IL162082A0 - Melt extrusion consisting of salts of active ingredients - Google Patents

Melt extrusion consisting of salts of active ingredients

Info

Publication number
IL162082A0
IL162082A0 IL16208203A IL16208203A IL162082A0 IL 162082 A0 IL162082 A0 IL 162082A0 IL 16208203 A IL16208203 A IL 16208203A IL 16208203 A IL16208203 A IL 16208203A IL 162082 A0 IL162082 A0 IL 162082A0
Authority
IL
Israel
Prior art keywords
active ingredient
salts
granule
meth
active ingredients
Prior art date
Application number
IL16208203A
Other languages
English (en)
Original Assignee
Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm Gmbh filed Critical Roehm Gmbh
Publication of IL162082A0 publication Critical patent/IL162082A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Seasonings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL16208203A 2002-02-27 2003-01-30 Melt extrusion consisting of salts of active ingredients IL162082A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10208344A DE10208344A1 (de) 2002-02-27 2002-02-27 Schmelzextrusion von Wirkstoffsalzen
PCT/EP2003/000935 WO2003072083A2 (de) 2002-02-27 2003-01-30 Schmelzextrusion von wirkstoffsalzen

Publications (1)

Publication Number Publication Date
IL162082A0 true IL162082A0 (en) 2005-11-20

Family

ID=27675020

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16208203A IL162082A0 (en) 2002-02-27 2003-01-30 Melt extrusion consisting of salts of active ingredients
IL162082A IL162082A (en) 2002-02-27 2004-05-20 Extrusion molten material containing salts of active ingredients and a process for its preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL162082A IL162082A (en) 2002-02-27 2004-05-20 Extrusion molten material containing salts of active ingredients and a process for its preparation

Country Status (14)

Country Link
US (1) US8642089B2 (ja)
EP (1) EP1478344B1 (ja)
JP (1) JP5054278B2 (ja)
KR (1) KR100707712B1 (ja)
AT (1) ATE362754T1 (ja)
AU (1) AU2003210196A1 (ja)
BR (1) BRPI0307995B8 (ja)
CA (1) CA2474691C (ja)
DE (2) DE10208344A1 (ja)
ES (1) ES2286447T3 (ja)
IL (2) IL162082A0 (ja)
MX (1) MXPA04008345A (ja)
PL (1) PL204465B1 (ja)
WO (1) WO2003072083A2 (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10239999A1 (de) * 2002-08-27 2004-03-04 Röhm GmbH & Co. KG Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen
DE10304403A1 (de) * 2003-01-28 2004-08-05 Röhm GmbH & Co. KG Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
JP2006028028A (ja) * 2004-07-12 2006-02-02 Teikoku Medix Kk 経口医薬組成物
AU2005320547B2 (en) 2004-12-27 2009-02-05 Eisai R & D Management Co., Ltd. Method for stabilizing anti-dementia drug
KR20080089344A (ko) * 2005-12-14 2008-10-06 에프. 호프만-라 로슈 아게 Ｃ형 간염 바이러스(ｈｃｖ) 전구약물 제형
US20100172989A1 (en) * 2006-01-21 2010-07-08 Abbott Laboratories Abuse resistant melt extruded formulation having reduced alcohol interaction
US20090317355A1 (en) * 2006-01-21 2009-12-24 Abbott Gmbh & Co. Kg, Abuse resistant melt extruded formulation having reduced alcohol interaction
DE102007009242A1 (de) * 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets mit magensaftresistenter Wirkstoff-Matix
DE102007026550A1 (de) 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
KR20100134557A (ko) * 2008-01-11 2010-12-23 씨아이피엘에이 엘티디. 고체 약제학적 투여 제형
TW200950776A (en) * 2008-01-24 2009-12-16 Abbott Gmbh & Co Kg Abuse resistant melt extruded formulation having reduced alcohol interaction
JP2011511782A (ja) 2008-02-12 2011-04-14 アボット・ラボラトリーズ 長期放出性ヒドロコドンアセトアミノフェンならびにその関連方法および用途
KR101753222B1 (ko) 2014-12-12 2017-07-04 강원대학교산학협력단 용융압출하여 제조된 당귀-고체분산체 및 그 제조방법
WO2018111459A1 (en) * 2016-12-14 2018-06-21 Dow Global Technologies Llc Method for generating salts of pharmaceutical active ingredients
AU2019275409B2 (en) 2018-05-24 2024-08-15 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
AU2019275406A1 (en) 2018-05-24 2020-07-16 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH668553A5 (de) * 1987-02-02 1989-01-13 Mepha Ag Arzneimittel mit verzoegerter wirkstofffreisetzung.
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
WO1993007859A1 (en) * 1991-10-23 1993-04-29 Warner-Lambert Company Novel pharmaceutical pellets and process for their production
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
US5695781A (en) * 1995-03-01 1997-12-09 Hallmark Pharmaceuticals, Inc. Sustained release formulation containing three different types of polymers
WO1997045091A2 (en) 1996-05-31 1997-12-04 Euro-Celtique, S.A. Sustained release oxycodone formulations with no fed/fast effect
US6673367B1 (en) 1998-12-17 2004-01-06 Euro-Celtique, S.A. Controlled/modified release oral methylphenidate formulations
DE19958007A1 (de) 1999-12-02 2001-06-07 Roehm Gmbh Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen
EP1368007B1 (de) 2001-02-27 2005-10-05 Röhm GmbH & Co. KG Überzugs- und bindemittel für arzneimittelformulierungen mit verbesserter lagerstabilität
DE10239999A1 (de) 2002-08-27 2004-03-04 Röhm GmbH & Co. KG Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen

Also Published As

Publication number Publication date
PL370426A1 (en) 2005-05-30
BRPI0307995B8 (pt) 2021-05-25
JP5054278B2 (ja) 2012-10-24
WO2003072083A3 (de) 2004-04-08
US20040253314A1 (en) 2004-12-16
MXPA04008345A (es) 2004-11-26
CA2474691C (en) 2011-04-19
EP1478344B1 (de) 2007-05-23
US8642089B2 (en) 2014-02-04
DE10208344A1 (de) 2003-09-04
DE50307321D1 (de) 2007-07-05
JP2005526731A (ja) 2005-09-08
IL162082A (en) 2009-11-18
AU2003210196A1 (en) 2003-09-09
ES2286447T3 (es) 2007-12-01
PL204465B1 (pl) 2010-01-29
ATE362754T1 (de) 2007-06-15
EP1478344A2 (de) 2004-11-24
BRPI0307995B1 (pt) 2019-02-26
CA2474691A1 (en) 2003-09-04
KR20040084936A (ko) 2004-10-06
KR100707712B1 (ko) 2007-04-16
BR0307995A (pt) 2004-12-07
WO2003072083A2 (de) 2003-09-04

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