IL220190A0 - Proteasome inhibitors and processes for their preparation, purification and use - Google Patents

Proteasome inhibitors and processes for their preparation, purification and use

Info

Publication number
IL220190A0
IL220190A0 IL220190A IL22019012A IL220190A0 IL 220190 A0 IL220190 A0 IL 220190A0 IL 220190 A IL220190 A IL 220190A IL 22019012 A IL22019012 A IL 22019012A IL 220190 A0 IL220190 A0 IL 220190A0
Authority
IL
Israel
Prior art keywords
purification
processes
preparation
proteasome inhibitors
proteasome
Prior art date
Application number
IL220190A
Other languages
English (en)
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of IL220190A0 publication Critical patent/IL220190A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL220190A 2009-12-22 2012-06-05 Proteasome inhibitors and processes for their preparation, purification and use IL220190A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28895709P 2009-12-22 2009-12-22
PCT/US2010/061695 WO2011087822A1 (en) 2009-12-22 2010-12-22 Proteasome inhibitors and processes for their preparation, purification and use

Publications (1)

Publication Number Publication Date
IL220190A0 true IL220190A0 (en) 2012-07-31

Family

ID=43530797

Family Applications (1)

Application Number Title Priority Date Filing Date
IL220190A IL220190A0 (en) 2009-12-22 2012-06-05 Proteasome inhibitors and processes for their preparation, purification and use

Country Status (10)

Country Link
US (1) US8541590B2 (https=)
EP (1) EP2516449A1 (https=)
JP (1) JP5783659B2 (https=)
CN (1) CN102725300B (https=)
AU (1) AU2010341530B2 (https=)
CA (1) CA2785300A1 (https=)
IL (1) IL220190A0 (https=)
MX (1) MX2012007341A (https=)
NZ (1) NZ600786A (https=)
WO (1) WO2011087822A1 (https=)

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KR20150067175A (ko) 2012-09-11 2015-06-17 시플라 리미티드 보르테조밉을 제조하기 위한 방법
CN103897027A (zh) * 2012-12-29 2014-07-02 曹亚英 关键中间体晶型，制备方法及其在硼替佐米合成中的运用
CN103897026A (zh) * 2012-12-29 2014-07-02 朱继东 硼替佐米关键中间体的晶型，制备方法及其运用
IN2013MU01431A (https=) 2013-04-16 2015-06-26 Cipla Ltd
CZ2015233A3 (cs) 2015-04-03 2016-10-12 Zentiva, K.S. Způsob přípravy Ixazomib citrátu
CZ2015253A3 (cs) 2015-04-15 2016-10-26 Zentiva, K.S. Nové formy Ixazomib citrátu
US10144761B2 (en) 2015-06-19 2018-12-04 Hanlin Scientific Inc. Chiral specific boron-containing compounds and their use in treating cancer or amyloidosis
CZ2016204A3 (cs) 2016-04-08 2017-11-01 Zentiva, K.S. Formulace Ixazomib citrátu formy 3
EP3583110A1 (en) 2017-02-17 2019-12-25 Fresenius Kabi Oncology Ltd An improved process for the preparation of boronic acid esters
JP7086987B2 (ja) * 2017-03-21 2022-06-20 ザ スクリプス リサーチ インスティテュート 銅およびニッケル触媒による脱炭酸ホウ素化反応
CN110540547A (zh) * 2018-05-28 2019-12-06 秦艳茹 一种肽硼酸酯类化合物的合成与用途

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JP4412586B2 (ja) 2002-01-08 2010-02-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 エポネマイシンおよびエポキソマイシン類似物およびそれらの用途
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Also Published As

Publication number Publication date
CN102725300A (zh) 2012-10-10
US20120270840A1 (en) 2012-10-25
JP2013515082A (ja) 2013-05-02
AU2010341530A1 (en) 2012-07-19
CN102725300B (zh) 2015-03-11
AU2010341530B2 (en) 2016-03-10
WO2011087822A1 (en) 2011-07-21
MX2012007341A (es) 2012-07-20
NZ600786A (en) 2013-12-20
JP5783659B2 (ja) 2015-09-24
CA2785300A1 (en) 2011-07-21
EP2516449A1 (en) 2012-10-31
US8541590B2 (en) 2013-09-24

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Legal Events

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FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees