IL163827A0 - Process for synthesizing chiral n-aryl piperazines - Google Patents

Process for synthesizing chiral n-aryl piperazines

Info

Publication number
IL163827A0
IL163827A0 IL16382703A IL16382703A IL163827A0 IL 163827 A0 IL163827 A0 IL 163827A0 IL 16382703 A IL16382703 A IL 16382703A IL 16382703 A IL16382703 A IL 16382703A IL 163827 A0 IL163827 A0 IL 163827A0
Authority
IL
Israel
Prior art keywords
synthesizing chiral
aryl piperazines
piperazines
aryl
chiral
Prior art date
Application number
IL16382703A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of IL163827A0 publication Critical patent/IL163827A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL16382703A 2002-03-12 2003-03-10 Process for synthesizing chiral n-aryl piperazines IL163827A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36343102P 2002-03-12 2002-03-12
PCT/US2003/007078 WO2003078417A1 (en) 2002-03-12 2003-03-10 Process for synthesizing chiral n-aryl piperazines

Publications (1)

Publication Number Publication Date
IL163827A0 true IL163827A0 (en) 2005-12-18

Family

ID=28041762

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16382703A IL163827A0 (en) 2002-03-12 2003-03-10 Process for synthesizing chiral n-aryl piperazines

Country Status (23)

Country Link
US (1) US6713626B2 (de)
EP (1) EP1483255B1 (de)
JP (1) JP4391241B2 (de)
KR (1) KR20040105765A (de)
CN (2) CN1982307A (de)
AR (1) AR038930A1 (de)
AT (1) ATE439356T1 (de)
AU (1) AU2003220094B2 (de)
BR (1) BR0308377A (de)
CA (1) CA2477892C (de)
CR (1) CR7431A (de)
DE (1) DE60328756D1 (de)
EC (1) ECSP045290A (de)
ES (1) ES2329122T3 (de)
IL (1) IL163827A0 (de)
MX (1) MXPA04008729A (de)
NO (1) NO20044050L (de)
NZ (1) NZ535168A (de)
RU (1) RU2315762C2 (de)
TW (1) TW200403231A (de)
UA (1) UA79273C2 (de)
WO (1) WO2003078417A1 (de)
ZA (1) ZA200408202B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060287335A1 (en) * 2000-11-28 2006-12-21 Wyeth Serotonergic agents for treating sexual dysfunction
US20060223824A1 (en) * 2000-11-28 2006-10-05 Wyeth Serotonergic agents
ES2323451T7 (es) 2001-07-20 2011-08-01 Psychogenics Inc. Tratamiento para el trastorno de hiperactividad con deficit de atencion.
US7091349B2 (en) * 2002-03-12 2006-08-15 Wyeth Process for synthesizing N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane substitution
EP1483256A2 (de) * 2002-03-12 2004-12-08 Wyeth Verfahren zur herstellung chiraler 1,4-disubstituierter piperazine
IL163829A0 (en) * 2002-03-12 2005-12-18 Wyeth Corp Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines
US7361773B2 (en) * 2002-03-12 2008-04-22 Wyeth Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines
PA8626301A1 (es) * 2004-03-19 2006-12-07 Wyeth Wyeth Proceso para preparar derivados de n-aril-piperazina
US20050215561A1 (en) * 2004-03-19 2005-09-29 Krishnendu Ghosh Pharmaceutical dosage forms and compositions
US20070099931A1 (en) * 2004-03-19 2007-05-03 Wyeth Pharmaceutical dosage forms and compositions
CA2599588A1 (en) * 2005-03-01 2006-09-08 Wyeth Crystalline and amorphous 4-cyano-n{(2r)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-n-pyridin-2-yl-benzamide hydrochloride

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE81975T1 (de) 1984-12-21 1992-11-15 Duphar Int Res Arzneimittel mit psychotroper wirkung.
JPH01125357A (ja) 1987-11-06 1989-05-17 Dainippon Pharmaceut Co Ltd トリペプチドの誘導体
MX9201991A (es) * 1991-05-02 1992-11-01 Jonh Wyeth & Brother Limited Derivados de piperazina y procedimiento para su preparacion.
WO1994024115A1 (en) 1993-04-16 1994-10-27 Santen Pharmaceutical Co., Ltd. Novel piperazine derivative
GB9411099D0 (en) * 1994-06-03 1994-07-27 Wyeth John & Brother Ltd Piperazine derivatives
EP0763024B1 (de) 1994-06-03 2002-08-14 JOHN WYETH & BROTHER LIMITED Verfahren und zwischenprodukte zur herstellung von piperazinderivaten
GB9413772D0 (en) * 1994-07-08 1994-08-24 Wyeth John & Brother Ltd 5-HT1A ligands
GB9514901D0 (en) * 1995-07-20 1995-09-20 American Home Prod Piperazine derivatives
JP2000508319A (ja) 1996-04-10 2000-07-04 メルク エンド カンパニー インコーポレーテッド αｖβ３拮抗薬
US6469007B2 (en) 2000-11-28 2002-10-22 Wyeth Serotonergic agents

Also Published As

Publication number Publication date
CN1642936A (zh) 2005-07-20
RU2004130300A (ru) 2005-04-10
AU2003220094B2 (en) 2009-04-23
CA2477892A1 (en) 2003-09-25
CA2477892C (en) 2010-11-23
UA79273C2 (en) 2007-06-11
RU2315762C2 (ru) 2008-01-27
ECSP045290A (es) 2004-10-26
DE60328756D1 (de) 2009-09-24
US20030187265A1 (en) 2003-10-02
KR20040105765A (ko) 2004-12-16
WO2003078417A1 (en) 2003-09-25
MXPA04008729A (es) 2005-07-13
NO20044050L (no) 2004-09-24
US6713626B2 (en) 2004-03-30
AU2003220094A1 (en) 2003-09-29
CR7431A (es) 2008-07-29
EP1483255B1 (de) 2009-08-12
TW200403231A (en) 2004-03-01
AR038930A1 (es) 2005-02-02
BR0308377A (pt) 2005-01-11
NZ535168A (en) 2006-03-31
ES2329122T3 (es) 2009-11-23
ZA200408202B (en) 2007-03-28
ATE439356T1 (de) 2009-08-15
CN1304388C (zh) 2007-03-14
JP4391241B2 (ja) 2009-12-24
JP2005526775A (ja) 2005-09-08
CN1982307A (zh) 2007-06-20
EP1483255A1 (de) 2004-12-08

Similar Documents

Publication Publication Date Title
AU2003286588A8 (en) Methods for synthesizing complementary dna
HK1078863A1 (en) Process for preparing (s)-pantoprazole
GB0504952D0 (en) Process for producing arylamine
EP1532985A4 (de) Verfahren zur herstellung einer zusammensetzung mit verz gerter freisetzung
SG137677A1 (en) Improved process for preparing polyalkenylsuccinimides
ZA200602149B (en) Process for the synthesis of 6-amino-4-[(3-chloro-4-fluo-rophenyl)amino]-7-ethoxy-quinoline-3-carbonitrile
IL163827A0 (en) Process for synthesizing chiral n-aryl piperazines
AU2003293122A8 (en) Methods for synthesizing polysaccharides
AU2003212892A1 (en) Apparatus for synthesis of radiolabeled compounds
EP1507781A4 (de) Verfahren zur herstellung von maytansinol
EP1547993A4 (de) Verfahren zur herstellung von spirofluorenolen
PL372214A1 (en) Novel process
AU2003287174A8 (en) Process for synthesizing antifolates
IL163828A0 (en) Process for making chiral 1,4-disubstituted piperazines
ZA200501601B (en) Process for producing indolopyrrolocarbazole derivative
GB2384487B (en) Improved process for synthesizing tackifier resin
EP1698703A4 (de) Verfahren zur dipeptidherstellung
AU2003246098A8 (en) Oxamidination process of carbonyl compounds
EG24122A (en) Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines
EP1539772A4 (de) Verfahren zur herstellung von phosphordiamiditverbindungen
AU2003303563A8 (en) Process for synthesizing amine from nitrile
AU2003222342A8 (en) Method for preparing $g(v)-bromoalkylcarboxylic compounds
EP1546186A4 (de) Verfahren zur synthese von peptiden
PL1654240T3 (pl) Sposób otrzymywania N-arylomorfolinonów
PL374000A1 (en) Improved process for hydroxyazapirones