IL155066A - History 2 - Amino - 2 - (2 - Ethyl (converted)) Propane - 1, 3 - Diol Efficacy in the preparation of 2 - Aminopropene - 1, 3 - Diol - Google Patents

History 2 - Amino - 2 - (2 - Ethyl (converted)) Propane - 1, 3 - Diol Efficacy in the preparation of 2 - Aminopropene - 1, 3 - Diol

Info

Publication number
IL155066A
IL155066A IL15506698A IL15506698A IL155066A IL 155066 A IL155066 A IL 155066A IL 15506698 A IL15506698 A IL 15506698A IL 15506698 A IL15506698 A IL 15506698A IL 155066 A IL155066 A IL 155066A
Authority
IL
Israel
Prior art keywords
compound
acid
reaction
present
ethyl
Prior art date
Application number
IL15506698A
Other languages
English (en)
Hebrew (he)
Other versions
IL155066A0 (en
Original Assignee
Mitsubishi Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp
Publication of IL155066A0 publication Critical patent/IL155066A0/xx
Publication of IL155066A publication Critical patent/IL155066A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/16—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same carbon atom of an acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
IL15506698A 1997-04-04 1998-04-03 History 2 - Amino - 2 - (2 - Ethyl (converted)) Propane - 1, 3 - Diol Efficacy in the preparation of 2 - Aminopropene - 1, 3 - Diol IL155066A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8625597 1997-04-04
PCT/JP1998/001571 WO1998045249A1 (fr) 1997-04-04 1998-04-03 Composes 2-aminopropane-1,3-diol, leur utilisation pharmaceutique, et intermediaires servant a leur synthese
IL13220898A IL132208A (en) 1997-04-04 1998-04-03 2-aminopropane-1,3-diol derivatives and pharmaceutical compositions containing the same

Publications (2)

Publication Number Publication Date
IL155066A0 IL155066A0 (en) 2003-10-31
IL155066A true IL155066A (en) 2004-06-20

Family

ID=13881722

Family Applications (3)

Application Number Title Priority Date Filing Date
IL13220898A IL132208A (en) 1997-04-04 1998-04-03 2-aminopropane-1,3-diol derivatives and pharmaceutical compositions containing the same
IL15506598A IL155065A (en) 1997-04-04 1998-04-03 History - 2 Aminopropene - 1, 3 - Diol and Pharmaceutical Preparations Containing Them
IL15506698A IL155066A (en) 1997-04-04 1998-04-03 History 2 - Amino - 2 - (2 - Ethyl (converted)) Propane - 1, 3 - Diol Efficacy in the preparation of 2 - Aminopropene - 1, 3 - Diol

Family Applications Before (2)

Application Number Title Priority Date Filing Date
IL13220898A IL132208A (en) 1997-04-04 1998-04-03 2-aminopropane-1,3-diol derivatives and pharmaceutical compositions containing the same
IL15506598A IL155065A (en) 1997-04-04 1998-04-03 History - 2 Aminopropene - 1, 3 - Diol and Pharmaceutical Preparations Containing Them

Country Status (18)

Country Link
US (2) USRE39072E1 (zh)
EP (2) EP1319651B1 (zh)
JP (1) JP4045364B2 (zh)
KR (1) KR100551931B1 (zh)
CN (2) CN1290819C (zh)
AT (2) ATE271028T1 (zh)
AU (1) AU735853B2 (zh)
BR (1) BR9808481A (zh)
CA (1) CA2286315C (zh)
DE (2) DE69830756T2 (zh)
DK (2) DK1319651T3 (zh)
ES (2) ES2226110T3 (zh)
IL (3) IL132208A (zh)
NZ (1) NZ500713A (zh)
PT (2) PT1002792E (zh)
RU (1) RU2198162C2 (zh)
SI (2) SI1319651T1 (zh)
WO (1) WO1998045249A1 (zh)

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WO2003029184A1 (fr) * 2001-09-27 2003-04-10 Kyorin Pharmaceutical Co., Ltd. Derive d'ether de diaryle, son sel d'addition et son immunosuppresseur
AU2002332289B2 (en) * 2001-09-27 2007-05-10 Kyorin Pharmaceutical Co., Ltd. Diaryl sulfide derivative, addition salt thereof, and immunosuppressant
GB0125443D0 (en) * 2001-10-23 2001-12-12 Novartis Ag Organic Compounds
EP1471054B1 (en) * 2002-01-11 2009-07-01 Daiichi Sankyo Company, Limited Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
US6797722B2 (en) * 2002-05-03 2004-09-28 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases
NZ536513A (en) 2002-05-16 2007-10-26 Novartis Ag Use of EDG receptor binding agents in cancer
GB0217152D0 (en) 2002-07-24 2002-09-04 Novartis Ag Organic compounds
AU2003273865A1 (en) 2002-09-13 2004-04-30 Novartis Ag Amino-propanol derivatives
BR0314760A (pt) * 2002-09-24 2005-07-26 Novartis Ag Compostos orgânicos
AU2011205050B2 (en) * 2003-04-08 2014-01-30 Mitsubishi Tanabe Pharma Corporation Solid pharmaceutical compositions comprising a S1P receptor agonist and a sugar alcohol
AU2008200368B2 (en) * 2003-04-08 2011-04-28 Mitsubishi Tanabe Pharma Corporation Solid pharmaceutical compositions comprising a S1P receptor agonist and a sugar alcohol
NZ586280A (en) * 2003-04-08 2011-12-22 Novartis Ag Oral pharmaceutical composition comprising FTY720 and mannitol
CN1777575B (zh) * 2003-04-30 2010-05-12 诺瓦提斯公司 作为1-磷酸-鞘氨醇受体调节剂的氨基-丙醇衍生物
MY150088A (en) 2003-05-19 2013-11-29 Irm Llc Immunosuppressant compounds and compositions
US7524887B2 (en) 2003-06-06 2009-04-28 Sanofi-Aventis Deutschland Gmbh 2-amino-1,3-propanediol compounds for the treatment of acute pain
EP1484057A1 (en) * 2003-06-06 2004-12-08 Aventis Pharma Deutschland GmbH Use of 2-amino-1-3-propanediol derivatives for the manufacture of a medicament for the treatment of various types of pain
US20040265238A1 (en) 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
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DK1772145T3 (da) 2004-07-16 2011-05-30 Kyorin Seiyaku Kk Fremgangsmåde til effektiv anvendelse af medicin og fremgangsmåde til forebyggelse af bivirkninger
JP4919374B2 (ja) * 2004-07-29 2012-04-18 第一三共株式会社 免疫抑制剤としての医薬組成物
TW200611687A (en) * 2004-07-29 2006-04-16 Sankyo Co Pharmaceutical compositions used for immunosuppressant
CA2574664C (en) 2004-07-30 2013-01-15 Novartis Ag Compound formulations of 2-amino-1,3-propanediol compounds
RU2007109207A (ru) * 2004-08-13 2008-09-20 Прикис Фамэсьютикэлс, Инк. (US) Соединения-модуляторы активности рецептора сфингозин-1-фосфата (варианты), фармацевтическая композиция, содержащая указанные соединения, и способ лечения нарушения, ассоциированного со сфингозин-1-фосфатом
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Also Published As

Publication number Publication date
AU735853B2 (en) 2001-07-19
EP1319651A2 (en) 2003-06-18
CN1137086C (zh) 2004-02-04
SI1002792T1 (en) 2004-12-31
DE69825056T2 (de) 2005-08-25
KR100551931B1 (ko) 2006-02-16
US6214873B1 (en) 2001-04-10
BR9808481A (pt) 2000-05-23
AU6523098A (en) 1998-10-30
CN1480450A (zh) 2004-03-10
CA2286315C (en) 2007-03-06
ES2226110T3 (es) 2005-03-16
EP1002792A1 (en) 2000-05-24
CN1290819C (zh) 2006-12-20
NZ500713A (en) 2000-07-28
ATE271028T1 (de) 2004-07-15
WO1998045249A1 (fr) 1998-10-15
USRE39072E1 (en) 2006-04-18
SI1319651T1 (en) 2005-10-31
RU2198162C2 (ru) 2003-02-10
DK1002792T3 (da) 2004-11-22
EP1002792B1 (en) 2004-07-14
DE69830756D1 (de) 2005-08-04
DE69830756T2 (de) 2006-05-04
EP1319651A3 (en) 2004-01-02
EP1002792A4 (en) 2002-03-20
IL155065A (en) 2004-01-04
DE69825056D1 (de) 2004-08-19
KR20010006004A (ko) 2001-01-15
CA2286315A1 (en) 1998-10-15
IL155066A0 (en) 2003-10-31
IL155065A0 (en) 2003-10-31
EP1319651B1 (en) 2005-06-29
CN1259117A (zh) 2000-07-05
PT1319651E (pt) 2005-09-30
ES2240868T3 (es) 2005-10-16
JP4045364B2 (ja) 2008-02-13
PT1002792E (pt) 2004-12-31
IL132208A0 (en) 2001-03-19
IL132208A (en) 2003-07-31
DK1319651T3 (da) 2005-08-01
ATE298740T1 (de) 2005-07-15

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