IL155065A - History - 2 Aminopropene - 1, 3 - Diol and Pharmaceutical Preparations Containing Them - Google Patents

History - 2 Aminopropene - 1, 3 - Diol and Pharmaceutical Preparations Containing Them

Info

Publication number
IL155065A
IL155065A IL15506598A IL15506598A IL155065A IL 155065 A IL155065 A IL 155065A IL 15506598 A IL15506598 A IL 15506598A IL 15506598 A IL15506598 A IL 15506598A IL 155065 A IL155065 A IL 155065A
Authority
IL
Israel
Prior art keywords
compound
acid
reaction
present
hydrate
Prior art date
Application number
IL15506598A
Other languages
English (en)
Hebrew (he)
Other versions
IL155065A0 (en
Original Assignee
Mitsubishi Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp
Publication of IL155065A0 publication Critical patent/IL155065A0/xx
Publication of IL155065A publication Critical patent/IL155065A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/16—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same carbon atom of an acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL15506598A 1997-04-04 1998-04-03 History - 2 Aminopropene - 1, 3 - Diol and Pharmaceutical Preparations Containing Them IL155065A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8625597 1997-04-04
IL13220898A IL132208A (en) 1997-04-04 1998-04-03 2-aminopropane-1,3-diol derivatives and pharmaceutical compositions containing the same
PCT/JP1998/001571 WO1998045249A1 (fr) 1997-04-04 1998-04-03 Composes 2-aminopropane-1,3-diol, leur utilisation pharmaceutique, et intermediaires servant a leur synthese

Publications (2)

Publication Number Publication Date
IL155065A0 IL155065A0 (en) 2003-10-31
IL155065A true IL155065A (en) 2004-01-04

Family

ID=13881722

Family Applications (3)

Application Number Title Priority Date Filing Date
IL15506598A IL155065A (en) 1997-04-04 1998-04-03 History - 2 Aminopropene - 1, 3 - Diol and Pharmaceutical Preparations Containing Them
IL15506698A IL155066A (en) 1997-04-04 1998-04-03 History 2 - Amino - 2 - (2 - Ethyl (converted)) Propane - 1, 3 - Diol Efficacy in the preparation of 2 - Aminopropene - 1, 3 - Diol
IL13220898A IL132208A (en) 1997-04-04 1998-04-03 2-aminopropane-1,3-diol derivatives and pharmaceutical compositions containing the same

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL15506698A IL155066A (en) 1997-04-04 1998-04-03 History 2 - Amino - 2 - (2 - Ethyl (converted)) Propane - 1, 3 - Diol Efficacy in the preparation of 2 - Aminopropene - 1, 3 - Diol
IL13220898A IL132208A (en) 1997-04-04 1998-04-03 2-aminopropane-1,3-diol derivatives and pharmaceutical compositions containing the same

Country Status (18)

Country Link
US (2) US6214873B1 (fr)
EP (2) EP1002792B1 (fr)
JP (1) JP4045364B2 (fr)
KR (1) KR100551931B1 (fr)
CN (2) CN1137086C (fr)
AT (2) ATE298740T1 (fr)
AU (1) AU735853B2 (fr)
BR (1) BR9808481A (fr)
CA (1) CA2286315C (fr)
DE (2) DE69830756T2 (fr)
DK (2) DK1319651T3 (fr)
ES (2) ES2240868T3 (fr)
IL (3) IL155065A (fr)
NZ (1) NZ500713A (fr)
PT (2) PT1319651E (fr)
RU (1) RU2198162C2 (fr)
SI (2) SI1319651T1 (fr)
WO (1) WO1998045249A1 (fr)

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WO2002064616A2 (fr) 2001-01-30 2002-08-22 University Of Virgina Patent Foundation Agonistes et antagonistes de recepteurs de sphingosine-1-phosphate
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US20030072717A1 (en) * 2001-02-23 2003-04-17 Vapotronics, Inc. Inhalation device having an optimized air flow path
DE60208355T2 (de) * 2001-03-26 2006-07-27 Novartis Ag 2-amino-propanol derivate
EP1389137B1 (fr) * 2001-05-21 2006-07-19 InJet Digital Aerosols Limited Compositions pour l'administration de proteines par la voie pulmonaire
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JP4152884B2 (ja) 2001-09-27 2008-09-17 杏林製薬株式会社 ジアリールエーテル誘導体とその付加塩及び免疫抑制剤
CN1329372C (zh) * 2001-09-27 2007-08-01 杏林制药株式会社 二芳基硫醚衍生物及其加成盐和免疫抑制剂
GB0125443D0 (en) * 2001-10-23 2001-12-12 Novartis Ag Organic Compounds
AU2003202495B2 (en) * 2002-01-11 2006-07-20 Sankyo Company, Limited Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
US6797722B2 (en) * 2002-05-03 2004-09-28 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases
DE60324416D1 (de) 2002-05-16 2008-12-11 Novartis Ag Verwendung von edg rezeptor bindenden wirkstoffen für die krebstherapie
GB0217152D0 (en) * 2002-07-24 2002-09-04 Novartis Ag Organic compounds
AU2003273865A1 (en) * 2002-09-13 2004-04-30 Novartis Ag Amino-propanol derivatives
RU2478378C2 (ru) 2002-09-24 2013-04-10 Новартис Аг Органические соединения
PE20150676A1 (es) * 2003-04-08 2015-05-17 Novartis Ag Composicion farmaceutica que contiene un agonista del receptor s1p y un alcohol de azucar
AU2008200368B2 (en) * 2003-04-08 2011-04-28 Mitsubishi Tanabe Pharma Corporation Solid pharmaceutical compositions comprising a S1P receptor agonist and a sugar alcohol
AU2011205050B2 (en) * 2003-04-08 2014-01-30 Mitsubishi Tanabe Pharma Corporation Solid pharmaceutical compositions comprising a S1P receptor agonist and a sugar alcohol
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MY150088A (en) 2003-05-19 2013-11-29 Irm Llc Immunosuppressant compounds and compositions
EP1484057A1 (fr) * 2003-06-06 2004-12-08 Aventis Pharma Deutschland GmbH Utilization des derives de 2-amino-1,3-propanediol pour la preparation d'un medicament destine au traitement des certains douleurs
US7524887B2 (en) 2003-06-06 2009-04-28 Sanofi-Aventis Deutschland Gmbh 2-amino-1,3-propanediol compounds for the treatment of acute pain
US20040265238A1 (en) * 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
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EP1750722A4 (fr) 2004-05-06 2010-03-10 Univ Virginia Nouveaux antagonistes selectifs du recepteur de l'acide lysophosphatidique
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US20110104186A1 (en) 2004-06-24 2011-05-05 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
EP1772145B1 (fr) * 2004-07-16 2011-03-23 Kyorin Pharmaceutical Co., Ltd. Procédé d'utilisation efficace d'un médicament et procédé concernant la prévention d'effets secondaires
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JP4919374B2 (ja) * 2004-07-29 2012-04-18 第一三共株式会社 免疫抑制剤としての医薬組成物
US20080096972A1 (en) 2004-07-30 2008-04-24 Thitiwan Buranachokpaisan Compound formulations of 2-amino-1, 3-propanediol compounds
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KR20070085465A (ko) 2004-11-29 2007-08-27 노파르티스 아게 Ｓ１ｐ 수용체 효능제의 투여 용법
CA2595960A1 (fr) * 2005-02-08 2006-08-17 Novartis Ag Induction d'un anticorps antilymphocyte
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EP2007789B1 (fr) 2006-04-11 2015-05-20 Novartis AG Inhibiteurs spirocycliques du VIH/du virus de l'hépatite C
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KR102044064B1 (ko) 2006-09-26 2019-11-12 노파르티스 아게 Ｓ１ｐ 조정제를 포함하는 제약 조성물
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JP5341754B2 (ja) 2007-06-14 2013-11-13 田辺三菱製薬株式会社 アミン化合物及びその医薬用途
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KR101600098B1 (ko) 2007-10-12 2016-03-04 노파르티스 아게 스핑고신 1 포스페이트 (ｓ1ｐ) 수용체 조절제를 포함하는 조성물
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US8512690B2 (en) 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors
US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
US9011833B2 (en) 2010-10-08 2015-04-21 Novartis Ag Vitamin E formulations of sulfamide NS3 inhibitors
JO3177B1 (ar) 2011-04-01 2018-03-08 Novartis Ag تركيبات تتالف من 2-أمينو-2- [ 2- ( 4- أكتيل فينيل ) إثيل ] بروبان - 3, 1- ديول
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CN110862409B (zh) * 2019-12-04 2021-08-20 江南大学 一种制备含二元醇结构的硅烷类化合物及其改性水性聚氨酯的方法
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US3660488A (en) 1965-07-16 1972-05-02 Phillips Petroleum Co 2-halo-alkylene- and -cyclopentylene-2-amino-propane 1 3-diols
DE122011100012I1 (de) * 1992-10-21 2011-10-20 Mitsubishi Tanabe Pharma Corp 2-Amino-1, 3-propandiolverbindung und immunosuppressium.
DE69524962T4 (de) 1994-08-22 2003-08-28 Mitsubishi Pharma Corp., Osaka Benzolderivate und deren medizinische verwendung

Also Published As

Publication number Publication date
DE69825056D1 (de) 2004-08-19
CN1480450A (zh) 2004-03-10
DK1002792T3 (da) 2004-11-22
KR100551931B1 (ko) 2006-02-16
CA2286315A1 (fr) 1998-10-15
KR20010006004A (ko) 2001-01-15
DK1319651T3 (da) 2005-08-01
PT1002792E (pt) 2004-12-31
EP1319651A2 (fr) 2003-06-18
SI1319651T1 (en) 2005-10-31
EP1002792A1 (fr) 2000-05-24
CN1290819C (zh) 2006-12-20
BR9808481A (pt) 2000-05-23
IL132208A0 (en) 2001-03-19
IL155066A0 (en) 2003-10-31
ES2240868T3 (es) 2005-10-16
USRE39072E1 (en) 2006-04-18
EP1002792A4 (fr) 2002-03-20
EP1319651B1 (fr) 2005-06-29
ES2226110T3 (es) 2005-03-16
DE69830756D1 (de) 2005-08-04
ATE298740T1 (de) 2005-07-15
IL132208A (en) 2003-07-31
JP4045364B2 (ja) 2008-02-13
ATE271028T1 (de) 2004-07-15
NZ500713A (en) 2000-07-28
PT1319651E (pt) 2005-09-30
EP1002792B1 (fr) 2004-07-14
DE69830756T2 (de) 2006-05-04
AU6523098A (en) 1998-10-30
CN1259117A (zh) 2000-07-05
CA2286315C (fr) 2007-03-06
US6214873B1 (en) 2001-04-10
IL155066A (en) 2004-06-20
IL155065A0 (en) 2003-10-31
WO1998045249A1 (fr) 1998-10-15
EP1319651A3 (fr) 2004-01-02
CN1137086C (zh) 2004-02-04
RU2198162C2 (ru) 2003-02-10
AU735853B2 (en) 2001-07-19
DE69825056T2 (de) 2005-08-25
SI1002792T1 (en) 2004-12-31

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