IL155178A0 - Use of chemokine mutants in multiple sclerosis, some such new mutants and their preparation - Google Patents

Use of chemokine mutants in multiple sclerosis, some such new mutants and their preparation

Info

Publication number
IL155178A0
IL155178A0 IL15517801A IL15517801A IL155178A0 IL 155178 A0 IL155178 A0 IL 155178A0 IL 15517801 A IL15517801 A IL 15517801A IL 15517801 A IL15517801 A IL 15517801A IL 155178 A0 IL155178 A0 IL 155178A0
Authority
IL
Israel
Prior art keywords
mutants
preparation
multiple sclerosis
chemokine
new
Prior art date
Application number
IL15517801A
Other languages
English (en)
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of IL155178A0 publication Critical patent/IL155178A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15517801A 2000-10-04 2001-10-03 Use of chemokine mutants in multiple sclerosis, some such new mutants and their preparation IL155178A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00121665 2000-10-04
PCT/EP2001/011428 WO2002028419A2 (en) 2000-10-04 2001-10-03 Chemokine mutants in the treatment of multiple sclerosis

Publications (1)

Publication Number Publication Date
IL155178A0 true IL155178A0 (en) 2003-11-23

Family

ID=8170011

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15517801A IL155178A0 (en) 2000-10-04 2001-10-03 Use of chemokine mutants in multiple sclerosis, some such new mutants and their preparation
IL155178A IL155178A (en) 2000-10-04 2003-04-01 Use of Kamokin mutants to prepare a drug for the treatment of multiple sclerosis, such new mutants and their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL155178A IL155178A (en) 2000-10-04 2003-04-01 Use of Kamokin mutants to prepare a drug for the treatment of multiple sclerosis, such new mutants and their preparation

Country Status (30)

Country Link
US (1) US7402303B2 (pl)
EP (1) EP1326628B1 (pl)
JP (1) JP3908165B2 (pl)
KR (1) KR100837898B1 (pl)
CN (1) CN1285381C (pl)
AR (1) AR030854A1 (pl)
AT (1) ATE265222T1 (pl)
AU (2) AU1591902A (pl)
BG (1) BG66137B1 (pl)
BR (1) BR0114407A (pl)
CA (1) CA2423616C (pl)
CZ (1) CZ303409B6 (pl)
DE (1) DE60103078T2 (pl)
DK (1) DK1326628T3 (pl)
EA (1) EA006137B1 (pl)
EE (1) EE05174B1 (pl)
ES (1) ES2217199T3 (pl)
HR (1) HRP20030215B1 (pl)
HU (1) HUP0302194A3 (pl)
IL (2) IL155178A0 (pl)
MX (1) MXPA03003008A (pl)
NO (1) NO330278B1 (pl)
PL (1) PL204231B1 (pl)
PT (1) PT1326628E (pl)
RS (1) RS50738B (pl)
SI (1) SI1326628T1 (pl)
SK (1) SK287523B6 (pl)
UA (1) UA77950C2 (pl)
WO (1) WO2002028419A2 (pl)
ZA (1) ZA200302315B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1458756B1 (en) 2001-12-17 2009-01-28 Laboratoires Serono SA Chemokine mutants acting as chemokine antagonists
DE60303929T2 (de) 2002-04-04 2006-08-10 Applied Research Systems Ars Holding N.V. Chemokin-muntanten mit verbesserter oraler bioverfügbarkeit
ES2305573T3 (es) * 2002-12-23 2008-11-01 Laboratoires Serono Sa Uso de metantes de quimiocinas cc ccl5/rantes contra transtornos del higado.
EP1673388B1 (en) * 2003-10-22 2008-11-26 Laboratoires Serono SA Cxcl8 antagonists
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
DK1439191T3 (da) * 2004-01-19 2006-08-14 Ares Trading Sa Proces til oprensning af bakterielt udtrykte proteiner
GB0412400D0 (en) * 2004-06-03 2004-07-07 Univ Newcastle Treatment of inflammatory conditions
EP1760110B1 (en) * 2005-09-03 2011-11-02 Samsung SDI Co., Ltd. Polybenzoxazine-based compound, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane
GB0614755D0 (en) 2006-07-25 2006-09-06 Univ Geneve Cytokine derivatives
EP2185719B1 (en) 2007-08-02 2013-11-13 NovImmune SA Anti-rantes antibodies and methods of use thereof
CN102781952B (zh) * 2010-02-08 2015-09-02 宾夕法尼亚大学托管会 编码rantes的核酸分子、包含其的组合物以及其使用方法
CN112469430B (zh) 2018-05-28 2024-12-24 日内瓦大学 抑制大脑炎症的方法
US20250186520A1 (en) * 2020-10-26 2025-06-12 City Of Hope Oncolytic virus compositions and methods for the treatment of cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739103A (en) * 1993-11-12 1998-04-14 Dana-Farber Cancer Institute Chemokine N-terminal deletion mutations
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists
EP0906954A1 (en) * 1997-09-29 1999-04-07 Applied Research Systems ARS Holding N.V. Amino-terminal truncated c-c chemokines as chemokine antagonist
EP1040191B1 (en) * 1997-12-23 2005-11-02 Fondazione Centro San Raffaele Del Monte Tabor Rantes mutants and therapeutic applications thereof
JP2002535376A (ja) * 1999-01-29 2002-10-22 ミレニアム・ファーマシューティカルズ・インコーポレイテッド Ｃｃｒ１アンタゴニストを用いた脱髄性炎症性疾患の治療方法

Also Published As

Publication number Publication date
NO20031525L (no) 2003-04-03
PL362350A1 (pl) 2004-10-18
DE60103078T2 (de) 2005-04-07
KR100837898B1 (ko) 2008-06-13
KR20030034238A (ko) 2003-05-01
NO20031525D0 (no) 2003-04-03
WO2002028419A3 (en) 2002-06-13
CZ303409B6 (cs) 2012-09-05
DK1326628T3 (da) 2004-08-09
HUP0302194A2 (hu) 2003-10-28
AR030854A1 (es) 2003-09-03
EP1326628B1 (en) 2004-04-28
HUP0302194A3 (en) 2005-12-28
JP2004510426A (ja) 2004-04-08
CN1477969A (zh) 2004-02-25
YU25703A (sh) 2006-05-25
ES2217199T3 (es) 2004-11-01
CA2423616A1 (en) 2002-04-11
SK4062003A3 (en) 2003-08-05
NO330278B1 (no) 2011-03-21
UA77950C2 (en) 2007-02-15
CA2423616C (en) 2010-03-16
US7402303B2 (en) 2008-07-22
AU2002215919B2 (en) 2005-11-24
BR0114407A (pt) 2003-07-29
RS50738B (sr) 2010-08-31
CN1285381C (zh) 2006-11-22
WO2002028419A2 (en) 2002-04-11
US20040101509A1 (en) 2004-05-27
SI1326628T1 (en) 2004-10-31
BG66137B1 (bg) 2011-07-29
EA200300439A1 (ru) 2003-08-28
JP3908165B2 (ja) 2007-04-25
PL204231B1 (pl) 2009-12-31
HK1062811A1 (en) 2004-11-26
SK287523B6 (sk) 2011-01-04
HRP20030215B1 (en) 2011-09-30
DE60103078D1 (de) 2004-06-03
EA006137B1 (ru) 2005-10-27
IL155178A (en) 2009-07-20
EE200300139A (et) 2003-06-16
EP1326628A2 (en) 2003-07-16
ZA200302315B (en) 2004-03-25
HRP20030215A2 (en) 2005-02-28
ATE265222T1 (de) 2004-05-15
EE05174B1 (et) 2009-06-15
BG107685A (bg) 2003-11-28
CZ2003947A3 (cs) 2003-11-12
AU1591902A (en) 2002-04-15
PT1326628E (pt) 2004-09-30
MXPA03003008A (es) 2003-07-14

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