IL146789A0 - Amorphous nitric esters and their pharmaceutical compositions - Google Patents

Amorphous nitric esters and their pharmaceutical compositions

Info

Publication number
IL146789A0
IL146789A0 IL14678900A IL14678900A IL146789A0 IL 146789 A0 IL146789 A0 IL 146789A0 IL 14678900 A IL14678900 A IL 14678900A IL 14678900 A IL14678900 A IL 14678900A IL 146789 A0 IL146789 A0 IL 146789A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
nitric esters
amorphous
amorphous nitric
esters
Prior art date
Application number
IL14678900A
Other languages
English (en)
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of IL146789A0 publication Critical patent/IL146789A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL14678900A 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions IL146789A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche
PCT/EP2000/005723 WO2001000563A1 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions

Publications (1)

Publication Number Publication Date
IL146789A0 true IL146789A0 (en) 2002-07-25

Family

ID=11383219

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14678900A IL146789A0 (en) 1999-06-24 2000-06-21 Amorphous nitric esters and their pharmaceutical compositions

Country Status (23)

Country Link
US (1) US6753442B1 (es)
EP (1) EP1187803B1 (es)
JP (1) JP2003503380A (es)
KR (1) KR100672001B1 (es)
CN (1) CN1187312C (es)
AT (1) ATE302746T1 (es)
AU (1) AU781479B2 (es)
BR (1) BR0011831A (es)
CA (1) CA2377132A1 (es)
DE (1) DE60022188T2 (es)
DK (1) DK1187803T3 (es)
ES (1) ES2246878T3 (es)
HU (1) HUP0201721A3 (es)
IL (1) IL146789A0 (es)
IT (1) IT1312115B1 (es)
MX (1) MXPA01013273A (es)
NO (1) NO321523B1 (es)
NZ (1) NZ515757A (es)
PL (1) PL195557B1 (es)
RU (1) RU2248963C2 (es)
TR (1) TR200103624T2 (es)
WO (1) WO2001000563A1 (es)
ZA (1) ZA200109862B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
JP4092203B2 (ja) 2000-12-21 2008-05-28 ニトロメッド，インク． 新規のシクロオキシゲナーゼ２選択的阻害剤としての置換アリール化合物、組成物、および使用方法
EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
EP1539134A4 (en) 2002-06-11 2007-04-11 Nitromed Inc SELECTIVE INHIBITORS OF CYCLOOXIGENASE-2 NITROSIS AND / OR NITROSYLES, COMPOSITIONS AND METHODS OF USE
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
CA2493156A1 (en) 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
MXPA06000795A (es) 2003-07-22 2006-08-23 Arena Pharm Inc Derivados de diaril y arilheteroaril urea como moduladores del receptor 5-ht2a de serotonina utiles para la profilaxis y tratamiento de desordenes relacionados con el mismo.
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
ES2421237T7 (es) 2007-08-15 2013-09-30 Arena Pharmaceuticals, Inc. Derivados de imidazo[1,2-a]piridin como moduladores del receptor serotoninérgico 5ht2a en el tratamiento de trastornos relacionados con el mismo
BRPI0818575A2 (pt) * 2007-10-17 2014-10-07 Todd F Ovokaitys Processo para a modificação do estado sólido de um composto e composições co-amorfas produzidas com o mesmo
CA2702909C (en) * 2007-10-17 2016-05-10 Todd F. Ovokaitys Room temperature stable non-crystalline aspirin
ES2324007A1 (es) * 2007-10-25 2009-07-28 Ferrer Internacional, S.A. Una forma amorfa de un compuesto antiinflamatorio.
WO2009123714A2 (en) 2008-04-02 2009-10-08 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
LT2364142T (lt) * 2008-10-28 2018-06-25 Arena Pharmaceuticals, Inc. 5-ht2a serotonino receptoriaus moduliatoriaus kompozicijos, naudotinos su juo susijusių sutrikimų gydymui
WO2010062321A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
WO2010053532A2 (en) 2008-11-04 2010-05-14 Dsm Ip Assets B.V. D 1413 ht radiation curable coatings for optical fiber
US10202598B2 (en) 2014-05-30 2019-02-12 Todd Frank Ovokaitys Methods and systems for generation, use, and delivery of activated stem cells
WO2015187974A1 (en) 2014-06-06 2015-12-10 Ovokaitys Todd Frank Methods and compositions for increasing the bioactivity of nutrients
US10384985B2 (en) 2014-06-06 2019-08-20 B.K. Consultants, Inc. Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants
EP4119141A1 (en) 2015-06-12 2023-01-18 Axovant Sciences GmbH Nelotanserin for the prophylaxis and treatment of rem sleep behavior disorder
CA2992518A1 (en) 2015-07-15 2017-01-19 Axovant Sciences Gmbh Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
IT1256345B (it) * 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
JP4043046B2 (ja) * 1994-05-10 2008-02-06 ニコックス エス エイ 消炎、鎮痛および抗血栓活性を有するニトロ化合物およびそれらの組成物
IT1276071B1 (it) 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
KR19990001564A (ko) 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
ITMI991402A1 (it) 2000-12-24
HUP0201721A3 (en) 2003-08-28
ES2246878T3 (es) 2006-03-01
EP1187803B1 (en) 2005-08-24
ATE302746T1 (de) 2005-09-15
PL352529A1 (en) 2003-08-25
AU781479B2 (en) 2005-05-26
CN1356975A (zh) 2002-07-03
NO20016232L (no) 2001-12-19
US6753442B1 (en) 2004-06-22
BR0011831A (pt) 2002-03-19
HUP0201721A2 (en) 2002-10-28
PL195557B1 (pl) 2007-10-31
NZ515757A (en) 2004-02-27
DK1187803T3 (da) 2005-11-28
TR200103624T2 (tr) 2002-04-22
NO321523B1 (no) 2006-05-15
CN1187312C (zh) 2005-02-02
EP1187803A1 (en) 2002-03-20
IT1312115B1 (it) 2002-04-04
JP2003503380A (ja) 2003-01-28
MXPA01013273A (es) 2003-07-14
NO20016232D0 (no) 2001-12-19
CA2377132A1 (en) 2001-01-04
ITMI991402A0 (it) 1999-06-24
KR20020008220A (ko) 2002-01-29
DE60022188D1 (de) 2005-09-29
ZA200109862B (en) 2003-05-28
AU6264400A (en) 2001-01-31
RU2248963C2 (ru) 2005-03-27
WO2001000563A1 (en) 2001-01-04
DE60022188T2 (de) 2006-06-08
KR100672001B1 (ko) 2007-01-19

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees