IL196590A - History of acrylamide as inhibitors of i fab - Google Patents

History of acrylamide as inhibitors of i fab

Info

Publication number
IL196590A
IL196590A IL196590A IL19659009A IL196590A IL 196590 A IL196590 A IL 196590A IL 196590 A IL196590 A IL 196590A IL 19659009 A IL19659009 A IL 19659009A IL 196590 A IL196590 A IL 196590A
Authority
IL
Israel
Prior art keywords
fab
inhibitors
acrylamide derivatives
acrylamide
derivatives
Prior art date
Application number
IL196590A
Other languages
English (en)
Hebrew (he)
Other versions
IL196590A0 (en
Original Assignee
Debiopharm Int Sa
Affinium Pharm Inc
Debiopharma Int Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Int Sa, Affinium Pharm Inc, Debiopharma Int Sa filed Critical Debiopharm Int Sa
Publication of IL196590A0 publication Critical patent/IL196590A0/en
Publication of IL196590A publication Critical patent/IL196590A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
IL196590A 2006-07-20 2009-01-19 History of acrylamide as inhibitors of i fab IL196590A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83205806P 2006-07-20 2006-07-20
PCT/CA2007/001277 WO2008009122A1 (en) 2006-07-20 2007-07-19 Acrylamide derivatives as fab i inhibitors

Publications (2)

Publication Number Publication Date
IL196590A0 IL196590A0 (en) 2009-11-18
IL196590A true IL196590A (en) 2017-03-30

Family

ID=38956481

Family Applications (1)

Application Number Title Priority Date Filing Date
IL196590A IL196590A (en) 2006-07-20 2009-01-19 History of acrylamide as inhibitors of i fab

Country Status (6)

Country Link
US (2) US8318720B2 (https=)
EP (2) EP2687533B1 (https=)
JP (1) JP5468899B2 (https=)
CA (1) CA2658506C (https=)
IL (1) IL196590A (https=)
WO (1) WO2008009122A1 (https=)

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JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
EP2125802A4 (en) 2007-02-16 2014-08-20 Debiopharm Int Sa SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS
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WO2011061214A1 (en) 2009-11-18 2011-05-26 Fab Pharma Sas Novel heterocyclic acrylamides and their use as pharmaceuticals
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CN105503869A (zh) 2011-08-10 2016-04-20 爱尔兰詹森科学公司 抗细菌的哌啶基取代的3,4-二氢-1h-[1,8]萘啶酮
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RS61312B1 (sr) 2016-02-26 2021-02-26 Debiopharm Int Sa Lek za lečenje infekcija dijabetskog stopala
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JP7208137B2 (ja) 2016-12-09 2023-01-18 デナリ セラピューティクス インコーポレイテッド 化合物、組成物および方法
SMT202400519T1 (it) * 2018-11-12 2025-01-14 Debiopharm Int Sa Composti antibiotici. metodi di produzione degli stessi, composizioni farmaceutiche contenenti gli stessi e loro usi
TN2021000159A1 (en) 2019-02-14 2023-04-04 Debiopharm Int Sa Afabicin formulation, method for making the same and uses thereof
SG11202113174SA (en) 2019-06-14 2021-12-30 Debiopharm Int Sa Medicament and use thereof for treating bacterial infections involving biofilm
IL293980B1 (en) * 2019-12-19 2026-04-01 Debiopharm Int Sa New compounds and their use
CN112552303B (zh) * 2020-12-14 2021-11-30 承德医学院 嘧啶酮并二氮杂卓类化合物及其盐、其制备方法及医药用途
WO2022187329A1 (en) * 2021-03-03 2022-09-09 The Board Of Trustees Of The University Of Illinois Fabi inhibitors for gram-negative pathogens
TW202334164A (zh) 2022-01-12 2023-09-01 美商戴納立製藥公司 （Ｓ）－５－苄基－Ｎ－（５－甲基－４－側氧基－２，３，４，５－四氫吡啶並［３，２－ｂ］［１，４］氧氮呯－３－基）－４Ｈ－１，２，４－三唑－３－甲醯胺的晶型
WO2025248051A1 (en) 2024-05-31 2025-12-04 Debiopharm International S.A. Acrylamide derivatives for the treatment of diseases associated with pathogenic bacteria in the gastrointestinal system

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CA2658506A1 (en) 2008-01-24
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US8895545B2 (en) 2014-11-25
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