IL149585A0 - Process for the preparation of arylethanolamine derivatives having anti-obesity and anti-diabetic properties - Google Patents
Process for the preparation of arylethanolamine derivatives having anti-obesity and anti-diabetic propertiesInfo
- Publication number
- IL149585A0 IL149585A0 IL14958500A IL14958500A IL149585A0 IL 149585 A0 IL149585 A0 IL 149585A0 IL 14958500 A IL14958500 A IL 14958500A IL 14958500 A IL14958500 A IL 14958500A IL 149585 A0 IL149585 A0 IL 149585A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- obesity
- diabetic properties
- arylethanolamine derivatives
- arylethanolamine
- Prior art date
Links
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 230000003579 anti-obesity Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9929297.1A GB9929297D0 (en) | 1999-12-11 | 1999-12-11 | Process |
| PCT/GB2000/004697 WO2001042195A1 (en) | 1999-12-11 | 2000-12-08 | Process for the preparation of arylethanolamine derivatives having an anti-obesity and anti-diabetic properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL149585A0 true IL149585A0 (en) | 2002-11-10 |
Family
ID=10866125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14958500A IL149585A0 (en) | 1999-12-11 | 2000-12-08 | Process for the preparation of arylethanolamine derivatives having anti-obesity and anti-diabetic properties |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6548523B2 (cs) |
| EP (1) | EP1235788B1 (cs) |
| JP (1) | JP4903964B2 (cs) |
| KR (1) | KR100683614B1 (cs) |
| CN (1) | CN1224609C (cs) |
| AT (1) | ATE292110T1 (cs) |
| AU (1) | AU769387B2 (cs) |
| BR (1) | BRPI0016187B1 (cs) |
| CA (1) | CA2394117C (cs) |
| CZ (1) | CZ303143B6 (cs) |
| DE (1) | DE60019157T2 (cs) |
| ES (1) | ES2236020T3 (cs) |
| GB (1) | GB9929297D0 (cs) |
| HK (1) | HK1045988B (cs) |
| HU (1) | HU229043B1 (cs) |
| IL (1) | IL149585A0 (cs) |
| NO (1) | NO323239B1 (cs) |
| NZ (1) | NZ518795A (cs) |
| PL (1) | PL200540B1 (cs) |
| PT (1) | PT1235788E (cs) |
| TR (1) | TR200201528T2 (cs) |
| WO (1) | WO2001042195A1 (cs) |
| ZA (1) | ZA200204585B (cs) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10230147A1 (de) * | 2001-10-09 | 2004-01-15 | Profos Ag | Verfahren zur unspezifischen Anreicherung von Bakterienzellen |
| US7158049B2 (en) * | 2003-03-24 | 2007-01-02 | Schlumberger Technology Corporation | Wireless communication circuit |
| US8213085B2 (en) * | 2008-01-18 | 2012-07-03 | Visera Technologies Company Limited | Image sensor device with high photosensitivity |
| WO2010118291A2 (en) | 2009-04-10 | 2010-10-14 | Auspex Pharmaceuticals, Inc. | Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor |
| NZ607485A (en) | 2010-08-03 | 2015-04-24 | Altherx Inc | Combinations of beta - 3 adrenergic receptor agonists and muscarinic receptor antagonists for treating overactive bladder |
| US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
| HK1204966A1 (en) | 2012-02-09 | 2015-12-11 | Velicept Therapeutics, Inc. | Combination of muscarinic receptor antagonists and beta- 3 adrenoceptor agonists for treating overactive bladder |
| US9956194B2 (en) | 2014-12-03 | 2018-05-01 | Velicept Therapeutics, Inc. | Compositions and methods of using modified release solabegron for lower urinary tract symptoms |
| PL3365321T3 (pl) | 2015-10-23 | 2024-03-25 | B3Ar Therapeutics, Inc. | Jon obojnaczy solabegronu i jego zastosowania |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1551260A (en) | 1976-02-09 | 1979-08-30 | Allen & Hanburys Ltd | Phenylethanolamine derivatives |
| JP2577222B2 (ja) * | 1987-04-10 | 1997-01-29 | 興和株式会社 | 新規な置換アニリド誘導体 |
| NO179246C (no) * | 1991-11-20 | 1996-09-04 | Sankyo Co | Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav |
| GB9525121D0 (en) | 1995-12-08 | 1996-02-07 | Glaxo Group Ltd | Chemical compounds |
| SK16282000A3 (sk) * | 1998-05-01 | 2001-05-10 | Abbott Laboratories | Substituované beta-aminokyselinové inhibítory metionínaminopeptidázy-2 |
| GB9812709D0 (en) * | 1998-06-13 | 1998-08-12 | Glaxo Group Ltd | Chemical compounds |
-
1999
- 1999-12-11 GB GBGB9929297.1A patent/GB9929297D0/en not_active Ceased
-
2000
- 2000-12-08 ES ES00985495T patent/ES2236020T3/es not_active Expired - Lifetime
- 2000-12-08 BR BRPI0016187A patent/BRPI0016187B1/pt not_active IP Right Cessation
- 2000-12-08 HK HK02107499.9A patent/HK1045988B/en not_active IP Right Cessation
- 2000-12-08 AT AT00985495T patent/ATE292110T1/de active
- 2000-12-08 CN CNB008170177A patent/CN1224609C/zh not_active Expired - Fee Related
- 2000-12-08 IL IL14958500A patent/IL149585A0/xx not_active IP Right Cessation
- 2000-12-08 PT PT00985495T patent/PT1235788E/pt unknown
- 2000-12-08 JP JP2001543497A patent/JP4903964B2/ja not_active Expired - Fee Related
- 2000-12-08 KR KR1020027007383A patent/KR100683614B1/ko not_active Expired - Fee Related
- 2000-12-08 US US10/148,841 patent/US6548523B2/en not_active Expired - Lifetime
- 2000-12-08 PL PL356483A patent/PL200540B1/pl unknown
- 2000-12-08 TR TR2002/01528T patent/TR200201528T2/xx unknown
- 2000-12-08 CA CA2394117A patent/CA2394117C/en not_active Expired - Fee Related
- 2000-12-08 DE DE60019157T patent/DE60019157T2/de not_active Expired - Lifetime
- 2000-12-08 HU HU0203640A patent/HU229043B1/hu not_active IP Right Cessation
- 2000-12-08 CZ CZ20022017A patent/CZ303143B6/cs not_active IP Right Cessation
- 2000-12-08 AU AU21911/01A patent/AU769387B2/en not_active Ceased
- 2000-12-08 NZ NZ518795A patent/NZ518795A/en unknown
- 2000-12-08 WO PCT/GB2000/004697 patent/WO2001042195A1/en active IP Right Grant
- 2000-12-08 EP EP00985495A patent/EP1235788B1/en not_active Expired - Lifetime
-
2002
- 2002-06-07 ZA ZA200204585A patent/ZA200204585B/xx unknown
- 2002-06-10 NO NO20022758A patent/NO323239B1/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |