidazole
- hydrate
- hydroxy
- crystal
- Prior art date
Links
- UEWSIIBPZOBMBL-UHFFFAOYSA-N 5-hydroxyimidazole-4-carboxamide Chemical compound NC(=O)C1=C([O-])[NH2+]C=N1 UEWSIIBPZOBMBL-UHFFFAOYSA-N 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011213500 | 2011-09-28 | ||
| JP2011213501 | 2011-09-28 | ||
| PCT/JP2012/075106 WO2013047758A1 (ja) | 2011-09-28 | 2012-09-28 | ５－ヒドロキシ－１ｈ－イミダゾール－４－カルボキサミド水和物の結晶及び５－ヒドロキシ－１ｈ－イミダゾール－４－カルボキサミド・３／４水和物の結晶及びその製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL231677A0 IL231677A0 (en) | 2014-05-28 |
| IL231677A true IL231677A (en) | 2017-01-31 |
Family
ID=47995783
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL231677A IL231677A (en) | 2011-09-28 | 2014-03-24 | 5-Hydroxy-H1 Crystal-Imidazole-4-Carboxamide 4./3 Hydrate and Method of Manufacturing |
| IL246754A IL246754A (en) | 2011-09-28 | 2016-07-13 | Method for Making 5-Hydroxy Crystal-H1-Imidazole-4-Carboxamide 4/3 Hydrate |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL246754A IL246754A (en) | 2011-09-28 | 2016-07-13 | Method for Making 5-Hydroxy Crystal-H1-Imidazole-4-Carboxamide 4/3 Hydrate |
Country Status (13)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2014CN02346A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2011-09-28 | 2015-06-19 | Fujifilm Corp | |
| BR112015015282A2 (pt) | 2013-01-15 | 2017-07-11 | Fujifilm Corp | sulfato de 5 - hidróxi - 1h - imidazol - 4 - carboxamida |
| AU2015205151B2 (en) * | 2014-01-10 | 2018-02-01 | Fujifilm Corporation | 5-hydroxy-1H-imidazole-4-carboxamide effective-dose/sensitivity prediction method and prediction device, xanthosine-monophosphate-amount measurement method, and myelodysplastic-syndrome treatment agent and treatment method |
| WO2018051971A1 (ja) * | 2016-09-13 | 2018-03-22 | 富士フイルム株式会社 | Ｍｌｌ関連白血病の予防または治療のための医薬、方法、使用及び化合物 |
| WO2019082898A1 (ja) | 2017-10-27 | 2019-05-02 | 富士フイルム株式会社 | ５－ヒドロキシ－１ｈ－イミダゾール－４－カルボキサミド・３／４水和物の製造方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4181731A (en) * | 1976-09-07 | 1980-01-01 | Sumitomo Chemical Company, Limited | Novel therapeutic application of 4-carbamoyl-5-hydroxyimidazole |
| JPS5625165A (en) * | 1979-08-08 | 1981-03-10 | Sumitomo Chem Co Ltd | Novel imidazole derivative |
| JPS5824569A (ja) | 1981-08-05 | 1983-02-14 | Sumitomo Chem Co Ltd | イミダゾ−ル誘導体の精製方法 |
| US4503235A (en) * | 1983-03-11 | 1985-03-05 | Warner-Lambert Company | Process for producing 4-carbamoyl-1H-imidazolium-5-olate |
| JPS60185727A (ja) | 1984-03-05 | 1985-09-21 | Sumitomo Chem Co Ltd | ４−カルバモイルイミダゾリウム−５−オレ−ト製剤の安定化法 |
| CA2152863A1 (en) | 1994-07-26 | 1996-01-27 | Yeun-Kwei Han | Preparation of acyclovir |
| US5567816A (en) | 1994-07-26 | 1996-10-22 | Syntex (U.S.A.) Inc. | Preparation of acyclovir using 1,3 dioxolane |
| PT1320527E (pt) | 2000-09-29 | 2008-10-24 | Basf Se | Processo para a preparação de 5-cloro-4-metilpirazóis 1-substituídos |
| JP2002265601A (ja) | 2001-03-07 | 2002-09-18 | Rikogaku Shinkokai | イミド樹脂 |
| JP2008530179A (ja) * | 2005-02-16 | 2008-08-07 | ソルベイ・フアーマシユーチカルズ・ベー・ブイ | カンナビノイドｃｂ２受容体モジュレーターとしての１ｈ−イミダゾール誘導体 |
| UA94737C2 (ru) * | 2006-02-24 | 2011-06-10 | Лексикон Фармасьютикалз, Инк. | Соединения на основе имидазола, композиция, которая их содержит, и их применение |
| JP5266010B2 (ja) | 2007-09-14 | 2013-08-21 | 富士フイルム株式会社 | ４−カルバモイル−５−ヒドロキシ−イミダゾール誘導体のスルホン酸塩化合物 |
| KR100982720B1 (ko) * | 2008-02-04 | 2010-09-17 | 주식회사 파마코스텍 | 4-카르바모일-1-β-Ｄ-리보푸라노실이미다졸륨-5-올레이트의 생산을 위한 중간체로서의 2-아미노말론아미드의제조방법 |
| IN2014CN02346A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2011-09-28 | 2015-06-19 | Fujifilm Corp | |
| TWI573791B (zh) | 2011-09-28 | 2017-03-11 | 富士軟片股份有限公司 | ５－羥基－１ｈ－咪唑－４－甲醯胺．３／４水合物及其結晶之製造方法 |
-
2012
- 2012-09-28 IN IN2346CHN2014 patent/IN2014CN02346A/en unknown
- 2012-09-28 AU AU2012317424A patent/AU2012317424B2/en not_active Ceased
- 2012-09-28 BR BR112014007436A patent/BR112014007436A2/pt not_active Application Discontinuation
- 2012-09-28 WO PCT/JP2012/075106 patent/WO2013047758A1/ja active Application Filing
- 2012-09-28 CA CA2850196A patent/CA2850196A1/en active Pending
- 2012-09-28 RU RU2014111810A patent/RU2630682C2/ru not_active IP Right Cessation
- 2012-09-28 KR KR1020147008200A patent/KR101970509B1/ko not_active Expired - Fee Related
- 2012-09-28 SG SG11201400974VA patent/SG11201400974VA/en unknown
- 2012-09-28 MX MX2014003638A patent/MX354498B/es active IP Right Grant
- 2012-09-28 RU RU2017125796A patent/RU2672560C1/ru not_active IP Right Cessation
- 2012-09-28 EP EP12835728.2A patent/EP2762469B1/en not_active Not-in-force
- 2012-09-28 CN CN201280047308.0A patent/CN103827093B/zh not_active Expired - Fee Related
-
2014
- 2014-03-24 IL IL231677A patent/IL231677A/en active IP Right Grant
- 2014-03-26 US US14/226,364 patent/US9108928B2/en active Active
-
2015
- 2015-07-10 US US14/796,602 patent/US9567303B2/en not_active Expired - Fee Related
-
2016
- 2016-07-13 IL IL246754A patent/IL246754A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014111810A (ru) | 2015-11-10 |
| EP2762469A4 (en) | 2015-01-14 |
| KR20140069052A (ko) | 2014-06-09 |
| CN103827093B (zh) | 2016-06-15 |
| NZ622928A (en) | 2015-04-24 |
| AU2012317424A1 (en) | 2014-04-17 |
| IL231677A0 (en) | 2014-05-28 |
| CN103827093A (zh) | 2014-05-28 |
| HK1197406A1 (zh) | 2015-01-16 |
| RU2630682C2 (ru) | 2017-09-12 |
| US9108928B2 (en) | 2015-08-18 |
| MX2014003638A (es) | 2014-05-21 |
| MX354498B (es) | 2018-03-08 |
| AU2012317424B2 (en) | 2017-05-18 |
| EP2762469B1 (en) | 2016-11-23 |
| IL246754A (en) | 2017-08-31 |
| AU2012317424A8 (en) | 2014-07-03 |
| CA2850196A1 (en) | 2013-04-04 |
| US20150315156A1 (en) | 2015-11-05 |
| EP2762469A1 (en) | 2014-08-06 |
| IN2014CN02346A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-06-19 |
| BR112014007436A2 (pt) | 2017-04-04 |
| SG11201400974VA (en) | 2014-09-26 |
| US20140275568A1 (en) | 2014-09-18 |
| WO2013047758A1 (ja) | 2013-04-04 |
| US9567303B2 (en) | 2017-02-14 |
| RU2672560C1 (ru) | 2018-11-16 |
| KR101970509B1 (ko) | 2019-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |