BR0215461A - Rotulagem de agentes de rotulagem com gálio-68 e gálio-67 - Google Patents

Rotulagem de agentes de rotulagem com gálio-68 e gálio-67

Info

Publication number
BR0215461A
BR0215461A BR0215461-7A BR0215461A BR0215461A BR 0215461 A BR0215461 A BR 0215461A BR 0215461 A BR0215461 A BR 0215461A BR 0215461 A BR0215461 A BR 0215461A
Authority
BR
Brazil
Prior art keywords
labeling
gallium
agents
agent
macrocycle
Prior art date
Application number
BR0215461-7A
Other languages
English (en)
Inventor
Gary L Griffiths
William J Mcbride
Original Assignee
Immunomedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunomedics Inc filed Critical Immunomedics Inc
Publication of BR0215461A publication Critical patent/BR0215461A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"ROTULAGEM DE AGENTES DE ROTULAGEM COM GáLIO-68 E GáLIO-67". A presente invenção refere-se a um método e composições que são descritos para rotulagem de um agente de marcação com Ga-68, em que o eluato proveniente de um gerador de Ge-68 1 Ga-68 é combinado com um agente de marcação que contém macrociclo. O método de rotulagem e as composições descritas garantem que pode ser usada uma simples eluição de Ga-68, retirada diretamente de um gerador, sem manipulação adicional para marcar quantitativamente um agente de marcação que contém macrociclo. O agente de marcação rotulado com Ga-68 assim produzido é útil com agentes de marcação específicos e é mais especialmente útil em um método de pré-direcionamento para detecção tomográfica por emissão de pósitron.
BR0215461-7A 2001-12-26 2002-12-23 Rotulagem de agentes de rotulagem com gálio-68 e gálio-67 BR0215461A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34210401P 2001-12-26 2001-12-26
PCT/GB2002/005902 WO2003059397A2 (en) 2001-12-26 2002-12-23 Labeling targeting agents with gallium-68 and gallium-67

Publications (1)

Publication Number Publication Date
BR0215461A true BR0215461A (pt) 2005-04-05

Family

ID=23340342

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0215461-7A BR0215461A (pt) 2001-12-26 2002-12-23 Rotulagem de agentes de rotulagem com gálio-68 e gálio-67

Country Status (12)

Country Link
US (1) US7011816B2 (pt)
EP (2) EP1465670B1 (pt)
JP (1) JP2005514444A (pt)
KR (1) KR20040068363A (pt)
AU (1) AU2002356315B2 (pt)
BR (1) BR0215461A (pt)
CA (1) CA2471817C (pt)
IL (1) IL162735A0 (pt)
MX (1) MXPA04006328A (pt)
PL (1) PL370580A1 (pt)
RU (1) RU2004122695A (pt)
WO (1) WO2003059397A2 (pt)

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FR2899585B1 (fr) * 2006-04-05 2012-06-15 Guerbet Sa Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
US8926945B2 (en) 2005-10-07 2015-01-06 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
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US8889100B2 (en) 2007-01-11 2014-11-18 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
US8153100B2 (en) * 2007-01-11 2012-04-10 Immunomedics, Inc. Methods and compositions for F-18 labeling of proteins, peptides and other molecules
US8545809B2 (en) 2007-01-11 2013-10-01 Immunomedics, Inc. Methods and compositions for improved 18F labeling of proteins, peptides and other molecules
US8709382B2 (en) 2007-01-11 2014-04-29 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
US8398956B2 (en) 2007-01-11 2013-03-19 Immunomedics, Inc. In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents
CA2675014C (en) * 2007-01-17 2016-03-29 Immunomedics, Inc. Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites
FR2914303A1 (fr) * 2007-03-28 2008-10-03 Guerbet Sa Composes pour le diagnostic de l'apoptose.
DE102009007799B4 (de) * 2009-02-06 2010-10-14 ITM Isotopen Technologien München AG Molekül zur Funktionalisierung eines Trägers, Bindung eines Radionuklids an den Träger und Radionuklidgenerator zur Herstellung des Radionuklids sowie Herstellungsverfahren
US20110318265A1 (en) * 2009-04-07 2011-12-29 Bernstein Lawrence R Coupled identification and treatment of cancer
KR100991716B1 (ko) * 2009-10-22 2010-11-04 경북대학교 산학협력단 광학영상 조영제, 그 용도 및 장치
DE102010037964B3 (de) * 2010-10-05 2012-03-22 ITM Isotopen Technologien München AG 68Ga-Generator
US9161998B2 (en) * 2012-05-18 2015-10-20 Zentralklinik Bad Berka Gmbh Method and kit for preparing a radiopharmaceutical
DE102012208375B4 (de) * 2012-05-18 2015-07-23 Zentralklinik Bad Berka Gmbh Satz und Verfahren zur Herstellung eines Radiopharmakons
FR2998298B1 (fr) 2012-11-21 2020-11-20 Univ Bourgogne Synthese de sels d’imidazo[1,2-a]pyrazin-4-ium pour la synthese du 1,4,7-triazacyclononane (tacn) et de ses derives n- et/ou c-fonctionnalises
CN104854126B (zh) * 2012-11-30 2018-10-16 国立大学法人京都大学 多肽及成像方法
EP3077407A4 (en) * 2013-12-03 2017-07-19 Millennium Pharmaceuticals, Inc. Compounds and compositions for imaging gcc-expressing cells
BE1021191B1 (fr) * 2014-08-29 2015-10-27 Anmi S.A. Kit pour radiomarquage.
US11027030B2 (en) 2014-08-29 2021-06-08 Anmi S.A. Kit for radiolabelling
IL237525A (en) 2015-03-03 2017-05-29 Shalom Eli Method for labeling a prostate-specific membrane antigen with a radioactive isotope
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RU2625271C1 (ru) * 2016-06-08 2017-07-12 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ (ФГБУ "РНЦРХТ" Минздрава России) Способ лечения резектабельных первичных местнораспространенных злокачественных нейроэндокринных опухолей головки поджелудочной железы
JP7194595B2 (ja) * 2016-07-01 2022-12-22 ザ ジェネラル ホスピタル コーポレイション グランザイムｂを指向するイメージングおよび治療
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CN114149489B (zh) * 2021-11-18 2023-12-15 厦门大学 一种靶向tigit的放射性标记化合物及其制备方法和应用

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Also Published As

Publication number Publication date
US7011816B2 (en) 2006-03-14
EP1465670A2 (en) 2004-10-13
AU2002356315B2 (en) 2008-09-04
KR20040068363A (ko) 2004-07-30
WO2003059397A2 (en) 2003-07-24
IL162735A0 (en) 2005-11-20
RU2004122695A (ru) 2005-04-20
WO2003059397A3 (en) 2003-08-28
PL370580A1 (en) 2005-05-30
CA2471817C (en) 2013-09-24
EP1465670B1 (en) 2014-07-02
AU2002356315A1 (en) 2003-07-30
JP2005514444A (ja) 2005-05-19
MXPA04006328A (es) 2005-06-08
EP2311500B1 (en) 2015-02-25
CA2471817A1 (en) 2003-07-24
US20030176784A1 (en) 2003-09-18
EP2311500A1 (en) 2011-04-20

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 51/08 (2006.01), A61K 51/10 (2006.01)