IL163849A0 - Stable pharmaceutical compositions containing factor VIII - Google Patents
Stable pharmaceutical compositions containing factor VIIIInfo
- Publication number
- IL163849A0 IL163849A0 IL16384903A IL16384903A IL163849A0 IL 163849 A0 IL163849 A0 IL 163849A0 IL 16384903 A IL16384903 A IL 16384903A IL 16384903 A IL16384903 A IL 16384903A IL 163849 A0 IL163849 A0 IL 163849A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- factor viii
- stable pharmaceutical
- containing factor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0207092.8A GB0207092D0 (en) | 2002-03-26 | 2002-03-26 | Stable pharmaceutical composition containing factor VIII |
| PCT/GB2003/001297 WO2003080108A1 (en) | 2002-03-26 | 2003-03-26 | Stable pharmaceutical composition containing factor viii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL163849A0 true IL163849A0 (en) | 2005-12-18 |
Family
ID=9933726
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16384903A IL163849A0 (en) | 2002-03-26 | 2003-03-26 | Stable pharmaceutical compositions containing factor VIII |
| IL163849A IL163849A (en) | 2002-03-26 | 2004-08-31 | Stable pharmaceutical compositions containing factor viii and a liquid pharmaceutical composition obtained therefrom |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL163849A IL163849A (en) | 2002-03-26 | 2004-08-31 | Stable pharmaceutical compositions containing factor viii and a liquid pharmaceutical composition obtained therefrom |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7790680B2 (pl) |
| EP (2) | EP2292216A3 (pl) |
| JP (4) | JP2005530714A (pl) |
| KR (1) | KR20040093482A (pl) |
| CN (2) | CN103006540B (pl) |
| AR (1) | AR039123A1 (pl) |
| AT (1) | ATE477814T1 (pl) |
| AU (1) | AU2003217030B2 (pl) |
| BR (1) | BR0308442A (pl) |
| CA (1) | CA2480226C (pl) |
| DE (1) | DE60333825D1 (pl) |
| DK (1) | DK1490095T3 (pl) |
| ES (1) | ES2350337T3 (pl) |
| GB (1) | GB0207092D0 (pl) |
| HK (2) | HK1080713A1 (pl) |
| HR (1) | HRP20040882B1 (pl) |
| IL (2) | IL163849A0 (pl) |
| IS (1) | IS7458A (pl) |
| MX (1) | MXPA04009275A (pl) |
| MY (1) | MY149831A (pl) |
| NO (1) | NO328450B1 (pl) |
| NZ (1) | NZ535032A (pl) |
| PL (1) | PL208009B1 (pl) |
| PT (1) | PT1490095E (pl) |
| RU (1) | RU2314825C2 (pl) |
| TW (1) | TWI285106B (pl) |
| WO (1) | WO2003080108A1 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7560107B2 (en) | 1996-06-26 | 2009-07-14 | Emory University | Modified factor VIII |
| KR20050083841A (ko) * | 2002-10-29 | 2005-08-26 | 알자 코포레이션 | 안정화된 고체상태 폴리펩타이드 입자 |
| US7485291B2 (en) | 2003-06-03 | 2009-02-03 | Cell Genesys, Inc. | Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof |
| US7498024B2 (en) | 2003-06-03 | 2009-03-03 | Cell Genesys, Inc. | Compositions and methods for enhanced expression of immunoglobulins from a single vector using a peptide cleavage site |
| AU2004288854B2 (en) * | 2003-11-10 | 2009-10-01 | Arriva-Pharmaceuticals, Inc. | Dry recombinant human alpha 1-antitrypsin formulation |
| SI1750733T1 (sl) * | 2004-05-03 | 2014-03-31 | Emory University | POSTOPEK DAJANJA PRAĹ IÄŚJEGA fVIII BREZ DOMENE B |
| KR101710471B1 (ko) * | 2008-04-21 | 2017-02-27 | 노보 노르디스크 헬스 케어 악티엔게젤샤프트 | 건조한 트랜스글루타미나제 조성물 |
| EP2113564A1 (en) | 2008-05-01 | 2009-11-04 | Arecor Limited | Protein formulation |
| MX2011001624A (es) | 2008-08-21 | 2011-03-28 | Octapharma Ag | Factor viii y ix humano producido en forma recombinante. |
| SI2337580T1 (sl) * | 2008-09-03 | 2012-06-29 | Octapharma Ag | Stabilizirani sestavki za rekombinanto proizveden faktor VIII |
| AU2009313325B2 (en) * | 2008-11-07 | 2014-05-01 | Takeda Pharmaceutical Company Limited | Factor VIII formulations |
| GB0915480D0 (en) * | 2009-09-04 | 2009-10-07 | Arecor Ltd | Stable formulation of factor viii |
| CA2816575C (en) | 2010-11-05 | 2019-06-11 | Baxter Healthcare S.A. | A new variant of antihemophilic factor viii having increased specific activity |
| ES2926798T3 (es) | 2013-03-15 | 2022-10-28 | Bioverativ Therapeutics Inc | Formulaciones de polipéptido de factor VIII |
| RU2015144076A (ru) * | 2013-03-15 | 2017-04-24 | БАЙЕР ХелсКер ЛЛСи | Композиции рекомбинантного фактора viii |
| MX2017000862A (es) | 2014-08-04 | 2017-05-01 | Csl Ltd | Formulacion de factor viii. |
| JP6781508B2 (ja) * | 2014-11-18 | 2020-11-04 | 塩野義製薬株式会社 | 安定化されたペプチド組成物 |
| KR20220029733A (ko) | 2019-07-04 | 2022-03-08 | 체에스엘 베링 렝나우 아게 | 응고 인자 viii의 시험관내 안정성을 증가시키기 위한 절단된 폰 빌레브란트 인자 (vwf) |
| US20220380439A1 (en) | 2020-11-09 | 2022-12-01 | Takeda Pharmaceutical Company Limited | Purification of fviii from plasma using silicon oxide adsorption |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6281327A (ja) * | 1985-10-04 | 1987-04-14 | Green Cross Corp:The | 人トロンビン製剤の加熱処理方法 |
| JPS6485927A (en) | 1987-09-29 | 1989-03-30 | Green Cross Corp | Hepatitis b vaccine |
| US5605884A (en) | 1987-10-29 | 1997-02-25 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Factor VIII formulations in high ionic strength media |
| WO1989009784A1 (en) * | 1988-04-08 | 1989-10-19 | Commonwealth Serum Laboratories Commission | Production of heat-stable factor viii concentrate |
| SE465222C5 (sv) | 1989-12-15 | 1998-02-10 | Pharmacia & Upjohn Ab | Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning |
| IE64738B1 (en) * | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
| DE4111393A1 (de) | 1991-04-09 | 1992-10-15 | Behringwerke Ag | Stabilisierte faktor viii-praeparationen |
| CA2124690C (en) | 1992-10-02 | 2007-09-11 | Thomas Osterberg | Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer |
| SE9301581D0 (sv) | 1993-05-07 | 1993-05-07 | Kabi Pharmacia Ab | Protein formulation |
| SE504074C2 (sv) | 1993-07-05 | 1996-11-04 | Pharmacia Ab | Proteinberedning för subkutan, intramuskulär eller intradermal administrering |
| ZA955642B (en) * | 1994-07-07 | 1997-05-06 | Ortho Pharma Corp | Lyophilized imaging agent formulation |
| JPH0899999A (ja) * | 1994-09-30 | 1996-04-16 | Chemo Sero Therapeut Res Inst | α１プロテアーゼインヒビターの製造方法 |
| US6458563B1 (en) * | 1996-06-26 | 2002-10-01 | Emory University | Modified factor VIII |
| US5763401A (en) | 1996-07-12 | 1998-06-09 | Bayer Corporation | Stabilized albumin-free recombinant factor VIII preparation having a low sugar content |
| DK2130554T3 (da) * | 1999-02-22 | 2012-12-03 | Univ Connecticut | Albuminfrie faktor VIII-præparater |
| AU780415B2 (en) | 1999-07-13 | 2005-03-17 | Biovitrum Ab | Stable Factor VIII compositions |
| US6586574B1 (en) * | 1999-08-17 | 2003-07-01 | Nn A/S | Stabilization of freeze-dried cake |
| DE60009926T2 (de) * | 1999-08-17 | 2005-04-07 | Novo Nordisk Health Care Ag | Stabilisierung von gefriergetrocknetem kuchen |
| US7282562B2 (en) * | 1999-08-31 | 2007-10-16 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
-
2002
- 2002-03-26 GB GBGB0207092.8A patent/GB0207092D0/en not_active Ceased
-
2003
- 2003-03-14 TW TW092105665A patent/TWI285106B/zh not_active IP Right Cessation
- 2003-03-19 MY MYPI20030960A patent/MY149831A/en unknown
- 2003-03-25 AR ARP030101024A patent/AR039123A1/es not_active Application Discontinuation
- 2003-03-26 KR KR10-2004-7015295A patent/KR20040093482A/ko active Search and Examination
- 2003-03-26 PL PL372414A patent/PL208009B1/pl unknown
- 2003-03-26 ES ES03712418T patent/ES2350337T3/es not_active Expired - Lifetime
- 2003-03-26 WO PCT/GB2003/001297 patent/WO2003080108A1/en active Application Filing
- 2003-03-26 BR BR0308442-6A patent/BR0308442A/pt not_active Application Discontinuation
- 2003-03-26 DE DE60333825T patent/DE60333825D1/de not_active Expired - Lifetime
- 2003-03-26 CN CN201210563117.1A patent/CN103006540B/zh not_active Expired - Lifetime
- 2003-03-26 CN CN038069911A patent/CN1642570B/zh not_active Expired - Lifetime
- 2003-03-26 EP EP10172869A patent/EP2292216A3/en not_active Withdrawn
- 2003-03-26 NZ NZ535032A patent/NZ535032A/xx not_active IP Right Cessation
- 2003-03-26 IL IL16384903A patent/IL163849A0/xx unknown
- 2003-03-26 US US10/507,956 patent/US7790680B2/en not_active Expired - Lifetime
- 2003-03-26 AT AT03712418T patent/ATE477814T1/de active
- 2003-03-26 CA CA2480226A patent/CA2480226C/en not_active Expired - Lifetime
- 2003-03-26 RU RU2004131556/15A patent/RU2314825C2/ru active
- 2003-03-26 JP JP2003577934A patent/JP2005530714A/ja active Pending
- 2003-03-26 AU AU2003217030A patent/AU2003217030B2/en not_active Expired
- 2003-03-26 MX MXPA04009275A patent/MXPA04009275A/es active IP Right Grant
- 2003-03-26 EP EP03712418A patent/EP1490095B1/en not_active Expired - Lifetime
- 2003-03-26 DK DK03712418.7T patent/DK1490095T3/da active
- 2003-03-26 PT PT03712418T patent/PT1490095E/pt unknown
-
2004
- 2004-08-31 IL IL163849A patent/IL163849A/en not_active IP Right Cessation
- 2004-09-17 IS IS7458A patent/IS7458A/is unknown
- 2004-09-24 HR HRP20040882AA patent/HRP20040882B1/hr not_active IP Right Cessation
- 2004-10-11 NO NO20044305A patent/NO328450B1/no not_active IP Right Cessation
-
2006
- 2006-01-13 HK HK06100540.9A patent/HK1080713A1/xx not_active IP Right Cessation
-
2011
- 2011-01-07 JP JP2011002185A patent/JP2011079862A/ja active Pending
-
2013
- 2013-04-16 JP JP2013085801A patent/JP5770775B2/ja not_active Expired - Lifetime
- 2013-09-24 HK HK13110894.1A patent/HK1183446A1/xx not_active IP Right Cessation
-
2015
- 2015-03-18 JP JP2015055071A patent/JP2015143245A/ja active Pending
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