IL162243A0 - Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands - Google Patents
Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligandsInfo
- Publication number
- IL162243A0 IL162243A0 IL16224302A IL16224302A IL162243A0 IL 162243 A0 IL162243 A0 IL 162243A0 IL 16224302 A IL16224302 A IL 16224302A IL 16224302 A IL16224302 A IL 16224302A IL 162243 A0 IL162243 A0 IL 162243A0
- Authority
- IL
- Israel
- Prior art keywords
- hydroxytryptamine
- ligands
- indolylalkylamine
- derivatives
- indolylalkylamine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34290701P | 2001-12-20 | 2001-12-20 | |
| PCT/US2002/040217 WO2003053433A1 (en) | 2001-12-20 | 2002-12-17 | Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL162243A0 true IL162243A0 (en) | 2005-11-20 |
Family
ID=23343804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16224302A IL162243A0 (en) | 2001-12-20 | 2002-12-17 | Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US6770642B2 (xx) |
| EP (1) | EP1455779B1 (xx) |
| JP (1) | JP4335684B2 (xx) |
| KR (1) | KR100985140B1 (xx) |
| CN (1) | CN1309385C (xx) |
| AR (1) | AR037906A1 (xx) |
| AT (1) | ATE335477T1 (xx) |
| AU (1) | AU2002357270B2 (xx) |
| BR (1) | BR0215222A (xx) |
| CA (1) | CA2470863C (xx) |
| CO (1) | CO5590924A2 (xx) |
| CY (1) | CY1105705T1 (xx) |
| DE (1) | DE60213856T2 (xx) |
| DK (1) | DK1455779T3 (xx) |
| EC (1) | ECSP045156A (xx) |
| ES (1) | ES2269827T3 (xx) |
| HK (1) | HK1065949A1 (xx) |
| HU (1) | HUP0402640A3 (xx) |
| IL (1) | IL162243A0 (xx) |
| MX (1) | MXPA04005889A (xx) |
| NO (1) | NO330338B1 (xx) |
| NZ (1) | NZ533666A (xx) |
| PL (1) | PL210413B1 (xx) |
| PT (1) | PT1455779E (xx) |
| RU (1) | RU2309157C2 (xx) |
| SI (1) | SI1455779T1 (xx) |
| TW (1) | TWI254705B (xx) |
| UA (1) | UA78536C2 (xx) |
| WO (1) | WO2003053433A1 (xx) |
| ZA (1) | ZA200405731B (xx) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7026515B2 (en) * | 2000-11-09 | 2006-04-11 | Mitsui Chemicals, Inc. | Optically active amine derivatives and preparation process therefor |
| TW200301251A (en) * | 2001-12-20 | 2003-07-01 | Wyeth Corp | Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands |
| BRPI0412809A (pt) * | 2003-07-23 | 2006-09-26 | Wyeth Corp | compostos de sulfonildihidrobenzimidazolona como ligantes a 5-hidróxitriptamina-6 |
| US20050032873A1 (en) * | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
| ATE370955T1 (de) * | 2003-07-31 | 2007-09-15 | Wyeth Corp | N-sulfonylheterocyclopyrrolylalkylamin verbindungen als 5-hydroxytryptamin-6 liganden. |
| US7511145B2 (en) * | 2003-08-01 | 2009-03-31 | Genelabs Technologies, Inc. | Bicyclic heteroaryl derivatives |
| PT1704154E (pt) * | 2004-01-02 | 2009-08-05 | Suven Life Sciences Ltd | Novos indeno[2,1a]indenos e isoindol[2,1-a]indóis |
| PE20060303A1 (es) * | 2004-06-23 | 2006-05-19 | Wyeth Corp | Metabolitos de indolilalquilamina como ligandos de 5-hidroxitriptamina-6 |
| EP1824464A1 (en) * | 2004-12-14 | 2007-08-29 | Wyeth a Corporation of the State of Delaware | Use of a 5-ht6 agonist for the treatment and prevention of neurodegenerative disorders |
| US20060211698A1 (en) * | 2005-01-14 | 2006-09-21 | Genelabs, Inc. | Bicyclic heteroaryl derivatives for treating viruses |
| EP1953153A1 (en) * | 2007-01-31 | 2008-08-06 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituted sulfonamides for the treatment of cognitive or food ingestion related disorders |
| CN101730680A (zh) * | 2007-05-24 | 2010-06-09 | 记忆医药公司 | 具有5-ht6受体亲和力的4’取代的化合物 |
| ES2359170T3 (es) * | 2007-07-19 | 2011-05-19 | Laboratorios Del Dr. Esteve S.A. | Compuestos tetrahidro-quinolín-sulfonamida sustituidos, su preparación y uso como medicamentos. |
| EP2053052A1 (en) | 2007-10-23 | 2009-04-29 | Laboratorios del Dr. Esteve S.A. | Process for the preparation of 6-substituted imidazo[2,1-b]thiazole-5-sulfonyl halide |
| JP2011505418A (ja) * | 2007-12-04 | 2011-02-24 | メルク・シャープ・エンド・ドーム・コーポレイション | ５−ｈｔ６アンタゴニストとしてのトリプタミンスルホンアミド |
| EP2236511A4 (en) | 2007-12-21 | 2011-04-13 | Alla Chem Llc | LIGANDS OF ALPHA ADRENOCEPTORS AND OF DOPAMINE, HISTAMIN, IMIDAZOLIN AND SEROTONIN RECEPTORS AND THEIR APPLICATION THEREOF |
| US20100016297A1 (en) * | 2008-06-24 | 2010-01-21 | Memory Pharmaceuticals Corporation | Alkyl-substituted 3' compounds having 5-ht6 receptor affinity |
| US20100022581A1 (en) * | 2008-07-02 | 2010-01-28 | Memory Pharmaceuticals Corporation | Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity |
| US20100029629A1 (en) * | 2008-07-25 | 2010-02-04 | Memory Pharmaceuticals Corporation | Acyclic compounds having 5-ht6 receptor affinity |
| US20100056531A1 (en) * | 2008-08-22 | 2010-03-04 | Memory Pharmaceuticals Corporation | Alkyl-substituted 3' compounds having 5-ht6 receptor affinity |
| US9663498B2 (en) | 2013-12-20 | 2017-05-30 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
| PT3186233T (pt) | 2014-08-29 | 2021-12-02 | Chdi Foundation Inc | Sondas para imagem de proteína de huntingtina |
| US10907197B2 (en) | 2014-08-29 | 2021-02-02 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5545644A (en) | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
| US6194410B1 (en) | 1998-03-11 | 2001-02-27 | Hoffman-La Roche Inc. | Pyrazolopyrimidine and pyrazolines and process for preparation thereof |
| US6133287A (en) | 1998-03-24 | 2000-10-17 | Allelix Biopharmaceuticals Inc. | Piperidine-indole compounds having 5-HT6 affinity |
| GB9820113D0 (en) | 1998-09-15 | 1998-11-11 | Merck Sharp & Dohme | Therapeutic agents |
| US6403808B1 (en) | 1999-12-10 | 2002-06-11 | Virginia Commonwealth University | Selective 5-HT6 receptor ligands |
| WO2001012629A1 (en) * | 1999-08-12 | 2001-02-22 | Nps Allelix Corp. | Azaindoles having serotonin receptor affinity |
| WO2001032660A1 (en) * | 1999-11-05 | 2001-05-10 | Nps Allelix Corp. | Compounds having 5-ht6 receptor antagonist activity |
| WO2001034146A1 (en) * | 1999-11-08 | 2001-05-17 | Smithkline Beecham Corporation | Novel anti-infectives |
-
2002
- 2002-12-17 IL IL16224302A patent/IL162243A0/xx unknown
- 2002-12-17 JP JP2003554190A patent/JP4335684B2/ja not_active Expired - Fee Related
- 2002-12-17 NZ NZ533666A patent/NZ533666A/xx not_active IP Right Cessation
- 2002-12-17 PL PL370711A patent/PL210413B1/pl not_active IP Right Cessation
- 2002-12-17 SI SI200230401T patent/SI1455779T1/sl unknown
- 2002-12-17 CN CNB028281721A patent/CN1309385C/zh not_active Expired - Fee Related
- 2002-12-17 ES ES02805601T patent/ES2269827T3/es not_active Expired - Lifetime
- 2002-12-17 BR BR0215222-3A patent/BR0215222A/pt not_active Application Discontinuation
- 2002-12-17 WO PCT/US2002/040217 patent/WO2003053433A1/en active IP Right Grant
- 2002-12-17 EP EP02805601A patent/EP1455779B1/en not_active Expired - Lifetime
- 2002-12-17 KR KR1020047009606A patent/KR100985140B1/ko not_active IP Right Cessation
- 2002-12-17 UA UA20040705919A patent/UA78536C2/uk unknown
- 2002-12-17 CA CA2470863A patent/CA2470863C/en not_active Expired - Fee Related
- 2002-12-17 PT PT02805601T patent/PT1455779E/pt unknown
- 2002-12-17 AT AT02805601T patent/ATE335477T1/de active
- 2002-12-17 HU HU0402640A patent/HUP0402640A3/hu unknown
- 2002-12-17 MX MXPA04005889A patent/MXPA04005889A/es active IP Right Grant
- 2002-12-17 DE DE60213856T patent/DE60213856T2/de not_active Expired - Lifetime
- 2002-12-17 RU RU2004122129/04A patent/RU2309157C2/ru not_active IP Right Cessation
- 2002-12-17 AU AU2002357270A patent/AU2002357270B2/en not_active Ceased
- 2002-12-17 DK DK02805601T patent/DK1455779T3/da active
- 2002-12-18 TW TW091136490A patent/TWI254705B/zh active
- 2002-12-18 AR ARP020104951A patent/AR037906A1/es unknown
- 2002-12-19 US US10/323,369 patent/US6770642B2/en not_active Expired - Fee Related
-
2004
- 2004-04-20 US US10/828,014 patent/US7022701B2/en not_active Expired - Fee Related
- 2004-06-15 CO CO04055771A patent/CO5590924A2/es not_active Application Discontinuation
- 2004-06-16 EC EC2004005156A patent/ECSP045156A/es unknown
- 2004-07-19 NO NO20043100A patent/NO330338B1/no not_active IP Right Cessation
- 2004-07-19 ZA ZA200405731A patent/ZA200405731B/en unknown
- 2004-11-10 HK HK04108844A patent/HK1065949A1/xx not_active IP Right Cessation
-
2006
- 2006-10-13 CY CY20061101474T patent/CY1105705T1/el unknown
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