IL179171A - Inodolo [b – 3,2] Process for the preparation of quinoxylins converted into alkyl, and pharmaceutical preparations containing them - Google Patents

Inodolo [b – 3,2] Process for the preparation of quinoxylins converted into alkyl, and pharmaceutical preparations containing them

Info

Publication number
IL179171A
IL179171A IL179171A IL17917106A IL179171A IL 179171 A IL179171 A IL 179171A IL 179171 A IL179171 A IL 179171A IL 17917106 A IL17917106 A IL 17917106A IL 179171 A IL179171 A IL 179171A
Authority
IL
Israel
Prior art keywords
formula
indolo
quinoxaline
dimethyl
chloro
Prior art date
Application number
IL179171A
Other languages
English (en)
Hebrew (he)
Other versions
IL179171A0 (en
Original Assignee
Oxypharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxypharma Ab filed Critical Oxypharma Ab
Publication of IL179171A0 publication Critical patent/IL179171A0/en
Publication of IL179171A publication Critical patent/IL179171A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
IL179171A 2004-06-17 2006-11-09 Inodolo [b – 3,2] Process for the preparation of quinoxylins converted into alkyl, and pharmaceutical preparations containing them IL179171A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0401555A SE527639C2 (sv) 2004-06-17 2004-06-17 Alkylsubstituerade indolokinoxaliner
PCT/SE2005/000718 WO2005123741A1 (en) 2004-06-17 2005-05-18 Alkyl substituted indoloquinoxalines

Publications (2)

Publication Number Publication Date
IL179171A0 IL179171A0 (en) 2007-03-08
IL179171A true IL179171A (en) 2012-12-31

Family

ID=32710074

Family Applications (1)

Application Number Title Priority Date Filing Date
IL179171A IL179171A (en) 2004-06-17 2006-11-09 Inodolo [b – 3,2] Process for the preparation of quinoxylins converted into alkyl, and pharmaceutical preparations containing them

Country Status (23)

Country Link
US (2) US7589093B2 (no)
EP (1) EP1756111B1 (no)
JP (1) JP5038891B2 (no)
CN (1) CN1976934B (no)
AT (1) ATE462707T1 (no)
AU (1) AU2005254919B2 (no)
BR (1) BRPI0512086A (no)
CA (1) CA2568592C (no)
CY (1) CY1110145T1 (no)
DE (1) DE602005020283D1 (no)
DK (1) DK1756111T3 (no)
ES (1) ES2342946T3 (no)
IL (1) IL179171A (no)
MX (1) MXPA06014170A (no)
NO (1) NO20070289L (no)
NZ (1) NZ551780A (no)
PL (1) PL1756111T3 (no)
PT (1) PT1756111E (no)
RU (1) RU2369609C2 (no)
SE (1) SE527639C2 (no)
SI (1) SI1756111T1 (no)
WO (1) WO2005123741A1 (no)
ZA (1) ZA200700358B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE529777C2 (sv) * 2006-01-23 2007-11-20 Vironova Ab Nya föreningar och användning därav
JP5454750B2 (ja) 2008-03-05 2014-03-26 東洋製罐株式会社 缶詰の内圧検査方法及びその装置
EP2128160B1 (en) 2008-04-30 2010-07-14 Universität Duisburg-Essen Indolo[2,3-b]-, Indeno[1,2-b]- and Indeno[2,1-b]pyrido[2,3-f] quinoxaline-3-carboxylic acids and esters, processes for their preparation and their use as antiviral, antibiotic and antitumor agents
EP2489354A1 (en) * 2011-02-18 2012-08-22 Vironova AB Pharmaceutical formulation of B220 for topical treatment of herpes
CN103211960B (zh) * 2012-01-18 2017-10-13 金士力佳友(天津)有限公司 具有降血糖作用的中药组合物、其应用及制备方法
SG11201507310VA (en) * 2013-03-15 2015-10-29 Vironova Herpes Ab Antiviral indolo[2,3-b]quinoxaline
WO2021250196A1 (en) 2020-06-10 2021-12-16 Cyxone Ab New use of rabeximod
JP2023529877A (ja) 2020-06-10 2023-07-12 シクソン エービー 結晶形のラベキシモドの調製方法
US20230381174A1 (en) 2020-09-21 2023-11-30 Vironova Thionationl AB Thionoester-derivative of rabeximod for the treatment of inflammatory and autoimmune disorders
US11643415B1 (en) 2021-12-09 2023-05-09 Cyxone Ab Rabeximod compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE504862C2 (sv) * 1994-12-27 1997-05-20 Leif J I Lundblad Användning av vissa indolo-§2,3b¤-kinoxaliner för framställning av ett läkemedel för skydd av DNA i initieringsfasen och/eller promotionsfasen av karcinogenes och för förhindrande av oxidativ stress i patienter med sjukdomar relaterade till fria radikaler
SE516067C2 (sv) * 2000-02-18 2001-11-12 Lundblad Leif J I Användning av en förening för framställning av ett läkemedel
US6333327B2 (en) * 2000-02-18 2001-12-25 Leif J. I. Lundblad Method for the treatment of Multiple Sclerosis

Also Published As

Publication number Publication date
RU2007101497A (ru) 2008-07-27
PT1756111E (pt) 2010-06-01
AU2005254919B2 (en) 2011-07-21
EP1756111A1 (en) 2007-02-28
US20110086859A9 (en) 2011-04-14
ATE462707T1 (de) 2010-04-15
US7589093B2 (en) 2009-09-15
DK1756111T3 (da) 2010-07-12
ES2342946T3 (es) 2010-07-19
IL179171A0 (en) 2007-03-08
US20050288296A1 (en) 2005-12-29
ZA200700358B (en) 2008-07-30
NO20070289L (no) 2007-01-16
BRPI0512086A (pt) 2008-02-06
US8084453B2 (en) 2011-12-27
NZ551780A (en) 2010-05-28
WO2005123741A1 (en) 2005-12-29
SE0401555D0 (sv) 2004-06-17
CN1976934A (zh) 2007-06-06
SI1756111T1 (sl) 2010-08-31
CY1110145T1 (el) 2015-01-14
SE527639C2 (sv) 2006-05-02
MXPA06014170A (es) 2007-05-09
AU2005254919A1 (en) 2005-12-29
JP5038891B2 (ja) 2012-10-03
PL1756111T3 (pl) 2010-08-31
CA2568592C (en) 2012-10-30
DE602005020283D1 (de) 2010-05-12
RU2369609C2 (ru) 2009-10-10
CN1976934B (zh) 2013-05-29
CA2568592A1 (en) 2005-12-29
JP2008502676A (ja) 2008-01-31
US20100009999A1 (en) 2010-01-14
SE0401555L (sv) 2005-12-18
EP1756111B1 (en) 2010-03-31

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Legal Events

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FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees