IL231167A0 - Neutralizing antibodies to primary exotoxins tacda and tcd of Clostridium difficile - Google Patents
Neutralizing antibodies to primary exotoxins tacda and tcd of Clostridium difficileInfo
- Publication number
- IL231167A0 IL231167A0 IL231167A IL23116714A IL231167A0 IL 231167 A0 IL231167 A0 IL 231167A0 IL 231167 A IL231167 A IL 231167A IL 23116714 A IL23116714 A IL 23116714A IL 231167 A0 IL231167 A0 IL 231167A0
- Authority
- IL
- Israel
- Prior art keywords
- tcdb
- clostridium difficile
- neutralising antibodies
- tcda
- major
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1282—Clostridium (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/91091—Glycosyltransferases (2.4)
- G01N2333/91097—Hexosyltransferases (general) (2.4.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161535532P | 2011-09-16 | 2011-09-16 | |
| US201261638731P | 2012-04-26 | 2012-04-26 | |
| PCT/GB2012/052222 WO2013038156A1 (en) | 2011-09-16 | 2012-09-10 | Neutralising antibodies to the major exotoxins tcda and tcdb of clostridium difficile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL231167A0 true IL231167A0 (en) | 2014-04-30 |
Family
ID=46881094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL231167A IL231167A0 (en) | 2011-09-16 | 2014-02-26 | Neutralizing antibodies to primary exotoxins tacda and tcd of Clostridium difficile |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US10752676B2 (https=) |
| EP (2) | EP2758432B1 (https=) |
| JP (3) | JP6152107B2 (https=) |
| KR (1) | KR20140063825A (https=) |
| CN (2) | CN103958544B (https=) |
| AU (1) | AU2012307157B2 (https=) |
| BR (1) | BR112014006175B1 (https=) |
| CA (1) | CA2848611A1 (https=) |
| CL (1) | CL2014000491A1 (https=) |
| CO (1) | CO6930310A2 (https=) |
| CY (1) | CY1121673T1 (https=) |
| DK (1) | DK2758432T3 (https=) |
| EA (1) | EA032475B1 (https=) |
| EC (1) | ECSP14013316A (https=) |
| ES (1) | ES2729278T3 (https=) |
| HK (1) | HK1199463A1 (https=) |
| HR (1) | HRP20190917T1 (https=) |
| HU (1) | HUE043661T2 (https=) |
| IL (1) | IL231167A0 (https=) |
| LT (1) | LT2758432T (https=) |
| MX (1) | MX2014002769A (https=) |
| PE (1) | PE20141547A1 (https=) |
| PH (1) | PH12014500456A1 (https=) |
| PL (1) | PL2758432T3 (https=) |
| PT (1) | PT2758432T (https=) |
| SG (2) | SG11201400193SA (https=) |
| SI (1) | SI2758432T1 (https=) |
| TN (1) | TN2014000101A1 (https=) |
| WO (1) | WO2013038156A1 (https=) |
| ZA (1) | ZA201402760B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2758432T3 (pl) * | 2011-09-16 | 2019-08-30 | Ucb Biopharma Sprl | Przeciwciała neutralizujące przeciw głównym egzotoksynom tcda i tcdb z clostridium difficile |
| CN109776676A (zh) * | 2012-11-28 | 2019-05-21 | Cnj控股公司 | 针对艰难梭菌的抗体 |
| CN105451762A (zh) * | 2013-04-22 | 2016-03-30 | 俄克拉荷马州大学评议会 | 艰难梭菌疫苗及使用方法 |
| WO2015123767A1 (en) * | 2014-02-18 | 2015-08-27 | The Hospital For Sick Children | Compositions and methods for treating or preventing clostridium infection |
| US9717711B2 (en) | 2014-06-16 | 2017-08-01 | The Lauridsen Group | Methods and compositions for treating Clostridium difficile associated disease |
| WO2016178773A1 (en) * | 2015-04-06 | 2016-11-10 | Saureus, Inc. | System and method for detecting clostridium difficile toxins |
| US20180085458A1 (en) * | 2015-04-15 | 2018-03-29 | Medimmune, Llc | Methods for treating clostridium difficile infection and associated disease |
| HUE057952T2 (hu) | 2015-06-24 | 2022-06-28 | Hoffmann La Roche | Anti-transzferrin receptor antitestek testreszabott affinitással |
| EP3344276B1 (en) | 2015-09-03 | 2020-04-22 | The Board of Regents of the University of Oklahoma | Peptide inhibitors of clostridium difficile tcdb toxin |
| TWI873952B (zh) | 2015-10-02 | 2025-02-21 | 瑞士商赫孚孟拉羅股份公司 | 雙特異性抗‐人類cd20/人類轉鐵蛋白受體抗體及使用方法 |
| AR106189A1 (es) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO |
| USD864160S1 (en) | 2016-12-06 | 2019-10-22 | Samsung Electronics Co., Ltd. | Audio device |
| US12071666B2 (en) * | 2016-12-14 | 2024-08-27 | Merck Sharp & Dohme Llc | Human genetic markers associated with response to treatments that target clostridium difficile toxin B |
| CN110607314B (zh) * | 2019-10-31 | 2022-09-23 | 四川农业大学 | 一种TcdB RBD基因、重组RBD蛋白和应用 |
| CN111763263A (zh) * | 2020-07-09 | 2020-10-13 | 宁夏医科大学 | 一种艰难梭菌抗原及多克隆抗体的制备方法和检测试剂盒 |
| CN112500484B (zh) * | 2021-01-29 | 2021-06-08 | 迈杰转化医学研究(苏州)有限公司 | 一种抗trop2抗体及其应用 |
| CN121379975B (zh) * | 2025-12-25 | 2026-04-17 | 天津一瑞生物科技股份有限公司 | 抗TcdB毒素杂交瘤细胞株、单克隆抗体及应用 |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| DK336987D0 (da) | 1987-07-01 | 1987-07-01 | Novo Industri As | Immobiliseringsmetode |
| CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8907617D0 (en) | 1989-04-05 | 1989-05-17 | Celltech Ltd | Drug delivery system |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| EP0468520A3 (en) | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
| CA2090126C (en) | 1990-08-02 | 2002-10-22 | John W. Schrader | Methods for the production of proteins with a desired function |
| GB9112536D0 (en) | 1991-06-11 | 1991-07-31 | Celltech Ltd | Chemical compounds |
| GB9113120D0 (en) | 1991-06-18 | 1991-08-07 | Kodak Ltd | Photographic processing apparatus |
| GB9120467D0 (en) | 1991-09-26 | 1991-11-06 | Celltech Ltd | Anti-hmfg antibodies and process for their production |
| JP3723231B2 (ja) | 1991-12-23 | 2005-12-07 | ディミナコ アクチェンゲゼルシャフト | アジュバント |
| CA2138997C (en) | 1992-06-25 | 2003-06-03 | Jean-Paul Prieels | Vaccine composition containing adjuvants |
| US5776468A (en) | 1993-03-23 | 1998-07-07 | Smithkline Beecham Biologicals (S.A.) | Vaccine compositions containing 3-0 deacylated monophosphoryl lipid A |
| PL181241B1 (pl) | 1993-11-17 | 2001-06-29 | Deutsche Om Arzneimittel Gmbh | Disacharydy beta(1 6)glukozoaminowe, sposób wytwarzania disacharydu beta(1 6) glukozoaminowego, zawierająca je kompozycja farmaceutyczna i środek immunomodulujący i/lub przeciwnowotworowy oraz szczepionka |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| FR2716640B1 (fr) | 1994-02-28 | 1996-05-03 | Procedes Machines Speciales | Dispositif de centrage et de blocage d'une pièce en vue de son rodage à l'aide d'un rodoir à expansion. |
| EP1167379A3 (en) | 1994-07-15 | 2004-09-08 | University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| GB9620795D0 (en) | 1996-10-05 | 1996-11-20 | Smithkline Beecham Plc | Vaccines |
| ATE292980T1 (de) | 1996-10-11 | 2005-04-15 | Univ California | Immunostimulierende oligonucleotidekonjugate |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
| GB9711990D0 (en) | 1997-06-11 | 1997-08-06 | Smithkline Beecham Biolog | Vaccine |
| CA2302522C (en) | 1997-08-29 | 2010-08-17 | Antigenics Llc | Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as excipient |
| GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| AU1145699A (en) | 1997-09-05 | 1999-03-22 | Smithkline Beecham Biologicals (Sa) | Oil in water emulsions containing saponins |
| GB9812545D0 (en) | 1998-06-10 | 1998-08-05 | Celltech Therapeutics Ltd | Biological products |
| US6908963B2 (en) | 2001-10-09 | 2005-06-21 | Nektar Therapeutics Al, Corporation | Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith |
| WO2004041857A2 (en) * | 2002-06-17 | 2004-05-21 | Ballard Jimmy D | Mutant of clostridium difficile toxin b and methods of use |
| AU2002352938B8 (en) * | 2002-11-26 | 2009-10-08 | The University Of Chicago | Materials and methods for preventing and treating microbe-mediated epithelial disorders |
| ES2374068T3 (es) | 2002-12-03 | 2012-02-13 | Ucb Pharma, S.A. | Ensayo para identificar células productoras de anticuerpos. |
| GB0312481D0 (en) | 2003-05-30 | 2003-07-09 | Celltech R&D Ltd | Antibodies |
| GB0315457D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| GB0315450D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| ES2551439T5 (es) | 2003-07-01 | 2018-11-08 | Ucb Biopharma Sprl | Fragmentos Fab de anticuerpos modificados |
| DK2270045T3 (en) * | 2004-02-06 | 2015-04-07 | Univ Massachusetts | ANTIBODIES AGAINST CLOSTRIDIUM DIFFICILE TOXINES AND APPLICATIONS THEREOF |
| GB0411186D0 (en) | 2004-05-19 | 2004-06-23 | Celltech R&D Ltd | Biological products |
| GB0412181D0 (en) | 2004-06-01 | 2004-06-30 | Celltech R&D Ltd | Biological products |
| EP1830635B1 (en) | 2004-12-27 | 2015-10-28 | Huntsman Corporation Australia Pty Limited | Reduced foam dispersions and formulations therefor |
| WO2006071877A2 (en) | 2004-12-27 | 2006-07-06 | Progenics Pharmaceuticals (Nevada), Inc. | Orally deliverable and anti-toxin antibodies and methods for making and using them |
| WO2007146139A2 (en) * | 2006-06-08 | 2007-12-21 | Cornell Research Foundation, Inc. | Codon-optimized dna molecules encoding the receptor binding domains of clostridium difficile toxins a and b |
| GB0619291D0 (en) | 2006-09-29 | 2006-11-08 | Ucb Sa | Altered antibodies |
| EP2535349A1 (en) | 2007-09-26 | 2012-12-19 | UCB Pharma S.A. | Dual specificity antibody fusions |
| BRPI0906060A2 (pt) * | 2008-02-28 | 2015-12-01 | 3M Innovative Properties Co | anticorpos isolados, métodos de preparo de um anticorpo anti-clostridium difficile, composição e método para a detecção da presença de um esporo de clostridium difficile em uma amostra |
| BRPI0914251B1 (pt) * | 2008-06-25 | 2022-07-19 | Novartis Ag | Imunoligante recombinante, seu fragmento de ligação ao antígeno, uso dos mesmos, e composição |
| CA2737241C (en) | 2008-09-26 | 2017-08-29 | Ucb Pharma S.A. | Multivalent antibody fusion proteins |
| AU2010215275B2 (en) * | 2009-02-20 | 2016-03-31 | Micropharm Limited | Antibodies to Clostridium difficile toxins |
| US8986697B2 (en) * | 2010-04-15 | 2015-03-24 | Progenics Pharmaceuticals, Inc. | Antibodies for the treatment of Clostridium difficile-associated infection and disease |
| EP2632949B1 (en) * | 2010-10-25 | 2017-09-13 | National Research Council of Canada | Clostridium difficile-specific antibodies and uses thereof |
| US9815889B2 (en) * | 2011-08-02 | 2017-11-14 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. | Antibodies for prevention and treatment of diseases caused by clostridium difficile |
| PL2758432T3 (pl) * | 2011-09-16 | 2019-08-30 | Ucb Biopharma Sprl | Przeciwciała neutralizujące przeciw głównym egzotoksynom tcda i tcdb z clostridium difficile |
| UA112203C2 (uk) * | 2011-11-11 | 2016-08-10 | Юсб Фарма С.А. | Злитий білок біоспецифічного антитіла, який зв'язується з ox40 людини та сироватковим альбуміном людини |
| WO2014061783A1 (ja) * | 2012-10-19 | 2014-04-24 | 株式会社イーベック | クロストリジウム・ディフィシルの毒素に特異的なヒト抗体もしくはその抗原結合性断片 |
| GB201411320D0 (en) * | 2014-06-25 | 2014-08-06 | Ucb Biopharma Sprl | Antibody construct |
| GB201411420D0 (en) * | 2014-06-26 | 2014-08-13 | Ucb Biopharma Sprl | Antibody constructs |
| US9107906B1 (en) * | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
-
2012
- 2012-09-10 PL PL12761789T patent/PL2758432T3/pl unknown
- 2012-09-10 CN CN201280049537.6A patent/CN103958544B/zh not_active Expired - Fee Related
- 2012-09-10 HK HK14113105.9A patent/HK1199463A1/xx unknown
- 2012-09-10 PT PT12761789T patent/PT2758432T/pt unknown
- 2012-09-10 JP JP2014530307A patent/JP6152107B2/ja not_active Expired - Fee Related
- 2012-09-10 US US14/344,637 patent/US10752676B2/en not_active Expired - Fee Related
- 2012-09-10 SI SI201231613T patent/SI2758432T1/sl unknown
- 2012-09-10 HU HUE12761789A patent/HUE043661T2/hu unknown
- 2012-09-10 EP EP12761789.2A patent/EP2758432B1/en active Active
- 2012-09-10 HR HRP20190917TT patent/HRP20190917T1/hr unknown
- 2012-09-10 MX MX2014002769A patent/MX2014002769A/es unknown
- 2012-09-10 BR BR112014006175-0A patent/BR112014006175B1/pt not_active IP Right Cessation
- 2012-09-10 KR KR1020147010064A patent/KR20140063825A/ko not_active Withdrawn
- 2012-09-10 PH PH1/2014/500456A patent/PH12014500456A1/en unknown
- 2012-09-10 CN CN201810242539.6A patent/CN108424449A/zh active Pending
- 2012-09-10 EA EA201400345A patent/EA032475B1/ru not_active IP Right Cessation
- 2012-09-10 AU AU2012307157A patent/AU2012307157B2/en not_active Expired - Fee Related
- 2012-09-10 WO PCT/GB2012/052222 patent/WO2013038156A1/en not_active Ceased
- 2012-09-10 EP EP19160911.4A patent/EP3617227A3/en not_active Withdrawn
- 2012-09-10 PE PE2014000353A patent/PE20141547A1/es not_active Application Discontinuation
- 2012-09-10 SG SG11201400193SA patent/SG11201400193SA/en unknown
- 2012-09-10 LT LTEP12761789.2T patent/LT2758432T/lt unknown
- 2012-09-10 ES ES12761789T patent/ES2729278T3/es active Active
- 2012-09-10 DK DK12761789.2T patent/DK2758432T3/da active
- 2012-09-10 CA CA2848611A patent/CA2848611A1/en not_active Abandoned
- 2012-09-10 SG SG10201701055WA patent/SG10201701055WA/en unknown
-
2014
- 2014-02-26 IL IL231167A patent/IL231167A0/en unknown
- 2014-02-27 CL CL2014000491A patent/CL2014000491A1/es unknown
- 2014-03-07 TN TNP2014000101A patent/TN2014000101A1/en unknown
- 2014-04-15 CO CO14082286A patent/CO6930310A2/es unknown
- 2014-04-15 ZA ZA2014/02760A patent/ZA201402760B/en unknown
- 2014-04-16 EC ECSP14013316 patent/ECSP14013316A/es unknown
-
2017
- 2017-05-26 JP JP2017104698A patent/JP6603685B2/ja not_active Expired - Fee Related
-
2019
- 2019-06-05 CY CY20191100596T patent/CY1121673T1/el unknown
- 2019-10-11 JP JP2019187271A patent/JP2020037555A/ja not_active Ceased
-
2020
- 2020-07-02 US US16/919,576 patent/US20200377578A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA201402760B (en) | Neutralising antibodies to the major exotoxins tcda and tcdb of clostridium difficile | |
| IL237527A0 (en) | Devices and methods for growing cells | |
| IL234095B (en) | Growth of mesenchymal stem cells in culture | |
| IL236672A0 (en) | System and methods for preparing vegetable cells from animal fats | |
| DK4032586T3 (da) | Bakterieterapi til clostridium difficile-colitis | |
| EP3060650A4 (en) | Culturing pluripotent stem cells | |
| SG11201400916XA (en) | Clostridium difficile antibodies | |
| GB201205022D0 (en) | Transistors and methods for making them | |
| IL233884A0 (en) | Human antibodies to clostridium difficile toxins | |
| GB201016742D0 (en) | Clostridium difficile antigens | |
| EP2925362A4 (en) | ANTIBODIES DIRECTED AGAINST CLOSTRIDIUM DIFFICILE | |
| SG11201406301TA (en) | Clostridium difficile antigens | |
| ZA201407271B (en) | Methods and systems for sacccharification of biomass | |
| ZA201504388B (en) | Method for culturing pluripotent stem cells | |
| AP2014007559A0 (en) | Neutralising antibodies to the major exotoxins TCDA and TCDB of clostridium difficile | |
| IL231661A0 (en) | Clostridium difficile antibodies | |
| GB201103718D0 (en) | Isolation of cells |