BR9914448A - Processo de fabricação de um implante dentário, dispositivo de cultura de células, e implante dentário - Google Patents

Processo de fabricação de um implante dentário, dispositivo de cultura de células, e implante dentário

Info

Publication number
BR9914448A
BR9914448A BR9914448-4A BR9914448A BR9914448A BR 9914448 A BR9914448 A BR 9914448A BR 9914448 A BR9914448 A BR 9914448A BR 9914448 A BR9914448 A BR 9914448A
Authority
BR
Brazil
Prior art keywords
dental implant
implant
root part
dental
cell culture
Prior art date
Application number
BR9914448-4A
Other languages
English (en)
Inventor
Philippe Gault
Original Assignee
Natural Implant Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natural Implant Sa filed Critical Natural Implant Sa
Publication of BR9914448A publication Critical patent/BR9914448A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3865—Dental/periodontal tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/10—Petri dish
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/38—Caps; Covers; Plugs; Pouring means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/14—Rotation or movement of the cells support, e.g. rotated hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ceramic Engineering (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

"PROCESSO DE FABRICAçãO DE UM IMPLANTE DENTáRIO, DISPOSITIVO DE CULTURA DE CéLULAS, E IMPLANTE DENTáRIO. A presente invenção refere-se a um processo de fabricação de um implante dentário compreendendo a preparação de um implante composto de uma parte radicular e uma parte coronária e constituído de um material inerte biocompatível de acordo com uma forma adaptada a um dente extraído; a imersão da parte radicular deste implante em uma cultura de células mesenquimais indiferenciadas, em um meio de cultura cuja composição permite a diferenciação em cimentoblastos e em fibroblastos, durante um tempo suficiente para esta diferenciação, à adesão dos cimentoblastos sobre a parte radicular, à formação de uma primeira camada de cimento e uma massa intermediária de ligamento alveolo-dentário fixada neste cimento; e a coleta do implante portador de tecidos diferenciadas fixados em sua parte radicular.
BR9914448-4A 1998-10-13 1999-10-12 Processo de fabricação de um implante dentário, dispositivo de cultura de células, e implante dentário BR9914448A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9812831A FR2784284B1 (fr) 1998-10-13 1998-10-13 Procede de preparation d'un implant dentaire par immersion dans une culture de cellules mesenchymateuses, dispositif de culture de cellules pour la preparation dudit implant et implant obtenu
PCT/FR1999/002462 WO2000021456A1 (fr) 1998-10-13 1999-10-12 Procede et dispositif de preparation d'un implant dentaire par immersion dans une culture de cellules mesenchymateuses

Publications (1)

Publication Number Publication Date
BR9914448A true BR9914448A (pt) 2001-07-03

Family

ID=9531511

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914448-4A BR9914448A (pt) 1998-10-13 1999-10-12 Processo de fabricação de um implante dentário, dispositivo de cultura de células, e implante dentário

Country Status (18)

Country Link
US (1) US6589525B2 (pt)
EP (1) EP1121064B1 (pt)
JP (1) JP4088039B2 (pt)
KR (1) KR100602858B1 (pt)
CN (1) CN1200654C (pt)
AT (1) ATE274862T1 (pt)
AU (1) AU757566B2 (pt)
BR (1) BR9914448A (pt)
CA (1) CA2346555C (pt)
DE (1) DE69919883T2 (pt)
DK (1) DK1121064T3 (pt)
ES (1) ES2229769T3 (pt)
FR (1) FR2784284B1 (pt)
IL (1) IL142302A (pt)
PL (1) PL192841B1 (pt)
PT (1) PT1121064E (pt)
TW (1) TW425279B (pt)
WO (1) WO2000021456A1 (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2179731B1 (es) * 2000-04-14 2004-04-16 Alberto Arruga Artal Implante dental y metodo operativo de implantacion.
FR2819395B1 (fr) 2001-01-12 2003-08-15 Natural Implant Sa Implant dentaire transitoire de preparation d'une alveole
FR2821853B1 (fr) * 2001-03-09 2003-05-16 Natural Implant Sa Bioreacteur pour tissu cultive en couche mince et utilisations
JPWO2003101502A1 (ja) * 2002-05-31 2005-10-27 上田　実 歯胚の再生方法および再生歯胚
US20060177386A1 (en) * 2002-05-31 2006-08-10 Minoru Ueda Method of regenerating tooth germ and a regenerated tooth germ
KR100644296B1 (ko) * 2004-07-24 2006-11-10 정필훈 생체 공학적 턱뼈 및 치아 재건 방법
JP4723937B2 (ja) * 2005-07-13 2011-07-13 株式会社カネカ 細胞の播種方法
EP1914300B1 (en) * 2005-07-29 2013-08-21 Matsumoto Dental University Tooth regeneration method
US10426578B2 (en) * 2006-10-16 2019-10-01 Natural Dental Implants, Ag Customized dental prosthesis for periodontal or osseointegration and related systems
US8454362B2 (en) * 2006-10-16 2013-06-04 Natural Dental Implants Ag Customized dental prosthesis for periodontal- or osseointegration, and related systems and methods
US7708557B2 (en) * 2006-10-16 2010-05-04 Natural Dental Implants Ag Customized dental prosthesis for periodontal- or osseointegration, and related systems and methods
US8602780B2 (en) * 2006-10-16 2013-12-10 Natural Dental Implants, Ag Customized dental prosthesis for periodontal or osseointegration and related systems and methods
US9801697B2 (en) * 2011-03-18 2017-10-31 Natural Dental Implants Ag Integrated support device for providing temporary primary stability to dental implants and prosthesis, and related methods
US9539062B2 (en) 2006-10-16 2017-01-10 Natural Dental Implants, Ag Methods of designing and manufacturing customized dental prosthesis for periodontal or osseointegration and related systems
US10232080B2 (en) * 2006-11-29 2019-03-19 University Of Southern California Mesenchymal stem cell-mediated function tooth regeneration
PL2200622T5 (pl) * 2007-09-19 2016-08-31 Pluristem Ltd Adherentne komórki z tkanki tłuszczowej i łożyska i ich zastosowanie w terapii
JPWO2010021162A1 (ja) * 2008-08-19 2012-01-26 国立大学法人大阪大学 骨組織再生用の細胞製剤
DE102008049014A1 (de) * 2008-09-25 2010-04-22 Bagambisa, Frank, Dr. Dentalimplantat zur Implantation in einen menschlichen oder tierischen Kieferknochen und Verfahren zu seiner Herstellung
WO2011114218A2 (en) * 2010-03-16 2011-09-22 Bertoni Hernan Gabriel Endograft with cultured stem cells
US9606035B2 (en) 2011-12-21 2017-03-28 Ta Instruments-Waters Llc System for mechanical stimulation and characterization of biologic samples
EP2823787B1 (en) * 2012-02-01 2019-01-09 Organ Technologies, Inc. Dental implant and method for producing same
CN104981547A (zh) * 2012-12-26 2015-10-14 石匠株式会社 高功能植入体材料
WO2015106247A1 (en) 2014-01-13 2015-07-16 Westover Brock B Endosseous dental implant assembly
JP6338214B2 (ja) * 2014-03-28 2018-06-06 国立研究開発法人国立長寿医療研究センター インプラント体
GB2555901B (en) * 2016-08-26 2019-11-13 Tran Scell Biologics Private Ltd Method of preparation of a novel stem cell-biocomplex for clinical implantation in periodontal space
RU2649452C1 (ru) * 2017-06-07 2018-04-03 Дмитрий Андреевич Журавлёв Способ имплантации искусственного зуба
CN111484936B (zh) * 2020-05-21 2021-04-02 吉林大学中日联谊医院 一种结直肠癌实体瘤原代细胞的培养装置及培养方法
WO2024201321A1 (en) * 2023-03-28 2024-10-03 Nanodent S.R.L. Novel process
CN117947138B (zh) * 2024-03-27 2024-06-21 佳木斯大学 一种口腔材料体外细胞毒性测试方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4872840A (en) * 1987-07-15 1989-10-10 Team Incorporated Dental implant and method
JPH01299563A (ja) * 1988-05-28 1989-12-04 Moritsugu Ootori インプラント材のポーラス部封孔処理方法
DE4040872C3 (de) 1990-12-20 2000-08-24 Klaus Ursus Schendel Implantat für den Dentalbereich
DE4222296A1 (de) 1990-12-20 1993-12-23 Klaus Ursus Dr Dr Schendel Implantat für den Dentalberiech und Verfahren zu seiner Herstellung
JP3471967B2 (ja) * 1995-03-28 2003-12-02 カネボウ株式会社 ハイブリッド型人工歯根
EP0915967A1 (en) * 1996-05-28 1999-05-19 The Board Of Regents Of The University Of Michigan Engineering oral tissues

Also Published As

Publication number Publication date
CA2346555C (fr) 2007-12-04
TW425279B (en) 2001-03-11
JP4088039B2 (ja) 2008-05-21
AU757566B2 (en) 2003-02-27
KR100602858B1 (ko) 2006-07-20
DK1121064T3 (da) 2005-01-10
DE69919883D1 (de) 2004-10-07
CA2346555A1 (fr) 2000-04-20
AU6095699A (en) 2000-05-01
IL142302A (en) 2005-06-19
FR2784284A1 (fr) 2000-04-14
US20010055745A1 (en) 2001-12-27
CN1323181A (zh) 2001-11-21
DE69919883T2 (de) 2005-09-15
US6589525B2 (en) 2003-07-08
ATE274862T1 (de) 2004-09-15
WO2000021456A1 (fr) 2000-04-20
IL142302A0 (en) 2002-03-10
JP2002527139A (ja) 2002-08-27
PT1121064E (pt) 2005-01-31
KR20010088865A (ko) 2001-09-28
PL347108A1 (en) 2002-03-25
CN1200654C (zh) 2005-05-11
ES2229769T3 (es) 2005-04-16
FR2784284B1 (fr) 2000-12-15
EP1121064B1 (fr) 2004-09-01
PL192841B1 (pl) 2006-12-29
EP1121064A1 (fr) 2001-08-08

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