IL162735A0 - Labeling targeting agents with gallium-68 and gallium-67 - Google Patents

Labeling targeting agents with gallium-68 and gallium-67

Info

Publication number
IL162735A0
IL162735A0 IL16273502A IL16273502A IL162735A0 IL 162735 A0 IL162735 A0 IL 162735A0 IL 16273502 A IL16273502 A IL 16273502A IL 16273502 A IL16273502 A IL 16273502A IL 162735 A0 IL162735 A0 IL 162735A0
Authority
IL
Israel
Prior art keywords
gallium
targeting agents
labeling targeting
labeling
agents
Prior art date
Application number
IL16273502A
Other languages
English (en)
Original Assignee
Immunomedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunomedics Inc filed Critical Immunomedics Inc
Publication of IL162735A0 publication Critical patent/IL162735A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
IL16273502A 2001-12-26 2002-12-23 Labeling targeting agents with gallium-68 and gallium-67 IL162735A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34210401P 2001-12-26 2001-12-26
PCT/GB2002/005902 WO2003059397A2 (fr) 2001-12-26 2002-12-23 Marquage d'agents de ciblage au gallium-68 et au gallium-67

Publications (1)

Publication Number Publication Date
IL162735A0 true IL162735A0 (en) 2005-11-20

Family

ID=23340342

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16273502A IL162735A0 (en) 2001-12-26 2002-12-23 Labeling targeting agents with gallium-68 and gallium-67

Country Status (12)

Country Link
US (1) US7011816B2 (fr)
EP (2) EP1465670B1 (fr)
JP (1) JP2005514444A (fr)
KR (1) KR20040068363A (fr)
AU (1) AU2002356315B2 (fr)
BR (1) BR0215461A (fr)
CA (1) CA2471817C (fr)
IL (1) IL162735A0 (fr)
MX (1) MXPA04006328A (fr)
PL (1) PL370580A1 (fr)
RU (1) RU2004122695A (fr)
WO (1) WO2003059397A2 (fr)

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US20040022726A1 (en) * 2002-06-03 2004-02-05 Goldenberg David M. Methods and compositions for intravesical therapy of bladder cancer
US7563433B2 (en) * 2007-01-11 2009-07-21 Immunomedics, Inc. Methods and compositions for F-18 labeling of proteins, peptides and other molecules
US7597876B2 (en) * 2007-01-11 2009-10-06 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
US7993626B2 (en) * 2007-01-11 2011-08-09 Immunomedics, Inc. Methods and compositions for F-18 labeling of proteins, peptides and other molecules
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JP4937751B2 (ja) * 2003-06-13 2012-05-23 イミューノメディクス、インコーポレイテッド Ｄ−アミノ酸ペプチド
CA2533878A1 (fr) 2003-07-29 2005-09-22 Immunomedics, Inc. Conjugues glucidiques fluores
DE102004057225B4 (de) * 2004-11-26 2006-10-12 Johannes-Gutenberg-Universität Mainz Verfahren und Vorrichtung zur Isolierung eines chemisch und radiochemisch gereinigten 68Ga-Radionuklids und zum Markieren eines Markierungsvorläufers mit dem 68Ga-Radionuklid
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
CA2625196C (fr) 2005-10-07 2016-04-05 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
FR2899585B1 (fr) * 2006-04-05 2012-06-15 Guerbet Sa Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
CA2654369C (fr) * 2006-06-21 2014-10-14 Ge Healthcare Limited Produits radiopharmaceutiques
WO2008026051A2 (fr) * 2006-08-29 2008-03-06 Ge Healthcare Limited Marquage par 68ga d'un chélateur macrocyclique libre et conjugué à une macromolécule à la température ambiante
US8398956B2 (en) 2007-01-11 2013-03-19 Immunomedics, Inc. In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents
US8153100B2 (en) * 2007-01-11 2012-04-10 Immunomedics, Inc. Methods and compositions for F-18 labeling of proteins, peptides and other molecules
US8709382B2 (en) 2007-01-11 2014-04-29 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
US8545809B2 (en) 2007-01-11 2013-10-01 Immunomedics, Inc. Methods and compositions for improved 18F labeling of proteins, peptides and other molecules
US8889100B2 (en) 2007-01-11 2014-11-18 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
CA2916671C (fr) * 2007-01-17 2018-01-09 Immunomedics, Inc. Supports polymeres d'agents therapeutiques et fractions de reconnaissance pour un ciblage a base d'anticorps de sites de maladie
FR2914303A1 (fr) * 2007-03-28 2008-10-03 Guerbet Sa Composes pour le diagnostic de l'apoptose.
DE102009007799B4 (de) 2009-02-06 2010-10-14 ITM Isotopen Technologien München AG Molekül zur Funktionalisierung eines Trägers, Bindung eines Radionuklids an den Träger und Radionuklidgenerator zur Herstellung des Radionuklids sowie Herstellungsverfahren
US20110318265A1 (en) * 2009-04-07 2011-12-29 Bernstein Lawrence R Coupled identification and treatment of cancer
KR100991716B1 (ko) * 2009-10-22 2010-11-04 경북대학교 산학협력단 광학영상 조영제, 그 용도 및 장치
JP5789821B2 (ja) * 2009-12-04 2015-10-07 イミューノメディクス、インコーポレイテッドＩｍｍｕｎｏｍｅｄｉｃｓ， Ｉｎｃ． タンパク質、ペプチドおよび他の分子の改善されたｆ−１８標識化のための方法および組成物
DE102010037964B3 (de) 2010-10-05 2012-03-22 ITM Isotopen Technologien München AG 68Ga-Generator
US9161998B2 (en) * 2012-05-18 2015-10-20 Zentralklinik Bad Berka Gmbh Method and kit for preparing a radiopharmaceutical
DE102012208375B4 (de) 2012-05-18 2015-07-23 Zentralklinik Bad Berka Gmbh Satz und Verfahren zur Herstellung eines Radiopharmakons
FR2998298B1 (fr) * 2012-11-21 2020-11-20 Univ Bourgogne Synthese de sels d’imidazo[1,2-a]pyrazin-4-ium pour la synthese du 1,4,7-triazacyclononane (tacn) et de ses derives n- et/ou c-fonctionnalises
CN104854126B (zh) 2012-11-30 2018-10-16 国立大学法人京都大学 多肽及成像方法
WO2015084996A1 (fr) * 2013-12-03 2015-06-11 Millennium Pharmaceuticals, Inc. Composés et compositions pour l'imagerie de cellules exprimant gcc
BE1021191B1 (fr) * 2014-08-29 2015-10-27 Anmi S.A. Kit pour radiomarquage.
US11027030B2 (en) * 2014-08-29 2021-06-08 Anmi S.A. Kit for radiolabelling
GB201504064D0 (en) * 2015-03-10 2015-04-22 Accretion Biotechnology Ltd Method and kits for preparing radionuclide complexes
RU2625271C1 (ru) * 2016-06-08 2017-07-12 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ (ФГБУ "РНЦРХТ" Минздрава России) Способ лечения резектабельных первичных местнораспространенных злокачественных нейроэндокринных опухолей головки поджелудочной железы
RU2625275C1 (ru) * 2016-06-08 2017-07-12 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ / ФГБУ "РНЦРХТ" Минздрава России Способ лечения злокачественных нейроэндокринных опухолей головки поджелудочной железы с метастазами в печень
JP7194595B2 (ja) * 2016-07-01 2022-12-22 ザ ジェネラル ホスピタル コーポレイション グランザイムｂを指向するイメージングおよび治療
TW201832750A (zh) * 2017-03-02 2018-09-16 美商５１１製藥公司 放射性藥品標記裝置
CN114149489B (zh) * 2021-11-18 2023-12-15 厦门大学 一种靶向tigit的放射性标记化合物及其制备方法和应用

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US5364613A (en) * 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
DE4009119A1 (de) * 1990-03-19 1991-09-26 Schering Ag 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5079346A (en) 1990-05-01 1992-01-07 Trustees Of The University Of Pennsylvania Gallium-labelled imaging agents
WO1994004485A1 (fr) 1992-08-19 1994-03-03 Mallinckrodt Medical, Inc. LIGANDS UTILISES DANS LA TOMOGRAPHIE CARDIAQUE A POSITONS REALISEE AVEC DU Ga-68
US5639439A (en) 1994-12-15 1997-06-17 Institute Of Nuclear Energy Research, Taiwan Gallium dimercaptosuccinate as a novel tumor imaging agent
AU4047497A (en) 1996-07-31 1998-02-20 Immunomedics Inc. Improved detection and therapy of lesions with biotin-chelate conjugates
EP1075287B1 (fr) 1998-05-07 2004-02-18 Immunomedics, Inc. Tomographie par emission de positrons mettant en oeuvre des chelates de gallium 68
US6071490A (en) * 1998-05-07 2000-06-06 Immunomedics, Inc. Position emission tomography using gallium-68 chelates
US7138103B2 (en) * 1998-06-22 2006-11-21 Immunomedics, Inc. Use of bi-specific antibodies for pre-targeting diagnosis and therapy
US20040043030A1 (en) * 2001-07-31 2004-03-04 Immunomedics, Inc. Polymeric delivery systems
WO2003048207A2 (fr) * 2001-11-28 2003-06-12 Immunomedics, Inc. Anticorps dirige contre le dota

Also Published As

Publication number Publication date
PL370580A1 (en) 2005-05-30
US20030176784A1 (en) 2003-09-18
AU2002356315B2 (en) 2008-09-04
JP2005514444A (ja) 2005-05-19
EP1465670A2 (fr) 2004-10-13
CA2471817A1 (fr) 2003-07-24
WO2003059397A3 (fr) 2003-08-28
US7011816B2 (en) 2006-03-14
RU2004122695A (ru) 2005-04-20
BR0215461A (pt) 2005-04-05
WO2003059397A2 (fr) 2003-07-24
KR20040068363A (ko) 2004-07-30
EP2311500A1 (fr) 2011-04-20
EP1465670B1 (fr) 2014-07-02
AU2002356315A1 (en) 2003-07-30
CA2471817C (fr) 2013-09-24
MXPA04006328A (es) 2005-06-08
EP2311500B1 (fr) 2015-02-25

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