IL142302A - Method and device for preparing a dental implant by immersion in mesenchymal cell culture - Google Patents
Method and device for preparing a dental implant by immersion in mesenchymal cell cultureInfo
- Publication number
- IL142302A IL142302A IL14230299A IL14230299A IL142302A IL 142302 A IL142302 A IL 142302A IL 14230299 A IL14230299 A IL 14230299A IL 14230299 A IL14230299 A IL 14230299A IL 142302 A IL142302 A IL 142302A
- Authority
- IL
- Israel
- Prior art keywords
- implant
- root portion
- preparing
- dental implant
- immersion
- Prior art date
Links
- 239000004053 dental implant Substances 0.000 title abstract 2
- 238000004113 cell culture Methods 0.000 title 1
- 238000007654 immersion Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000007943 implant Substances 0.000 abstract 3
- 210000000250 cementoblast Anatomy 0.000 abstract 2
- 230000004069 differentiation Effects 0.000 abstract 2
- 239000000560 biocompatible material Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000002950 fibroblast Anatomy 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000002379 periodontal ligament Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3865—Dental/periodontal tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/10—Petri dish
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/38—Caps; Covers; Plugs; Pouring means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/14—Rotation or movement of the cells support, e.g. rotated hollow fibers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
- A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Ceramic Engineering (AREA)
- Urology & Nephrology (AREA)
- Dentistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Developmental Biology & Embryology (AREA)
- Vascular Medicine (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9812831A FR2784284B1 (fr) | 1998-10-13 | 1998-10-13 | Procede de preparation d'un implant dentaire par immersion dans une culture de cellules mesenchymateuses, dispositif de culture de cellules pour la preparation dudit implant et implant obtenu |
PCT/FR1999/002462 WO2000021456A1 (fr) | 1998-10-13 | 1999-10-12 | Procede et dispositif de preparation d'un implant dentaire par immersion dans une culture de cellules mesenchymateuses |
Publications (2)
Publication Number | Publication Date |
---|---|
IL142302A0 IL142302A0 (en) | 2002-03-10 |
IL142302A true IL142302A (en) | 2005-06-19 |
Family
ID=9531511
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14230299A IL142302A (en) | 1998-10-13 | 1999-10-12 | Method and device for preparing a dental implant by immersion in mesenchymal cell culture |
Country Status (18)
Country | Link |
---|---|
US (1) | US6589525B2 (xx) |
EP (1) | EP1121064B1 (xx) |
JP (1) | JP4088039B2 (xx) |
KR (1) | KR100602858B1 (xx) |
CN (1) | CN1200654C (xx) |
AT (1) | ATE274862T1 (xx) |
AU (1) | AU757566B2 (xx) |
BR (1) | BR9914448A (xx) |
CA (1) | CA2346555C (xx) |
DE (1) | DE69919883T2 (xx) |
DK (1) | DK1121064T3 (xx) |
ES (1) | ES2229769T3 (xx) |
FR (1) | FR2784284B1 (xx) |
IL (1) | IL142302A (xx) |
PL (1) | PL192841B1 (xx) |
PT (1) | PT1121064E (xx) |
TW (1) | TW425279B (xx) |
WO (1) | WO2000021456A1 (xx) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2179731B1 (es) * | 2000-04-14 | 2004-04-16 | Alberto Arruga Artal | Implante dental y metodo operativo de implantacion. |
FR2819395B1 (fr) * | 2001-01-12 | 2003-08-15 | Natural Implant Sa | Implant dentaire transitoire de preparation d'une alveole |
FR2821853B1 (fr) * | 2001-03-09 | 2003-05-16 | Natural Implant Sa | Bioreacteur pour tissu cultive en couche mince et utilisations |
JPWO2003101502A1 (ja) * | 2002-05-31 | 2005-10-27 | 上田 実 | 歯胚の再生方法および再生歯胚 |
WO2003101503A1 (fr) * | 2002-05-31 | 2003-12-11 | Hitachi Medical Corporation | Procede de regeneration d'un germe dentaire et germe dentaire regenere |
KR100644296B1 (ko) * | 2004-07-24 | 2006-11-10 | 정필훈 | 생체 공학적 턱뼈 및 치아 재건 방법 |
JP4723937B2 (ja) * | 2005-07-13 | 2011-07-13 | 株式会社カネカ | 細胞の播種方法 |
US20100093080A1 (en) * | 2005-07-29 | 2010-04-15 | Matsumoto Dental University | Tooth Regeneration Method |
US7708557B2 (en) * | 2006-10-16 | 2010-05-04 | Natural Dental Implants Ag | Customized dental prosthesis for periodontal- or osseointegration, and related systems and methods |
US9539062B2 (en) | 2006-10-16 | 2017-01-10 | Natural Dental Implants, Ag | Methods of designing and manufacturing customized dental prosthesis for periodontal or osseointegration and related systems |
US8454362B2 (en) * | 2006-10-16 | 2013-06-04 | Natural Dental Implants Ag | Customized dental prosthesis for periodontal- or osseointegration, and related systems and methods |
US10426578B2 (en) * | 2006-10-16 | 2019-10-01 | Natural Dental Implants, Ag | Customized dental prosthesis for periodontal or osseointegration and related systems |
US8602780B2 (en) * | 2006-10-16 | 2013-12-10 | Natural Dental Implants, Ag | Customized dental prosthesis for periodontal or osseointegration and related systems and methods |
US9801697B2 (en) * | 2011-03-18 | 2017-10-31 | Natural Dental Implants Ag | Integrated support device for providing temporary primary stability to dental implants and prosthesis, and related methods |
WO2008067488A2 (en) * | 2006-11-29 | 2008-06-05 | University Of Southern California | Mesenchymal stem cell-mediated functional tooth regeneration |
EP2200622B2 (en) * | 2007-09-19 | 2015-07-29 | Pluristem Ltd. | Adherent cells from adipose or placenta tissues and use thereof in therapy |
WO2010021162A1 (ja) * | 2008-08-19 | 2010-02-25 | 国立大学法人大阪大学 | 骨組織再生用の細胞製剤 |
DE102008049014A1 (de) * | 2008-09-25 | 2010-04-22 | Bagambisa, Frank, Dr. | Dentalimplantat zur Implantation in einen menschlichen oder tierischen Kieferknochen und Verfahren zu seiner Herstellung |
WO2011114218A2 (en) * | 2010-03-16 | 2011-09-22 | Bertoni Hernan Gabriel | Endograft with cultured stem cells |
US9606035B2 (en) | 2011-12-21 | 2017-03-28 | Ta Instruments-Waters Llc | System for mechanical stimulation and characterization of biologic samples |
US10022205B2 (en) * | 2012-02-01 | 2018-07-17 | Organ Technologies, Inc. | Dental implant and method for producing same |
US20160193387A1 (en) * | 2012-12-26 | 2016-07-07 | Quarrymen Corporation | Sophisticated Implant Material |
WO2015106247A1 (en) | 2014-01-13 | 2015-07-16 | Westover Brock B | Endosseous dental implant assembly |
JP6338214B2 (ja) * | 2014-03-28 | 2018-06-06 | 国立研究開発法人国立長寿医療研究センター | インプラント体 |
GB2555901B (en) * | 2016-08-26 | 2019-11-13 | Tran Scell Biologics Private Ltd | Method of preparation of a novel stem cell-biocomplex for clinical implantation in periodontal space |
RU2649452C1 (ru) * | 2017-06-07 | 2018-04-03 | Дмитрий Андреевич Журавлёв | Способ имплантации искусственного зуба |
CN111484936B (zh) * | 2020-05-21 | 2021-04-02 | 吉林大学中日联谊医院 | 一种结直肠癌实体瘤原代细胞的培养装置及培养方法 |
CN117947138B (zh) * | 2024-03-27 | 2024-06-21 | 佳木斯大学 | 一种口腔材料体外细胞毒性测试方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4872840A (en) * | 1987-07-15 | 1989-10-10 | Team Incorporated | Dental implant and method |
JPH01299563A (ja) * | 1988-05-28 | 1989-12-04 | Moritsugu Ootori | インプラント材のポーラス部封孔処理方法 |
DE4040872C3 (de) | 1990-12-20 | 2000-08-24 | Klaus Ursus Schendel | Implantat für den Dentalbereich |
DE4222296A1 (de) | 1990-12-20 | 1993-12-23 | Klaus Ursus Dr Dr Schendel | Implantat für den Dentalberiech und Verfahren zu seiner Herstellung |
JP3471967B2 (ja) * | 1995-03-28 | 2003-12-02 | カネボウ株式会社 | ハイブリッド型人工歯根 |
AU3214797A (en) * | 1996-05-28 | 1998-01-05 | Regents Of The University Of Michigan, The | Engineering oral tissues |
-
1998
- 1998-10-13 FR FR9812831A patent/FR2784284B1/fr not_active Expired - Fee Related
-
1999
- 1999-10-12 AT AT99947554T patent/ATE274862T1/de not_active IP Right Cessation
- 1999-10-12 DE DE69919883T patent/DE69919883T2/de not_active Expired - Fee Related
- 1999-10-12 EP EP99947554A patent/EP1121064B1/fr not_active Expired - Lifetime
- 1999-10-12 PL PL347108A patent/PL192841B1/pl not_active IP Right Cessation
- 1999-10-12 PT PT99947554T patent/PT1121064E/pt unknown
- 1999-10-12 ES ES99947554T patent/ES2229769T3/es not_active Expired - Lifetime
- 1999-10-12 JP JP2000575438A patent/JP4088039B2/ja not_active Expired - Fee Related
- 1999-10-12 DK DK99947554T patent/DK1121064T3/da active
- 1999-10-12 WO PCT/FR1999/002462 patent/WO2000021456A1/fr active IP Right Grant
- 1999-10-12 AU AU60956/99A patent/AU757566B2/en not_active Ceased
- 1999-10-12 CA CA002346555A patent/CA2346555C/fr not_active Expired - Fee Related
- 1999-10-12 CN CNB998121185A patent/CN1200654C/zh not_active Expired - Fee Related
- 1999-10-12 KR KR1020017004612A patent/KR100602858B1/ko not_active IP Right Cessation
- 1999-10-12 BR BR9914448-4A patent/BR9914448A/pt not_active IP Right Cessation
- 1999-10-12 IL IL14230299A patent/IL142302A/xx not_active IP Right Cessation
-
2000
- 2000-04-13 TW TW089106889A patent/TW425279B/zh not_active IP Right Cessation
-
2001
- 2001-04-12 US US09/833,002 patent/US6589525B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU6095699A (en) | 2000-05-01 |
US6589525B2 (en) | 2003-07-08 |
JP2002527139A (ja) | 2002-08-27 |
US20010055745A1 (en) | 2001-12-27 |
EP1121064A1 (fr) | 2001-08-08 |
KR100602858B1 (ko) | 2006-07-20 |
IL142302A0 (en) | 2002-03-10 |
CN1323181A (zh) | 2001-11-21 |
ATE274862T1 (de) | 2004-09-15 |
CA2346555A1 (fr) | 2000-04-20 |
DK1121064T3 (da) | 2005-01-10 |
AU757566B2 (en) | 2003-02-27 |
EP1121064B1 (fr) | 2004-09-01 |
PT1121064E (pt) | 2005-01-31 |
FR2784284A1 (fr) | 2000-04-14 |
PL192841B1 (pl) | 2006-12-29 |
CA2346555C (fr) | 2007-12-04 |
WO2000021456A1 (fr) | 2000-04-20 |
CN1200654C (zh) | 2005-05-11 |
TW425279B (en) | 2001-03-11 |
FR2784284B1 (fr) | 2000-12-15 |
DE69919883D1 (de) | 2004-10-07 |
DE69919883T2 (de) | 2005-09-15 |
PL347108A1 (en) | 2002-03-25 |
ES2229769T3 (es) | 2005-04-16 |
KR20010088865A (ko) | 2001-09-28 |
JP4088039B2 (ja) | 2008-05-21 |
BR9914448A (pt) | 2001-07-03 |
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