AU2002220857A1 - Particles for use in a pharmaceutical composition - Google Patents

Particles for use in a pharmaceutical composition

Info

Publication number
AU2002220857A1
AU2002220857A1 AU2002220857A AU2085702A AU2002220857A1 AU 2002220857 A1 AU2002220857 A1 AU 2002220857A1 AU 2002220857 A AU2002220857 A AU 2002220857A AU 2085702 A AU2085702 A AU 2085702A AU 2002220857 A1 AU2002220857 A1 AU 2002220857A1
Authority
AU
Australia
Prior art keywords
particles
pharmaceutical composition
dry powder
additive material
active particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002220857A
Inventor
David Alexander Vodden Morton
John Nicholas Staniforth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vectura Ltd
Original Assignee
Vectura Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27255994&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2002220857(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0029261A external-priority patent/GB0029261D0/en
Priority claimed from GB0030946A external-priority patent/GB0030946D0/en
Priority claimed from GB0124009A external-priority patent/GB0124009D0/en
Application filed by Vectura Ltd filed Critical Vectura Ltd
Publication of AU2002220857A1 publication Critical patent/AU2002220857A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Abstract

The invention provides a method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2µm with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerosolisation of a dry powder in a dry powder inhaler.
AU2002220857A 2000-11-30 2001-11-30 Particles for use in a pharmaceutical composition Abandoned AU2002220857A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0029261.5 2000-11-30
GB0029261A GB0029261D0 (en) 2000-11-30 2000-11-30 Method of making particles for use in a pharmaceutical composition
GB0030946.8 2000-12-19
GB0030946A GB0030946D0 (en) 2000-12-19 2000-12-19 Method of making particles for use in a pharmaceutical composition
GB0124009A GB0124009D0 (en) 2001-10-05 2001-10-05 Particles for use in a pharmaceutical composition
GB0124009.2 2001-10-05
PCT/GB2001/005305 WO2002043700A2 (en) 2000-11-30 2001-11-30 Particles for use in a pharmaceutical composition

Publications (1)

Publication Number Publication Date
AU2002220857A1 true AU2002220857A1 (en) 2002-06-11

Family

ID=27255994

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002220857A Abandoned AU2002220857A1 (en) 2000-11-30 2001-11-30 Particles for use in a pharmaceutical composition

Country Status (8)

Country Link
US (3) US8580306B2 (en)
EP (3) EP2168571B1 (en)
AT (1) ATE446085T1 (en)
AU (1) AU2002220857A1 (en)
DE (1) DE60140268D1 (en)
ES (2) ES2334642T5 (en)
PT (1) PT1337239E (en)
WO (1) WO2002043700A2 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
GB0009469D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
US7744855B2 (en) * 2000-06-27 2010-06-29 Vectura Limited Method of making particles for use in a pharmaceutical composition
ES2334642T5 (en) * 2000-11-30 2016-03-07 Vectura Limited Particles for use in a pharmaceutical composition
WO2002043702A2 (en) † 2000-11-30 2002-06-06 Vectura Limited Pharmaceutical compositions for inhalation
EP2283818B1 (en) 2000-11-30 2017-08-02 Vectura Limited Method of making particles for use in a pharmaceutical composition
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
US20060147389A1 (en) * 2004-04-14 2006-07-06 Vectura Ltd. Devices and pharmaceutical compositions for enhancing dosing efficiency
US20120321717A1 (en) * 2003-04-14 2012-12-20 Vectura Ltd. Devices and pharmaceutical compositions for enhancing dosing efficiency
GB0321607D0 (en) * 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
GB0425758D0 (en) 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
GB0426301D0 (en) * 2004-11-30 2004-12-29 Vectura Ltd Pharmaceutical formulations
GB0525254D0 (en) 2005-12-12 2006-01-18 Jagotec Ag Powder compositions for inhalation
EP1978933A2 (en) * 2005-12-15 2008-10-15 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
GB0712316D0 (en) * 2007-06-26 2007-08-01 Entripneur Ltd A novel powder and its method of manufacture
US9072664B2 (en) 2008-05-22 2015-07-07 3M Innovative Properties Company Process for manufacturing flowable powder drug compositions
WO2009158300A1 (en) 2008-06-26 2009-12-30 3M Innovative Properties Company Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof
WO2010002613A2 (en) 2008-07-02 2010-01-07 3M Innovative Properties Company Method of making a dry powder pharmaceutical composition
LT2400950T (en) 2009-02-26 2019-08-26 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
UA107095C2 (en) * 2009-12-14 2014-11-25 ANTIBIOTIC MICROPARTICLES FOR INHALATION
WO2013153146A1 (en) 2012-04-13 2013-10-17 Glaxosmithkline Intellectual Property Development Limited Aggregate particles
JP5087182B1 (en) * 2012-06-13 2012-11-28 クリニプロ株式会社 Method for producing inhalable powder
US20170333359A1 (en) * 2014-10-20 2017-11-23 Rx Analytic, Inc A drug-containing micro particle
CN107106641B (en) 2014-10-31 2021-12-21 葛兰素史密斯克莱知识产权发展有限公司 Powder formulation
WO2017035408A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
AR106018A1 (en) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc ARYL, HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS
SG11201811491YA (en) 2016-06-27 2019-01-30 Achillion Pharmaceuticals Inc Quinazoline and indole compounds to treat medical disorders
WO2019070693A1 (en) * 2017-10-02 2019-04-11 Board Of Regents, The University Of Texas System Inhalable composition of clofazimine and methods of use
KR20210018199A (en) 2018-03-26 2021-02-17 씨4 테라퓨틱스, 인코포레이티드 Cerevlon binder for decomposition of Ikaros
WO2020041301A1 (en) 2018-08-20 2020-02-27 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
WO2020081723A1 (en) 2018-10-16 2020-04-23 Georgia State University Research Foundation, Inc. Carbon monoxide prodrugs for the treatment of medical disorders

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB124009A (en) 1918-01-12 1919-03-12 Walter Edward Kimber Improvements in and connected with the Manufacture of Tools for Turning, Planing, Boring and similar purposes.
GB1381872A (en) 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
IT1204826B (en) 1986-03-04 1989-03-10 Chiesi Farma Spa INHALATION PHARMACEUTICAL COMPOSITIONS
US5320906A (en) * 1986-12-15 1994-06-14 Vestar, Inc. Delivery vehicles with amphiphile-associated active ingredient
JP2770970B2 (en) * 1987-04-09 1998-07-02 フアイソンズ・ピーエルシー Pharmaceutical composition containing pentamidine
JP2668880B2 (en) 1987-06-23 1997-10-27 日本油脂株式会社 Method for producing coated amino acids
US5190764A (en) 1988-03-03 1993-03-02 Hokko Chemical Industry Co., Ltd. Agent for imparting a sustained release property to a pesticide, a pesticide having a sustained release property and a process for the production thereof
US5223244A (en) 1988-06-20 1993-06-29 Shiseido Company, Ltd. Aerosol composition
US4906476A (en) * 1988-12-14 1990-03-06 Liposome Technology, Inc. Novel liposome composition for sustained release of steroidal drugs in lungs
ES2087911T3 (en) * 1989-04-28 1996-08-01 Riker Laboratories Inc DRY DUST INHALATION DEVICE.
US5188837A (en) * 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
GB9024366D0 (en) 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5413804A (en) * 1991-04-23 1995-05-09 Cacique, Inc. Process for making whey-derived fat substitute product and products thereof
GB2269992A (en) * 1992-08-14 1994-03-02 Rh Ne Poulenc Rorer Limited Powder inhalation formulations
JPH0696517A (en) 1992-09-11 1994-04-08 Matsushita Electric Ind Co Ltd Magnetic disk apparatus
AU660852B2 (en) * 1992-11-25 1995-07-06 Elan Pharma International Limited Method of grinding pharmaceutical substances
US5506203C1 (en) * 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
DE4323636A1 (en) * 1993-07-15 1995-01-19 Hoechst Ag Pharmaceutical preparations from coated, poorly water-soluble pharmaceutical substances for inhalation pharmaceutical forms and processes for their preparation
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
GB9322014D0 (en) 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
DK0748213T3 (en) * 1994-03-07 2004-08-02 Nektar Therapeutics Methods and compositions for pulmonary administration of insulin
US5711934A (en) * 1994-04-11 1998-01-27 Abbott Laboratories Process for the continuous milling of aerosol pharmaceutical formulations in aerosol propellants
US6103271A (en) * 1994-12-02 2000-08-15 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microencapsulation and electrostatic processing method
EE9700138A (en) 1994-12-22 1997-12-15 Astra Aktiebolag Aerosol formulations
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US5612053A (en) * 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
US5635160A (en) * 1995-06-07 1997-06-03 The University Of North Carolina At Chapel Hill Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
US5931809A (en) * 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
DE19645359A1 (en) * 1996-11-04 1998-05-07 Bayer Ag Process for the preparation of alkylhalosilanes
AU1251999A (en) * 1997-12-03 1999-06-16 Britannia Pharmaceuticals Limited Improvements in medicaments for asthma treatment
US6178414B1 (en) * 1997-12-16 2001-01-23 Nortel Networks Limited Method and apparatus for updating and searching an ordered list of values stored within a memory resource
US6086376A (en) 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
US7521068B2 (en) * 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
HU226164B1 (en) 1998-11-13 2008-05-28 Jagotec Ag Use of magnesium stearate in dry powder compositions suitable for inhalation and compositions suitable for inhalation
US6984404B1 (en) 1998-11-18 2006-01-10 University Of Florida Research Foundation, Inc. Methods for preparing coated drug particles and pharmaceutical formulations thereof
JP2003516926A (en) 1998-11-18 2003-05-20 ユニバーシティ オブ フロリダ Method for preparing coated drug particles and pharmaceutical formulations thereof
GB9826783D0 (en) 1998-12-04 1999-01-27 Scherer Ltd R P Inhalation powders
GB9827145D0 (en) 1998-12-09 1999-02-03 Co Ordinated Drug Dev Improvements in or relating to powders
US6542490B1 (en) * 1999-01-29 2003-04-01 Nortel Networks Limited Data link control proctocol for 3G wireless system
BR9917246A (en) 1999-03-05 2002-03-26 Chiesi Farma Spa Advanced pharmaceutical compositions for inhalation powder
IT1309592B1 (en) 1999-03-05 2002-01-24 Chiesi Farma Spa VEHICLE PARTICLES MODIFIED FOR USE IN THE PREPARATION OF PHARMACEUTICAL FORMULATIONS IN THE FORM OF POLYMERS FOR INHALATION AND
ATE233084T1 (en) * 1999-04-14 2003-03-15 Glaxo Group Ltd PHARMACEUTICAL AEROSOL FORMULATION
US6406745B1 (en) 1999-06-07 2002-06-18 Nanosphere, Inc. Methods for coating particles and particles produced thereby
ITMI991582A1 (en) 1999-07-16 2001-01-16 Chiesi Farma Spa DUST CONSTITUTED FROM PARTICLES HAVING THE PERFECTLY SMOOTH SURFACE FOR USE AS VEHICLES FOR THE PREPARATION OF INALA MIXTURES
US6197369B1 (en) * 1999-09-30 2001-03-06 New Jersey Institute Of Technology Method of particle coating
GB0008660D0 (en) 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
PE20011227A1 (en) * 2000-04-17 2002-01-07 Chiesi Farma Spa PHARMACEUTICAL FORMULATIONS FOR DRY POWDER INHALERS IN THE FORM OF HARD AGGLOMERATES
GB0009469D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
GB0009468D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
US7744855B2 (en) * 2000-06-27 2010-06-29 Vectura Limited Method of making particles for use in a pharmaceutical composition
US6404772B1 (en) * 2000-07-27 2002-06-11 Symbol Technologies, Inc. Voice and data wireless communications network and method
HUP0302311A3 (en) 2000-10-09 2006-07-28 3M Innovative Properties Co Medicinal aerosol formulations
TR200402367T4 (en) 2000-10-12 2004-12-21 Boehringer Ingelheim Pharma Gmbh& Co.Kg Inhalation powders containing new tiotropium
ES2334642T5 (en) 2000-11-30 2016-03-07 Vectura Limited Particles for use in a pharmaceutical composition
GB0124009D0 (en) 2001-10-05 2001-11-28 Vectura Ltd Particles for use in a pharmaceutical composition
EP2283818B1 (en) * 2000-11-30 2017-08-02 Vectura Limited Method of making particles for use in a pharmaceutical composition
US20060147389A1 (en) 2004-04-14 2006-07-06 Vectura Ltd. Devices and pharmaceutical compositions for enhancing dosing efficiency
GB0321607D0 (en) 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
WO2005025535A2 (en) 2003-09-15 2005-03-24 Vectura Limited Methods for preparing pharmaceutical compositions

Also Published As

Publication number Publication date
EP2292212A3 (en) 2012-08-08
EP2168571A3 (en) 2011-11-16
US8580306B2 (en) 2013-11-12
US20140037737A1 (en) 2014-02-06
WO2002043700A3 (en) 2002-10-24
EP1337239B2 (en) 2015-11-25
ES2334642T5 (en) 2016-03-07
ES2689704T3 (en) 2018-11-15
EP2168571B1 (en) 2018-08-22
EP2292212A2 (en) 2011-03-09
PT1337239E (en) 2010-01-26
EP2168571A2 (en) 2010-03-31
DE60140268D1 (en) 2009-12-03
US10238601B2 (en) 2019-03-26
WO2002043700A2 (en) 2002-06-06
ATE446085T1 (en) 2009-11-15
EP1337239B1 (en) 2009-10-21
US20040071635A1 (en) 2004-04-15
ES2334642T3 (en) 2010-03-15
US20170216202A1 (en) 2017-08-03
US9585839B2 (en) 2017-03-07
EP1337239A2 (en) 2003-08-27

Similar Documents

Publication Publication Date Title
EP2292212A3 (en) Method of making particles for use in a pharmaceutical composition
WO2002043702A3 (en) Pharmaceutical compositions for inhalation
MY132999A (en) New formulation for inhalation
AU2002316820A1 (en) Powder inhaler formulations
AU2001279631A1 (en) Self-emulsifying active substance formulation and use of this formulation
AU2001236207A1 (en) Powder formulation
HUP0202062A2 (en) Method for making granules with masked taste and instant release of the active particle
HUP0300593A2 (en) Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
CA2375055A1 (en) Sulfur-containing fertilizer composition and method for preparing same
AU2003242563A1 (en) A terpene-based composition of substances, a method for its preparation and a method for its dispersal into the atmosphere
TNSN05046A1 (en) Method of preparing dry powder inhalation compositions
CA2461517A1 (en) Nicotine formulations comprising cocoa and use thereof
WO2005044221A3 (en) Solid active ingredient formulation
AU2001293900A1 (en) Combination particles for the treatment of asthma
CA2277890A1 (en) New formulation for inhalation having a poured bulk density of from 0.28 to 0.38 g/ml, comprising formoterol
EP1238662A3 (en) Method for manufacturing drug granules, the drug granules and pharmaceutical preparation containing the drug granules
ATE293957T1 (en) METHOD FOR PRODUCING INHALATION POWDERS
WO2003000240A3 (en) Stable powder inhalation dosage formulation
IL161983A0 (en) Preparation compositions containing acid-unstable physiologically active compounds, and process for producing the same
WO2003090715A3 (en) Particulate materials
HK1048064A1 (en) Suspension of an epi-hne protein, process of preparation thereof, dry powder aerosol derived therefrom, pharmaceutical compositions containing said suspension or aerosol, and their uses
WO2002015880A3 (en) Powdered mannitol and mannitol-containing compositions
WO2005041922A3 (en) Composition
AU6389301A (en) Shaped body containing organic-inorganic hybrid materials, the production thereof and the use of the same for selectively oxidizing hydrocarbons
SI1186292T1 (en) Dry carotinoid powder with a mulit-core structure