IL189361A - Doses of compounds that bind to the receptor for use in the treatment of thrombocytopenia - Google Patents

Doses of compounds that bind to the receptor for use in the treatment of thrombocytopenia

Info

Publication number
IL189361A
IL189361A IL189361A IL18936108A IL189361A IL 189361 A IL189361 A IL 189361A IL 189361 A IL189361 A IL 189361A IL 18936108 A IL18936108 A IL 18936108A IL 189361 A IL189361 A IL 189361A
Authority
IL
Israel
Prior art keywords
doses
bind
receptor
compounds
treating thrombocytopenia
Prior art date
Application number
IL189361A
Other languages
English (en)
Hebrew (he)
Other versions
IL189361A0 (en
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37734435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL189361(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of IL189361A0 publication Critical patent/IL189361A0/en
Publication of IL189361A publication Critical patent/IL189361A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL189361A 2005-08-09 2008-02-07 Doses of compounds that bind to the receptor for use in the treatment of thrombocytopenia IL189361A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/200,416 US7723295B2 (en) 2003-08-28 2005-08-09 Peptides and compounds that bind to a receptor
PCT/US2006/030359 WO2007021572A2 (en) 2005-08-09 2006-08-03 Use of peptides that bind to tpo receptor

Publications (2)

Publication Number Publication Date
IL189361A0 IL189361A0 (en) 2008-06-05
IL189361A true IL189361A (en) 2015-11-30

Family

ID=37734435

Family Applications (1)

Application Number Title Priority Date Filing Date
IL189361A IL189361A (en) 2005-08-09 2008-02-07 Doses of compounds that bind to the receptor for use in the treatment of thrombocytopenia

Country Status (34)

Country Link
US (1) US7723295B2 (enExample)
EP (1) EP1957517B1 (enExample)
JP (1) JP2009504650A (enExample)
KR (1) KR20080048026A (enExample)
CN (1) CN101287749A (enExample)
AR (1) AR055114A1 (enExample)
AU (1) AU2006280230B2 (enExample)
BR (1) BRPI0614647A2 (enExample)
CA (1) CA2618958A1 (enExample)
CR (1) CR9798A (enExample)
CY (1) CY1114032T1 (enExample)
DK (1) DK1957517T3 (enExample)
EA (1) EA200800535A1 (enExample)
EC (1) ECSP088169A (enExample)
ES (1) ES2419005T3 (enExample)
GT (1) GT200600361A (enExample)
HR (1) HRP20130518T1 (enExample)
IL (1) IL189361A (enExample)
JO (1) JO2859B1 (enExample)
MY (1) MY152177A (enExample)
NI (1) NI200800040A (enExample)
NO (1) NO344405B1 (enExample)
NZ (1) NZ565497A (enExample)
PE (1) PE20070416A1 (enExample)
PL (1) PL1957517T3 (enExample)
PT (1) PT1957517E (enExample)
RS (1) RS52802B (enExample)
SI (1) SI1957517T1 (enExample)
SV (1) SV2008002648A (enExample)
TW (1) TWI400081B (enExample)
UA (1) UA96418C2 (enExample)
UY (1) UY29736A1 (enExample)
WO (1) WO2007021572A2 (enExample)
ZA (1) ZA200802184B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
CA2499625A1 (en) * 2002-09-18 2004-04-01 Ortho-Mcneil Pharmaceutical, Inc. Methods of increasing platelet and hematopoietic stem cell production
US20040149235A1 (en) * 2002-10-04 2004-08-05 Pogue Albert S. Apparatus and method for removal of waste from animal production facilities
US7615533B2 (en) * 2004-08-16 2009-11-10 Janssen Pharmaceutica N.V. TPO peptide compounds for treatment of anemia
EP1986677A2 (en) * 2006-01-25 2008-11-05 Amgen Inc. Thrombopoietic compounds
JP2011523661A (ja) * 2008-06-03 2011-08-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 癌治療に関連する血液学的疾患を予防するためのｔｐｏ模倣ペプチド
JP5709113B2 (ja) 2011-06-23 2015-04-30 株式会社島津製作所 分岐型両親媒性ブロックポリマー、それを用いた分子集合体及び薬剤搬送システム
BR112020001367A2 (pt) 2017-07-26 2020-08-11 Janssen Pharmaceutica N.V. métodos de proteção da integridade vascular induzida por terapia de radiação direcionada
CA3127458A1 (en) 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
JP2022523295A (ja) 2019-01-25 2022-04-22 ヤンセン ファーマシューティカ エヌ．ベー． 発疱剤および苛性ガスの毒性作用を緩和する方法
WO2020154585A1 (en) 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods for mitigating liver injury and promoting liver hypertrophy, regeneration and cell engraftment in conjunction with radiation and/or radiomimetic treatments
EP4340890A4 (en) * 2021-02-24 2025-11-19 Purdue Research Foundation Osteotropic Compositions and Their Uses
JP2024536246A (ja) 2021-10-01 2024-10-04 ヤンセン ファーマシューティカ エヌ．ベー． 前駆細胞産生を増加させる方法
WO2024095178A1 (en) 2022-11-01 2024-05-10 Janssen Pharmaceutica Nv Thrombopoietin mimetic for use in the treatment of acute liver failure

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5326558A (en) 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
IL96477A0 (en) 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
DK167813B1 (da) 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US5571508A (en) 1989-12-18 1996-11-05 Amrad Corporation Limited Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor
IT1241395B (it) 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
US5141851A (en) 1990-04-18 1992-08-25 Board Of Regents, The University Of Texas System Isolated farnesyl protein transferase enzyme
US5250732A (en) 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
US5270170A (en) 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
ES2181691T5 (es) 1992-06-11 2007-10-01 Alkermes Controlled Therapeutics, Inc. Sistema de distribucion de proteina eritropoyetina.
US5358934A (en) 1992-12-11 1994-10-25 The United States Of America As Represented By The Secretary Of Agriculture Materials and methods for control of pests
WO1995011922A1 (en) 1993-10-29 1995-05-04 Affymax Technologies N.V. In vitro peptide and antibody display libraries
SG47030A1 (en) 1994-01-03 1998-03-20 Genentech Inc Thrombopoietin
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
AU1843595A (en) 1994-02-14 1995-08-29 University Of Washington Methods for stimulating erythropoiesis using thrombopoietin
EP0668352A1 (en) 1994-02-14 1995-08-23 Kirin Brewery Company, Ltd. Protein having TPO activity
NZ271230A (en) 1994-02-14 1998-03-25 Zymogenetics Inc Hematopoietic proteins, production and use
DE69503849T2 (de) 1994-03-31 1999-04-01 Amgen Inc., Thousand Oaks, Calif. Zusammensetzungen und Verfahren zur Anregung des Wachstums und der Differenzierung von Megakaryozyten
US5571686A (en) 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets
AU4163196A (en) 1994-11-30 1996-06-19 Zymogenetics Inc. Low molecular weight thrombopoietin
WO1996034016A1 (en) 1995-04-26 1996-10-31 Kyowa Hakko Kogyo Co., Ltd. Novel polypeptides
US5869451A (en) 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
EA001220B1 (ru) 1995-06-07 2000-12-25 Глаксо Груп Лимитед Пептид или пептидомиметик, который связывается с рецептором тромбоэтина, фармацевтическая композиция и способ лечения
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6060052A (en) 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5932546A (en) 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
JP2003509462A (ja) 1999-09-24 2003-03-11 スミスクライン・ビーチャム・コーポレイション トロンボポイエチン模倣物
WO2002078612A2 (en) 2001-04-02 2002-10-10 Euro-Celtique S.A. Thrombopoietin (tpo) synthebody for stimulation of platelet production
CA2499625A1 (en) 2002-09-18 2004-04-01 Ortho-Mcneil Pharmaceutical, Inc. Methods of increasing platelet and hematopoietic stem cell production
UA82710C2 (uk) 2003-08-28 2008-05-12 Орто-Макнейл Фармацевтикал, Инк. Пептид, що зв'язується з тромбопоетиновим рецептором (варіанти), та спосіб лікування тромбоциторенії (варіанти)

Also Published As

Publication number Publication date
HK1123811A1 (en) 2009-06-26
WO2007021572A2 (en) 2007-02-22
JO2859B1 (en) 2015-03-15
US7723295B2 (en) 2010-05-25
US20060040866A1 (en) 2006-02-23
CA2618958A1 (en) 2007-02-22
ES2419005T3 (es) 2013-08-19
NZ565497A (en) 2011-10-28
DK1957517T3 (da) 2013-04-08
UY29736A1 (es) 2006-12-29
CY1114032T1 (el) 2016-07-27
HRP20130518T1 (hr) 2013-07-31
UA96418C2 (ru) 2011-11-10
TWI400081B (zh) 2013-07-01
RS52802B (sr) 2013-10-31
SV2008002648A (es) 2008-11-28
PT1957517E (pt) 2013-05-28
PL1957517T3 (pl) 2013-08-30
AU2006280230A1 (en) 2007-02-22
TW200744626A (en) 2007-12-16
NO344405B1 (no) 2019-12-02
KR20080048026A (ko) 2008-05-30
SI1957517T1 (sl) 2013-07-31
CN101287749A (zh) 2008-10-15
NI200800040A (es) 2010-11-25
BRPI0614647A2 (pt) 2011-04-12
PE20070416A1 (es) 2007-06-13
EP1957517A2 (en) 2008-08-20
CR9798A (es) 2008-09-09
ECSP088169A (es) 2008-03-26
AR055114A1 (es) 2007-08-08
MY152177A (en) 2014-08-15
AU2006280230B2 (en) 2012-11-08
EA200800535A1 (ru) 2008-08-29
IL189361A0 (en) 2008-06-05
WO2007021572A3 (en) 2007-06-07
GT200600361A (es) 2007-03-14
EP1957517B1 (en) 2013-03-20
NO20081298L (no) 2008-04-23
JP2009504650A (ja) 2009-02-05
ZA200802184B (en) 2009-08-26

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