IL142695A0 - Crystal modification b of 8-cyano-1-cyclopropyl-7-(1s,6s,-2, 8-diazabicyclo [4.3.0] nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid - Google Patents

Crystal modification b of 8-cyano-1-cyclopropyl-7-(1s,6s,-2, 8-diazabicyclo [4.3.0] nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid

Info

Publication number
IL142695A0
IL142695A0 IL14269599A IL14269599A IL142695A0 IL 142695 A0 IL142695 A0 IL 142695A0 IL 14269599 A IL14269599 A IL 14269599A IL 14269599 A IL14269599 A IL 14269599A IL 142695 A0 IL142695 A0 IL 142695A0
Authority
IL
Israel
Prior art keywords
nonan
diazabicyclo
cyclopropyl
dihydro
oxo
Prior art date
Application number
IL14269599A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL142695A0 publication Critical patent/IL142695A0/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
IL14269599A 1998-11-25 1999-11-15 Crystal modification b of 8-cyano-1-cyclopropyl-7-(1s,6s,-2, 8-diazabicyclo [4.3.0] nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid IL142695A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19854355A DE19854355A1 (de) 1998-11-25 1998-11-25 Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
PCT/EP1999/008776 WO2000031076A1 (de) 1998-11-25 1999-11-15 Kristallmodifikation b von 8-cyan- 1-cyclopropyl -7-(1s,6s-2, 8-diazabicyclo -[4.3.0]nonan -8-yl)-6- fluor-1, 4-dihydro- 4-oxo-3- chinolincarbonsaure

Publications (1)

Publication Number Publication Date
IL142695A0 true IL142695A0 (en) 2002-03-10

Family

ID=7888959

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14269599A IL142695A0 (en) 1998-11-25 1999-11-15 Crystal modification b of 8-cyano-1-cyclopropyl-7-(1s,6s,-2, 8-diazabicyclo [4.3.0] nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid
IL142695A IL142695A (en) 1998-11-25 2001-04-19 Crystalline form B of carboxylic acid 8 - cyano - 1 - cyclopropyl - 7 - (1S, S6 - 2, 8 - diazabicyclo [0.3.4] nonan - 8 - ile) - 6 - fluorine 4, 1 - dehydrogen - 4 - oxo Quinolinkerboxylic acid and pharmaceutical preparations containing it

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL142695A IL142695A (en) 1998-11-25 2001-04-19 Crystalline form B of carboxylic acid 8 - cyano - 1 - cyclopropyl - 7 - (1S, S6 - 2, 8 - diazabicyclo [0.3.4] nonan - 8 - ile) - 6 - fluorine 4, 1 - dehydrogen - 4 - oxo Quinolinkerboxylic acid and pharmaceutical preparations containing it

Country Status (29)

Country Link
US (1) US6664268B1 (xx)
EP (1) EP1133497B1 (xx)
JP (2) JP5127094B2 (xx)
KR (1) KR100740950B1 (xx)
CN (1) CN1150193C (xx)
AR (1) AR028467A1 (xx)
AT (1) ATE289606T1 (xx)
AU (1) AU767890B2 (xx)
BR (1) BRPI9915682B8 (xx)
CA (1) CA2351707C (xx)
CZ (1) CZ300012B6 (xx)
DE (2) DE19854355A1 (xx)
DK (1) DK1133497T3 (xx)
ES (1) ES2237186T3 (xx)
HK (1) HK1042705B (xx)
HU (1) HU229071B1 (xx)
IL (2) IL142695A0 (xx)
NO (1) NO318065B1 (xx)
NZ (1) NZ511862A (xx)
PL (1) PL196078B1 (xx)
PT (1) PT1133497E (xx)
RU (1) RU2248355C2 (xx)
SK (1) SK285554B6 (xx)
TR (1) TR200101444T2 (xx)
TW (1) TWI245767B (xx)
UA (1) UA67873C2 (xx)
UY (1) UY25818A (xx)
WO (1) WO2000031076A1 (xx)
ZA (1) ZA200103187B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin
DE102007026550A1 (de) 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
WO2018146194A1 (en) 2017-02-13 2018-08-16 Bayer Animal Health Gmbh Liquid composition containing pradofloxacin

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA25898A1 (uk) * 1987-02-02 1999-02-26 Пфайзер Інк. Спосіб одержаhhя кристалічhої hатрієвої солі 5-хлор-3-(2-теhоїл)-2-оксііhдол-1-карбоксаміду
JP2676521B2 (ja) * 1988-03-22 1997-11-17 北陸製薬株式会社 キノロンカルボン酸化合物ｉ型結晶の製造法
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
JP2832848B2 (ja) * 1989-10-21 1998-12-09 株式会社林原生物化学研究所 結晶２―Ｏ―α―Ｄ―グルコピラノシル―Ｌ―アスコルビン酸とその製造方法並びに用途
BR9509688A (pt) * 1994-11-18 1997-09-30 Upjohn Co Composto e composição farmacêutica
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
DK0882049T3 (da) * 1996-02-23 2003-03-03 Bayer Ag Eventuelt substituerede 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyrer og deres derivater
DE19649681A1 (de) * 1996-11-29 1998-06-04 Basf Ag Verfahren zur Herstellung eines kristallinen Feststoffes aus Glycin-N,N-diessigsäure-Derivaten mit hinreichend geringer Hygroskopizität
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure

Also Published As

Publication number Publication date
TWI245767B (en) 2005-12-21
ZA200103187B (en) 2002-06-26
UY25818A (es) 2016-06-30
BR9915682A (pt) 2001-08-14
PT1133497E (pt) 2005-07-29
WO2000031076A1 (de) 2000-06-02
SK6832001A3 (en) 2001-12-03
CZ300012B6 (cs) 2009-01-14
EP1133497A1 (de) 2001-09-19
NO20012461L (no) 2001-05-18
TR200101444T2 (tr) 2002-01-21
CZ20011857A3 (cs) 2001-09-12
CA2351707C (en) 2011-02-01
IL142695A (en) 2006-04-10
ATE289606T1 (de) 2005-03-15
RU2248355C2 (ru) 2005-03-20
EP1133497B1 (de) 2005-02-23
US6664268B1 (en) 2003-12-16
KR100740950B1 (ko) 2007-07-19
NO318065B1 (no) 2005-01-31
UA67873C2 (uk) 2004-07-15
HK1042705B (zh) 2005-03-11
PL196078B1 (pl) 2007-12-31
DE59911666D1 (de) 2005-03-31
JP2002530407A (ja) 2002-09-17
JP2012236841A (ja) 2012-12-06
KR20010080927A (ko) 2001-08-25
HK1042705A1 (en) 2002-08-23
HU229071B1 (en) 2013-07-29
CN1150193C (zh) 2004-05-19
DK1133497T3 (da) 2005-05-17
SK285554B6 (sk) 2007-03-01
JP5127094B2 (ja) 2013-01-23
AU1651700A (en) 2000-06-13
NZ511862A (en) 2003-08-29
BRPI9915682B1 (pt) 2017-02-21
HUP0104713A3 (en) 2002-12-28
DE19854355A1 (de) 2000-05-31
AR028467A1 (es) 2003-05-14
CN1328556A (zh) 2001-12-26
PL347785A1 (en) 2002-04-22
HUP0104713A2 (hu) 2002-04-29
NO20012461D0 (no) 2001-05-18
BRPI9915682B8 (pt) 2021-05-25
CA2351707A1 (en) 2000-06-02
ES2237186T3 (es) 2005-07-16
AU767890B2 (en) 2003-11-27

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