IL153682A0 - Variolin derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Variolin derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL153682A0
IL153682A0 IL15368201A IL15368201A IL153682A0 IL 153682 A0 IL153682 A0 IL 153682A0 IL 15368201 A IL15368201 A IL 15368201A IL 15368201 A IL15368201 A IL 15368201A IL 153682 A0 IL153682 A0 IL 153682A0
Authority
IL
Israel
Prior art keywords
sub
substituted
group
unsubstituted
variolin
Prior art date
Application number
IL15368201A
Other languages
English (en)
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0017055A external-priority patent/GB0017055D0/en
Priority claimed from GB0030689A external-priority patent/GB0030689D0/en
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of IL153682A0 publication Critical patent/IL153682A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL15368201A 2000-07-11 2001-07-11 Variolin derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same IL153682A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0017055A GB0017055D0 (en) 2000-07-11 2000-07-11 Synthesis
GB0030689A GB0030689D0 (en) 2000-12-15 2000-12-15 Synthesis
PCT/GB2001/003111 WO2002004447A1 (en) 2000-07-11 2001-07-11 Variolin derivatives as anti-cancer agents

Publications (1)

Publication Number Publication Date
IL153682A0 true IL153682A0 (en) 2003-07-06

Family

ID=26244637

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15368201A IL153682A0 (en) 2000-07-11 2001-07-11 Variolin derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL153682A IL153682A (en) 2000-07-11 2002-12-26 History of variolins, processes for their preparation and pharmaceutical preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL153682A IL153682A (en) 2000-07-11 2002-12-26 History of variolins, processes for their preparation and pharmaceutical preparations containing them

Country Status (20)

Country Link
US (1) US7320981B2 (enExample)
EP (1) EP1299388B1 (enExample)
JP (1) JP2004502773A (enExample)
KR (1) KR100886161B1 (enExample)
CN (1) CN1324028C (enExample)
AT (1) ATE431349T1 (enExample)
AU (3) AU2001270783B2 (enExample)
BR (1) BR0112413A (enExample)
CA (1) CA2414200C (enExample)
CY (1) CY1109283T1 (enExample)
DE (1) DE60138707D1 (enExample)
DK (1) DK1299388T3 (enExample)
ES (1) ES2327210T3 (enExample)
IL (2) IL153682A0 (enExample)
MX (1) MXPA03000341A (enExample)
NZ (1) NZ523491A (enExample)
PT (1) PT1299388E (enExample)
RU (1) RU2299884C2 (enExample)
SI (1) SI1299388T1 (enExample)
WO (1) WO2002004447A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0019117D0 (en) * 2000-08-03 2000-09-27 Univ Barcelona Derivatives of variolin B
GB0116966D0 (en) * 2001-07-11 2001-09-05 Pharma Mar Sa Anittumoral compounds
CA2526285A1 (en) 2003-05-15 2004-12-23 Arqule, Inc. Inhibitors of p38 and methods of using the same
US7829560B2 (en) 2004-07-08 2010-11-09 Arqule, Inc. 1,4-disubstituted naphthalenes as inhibitors of P38 MAP kinase
US8178672B2 (en) 2004-10-19 2012-05-15 Arqule, Inc. Synthesis of imidazooxazole and imidazothiazole inhibitors of p38 MAP kinase
EP1666467A1 (en) * 2004-11-08 2006-06-07 Evotec AG 11Beta-HSD1 Inhibitors
WO2006075591A1 (ja) * 2005-01-12 2006-07-20 Kuraray Co., Ltd. 樹脂組成物及びそれからなるフィルム
PL1896470T3 (pl) * 2005-05-16 2011-03-31 Irm Llc Pochodne pirolopirydynowe jako inhibitory kinazy białkowej
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ236494A3 (en) * 1992-04-03 1994-12-15 Upjohn Co Pharmaceutically active bicyclic-heterocyclic amines
GB0019117D0 (en) * 2000-08-03 2000-09-27 Univ Barcelona Derivatives of variolin B
GB0116966D0 (en) 2001-07-11 2001-09-05 Pharma Mar Sa Anittumoral compounds

Also Published As

Publication number Publication date
KR100886161B1 (ko) 2009-02-27
RU2299884C2 (ru) 2007-05-27
SI1299388T1 (sl) 2009-12-31
MXPA03000341A (es) 2004-04-05
AU2001270783B2 (en) 2006-06-15
KR20030017581A (ko) 2003-03-03
AU2006213946A1 (en) 2006-10-05
ES2327210T3 (es) 2009-10-27
EP1299388B1 (en) 2009-05-13
BR0112413A (pt) 2003-05-27
CA2414200A1 (en) 2002-01-17
DE60138707D1 (de) 2009-06-25
WO2002004447A1 (en) 2002-01-17
US20050014778A1 (en) 2005-01-20
AU2006213946B2 (en) 2008-01-10
CA2414200C (en) 2010-05-04
AU7078301A (en) 2002-01-21
ATE431349T1 (de) 2009-05-15
PT1299388E (pt) 2009-08-13
CN1630658A (zh) 2005-06-22
DK1299388T3 (da) 2009-08-31
CY1109283T1 (el) 2014-07-02
CN1324028C (zh) 2007-07-04
EP1299388A1 (en) 2003-04-09
IL153682A (en) 2010-05-31
US7320981B2 (en) 2008-01-22
NZ523491A (en) 2004-06-25
JP2004502773A (ja) 2004-01-29

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