IL152770A0 - Gabapentin analogues for sleep disorders - Google Patents

Gabapentin analogues for sleep disorders

Info

Publication number
IL152770A0
IL152770A0 IL15277001A IL15277001A IL152770A0 IL 152770 A0 IL152770 A0 IL 152770A0 IL 15277001 A IL15277001 A IL 15277001A IL 15277001 A IL15277001 A IL 15277001A IL 152770 A0 IL152770 A0 IL 152770A0
Authority
IL
Israel
Prior art keywords
sleep disorders
gabapentin analogues
gabapentin
analogues
compounds
Prior art date
Application number
IL15277001A
Other languages
English (en)
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL152770A0 publication Critical patent/IL152770A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15277001A 2000-06-26 2001-05-18 Gabapentin analogues for sleep disorders IL152770A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21417100P 2000-06-26 2000-06-26
PCT/US2001/016343 WO2002000209A2 (en) 2000-06-26 2001-05-18 Gabapentin analogues for sleep disorders

Publications (1)

Publication Number Publication Date
IL152770A0 true IL152770A0 (en) 2003-06-24

Family

ID=22798045

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15277001A IL152770A0 (en) 2000-06-26 2001-05-18 Gabapentin analogues for sleep disorders
IL152770A IL152770A (en) 2000-06-26 2002-11-11 Use of Gabapentin analogues for the preparation of preparations for the treatment of sleep disorders

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL152770A IL152770A (en) 2000-06-26 2002-11-11 Use of Gabapentin analogues for the preparation of preparations for the treatment of sleep disorders

Country Status (24)

Country Link
US (1) US7141606B2 (cs)
EP (1) EP1296671B1 (cs)
JP (1) JP3909842B2 (cs)
KR (1) KR100785182B1 (cs)
CN (1) CN1279900C (cs)
AT (1) ATE390133T1 (cs)
AU (2) AU2001264736B2 (cs)
BR (1) BR0111913A (cs)
CA (1) CA2414008C (cs)
CZ (1) CZ20024110A3 (cs)
DE (1) DE60133389T2 (cs)
DK (1) DK1296671T3 (cs)
ES (1) ES2300332T3 (cs)
HK (1) HK1056681A1 (cs)
HU (1) HUP0300833A3 (cs)
IL (2) IL152770A0 (cs)
MX (1) MXPA02010668A (cs)
NZ (1) NZ522480A (cs)
PL (1) PL359872A1 (cs)
PT (1) PT1296671E (cs)
SK (1) SK17922002A3 (cs)
TW (1) TWI298020B (cs)
WO (1) WO2002000209A2 (cs)
ZA (1) ZA200209418B (cs)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL157932A0 (en) 2001-04-19 2004-03-28 Warner Lambert Co Fused bicyclic or tricyclic amino acids
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
AU2002345638A1 (en) 2001-06-11 2002-12-23 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
ES2296956T5 (es) 2001-06-11 2011-07-12 Xenoport, Inc. Profármacos de análogos de gaba, composiciones y sus usos.
AU2002316231A1 (en) 2002-02-19 2003-09-29 Xenoport, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
AU2003222033A1 (en) 2002-03-20 2003-10-08 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
AU2003243180A1 (en) 2002-05-17 2003-12-12 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
WO2004052360A1 (en) 2002-12-11 2004-06-24 Xenoport, Inc. Prodrugs of fused gaba analogs, pharmaceutical compositions and uses thereof
NZ540336A (en) * 2002-12-13 2008-03-28 Warner Lambert Co Gabapentin analogues for fibromyalgia and other related disorders
CA2451267A1 (en) * 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
EP1622603A4 (en) * 2003-03-25 2010-03-24 Kiel Lab Inc GABAPENTINIC PHENOLIC ACID SALTS IN SOLID DOSAGE FORMS AND METHODS OF USE
AU2004272111A1 (en) 2003-09-11 2005-03-24 Xenoport, Inc. Treating and/or preventing urinary incontinence using prodrugs of GABA analogs
CA2538802C (en) 2003-09-17 2015-01-27 Xenoport, Inc. Treating or preventing restless legs syndrome using prodrugs of gaba analogs
BRPI0415288B8 (pt) 2003-10-14 2021-05-25 Xenoport Inc composição farmacêutica compreendendo o ácido 1-{[(a- isobutanoiloxietoxi) carbonil] aminometil}- 1-ciclo- hexano acético cristalino
JP4613031B2 (ja) * 2004-05-06 2011-01-12 エスエス製薬株式会社 催眠剤組成物
JP2005325070A (ja) * 2004-05-14 2005-11-24 Ss Pharmaceut Co Ltd 睡眠改善剤
CA2584338C (en) 2004-11-04 2013-08-06 Xenoport, Inc. Gabapentin prodrug sustained release oral dosage forms
CA2612186A1 (en) 2005-06-23 2007-01-04 Emory University Imaging agents
KR20070070307A (ko) * 2005-08-24 2007-07-04 에스에스 세야쿠 가부시키 가이샤 수면 개선 의약 조성물
AU2007222112A1 (en) * 2006-03-06 2007-09-13 Pfizer Products Inc. Alpha-2-delta ligands for non-restorative sleep
WO2009094577A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
EP2250148B1 (en) 2008-01-25 2016-08-17 XenoPort, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use
TWI380812B (zh) 2008-01-25 2013-01-01 Xenoport Inc （３ｓ）-胺甲基-５-甲基己酸前藥之晶形及使用方法
AU2009302241B2 (en) 2008-10-08 2015-10-29 Xgene Pharmaceutical Inc. GABA conjugates and methods of use thereof
AU2010328186B2 (en) 2009-12-08 2014-12-18 Case Western Reserve University Compounds and methods of treating ocular disorders
US9066853B2 (en) 2013-01-15 2015-06-30 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable fiber
US10130715B2 (en) 2013-01-28 2018-11-20 Hector L. Lopez Methods of improving tolerability, pharmacodynamics, and efficacy of β-alanine and use therefor
EP3466427A4 (en) * 2016-05-26 2020-02-05 Amino Up Chemical Co., Ltd. SLEEP ENHANCEMENT AGENT
AU2019271799B2 (en) 2018-05-14 2023-10-12 Xgene Pharmaceutical Inc. Crystalline forms of 1-(acyloxy)-alkyl carbamate drug conjugates of naproxen and pregabalin

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
US5084479A (en) 1990-01-02 1992-01-28 Warner-Lambert Company Novel methods for treating neurodegenerative diseases
US6197819B1 (en) 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
US5510381A (en) 1995-05-15 1996-04-23 Warner-Lambert Company Method of treatment of mania and bipolar disorder
DE19525598C2 (de) * 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
NZ331142A (en) * 1996-03-14 2001-04-27 Warner Lambert Co Bridged cyclic amino acids as pharmaceutical agents
US6372792B1 (en) * 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
CN1303059C (zh) 1997-10-27 2007-03-07 沃尼尔·朗伯公司 作为药物的环状氨基酸及其衍生物
PL345338A1 (en) * 1998-07-09 2001-12-17 Warner Lambert Co Method for the treatment of insomnia
BR0011236A (pt) * 1999-06-02 2002-03-05 Warner Lambert Co Amino heterociclos úteis como agentes farmacêuticos
HN2000000224A (es) * 1999-10-20 2001-04-11 Warner Lambert Co Aminoacidos biciclicos como agentes farmaceuticos
YU41602A (sh) 1999-12-08 2005-07-19 Warner-Lambert Company Postupak za stereoselektivnu sintezu cikličnih aminokiselina
GB9930083D0 (en) * 1999-12-20 2000-02-09 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
SK17922002A3 (sk) 2003-11-04
TWI298020B (en) 2008-06-21
HUP0300833A3 (en) 2009-08-28
CZ20024110A3 (cs) 2003-10-15
HUP0300833A2 (hu) 2003-08-28
KR100785182B1 (ko) 2007-12-11
DE60133389D1 (de) 2008-05-08
CA2414008A1 (en) 2002-01-03
ATE390133T1 (de) 2008-04-15
DE60133389T2 (de) 2008-06-26
ES2300332T3 (es) 2008-06-16
BR0111913A (pt) 2004-01-06
PL359872A1 (en) 2004-09-06
EP1296671A2 (en) 2003-04-02
HK1056681A1 (en) 2004-02-27
PT1296671E (pt) 2008-05-09
WO2002000209A2 (en) 2002-01-03
KR20030019455A (ko) 2003-03-06
IL152770A (en) 2009-12-24
EP1296671B1 (en) 2008-03-26
MXPA02010668A (es) 2003-03-10
DK1296671T3 (da) 2008-06-16
CN1279900C (zh) 2006-10-18
JP3909842B2 (ja) 2007-04-25
ZA200209418B (en) 2005-03-10
CN1436075A (zh) 2003-08-13
CA2414008C (en) 2011-04-26
US20030212133A1 (en) 2003-11-13
JP2004501189A (ja) 2004-01-15
US7141606B2 (en) 2006-11-28
WO2002000209A3 (en) 2003-01-16
AU2001264736B2 (en) 2006-04-27
NZ522480A (en) 2005-06-24
AU6473601A (en) 2002-01-08

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