IL153705A0 - Method of making particles for use in a pharmaceutical composition - Google Patents
Method of making particles for use in a pharmaceutical compositionInfo
- Publication number
- IL153705A0 IL153705A0 IL15370501A IL15370501A IL153705A0 IL 153705 A0 IL153705 A0 IL 153705A0 IL 15370501 A IL15370501 A IL 15370501A IL 15370501 A IL15370501 A IL 15370501A IL 153705 A0 IL153705 A0 IL 153705A0
- Authority
- IL
- Israel
- Prior art keywords
- particles
- pharmaceutical composition
- making particles
- excipient
- milling
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00113608 | 2000-06-27 | ||
GB0029263A GB0029263D0 (en) | 2000-11-30 | 2000-11-30 | Method of making particles for use in a pharmaceutical composition |
PCT/GB2001/001732 WO2001078694A2 (en) | 2000-04-17 | 2001-04-17 | Formulations for use in inhaler devices |
PCT/GB2001/002860 WO2002000197A1 (en) | 2000-06-27 | 2001-06-27 | Method of making particles for use in a pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
IL153705A0 true IL153705A0 (en) | 2003-07-06 |
Family
ID=26071085
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15370501A IL153705A0 (en) | 2000-06-27 | 2001-06-27 | Method of making particles for use in a pharmaceutical composition |
IL153705A IL153705A (en) | 2000-06-27 | 2002-12-26 | A method of creating particles for use in a pharmaceutical preparation |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL153705A IL153705A (en) | 2000-06-27 | 2002-12-26 | A method of creating particles for use in a pharmaceutical preparation |
Country Status (11)
Country | Link |
---|---|
US (4) | US7744855B2 (es) |
EP (3) | EP1296651B2 (es) |
KR (1) | KR100949539B1 (es) |
CN (1) | CN100551358C (es) |
AT (1) | ATE378039T1 (es) |
DK (1) | DK1913939T3 (es) |
ES (2) | ES2292598T3 (es) |
HK (1) | HK1056115A1 (es) |
IL (2) | IL153705A0 (es) |
PT (2) | PT1296651E (es) |
WO (1) | WO2002000197A1 (es) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9501841D0 (en) * | 1995-01-31 | 1995-03-22 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
GB9515182D0 (en) * | 1995-07-24 | 1995-09-20 | Co Ordinated Drug Dev | Improvements in and relating to powders for use in dry powder inhalers |
PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
GB0009468D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formulations for use in inhaler devices |
GB0009469D0 (en) | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
EP1296651B2 (en) | 2000-06-27 | 2019-07-17 | Vectura Limited | Method of making particles for use in a pharmaceutical composition |
EP2298285A3 (en) | 2000-11-30 | 2011-07-27 | Vectura Limited | Method of making particles for use in a pharmaceutical composition |
AU2002220857A1 (en) | 2000-11-30 | 2002-06-11 | Vectura Limited | Particles for use in a pharmaceutical composition |
GB0208742D0 (en) * | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
US8337816B2 (en) | 2001-09-17 | 2012-12-25 | Glaxo Group Limited | Dry powder medicament formulations |
US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
CN102688224A (zh) * | 2003-04-14 | 2012-09-26 | 维克特拉有限公司 | 用于提高剂量效率的药物组合物和装置 |
US7094545B2 (en) | 2003-04-30 | 2006-08-22 | Ferring Bv | Pharmaceutical composition as solid dosage form and method for manufacturing thereof |
WO2005000267A2 (en) * | 2003-05-28 | 2005-01-06 | Nektar Therapeutics | Spray drying of an alcoholic aqueous solution for the manufacture of a water-insoluble active agentmicroparticle with a partial or complete amino acid and/or phospholipid coat |
JP2009513529A (ja) * | 2003-07-11 | 2009-04-02 | グラクソ グループ リミテッド | ステアリン酸マグネシウムを含む医薬製剤 |
DE60301351T2 (de) | 2003-07-25 | 2006-01-19 | Ferring B.V. | Pharmazeutische Desmopressin-Zubereitung als feste Darreichungsform und Methode zu ihrer Herstellung |
GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
WO2005025550A1 (en) * | 2003-09-15 | 2005-03-24 | Vectura Limited | Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation |
GB0321607D0 (en) | 2003-09-15 | 2003-10-15 | Vectura Ltd | Manufacture of pharmaceutical compositions |
GB0324918D0 (en) * | 2003-10-24 | 2003-11-26 | Glaxo Group Ltd | Composition |
US7018653B2 (en) | 2003-12-29 | 2006-03-28 | Ferring B.V. | Method for preparing solid dosage form of desmopressin |
DE102004011512B4 (de) * | 2004-03-08 | 2022-01-13 | Boehringer Ingelheim Vetmedica Gmbh | Pharmazeutische Zubereitung enthaltend Pimobendan |
EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
GB0409703D0 (en) | 2004-04-30 | 2004-06-02 | Vectura Ltd | Pharmaceutical compositions |
GB0425758D0 (en) * | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
GB0426301D0 (en) * | 2004-11-30 | 2004-12-29 | Vectura Ltd | Pharmaceutical formulations |
CN104177448A (zh) | 2005-02-10 | 2014-12-03 | 葛兰素集团有限公司 | 使用预分选技术制备乳糖的方法以及由此形成的药物制剂 |
ITMI20051999A1 (it) | 2005-10-21 | 2007-04-22 | Eratech S R L | Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita' |
GB0613161D0 (en) | 2006-06-30 | 2006-08-09 | Novartis Ag | Organic Compounds |
IN2014MN00380A (es) | 2006-06-30 | 2015-06-19 | Iceutica Pty Ltd | |
EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
JP2010537989A (ja) * | 2007-09-03 | 2010-12-09 | ナノセラピューティクス・インコーポレイテッド | 難溶性薬物の組成物及び送達方法 |
EP2080508A1 (en) | 2008-01-15 | 2009-07-22 | CHIESI FARMACEUTICI S.p.A. | Dry powder formulation comprising an anticholinergic drug |
WO2009142852A2 (en) | 2008-05-22 | 2009-11-26 | 3M Innovative Properties Company | Process for manufacturing flowable powder drug compositions |
EP2309978B1 (en) | 2008-06-26 | 2018-12-26 | 3M Innovative Properties Company | Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof |
WO2010002613A2 (en) | 2008-07-02 | 2010-01-07 | 3M Innovative Properties Company | Method of making a dry powder pharmaceutical composition |
PL2370070T3 (pl) | 2008-11-25 | 2014-02-28 | Boehringer Ingelheim Vetmedica Gmbh | Pimobendan do zastosowania w leczeniu kardiomiopatii przerostowej u kotów |
KR101639098B1 (ko) | 2009-03-26 | 2016-07-12 | 풀매트릭스 오퍼레이팅 컴퍼니, 인크 | 폐 질환 치료용 건조 분말 제형 및 방법 |
WO2010121328A1 (en) | 2009-04-24 | 2010-10-28 | Iceutica Pty Ltd | A novel formulation of indomethacin |
MX2011011123A (es) * | 2009-04-24 | 2011-11-04 | Schering Corp | Formulaciones de aglomerado utiles en inhaladores de polvo seco. |
EP2421510B1 (en) * | 2009-04-24 | 2019-07-31 | Iceutica Pty Ltd. | Production of encapsulated nanoparticles at commercial scale |
GB0921481D0 (en) | 2009-12-08 | 2010-01-20 | Vectura Ltd | Process and product |
SG181673A1 (en) * | 2009-12-14 | 2012-07-30 | Chiesi Farma Spa | Antibiotic microparticles for inhalation |
US9228785B2 (en) | 2010-05-04 | 2016-01-05 | Alexander Poltorak | Fractal heat transfer device |
UA107499C2 (uk) | 2010-06-22 | 2015-01-12 | Chiesi Farm Spa | Склад сухого порошку, який містить антимускариновий засіб |
MX346424B (es) | 2010-08-03 | 2017-03-21 | Chiesi Farm Spa | Formulacion de polvo seco que comprende un inhibidor de fosfodiesterasa. |
EP2448571B1 (en) | 2010-08-30 | 2013-06-12 | Pulmatrix, Inc. | Respirably dry powder comprising calcium lactate, sodium chloride and leucine |
CN105640925B (zh) | 2010-08-30 | 2019-08-16 | 普马特里克斯营业公司 | 干燥粉末配方及用于治疗肺部疾病的方法 |
MX354828B (es) | 2010-09-29 | 2018-03-22 | Pulmatrix Operating Co Inc | Polvos secos de cationes metálicos monovalentes para inhalación. |
DK3470057T3 (da) | 2010-09-29 | 2021-11-22 | Pulmatrix Operating Co Inc | Kationiske tørpulvere omfattende magnesiumsalt |
TW201304822A (zh) | 2010-11-15 | 2013-02-01 | Vectura Ltd | 組成物及用途 |
WO2012073025A1 (en) | 2010-11-30 | 2012-06-07 | Vectura Limited | Glucosaminoglucans such as heparin for use in the treatment of pulmonary inflammation such as copd |
AU2013225982B2 (en) | 2012-02-29 | 2017-11-30 | Pulmatrix, Inc. | Inhalable dry powders |
HUE060093T2 (hu) | 2012-03-15 | 2023-01-28 | Boehringer Ingelheim Vetmedica Gmbh | Gyógyszerészeti tablettakészítmény az állatgyógyászati ágazat számára, eljárás annak elõállítására és annak alkalmazása |
JP6473738B2 (ja) | 2013-04-01 | 2019-02-20 | パルマトリックス,インコーポレイテッド | チオトロピウム乾燥粉末 |
ITMI20130572A1 (it) * | 2013-04-10 | 2014-10-11 | Eratech Srl | Composizione comprendente almeno due polveri secche ottenute per spray dry per aumentare la stabilita' della formulazione |
ITMI20130571A1 (it) * | 2013-04-10 | 2014-10-11 | Zambon Spa | Composizione farmaceutica contenente budesonide e formoterolo |
PL3021832T3 (pl) | 2013-07-19 | 2021-08-23 | Boehringer Ingelheim Vetmedica Gmbh | Konserwowana ciekła wodna kompozycja farmaceutyczna zawierająca eteryfikowane pochodne cyklodekstryny |
DK2925305T3 (en) | 2013-12-04 | 2016-10-10 | Boehringer Ingelheim Vetmedica Gmbh | Improved pharmaceutical compositions of pimobendan. |
EP4119131A1 (en) | 2014-02-20 | 2023-01-18 | Otitopic Inc. | Dry powder formulations for inhalation |
US9526734B2 (en) | 2014-06-09 | 2016-12-27 | Iceutica Pty Ltd. | Formulation of meloxicam |
KR102603897B1 (ko) | 2014-07-31 | 2023-11-20 | 벡추라 인코포레이티드 | 흡입용 건조 분말 제형 |
MY191712A (en) * | 2014-10-08 | 2022-07-09 | Zambon Spa | Composition comprising at least one dry powder obtained by spray drying to increase the stability of the formulation |
US10449147B2 (en) * | 2014-10-08 | 2019-10-22 | Zambon S.P.A. | Pharmaceutical composition containing budesonide and formoterol |
ES2841933T3 (es) | 2014-10-31 | 2021-07-12 | Univ Monash | Formulación en polvo |
AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
EP3340982B1 (en) | 2015-08-26 | 2021-12-15 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
AU2017290593A1 (en) | 2016-06-27 | 2019-01-03 | Achillion Pharmaceuticals, Inc. | Quinazoline and indole compounds to treat medical disorders |
EP3485215B1 (en) | 2016-07-12 | 2023-06-07 | Alexander Poltorak | System and method for maintaining efficiency of a heat sink |
JP2021519337A (ja) | 2018-03-26 | 2021-08-10 | シー4 セラピューティクス, インコーポレイテッド | Ikarosの分解のためのセレブロン結合剤 |
US20230022157A1 (en) | 2018-08-20 | 2023-01-26 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
CN113365617A (zh) | 2018-10-16 | 2021-09-07 | 乔治亚州立大学研究基金会股份有限公司 | 用于医学疾病治疗的一氧化碳前药 |
KR20200078162A (ko) | 2018-12-21 | 2020-07-01 | 한미약품 주식회사 | 흡입 제형용 건조 분말 및 이의 제조방법 |
KR102330428B1 (ko) | 2019-10-14 | 2021-11-24 | 한미약품 주식회사 | 흡입 제형용 건조 분말 및 이의 제조방법 |
WO2023187393A1 (en) | 2022-03-31 | 2023-10-05 | Hovione Scientia Limited | Inhalation composite and carrier based formulation combination |
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---|---|---|---|---|
GB1381872A (en) | 1971-06-22 | 1975-01-29 | Fisons Ltd | Pharmaceutical compositions for inhalation |
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IT1204826B (it) * | 1986-03-04 | 1989-03-10 | Chiesi Farma Spa | Composizioni farmaceutiche per inalazione |
SE8603812D0 (sv) * | 1986-09-12 | 1986-09-12 | Draco Ab | Administration of liposomes to mammals |
DE3917617A1 (de) | 1989-05-31 | 1990-12-06 | Boehringer Ingelheim Kg | Mikronisierte bioabbaubare partikel, verfahren zur ihrer herstellung und ihre verwendung |
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-
2001
- 2001-06-27 EP EP01947612.6A patent/EP1296651B2/en not_active Expired - Lifetime
- 2001-06-27 WO PCT/GB2001/002860 patent/WO2002000197A1/en active IP Right Grant
- 2001-06-27 EP EP10185471.9A patent/EP2266549B1/en not_active Revoked
- 2001-06-27 IL IL15370501A patent/IL153705A0/xx active IP Right Grant
- 2001-06-27 ES ES01947612T patent/ES2292598T3/es not_active Expired - Lifetime
- 2001-06-27 AT AT01947612T patent/ATE378039T1/de active
- 2001-06-27 PT PT01947612T patent/PT1296651E/pt unknown
- 2001-06-27 EP EP07120591.8A patent/EP1913939B1/en not_active Expired - Lifetime
- 2001-06-27 KR KR1020027017595A patent/KR100949539B1/ko active IP Right Grant
- 2001-06-27 CN CNB018118887A patent/CN100551358C/zh not_active Expired - Lifetime
- 2001-06-27 US US10/312,488 patent/US7744855B2/en not_active Expired - Fee Related
- 2001-06-27 PT PT71205918T patent/PT1913939T/pt unknown
- 2001-06-27 ES ES07120591.8T patent/ES2632461T3/es not_active Expired - Lifetime
- 2001-06-27 DK DK07120591.8T patent/DK1913939T3/en active
-
2002
- 2002-12-26 IL IL153705A patent/IL153705A/en unknown
-
2003
- 2003-09-26 HK HK03106950A patent/HK1056115A1/xx not_active IP Right Cessation
-
2010
- 2010-05-18 US US12/782,283 patent/US9351928B2/en not_active Expired - Lifetime
-
2016
- 2016-05-02 US US15/144,770 patent/US20160243039A1/en not_active Abandoned
-
2017
- 2017-10-31 US US15/799,521 patent/US10561613B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US9351928B2 (en) | 2016-05-31 |
PT1296651E (pt) | 2008-02-12 |
ES2632461T3 (es) | 2017-09-13 |
EP1296651B1 (en) | 2007-11-14 |
US20100285142A1 (en) | 2010-11-11 |
KR20030051439A (ko) | 2003-06-25 |
EP2266549A3 (en) | 2012-01-18 |
US20160243039A1 (en) | 2016-08-25 |
US20030162835A1 (en) | 2003-08-28 |
US20180055772A1 (en) | 2018-03-01 |
CN100551358C (zh) | 2009-10-21 |
EP1296651B2 (en) | 2019-07-17 |
HK1056115A1 (en) | 2004-02-06 |
WO2002000197A1 (en) | 2002-01-03 |
US10561613B2 (en) | 2020-02-18 |
IL153705A (en) | 2011-02-28 |
PT1913939T (pt) | 2017-07-19 |
US7744855B2 (en) | 2010-06-29 |
CN1438875A (zh) | 2003-08-27 |
ES2292598T3 (es) | 2008-03-16 |
KR100949539B1 (ko) | 2010-03-25 |
DK1913939T3 (en) | 2017-09-18 |
EP1913939B1 (en) | 2017-05-31 |
EP2266549B1 (en) | 2019-08-07 |
ATE378039T1 (de) | 2007-11-15 |
EP1296651A1 (en) | 2003-04-02 |
EP2266549A2 (en) | 2010-12-29 |
EP1913939A1 (en) | 2008-04-23 |
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