IL152701A0 - Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists - Google Patents
Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonistsInfo
- Publication number
- IL152701A0 IL152701A0 IL15270101A IL15270101A IL152701A0 IL 152701 A0 IL152701 A0 IL 152701A0 IL 15270101 A IL15270101 A IL 15270101A IL 15270101 A IL15270101 A IL 15270101A IL 152701 A0 IL152701 A0 IL 152701A0
- Authority
- IL
- Israel
- Prior art keywords
- lactams
- aminoalkyl
- substituted
- receptor antagonists
- muscarinic receptor
- Prior art date
Links
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title 1
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- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20748300P | 2000-05-25 | 2000-05-25 | |
US26757901P | 2001-02-09 | 2001-02-09 | |
PCT/EP2001/005584 WO2001090081A1 (en) | 2000-05-25 | 2001-05-16 | Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
IL152701A0 true IL152701A0 (en) | 2003-06-24 |
Family
ID=26902273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15270101A IL152701A0 (en) | 2000-05-25 | 2001-05-16 | Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists |
Country Status (28)
Country | Link |
---|---|
US (3) | US6667301B2 (xx) |
EP (1) | EP1289965B1 (xx) |
JP (1) | JP4071000B2 (xx) |
KR (1) | KR100544000B1 (xx) |
CN (1) | CN1178922C (xx) |
AR (1) | AR028624A1 (xx) |
AT (1) | ATE307806T1 (xx) |
AU (1) | AU782191B2 (xx) |
BR (1) | BR0111061A (xx) |
CA (1) | CA2409841C (xx) |
CZ (1) | CZ302807B6 (xx) |
DE (1) | DE60114413T2 (xx) |
ES (1) | ES2251517T3 (xx) |
HR (1) | HRP20020904A2 (xx) |
HU (1) | HUP0302010A2 (xx) |
IL (1) | IL152701A0 (xx) |
MA (1) | MA26906A1 (xx) |
MX (1) | MXPA02011418A (xx) |
MY (1) | MY140835A (xx) |
NO (1) | NO20025640L (xx) |
NZ (1) | NZ522411A (xx) |
PE (1) | PE20011325A1 (xx) |
PL (1) | PL204753B1 (xx) |
RU (1) | RU2241702C2 (xx) |
TW (1) | TWI306095B (xx) |
UY (1) | UY26729A1 (xx) |
WO (1) | WO2001090081A1 (xx) |
YU (1) | YU88902A (xx) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1289965B1 (en) * | 2000-05-25 | 2005-10-26 | F. Hoffmann-La Roche Ag | Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists |
US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
KR100958552B1 (ko) * | 2001-06-11 | 2010-05-17 | 제노포트 인코포레이티드 | Gaba 유사체의 프로드러그, 이의 조성물 및 용도 |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
JP4353803B2 (ja) | 2001-12-03 | 2009-10-28 | エフ.ホフマン−ラ ロシュ アーゲー | ムスカリン受容体アンタゴニストとしての4−ピペリジニルアルキルアミン誘導体 |
WO2003048125A1 (en) | 2001-12-03 | 2003-06-12 | F. Hoffmann-La Roche Ag | Aminotetralin derivatives as muscarinic receptor antagonists |
CA2492121A1 (en) | 2002-07-08 | 2004-01-15 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists |
US7517905B2 (en) | 2003-04-09 | 2009-04-14 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
JP2006522787A (ja) | 2003-04-11 | 2006-10-05 | ランバクシー ラボラトリーズ リミテッド | ムスカリン様受容体アンタゴニストとしてのアザビシクロ誘導体 |
CN102429882B (zh) | 2004-11-04 | 2015-03-25 | 什诺波特有限公司 | 加巴喷丁前体药物持续释放口服剂型 |
AU2006265639A1 (en) | 2005-07-01 | 2007-01-11 | Jenrin Discovery | MAO-B inhibitors useful for treating obesity |
RU2008119323A (ru) | 2005-10-19 | 2009-11-27 | Рэнбакси Лабораториз Лимитед (In) | Фармацевтические композиции мускаринового рецептора |
TWI423967B (zh) * | 2008-02-21 | 2014-01-21 | Dainippon Sumitomo Pharma Co | 醯胺衍生物及含有其之醫藥組合物 |
US8008291B2 (en) * | 2008-02-29 | 2011-08-30 | Mimetica Pty Ltd | 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5 receptor antagonists |
JP5503559B2 (ja) * | 2008-02-29 | 2014-05-28 | ミメチカ ピーティーワイ エルティーディー | 3−置換−1,4−ジアゼパン−2−オンメラノコルチン−5受容体アンタゴニスト |
ES2421537T3 (es) * | 2008-05-01 | 2013-09-03 | Vitae Pharmaceuticals Inc | Inhibidores cíclicos de la 11beta-hidroxiesteroide deshidrogenasa 1 |
PL2324018T3 (pl) * | 2008-07-25 | 2014-02-28 | Boehringer Ingelheim Int | Cykliczne inhibitory dehydrogenazy 11 beta-hydroksysteroidowej typu 1 |
CN102112451B (zh) * | 2008-07-28 | 2014-01-22 | 弗·哈夫曼-拉罗切有限公司 | 用作趋化因子受体调节剂的二氮杂环庚烷和哌嗪衍生物 |
US8757092B2 (en) | 2011-03-22 | 2014-06-24 | Eco-Composites Llc | Animal bedding and associated method for preparing the same |
US9737047B2 (en) | 2011-03-22 | 2017-08-22 | Ccd Holdings Llc | Method for the treatment, control, minimization, and prevention of bovine mastitis |
PT3153511T (pt) * | 2014-06-06 | 2019-06-28 | Astellas Pharma Inc | Derivado de 2-acilaminotiazole para utilização na prevenção ou tratamento de doenças da bexiga/trato urinário |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
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US3054794A (en) | 1958-01-17 | 1962-09-18 | Us Vitamin Pharm Corp | Process for preparing 3-(aminoalkyl)-oxazolidine-2, 4-diones |
US3354178A (en) | 1965-04-09 | 1967-11-21 | Sterling Drug Inc | Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides |
US4065471A (en) | 1965-04-09 | 1977-12-27 | Sterling Drug Inc. | N-(4-Amino-2-butynyl)imides |
AT345806B (de) | 1975-03-06 | 1978-10-10 | Thomae Gmbh Dr K | Verfahren zur herstellung neuer substituierter arylalkylamine und deren salze |
DD123741A5 (xx) | 1975-03-06 | 1977-01-12 | ||
US4087541A (en) | 1975-03-06 | 1978-05-02 | Boehringer Ingelheim Gmbh | 2-(Aralkylaminoalkyl)phthalimidines |
US4083407A (en) * | 1977-02-07 | 1978-04-11 | The Dow Chemical Company | Spacer composition and method of use |
US4490369A (en) | 1981-05-19 | 1984-12-25 | Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung | Benzazepine derivatives, their pharmaceutical compositions and method of use |
US4729994A (en) | 1986-08-20 | 1988-03-08 | Mcneilab, Inc. | Benzothiazepine vasodilators having aralkyl substitution |
DE3631013A1 (de) | 1986-09-12 | 1988-03-24 | Thomae Gmbh Dr K | Neue naphthylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
US5177089A (en) | 1988-06-01 | 1993-01-05 | Eisai Co., Ltd. | Butenoic or propenoic acid derivative |
FI892362A (fi) | 1988-06-01 | 1989-12-02 | Eisai Co Ltd | Buten- eller propensyraderivat. |
US5998452A (en) | 1993-06-23 | 1999-12-07 | Chugai Seiyaku Kabushiki Kaisha | Benzene derivatives, compositions and methods for treating ischemic diseases |
SE9303274D0 (sv) | 1993-10-07 | 1993-10-07 | Astra Ab | Novel phenylethyl and phenylproplamines |
US6319920B1 (en) * | 1998-02-27 | 2001-11-20 | Syntex (U.S.A.) Llc | 2-arylethyl-(piperidin-4-ylmethyl)amine derivatives |
EP1289965B1 (en) * | 2000-05-25 | 2005-10-26 | F. Hoffmann-La Roche Ag | Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists |
-
2001
- 2001-05-16 EP EP01980030A patent/EP1289965B1/en not_active Expired - Lifetime
- 2001-05-16 KR KR1020027015885A patent/KR100544000B1/ko not_active IP Right Cessation
- 2001-05-16 IL IL15270101A patent/IL152701A0/xx unknown
- 2001-05-16 CN CNB018100430A patent/CN1178922C/zh not_active Expired - Fee Related
- 2001-05-16 CA CA002409841A patent/CA2409841C/en not_active Expired - Fee Related
- 2001-05-16 ES ES01980030T patent/ES2251517T3/es not_active Expired - Lifetime
- 2001-05-16 MX MXPA02011418A patent/MXPA02011418A/es active IP Right Grant
- 2001-05-16 DE DE60114413T patent/DE60114413T2/de not_active Expired - Lifetime
- 2001-05-16 PL PL361282A patent/PL204753B1/pl unknown
- 2001-05-16 JP JP2001586270A patent/JP4071000B2/ja not_active Expired - Fee Related
- 2001-05-16 NZ NZ522411A patent/NZ522411A/en unknown
- 2001-05-16 CZ CZ20024200A patent/CZ302807B6/cs not_active IP Right Cessation
- 2001-05-16 YU YU88902A patent/YU88902A/sh unknown
- 2001-05-16 HU HU0302010A patent/HUP0302010A2/hu unknown
- 2001-05-16 WO PCT/EP2001/005584 patent/WO2001090081A1/en active IP Right Grant
- 2001-05-16 AU AU10122/02A patent/AU782191B2/en not_active Ceased
- 2001-05-16 BR BR0111061-6A patent/BR0111061A/pt active Search and Examination
- 2001-05-16 AT AT01980030T patent/ATE307806T1/de active
- 2001-05-16 RU RU2002133208/04A patent/RU2241702C2/ru not_active IP Right Cessation
- 2001-05-21 PE PE2001000457A patent/PE20011325A1/es not_active Application Discontinuation
- 2001-05-22 US US09/862,286 patent/US6667301B2/en not_active Expired - Lifetime
- 2001-05-23 MY MYPI20012428A patent/MY140835A/en unknown
- 2001-05-24 UY UY26729A patent/UY26729A1/es not_active Application Discontinuation
- 2001-05-24 AR ARP010102491A patent/AR028624A1/es not_active Application Discontinuation
- 2001-05-25 TW TW090112671A patent/TWI306095B/zh not_active IP Right Cessation
-
2002
- 2002-11-14 HR HRP20020904 patent/HRP20020904A2/hr not_active Application Discontinuation
- 2002-11-22 NO NO20025640A patent/NO20025640L/no not_active Application Discontinuation
- 2002-11-22 MA MA26922A patent/MA26906A1/fr unknown
-
2003
- 2003-10-14 US US10/685,124 patent/US7094778B2/en not_active Expired - Fee Related
-
2006
- 2006-08-22 US US11/508,581 patent/US7361648B2/en not_active Expired - Fee Related
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