US1880441A
(en)
|
|
1932-10-04 |
|
Etjbole m |
US2467692A
(en)
|
|
1949-04-19 |
|
Naphthyridones and processes fob |
DE282711C
(en)
|
|
|
|
|
BE628255A
(en)
|
|
|
|
|
US1895105A
(en)
|
|
1933-01-24 |
|
Cubt bath |
US932290A
(en)
|
1908-03-24 |
1909-08-24 |
Basf Ag |
Compound of the anthracene series and process of making same.
|
US1001325A
(en)
|
1910-11-02 |
1911-08-22 |
Agfa Ag |
Product of the anthraquinone series and process of making same.
|
US1253252A
(en)
|
1914-04-15 |
1918-01-15 |
Basf Ag |
Bluish-green vat dyes and process of making them.
|
US2593798A
(en)
|
1947-05-22 |
1952-04-22 |
Searle & Co |
Aminoalkylamino isoquinoline compounds
|
US2612503A
(en)
|
1949-04-19 |
1952-09-30 |
Smith Kline French Lab |
Basic ether-substituted isoquinolines
|
US2638472A
(en)
|
1949-08-26 |
1953-05-12 |
Hoffmann La Roche |
1-benzyl-5, 6, 7, 8-tetrahydroisoquinoline and derivatives thereof
|
US2666059A
(en)
|
1950-08-11 |
1954-01-12 |
American Cyanamid Co |
Anilinoisoquinolines and processes of preparing the same
|
US2700040A
(en)
|
1951-05-21 |
1955-01-18 |
Smith Kline French Lab |
Aminoalkylaminoisoquinolines
|
DE963184C
(en)
|
1955-07-24 |
1957-05-02 |
Cassella Farbwerke Mainkur Ag |
Process for the preparation of durable solutions of salts of 1-dialkylaminoalkoxy-3-alkyl-isoquinolines
|
GB810108A
(en)
|
1955-09-13 |
1959-03-11 |
Cassella Farbwerke Mainkur Ag |
Phthalazine compounds basically substituted in the 1-position
|
US2892841A
(en)
|
1956-04-02 |
1959-06-30 |
Grace W R & Co |
Process for aminating nitrogen-containing heterocyclic compounds
|
GB838994A
(en)
|
1956-12-05 |
1960-06-22 |
Ici Ltd |
New anthradipyridazones and their use in polymeric materials
|
US2992220A
(en)
|
1956-12-05 |
1961-07-11 |
Ici Ltd |
New anthra-1':9'(n):10'(n):5'-dipyridazones and anthra-1':9'(n):10'(n):4'-dipyridazones chemical compounds
|
US3247212A
(en)
|
1963-03-19 |
1966-04-19 |
Dow Chemical Co |
Thio substituted 3 amino isoquinolines
|
US3291801A
(en)
|
1963-05-23 |
1966-12-13 |
Grace W R & Co |
Novel octahydro-6(5)-phenanthridinones and preparation thereof
|
US3300499A
(en)
|
1964-01-27 |
1967-01-24 |
Sterling Drug Inc |
4-alkyl (or alkenyl)-1, 4-dihydro-1-oxobenzo [f] [1, 7] naphthyridine 2-carboxylic acid derivatives
|
CH461002A
(en)
|
1965-08-11 |
1968-08-15 |
Ciba Geigy |
Process for the preparation of basic water-soluble dyes
|
US3403157A
(en)
|
1965-09-01 |
1968-09-24 |
American Home Prod |
Benzo[6, 7]cyclohepta[1, 2, 3-d, e]isoquinoline derivatives
|
CH463778A
(en)
|
1965-10-12 |
1968-10-15 |
Sandoz Ag |
Process for increasing the lightfastness of organic non-textile materials
|
DE1644596A1
(en)
|
1965-11-16 |
1971-05-06 |
Bayer Ag |
Dyes and processes for their preparation
|
US3557119A
(en)
|
1967-04-11 |
1971-01-19 |
American Home Prod |
2,3,7,8,9,9a-hexahydro-1h-benzo(d,e)(1,7) naphthyridine derivatives
|
GB1173227A
(en)
|
1967-06-22 |
1969-12-03 |
Koninklijke Pharma Fab Nv |
Amino-Isoquinolines
|
US3830816A
(en)
|
1968-03-09 |
1974-08-20 |
Aspro Nicholas Ltd |
1-cyclopropylmethyleneamino-3,4-dihydroisoquinoline and acid addition salts thereof
|
US3573304A
(en)
|
1968-12-03 |
1971-03-30 |
Delalande Sa |
1-dimethylamino - 3 - methyl-2(pyridyl or pyridazinyl) pentane and the corresponding non-toxic acid addition salts thereof
|
US3904671A
(en)
|
1969-04-01 |
1975-09-09 |
Sterling Drug Inc |
Esters of 3-(hydroxy or hydroxymethyl)-4-hydroxyphenyl aminomethyl ketones
|
BE755131A
(en)
|
1969-08-22 |
1971-02-22 |
Merck Patent Gmbh |
1,2,3,11B-TETRAHYDROPYRIDO / 3,4,5: M, N / THIOXANTHENES, THEIR ACID ADDITIONAL SALTS AND THEIR PREPARATION METHODS
|
FR2081572B1
(en)
|
1970-03-12 |
1973-04-06 |
Rhone Poulenc Sa |
|
ZA711512B
(en)
|
1970-03-14 |
1971-12-29 |
Aspro Nicholas Ltd |
Heterocyclic derivatives and pharmaceutical compositions thereof
|
US3700673A
(en)
|
1971-02-12 |
1972-10-24 |
Morton Norwich Products Inc |
3-4-dihydrobenzo(b) (1,7)naphthyridin-1(2h)-ones
|
US3723436A
(en)
|
1971-02-25 |
1973-03-27 |
Sun Oil Co |
Process for aromatic lactams
|
USRE31617E
(en)
|
1972-02-04 |
1984-06-26 |
Bristol-Myers Company |
Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
|
US3838134A
(en)
|
1972-04-03 |
1974-09-24 |
G Gauthier |
Phenanthridinones as antiviral agents
|
GB1379111A
(en)
|
1972-04-13 |
1975-01-02 |
Aspro Nicholas Ltd |
Preparation of fused-ring pyridine and pyrazine derivatives
|
CA1000701A
(en)
|
1972-07-19 |
1976-11-30 |
Leslie G. Humber |
Process for preparing hexahydrobenzo (6,7) cyclohepta(1,2,3-de)isoquinolines
|
DE2355084A1
(en)
|
1972-11-06 |
1974-05-16 |
Guidotti & C Spa Labor |
COMPOUNDS HAVING A GASTIC ACID SECRETION-INHIBITING EFFECT AND PROCESS FOR THEIR PRODUCTION
|
US4169897A
(en)
|
1972-12-21 |
1979-10-02 |
Richardson-Merrell Inc. |
2,7-bis-basic ethers of 9-phenanthrol and 9-loweralkoxy phenanthrol
|
US3899529A
(en)
|
1973-02-22 |
1975-08-12 |
Merck & Co Inc |
Aroyl substituted naphthalene acetic acids
|
ZA743332B
(en)
|
1973-06-22 |
1975-05-28 |
Aspro Nicholas Ltd |
Pharmacologically active phthalazine derivatives
|
CH581113A5
(en)
|
1973-10-08 |
1976-10-29 |
Sandoz Ag |
|
US3978066A
(en)
|
1973-11-06 |
1976-08-31 |
Ayerst, Mckenna And Harrison Ltd. |
Certain 4,6-dihydropyrrolotriazoline-quinoline derivatives
|
US3900477A
(en)
|
1973-11-06 |
1975-08-19 |
Ayerst Mckenna & Harrison |
5-amino-and 5-hydrazinodihydropyrroloisoquinoline derivatives
|
US3950343A
(en)
|
1973-11-06 |
1976-04-13 |
Ayerst, Mckenna And Harrison Ltd. |
Pyrroloisoquinoline derivatives
|
US3932643A
(en)
|
1974-01-07 |
1976-01-13 |
Pfizer Inc. |
Phenanthridines and phenanthridinones as antiviral agents
|
US4031097A
(en)
|
1974-09-09 |
1977-06-21 |
Eli Lilly And Company |
Descarboxylysergic acid
|
US3991064A
(en)
|
1975-01-17 |
1976-11-09 |
Warner-Lambert Company |
Benzonaphthyridines
|
BE839967R
(en)
|
1975-03-26 |
1976-09-24 |
|
NEW ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
|
DE2557555C2
(en)
|
1975-12-20 |
1986-04-17 |
Hoechst Ag, 6230 Frankfurt |
Disazo compounds, process for their preparation and their use as pigments
|
GB1545767A
(en)
|
1976-06-30 |
1979-05-16 |
Aspro Nicholas Ltd |
Isoquinoline derivatives
|
JPS5337696A
(en)
|
1976-08-26 |
1978-04-06 |
Omnium Chimique Sa |
Hexahydrocantinonee6 derivative
|
DE2650226A1
(en)
|
1976-11-02 |
1978-05-11 |
Henkel Kgaa |
1,3,4-Tri:amino-isoquinoline hair dye coupler and developer - prepd. by hydrogenating 1,3-di:amino-4-nitroso-isoquinoline using a palladium catalyst
|
DE2818403A1
(en)
|
1978-04-27 |
1979-11-08 |
Hoechst Ag |
NEW ISOCHINOL DERIVATIVES AND METHOD FOR THEIR PRODUCTION
|
US4309543A
(en)
|
1980-03-17 |
1982-01-05 |
Dynapol |
Process for preparing cyclic amides
|
DE3025385A1
(en)
|
1980-07-04 |
1982-01-28 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
NEW TRICYCLIC ARYL ETHERS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
|
US4472401A
(en)
|
1981-11-27 |
1984-09-18 |
Roussel Uclaf |
Pyrimido-quinoxalines having antiallergic properties
|
US4594415A
(en)
|
1982-03-29 |
1986-06-10 |
Robins Roland K |
Azole dinucleotide compositions and methods of use
|
IT1229075B
(en)
|
1985-04-05 |
1991-07-17 |
Fidia Farmaceutici |
Topical compsn. contg. hyaluronic acid deriv. as vehicle
|
US4757128A
(en)
|
1986-08-01 |
1988-07-12 |
Massachusetts Institute Of Technology |
High molecular weight polyanhydride and preparation thereof
|
ES532317A0
(en)
|
1983-05-16 |
1985-11-16 |
Merck & Co Inc |
A PHARMACEUTICAL COMPOSITION
|
DE3332633A1
(en)
|
1983-09-09 |
1985-04-04 |
Luitpold-Werk Chemisch-pharmazeutische Fabrik GmbH & Co, 8000 München |
Substituted carboxylic acid derivatives, process for their preparation, and pharmaceuticals
|
US4639454A
(en)
|
1985-01-17 |
1987-01-27 |
E. I. Du Pont De Nemours And Company |
Phenylquinazolinecarboxylic acids and derivatives as cancer chemotherapeutic agents
|
US4742171A
(en)
|
1985-03-13 |
1988-05-03 |
Hoechst-Roussel Pharmaceuticals Inc. |
Method of synthesizing 1,4-dihydro-benzo[c]-1,5-naphthyridin-2(3H)-ones
|
US5032617A
(en)
|
1985-05-03 |
1991-07-16 |
Sri International |
Substituted benzamide radiosensitizers
|
US5215738A
(en)
|
1985-05-03 |
1993-06-01 |
Sri International |
Benzamide and nicotinamide radiosensitizers
|
US5041653A
(en)
|
1985-05-03 |
1991-08-20 |
Sri International |
Substituted benzamide radiosensitizers
|
US4713244A
(en)
|
1985-08-16 |
1987-12-15 |
Bausch & Lomb Incorporated |
Sustained-release formulation containing an amino acid polymer with a lower alkyl (C1 -C4) polar solvent
|
US4668506A
(en)
|
1985-08-16 |
1987-05-26 |
Bausch & Lomb Incorporated |
Sustained-release formulation containing and amino acid polymer
|
EP0270306B1
(en)
|
1986-12-01 |
1991-03-27 |
Sumitomo Chemical Company, Limited |
Anthrapyridone compounds, their production process and their use
|
US4740581A
(en)
|
1987-02-24 |
1988-04-26 |
Eastman Kodak Company |
Condensation copolymers containing copolymerized isoquinoline derivative colorants and products therefrom
|
US5480631A
(en)
|
1987-11-19 |
1996-01-02 |
Vanderbilt University |
Radioiodinated benzamines and method of their use as radioimaging
|
US4925968A
(en)
|
1987-12-23 |
1990-05-15 |
American Home Products Corporation |
N-acyl-N-naphthoylglycines as aldose reductase inhibitors
|
US5274097A
(en)
|
1988-04-19 |
1993-12-28 |
Bayer Aktiengesellschaft |
1,3-disubstituted pyrrolidines
|
US5177075A
(en)
*
|
1988-08-19 |
1993-01-05 |
Warner-Lambert Company |
Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
|
US4902695A
(en)
|
1989-02-13 |
1990-02-20 |
Eli Lilly And Company |
Excitatory amino acid receptor antagonists
|
GB8908229D0
(en)
|
1989-04-12 |
1989-05-24 |
Smithkline Beckman Intercredit |
Compounds
|
US5665710A
(en)
|
1990-04-30 |
1997-09-09 |
Georgetown University |
Method of making liposomal oligodeoxynucleotide compositions
|
US5719151A
(en)
|
1990-05-04 |
1998-02-17 |
Shall; Sydney |
Substituted benzene compounds
|
US5077035A
(en)
|
1990-05-14 |
1991-12-31 |
The University Of Michigan |
Radioiodinated benzovesamicol analogs for cholinergic nerve mapping
|
US5633282A
(en)
|
1990-05-25 |
1997-05-27 |
British Technology Group Limited |
Inhibition of viral infection
|
US5635506A
(en)
|
1990-06-26 |
1997-06-03 |
Research Corporation Technologies, Inc. |
1, 2-dihydro-3H-dibenzisoquinoline-1,3-dione anticancer agents
|
SE466693B
(en)
|
1990-07-26 |
1992-03-23 |
Volvo Ab |
DEVICE FOR SELECTIVE CLIMATE CONTROL IN VEHICLE CUP
|
US5482975A
(en)
|
1991-10-22 |
1996-01-09 |
Octamer, Inc. |
Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents and anti-tumor agents
|
US5652260A
(en)
|
1991-10-22 |
1997-07-29 |
Octamer, Inc. |
Adenosine diphosphoribose polymerase binding nitroso aromatic compound useful as retroviral inactivating agents, anti-retroviral agents and anti-tumor agents
|
US5516941A
(en)
|
1991-10-22 |
1996-05-14 |
Octamer, Inc. |
Specific inactivators of "retroviral" (asymmetric) zinc fingers
|
US5464871A
(en)
|
1993-05-12 |
1995-11-07 |
Octamer, Inc. |
Aromatic nitro and nitroso compounds and their metabolites useful as anti-viral and anti-tumor agents
|
US5473074A
(en)
|
1991-10-22 |
1995-12-05 |
Octamer, Incorporated |
Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents and anti-tumor agents-54
|
US5264220A
(en)
|
1991-11-12 |
1993-11-23 |
Long David M Jr |
Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents
|
JP2989953B2
(en)
|
1992-02-10 |
1999-12-13 |
富士ゼロックス株式会社 |
Fixing device and fixing endless belt
|
US5235045A
(en)
|
1992-03-19 |
1993-08-10 |
Microbiomed Corporation |
Non-azo naphthalimide dyes
|
US5414001A
(en)
|
1992-05-29 |
1995-05-09 |
American Cyanamid Company |
Antineoplastic pyrrolo[4,3,2-de]quinolin-8(1H)-ones
|
JP3205402B2
(en)
|
1992-09-09 |
2001-09-04 |
東芝アイティー・コントロールシステム株式会社 |
Method and apparatus for determining crystal orientation
|
US5391554A
(en)
*
|
1992-09-09 |
1995-02-21 |
Warner-Lambert Company |
Dihydro- and tetrahydronaphthyridines
|
US5262564A
(en)
|
1992-10-30 |
1993-11-16 |
Octamer, Inc. |
Sulfinic acid adducts of organo nitroso compounds useful as retroviral inactivating agents anti-retroviral agents and anti-tumor agents
|
US5338851A
(en)
|
1993-03-31 |
1994-08-16 |
Eli Lilly And Company |
Synthesis of cis-decahydroisoquinoline-3-carboxylic acids
|
IT1265340B1
(en)
|
1993-07-14 |
1996-11-22 |
Istituto Biochimico Italiano |
SUBSTANCES INHIBITING PROTEIN ADP-RIBOSYLATION SUITABLE FOR THE PREVENTION OF COMPLICATIONS OF DIABETES MELLITUS.
|
US5587384A
(en)
*
|
1994-02-04 |
1996-12-24 |
The Johns Hopkins University |
Inhibitors of poly(ADP-ribose) synthetase and use thereof to treat NMDA neurotoxicity
|
US5434188A
(en)
|
1994-03-07 |
1995-07-18 |
Warner-Lambert Company |
1-ether and 1-thioether-naphthalene-2-carboxamides as inhibitors of cell adhesion and as inhibitors of the activation of HIV
|
GB9404485D0
(en)
|
1994-03-09 |
1994-04-20 |
Cancer Res Campaign Tech |
Benzamide analogues
|
US5395835A
(en)
|
1994-03-24 |
1995-03-07 |
Warner-Lambert Company |
Naphthalamides as central nervous system agents
|
EP0676201B1
(en)
|
1994-04-05 |
2002-09-11 |
Universiteit van Pretoria |
Use of a riminophenazine for treating MDR resistance
|
US5703089A
(en)
|
1994-04-28 |
1997-12-30 |
Knoll Aktiengesellschaft |
Dihydrodibenzisoquinolinediones
|
US5589483A
(en)
|
1994-12-21 |
1996-12-31 |
Geron Corporation |
Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat skin diseases associated with cellular senescence
|
US5659082A
(en)
|
1995-04-03 |
1997-08-19 |
Centaur Pharmaceuticals, Inc. |
Nitro- and aminobenzamide compounds for neurodegenerative disorders
|
US5656638A
(en)
|
1995-04-18 |
1997-08-12 |
Geron Corporation |
Telomerase inhibitors
|
US5760062A
(en)
|
1995-04-18 |
1998-06-02 |
Geron Corporation |
Telomerase inhibitors
|
US5703116A
(en)
|
1995-04-18 |
1997-12-30 |
Geron Corporation |
Telomerase Inhibitors
|
US5618813A
(en)
|
1995-05-26 |
1997-04-08 |
Abbott Laboratories |
Benzo[5.6]pyrano[2.3.4-ij]quinolizine and benzo[5.6]thiopyrano[2.3.4-ij]quinolizine derivatives as antibacterial and antineoplastic agents
|
US5767135A
(en)
|
1995-12-29 |
1998-06-16 |
Fernandez-Pol; Jose Alberto |
Antiviral agent
|
US6197785B1
(en)
|
1997-09-03 |
2001-03-06 |
Guilford Pharmaceuticals Inc. |
Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity
|
US6235748B1
(en)
|
1997-09-03 |
2001-05-22 |
Guilford Pharmaceuticals Inc. |
Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
|
US6121278A
(en)
|
1997-09-03 |
2000-09-19 |
Guilford Pharmaceuticals, Inc. |
Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity
|
US6201020B1
(en)
|
1998-12-31 |
2001-03-13 |
Guilford Pharmaceuticals, Inc. |
Ortho-diphenol compounds, methods and pharmaceutical compositions for inhibiting parp
|