IL153674A0 - 13-substituted methacycline compounds - Google Patents

13-substituted methacycline compounds

Info

Publication number
IL153674A0
IL153674A0 IL15367401A IL15367401A IL153674A0 IL 153674 A0 IL153674 A0 IL 153674A0 IL 15367401 A IL15367401 A IL 15367401A IL 15367401 A IL15367401 A IL 15367401A IL 153674 A0 IL153674 A0 IL 153674A0
Authority
IL
Israel
Prior art keywords
compounds
substituted methacycline
methacycline compounds
substituted
methods
Prior art date
Application number
IL15367401A
Other languages
English (en)
Original Assignee
Tufts College
Paratek Pharm Innc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts College, Paratek Pharm Innc filed Critical Tufts College
Publication of IL153674A0 publication Critical patent/IL153674A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL15367401A 2000-07-07 2001-06-29 13-substituted methacycline compounds IL153674A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21658000P 2000-07-07 2000-07-07
PCT/US2001/020716 WO2002004405A2 (en) 2000-07-07 2001-06-29 13-substituted methacycline compounds

Publications (1)

Publication Number Publication Date
IL153674A0 true IL153674A0 (en) 2003-07-06

Family

ID=22807633

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15367401A IL153674A0 (en) 2000-07-07 2001-06-29 13-substituted methacycline compounds

Country Status (16)

Country Link
EP (3) EP1301465A2 (hu)
JP (1) JP2004502751A (hu)
KR (1) KR20030017609A (hu)
CN (1) CN1452611A (hu)
AT (2) ATE465989T1 (hu)
AU (1) AU2001271616A1 (hu)
BR (1) BR0112268A (hu)
CA (1) CA2415172A1 (hu)
CZ (1) CZ2003332A3 (hu)
DE (1) DE60141994D1 (hu)
EA (1) EA200300136A1 (hu)
HR (1) HRP20030092A2 (hu)
HU (1) HUP0301429A2 (hu)
IL (1) IL153674A0 (hu)
MX (1) MXPA03000036A (hu)
WO (1) WO2002004405A2 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2553510C (en) 2004-01-15 2012-09-25 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
CA2585418A1 (en) 2004-10-25 2006-05-04 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
CN101967108B (zh) * 2010-09-13 2013-06-19 苏春华 一种美他环素的衍生物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
US2980584A (en) 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US3062717A (en) 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3165531A (en) 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3183267A (en) * 1962-09-06 1965-05-11 Pfizer & Co C 6-methylenetetracycline derivatives
GB1108310A (en) * 1964-04-30 1968-04-03 Pfizer & Co C Derivatives of 6-methylene-tetracycline and process for their preparation
US3454697A (en) 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (hu) 1966-05-31 1967-12-01
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
DE60027465T2 (de) 1999-09-14 2007-02-01 The Trustees Of Tufts College, Medford Verfahren zur herstellung von substituierten tetracyclinen mit hilfe von auf übergangsmetalle basierten chemien

Also Published As

Publication number Publication date
CN1452611A (zh) 2003-10-29
AU2001271616A1 (en) 2002-01-21
MXPA03000036A (es) 2003-07-14
ATE526308T1 (de) 2011-10-15
EP1661883A1 (en) 2006-05-31
WO2002004405A2 (en) 2002-01-17
EP1661883B1 (en) 2010-04-28
DE60141994D1 (de) 2010-06-10
WO2002004405A3 (en) 2002-03-14
ATE465989T1 (de) 2010-05-15
CA2415172A1 (en) 2002-01-17
EP1301465A2 (en) 2003-04-16
JP2004502751A (ja) 2004-01-29
KR20030017609A (ko) 2003-03-03
EP2204361A1 (en) 2010-07-07
EA200300136A1 (ru) 2003-06-26
BR0112268A (pt) 2003-05-27
CZ2003332A3 (cs) 2003-05-14
EP2204361B1 (en) 2011-09-28
HUP0301429A2 (hu) 2003-09-29
HRP20030092A2 (en) 2004-06-30

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