ATE513901T1 - Neurale vorläuferzellen - Google Patents
Neurale vorläuferzellenInfo
- Publication number
- ATE513901T1 ATE513901T1 AT08075134T AT08075134T ATE513901T1 AT E513901 T1 ATE513901 T1 AT E513901T1 AT 08075134 T AT08075134 T AT 08075134T AT 08075134 T AT08075134 T AT 08075134T AT E513901 T1 ATE513901 T1 AT E513901T1
- Authority
- AT
- Austria
- Prior art keywords
- neural progenitor
- progenitor cells
- cells
- precursor cells
- mass
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1353—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from bone marrow mesenchymal stem cells (BM-MSC)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33495701P | 2001-10-25 | 2001-10-25 | |
US10/253,759 US7129034B2 (en) | 2001-10-25 | 2002-09-24 | Differentiation of whole bone marrow |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE513901T1 true ATE513901T1 (de) | 2011-07-15 |
Family
ID=26943536
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08075134T ATE513901T1 (de) | 2001-10-25 | 2002-10-18 | Neurale vorläuferzellen |
AT02784173T ATE387491T1 (de) | 2001-10-25 | 2002-10-18 | Differenzierung vom gesamten knochenmark |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02784173T ATE387491T1 (de) | 2001-10-25 | 2002-10-18 | Differenzierung vom gesamten knochenmark |
Country Status (6)
Country | Link |
---|---|
US (5) | US7129034B2 (de) |
EP (2) | EP1438393B1 (de) |
JP (2) | JP2005531279A (de) |
AT (2) | ATE513901T1 (de) |
DE (1) | DE60225310T2 (de) |
WO (1) | WO2003035855A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7129034B2 (en) * | 2001-10-25 | 2006-10-31 | Cedars-Sinai Medical Center | Differentiation of whole bone marrow |
ATE398105T1 (de) | 2002-03-13 | 2008-07-15 | Janssen Pharmaceutica Nv | Carbonylamino- derivativate als neue inhibitoren von histone deacetylase |
EA007272B1 (ru) | 2002-03-13 | 2006-08-25 | Янссен Фармацевтика Н. В. | Новые ингибиторы гистондеацетилазы |
US7875273B2 (en) | 2004-12-23 | 2011-01-25 | Ethicon, Incorporated | Treatment of Parkinson's disease and related disorders using postpartum derived cells |
ES2564044T3 (es) | 2003-06-27 | 2016-03-17 | DePuy Synthes Products, Inc. | Células posparto derivadas de tejido del cordón umbilical y métodos de preparación y uso de las mismas |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
US8491883B2 (en) * | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
US20060223177A1 (en) | 2003-06-27 | 2006-10-05 | Ethicon Inc. | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
WO2005003320A2 (en) * | 2003-07-02 | 2005-01-13 | Regents Of The University Of Minnesota | Neuronal differentiation of stem cells |
EP1506997A1 (de) * | 2003-08-14 | 2005-02-16 | NeuroProgen GmbH Leipzig | Verfahren zur Erzeugung von neuronalen Stammzellen |
US20070269412A1 (en) * | 2003-12-02 | 2007-11-22 | Celavie Biosciences, Llc | Pluripotent cells |
JP2008505650A (ja) * | 2004-07-12 | 2008-02-28 | ソリン・グループ・イタリア・ソシエタ・ア・レスポンサビリタ・リミタータ | ヒト細胞を増殖させるための装置及び方法 |
SG156687A1 (en) | 2004-07-28 | 2009-11-26 | Janssen Pharmaceutica Nv | Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase |
WO2006101548A2 (en) * | 2004-12-21 | 2006-09-28 | Ethicon, Inc. | Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same |
US20060153815A1 (en) * | 2004-12-21 | 2006-07-13 | Agnieszka Seyda | Tissue engineering devices for the repair and regeneration of tissue |
WO2006083394A2 (en) * | 2004-12-21 | 2006-08-10 | Ethicon, Inc. | Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same |
JP4905719B2 (ja) * | 2005-02-10 | 2012-03-28 | 公益財団法人新産業創造研究機構 | 神経幹細胞の調製法 |
US20060183712A1 (en) * | 2005-02-17 | 2006-08-17 | The Texas A&M University System | Affinity purified heparin/heparan sulfate for controlling the biological activity of the FGF receptor |
WO2006096640A2 (en) * | 2005-03-07 | 2006-09-14 | Sanbio Inc. | Use of neuronal precursor cells for treatment of central nervous system lesions |
ATE509920T1 (de) | 2005-10-27 | 2011-06-15 | Janssen Pharmaceutica Nv | Quadratsäurederivate als inhibitoren von histondeacetylase |
PL1971681T3 (pl) * | 2005-12-16 | 2018-01-31 | Depuy Synthes Products Inc | Kompozycje oraz sposoby do hamowania niepożądanej odpowiedzi immunologicznej w przypadku transplantacji z brakiem zgodności tkankowej |
WO2007073552A1 (en) * | 2005-12-19 | 2007-06-28 | Ethicon, Inc. | In vitro expansion of postpartum derived cells in roller bottles |
ES2628129T3 (es) * | 2005-12-28 | 2017-08-01 | DePuy Synthes Products, Inc. | Tratamiento de la enfermedad vascular periférica utilizando células derivadas del posparto |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
JP5247470B2 (ja) | 2006-01-19 | 2013-07-24 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ヒストンデアセチラーゼのインヒビターとしてのピリジン及びピリミジン誘導体 |
US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
WO2008137115A1 (en) | 2007-05-03 | 2008-11-13 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
US20090081276A1 (en) * | 2007-08-13 | 2009-03-26 | Eben Alsberg | Bioresorbable implant composition |
ES2525718T3 (es) * | 2007-10-05 | 2014-12-29 | DePuy Synthes Products, LLC | Reparación y regeneración de tejido renal mediante células derivadas de tejido de cordón umbilical humano |
US20110306137A1 (en) | 2007-12-03 | 2011-12-15 | Irina Aizman | Methods and compositions for modulating differentiation of pluripotential cells |
US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
US9198597B2 (en) * | 2008-05-22 | 2015-12-01 | Christopher Duma | Leading-edge cancer treatment |
CA2747794C (en) | 2008-12-19 | 2018-10-30 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of lung and pulmonary diseases and disorders |
US10179900B2 (en) * | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
EP2379089B1 (de) * | 2008-12-19 | 2019-04-17 | DePuy Synthes Products, Inc. | Regeneration und reparatur von nervengeweben nach einer verletzung |
AU2009327382B2 (en) * | 2008-12-19 | 2014-07-17 | DePuy Synthes Products, LLC | Umbilical cord tissue derived cells for treating neuropathic pain and spasticity |
US20100209399A1 (en) * | 2009-02-13 | 2010-08-19 | Celavie Biosciences, Llc | Brain-derived stem cells for repair of musculoskeletal system in vertebrate subjects |
SG174551A1 (en) * | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
US9109206B2 (en) | 2009-10-16 | 2015-08-18 | Rutgers, The State University Of New Jersey | Method for treating chronic nerve tissue injury using a cell therapy strategy |
PL2794854T3 (pl) | 2011-12-23 | 2018-12-31 | DePuy Synthes Products, Inc. | Wykrywanie ludzkich komórek pochodzących z tkanki pępowinowej |
AU2014236150B2 (en) | 2013-03-14 | 2019-10-31 | The Regents Of The University Of California | In vitro production of medial ganglionic eminence precursor cells |
US11464804B1 (en) | 2017-11-15 | 2022-10-11 | Enrico Stazzone | Intrathecal multifactorial infusion of heterogeneous autologous cell therapy |
Family Cites Families (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5130144B1 (en) * | 1984-02-06 | 1995-08-15 | Univ Johns Hopkins | Human stem cells and monoclonal antibodies |
US4965204A (en) * | 1984-02-06 | 1990-10-23 | The Johns Hopkins University | Human stem cells and monoclonal antibodies |
US4714680B1 (en) * | 1984-02-06 | 1995-06-27 | Univ Johns Hopkins | Human stem cells |
AU623922B2 (en) * | 1988-08-04 | 1992-05-28 | Amrad Operations Pty. Limited | In vitro propagation of embryonic stem cells |
US5399493A (en) * | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
US5437994A (en) * | 1989-06-15 | 1995-08-01 | Regents Of The University Of Michigan | Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
US5061620A (en) * | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
US5612211A (en) * | 1990-06-08 | 1997-03-18 | New York University | Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors |
US5556783A (en) * | 1991-03-27 | 1996-09-17 | Trustees Of Univ. Of Penna | Methods of culturing and modulating the growth of hair follicular stem cells |
US5367057A (en) * | 1991-04-02 | 1994-11-22 | The Trustees Of Princeton University | Tyrosine kinase receptor flk-2 and fragments thereof |
US5851832A (en) * | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
US5429938A (en) * | 1992-03-02 | 1995-07-04 | University Of Michigan | Methods and compositions for isolation and growth of kidney tubule stem cells, in vitro kidney tubulogenesis and ex vivo construction of renal tubules |
US5436151A (en) * | 1992-04-03 | 1995-07-25 | Regents Of The University Of Minnesota | Method for culturing human hematopoietic stem cells in vitro |
US5589376A (en) * | 1992-07-27 | 1996-12-31 | California Institute Of Technology | Mammalian neural crest stem cells |
US5654183A (en) * | 1992-07-27 | 1997-08-05 | California Institute Of Technology | Genetically engineered mammalian neural crest stem cells |
AU678988B2 (en) * | 1992-07-27 | 1997-06-19 | California Institute Of Technology | Mammalian multipotent neural stem cells |
US5849553A (en) * | 1992-07-27 | 1998-12-15 | California Institute Of Technology | Mammalian multipotent neural stem cells |
US5928947A (en) * | 1992-07-27 | 1999-07-27 | California Institute Of Technology | Mammalian multipotent neural stem cells |
US5766948A (en) * | 1993-01-06 | 1998-06-16 | The Regents Of The University Of California | Method for production of neuroblasts |
GB9308271D0 (en) | 1993-04-21 | 1993-06-02 | Univ Edinburgh | Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method |
US5772994A (en) * | 1993-05-28 | 1998-06-30 | The University Of Pittsburgh | Hematopoietic facilitatory cells and their uses |
AU685506B2 (en) * | 1993-08-25 | 1998-01-22 | Systemix, Inc. | Method for producing a highly enriched population of hematopoietic stem cells |
IL107483A0 (en) * | 1993-11-03 | 1994-02-27 | Yeda Res & Dev | Bone marrow transplantation |
US5599705A (en) | 1993-11-16 | 1997-02-04 | Cameron; Robert B. | In vitro method for producing differentiated universally compatible mature human blood cells |
US5449620A (en) * | 1994-01-25 | 1995-09-12 | Thomas Jefferson University | Apparatus and method for culturing embryonic stem cells |
JPH10505754A (ja) | 1994-09-23 | 1998-06-09 | ニューロスフィアーズ ホウルディングス リミテッド | Cns機能及び機能障害インビトロモデル |
US6204053B1 (en) * | 1994-11-08 | 2001-03-20 | Diacrin, Inc. | Porcine cortical cells and their use in treatment of neurological deficits due to neurodegenerative diseases |
US5665557A (en) * | 1994-11-14 | 1997-09-09 | Systemix, Inc. | Method of purifying a population of cells enriched for hematopoietic stem cells populations of cells obtained thereby and methods of use thereof |
CN1170435A (zh) | 1994-11-14 | 1998-01-14 | 纽罗斯菲里斯控股有限公司 | 神经干细胞增殖的调节 |
US5677136A (en) * | 1994-11-14 | 1997-10-14 | Systemix, Inc. | Methods of obtaining compositions enriched for hematopoietic stem cells, compositions derived therefrom and methods of use thereof |
US5728581A (en) * | 1995-06-07 | 1998-03-17 | Systemix, Inc. | Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein |
US5753506A (en) * | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
EP0941027A4 (de) * | 1996-11-15 | 2000-08-09 | Osiris Therapeutics Inc | MSC-Megakaryozytenvorläuferzusammensetzung und Verfahren zum Isolieren von mit isolierten Megakaryozyten assoziierten MSCS durch die Isolierung von Megakaryozyten |
US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
WO1999056759A1 (en) * | 1998-05-07 | 1999-11-11 | University Of South Florida | Bone marrow cells as a source of neurons for brain and spinal cord repair |
US5958767A (en) * | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
US20020115213A1 (en) * | 1998-08-14 | 2002-08-22 | Northeastern Ohio Universities Of Medicine | Engraftable neural progenitor & stem cells for brain tumor therapy |
US7186409B2 (en) * | 1998-08-14 | 2007-03-06 | The Children's Medical Center Corporation | Neural stem cells and use thereof for brain tumor therapy |
ES2290032T3 (es) | 1999-05-03 | 2008-02-16 | Neuro Therapeutics Ab | Procedimiento para la produccion de neuronas dopaminergicas. |
EP1263930A4 (de) | 2000-03-09 | 2004-07-21 | Saneron Ccel Therapeutics Inc | Menschliches nabelschnurblut als quelle für neurales gewebe zur heilung von gehirn und rückenmark |
AU4744201A (en) * | 2000-03-15 | 2001-09-24 | Childrens Medical Center | Systemic gene delivery vehicles for the treatment of tumors |
JP5943533B2 (ja) * | 2000-05-17 | 2016-07-06 | アステリアス バイオセラピューティクス インコーポレイテッド | 神経前駆細胞の集団 |
US20040092013A1 (en) * | 2001-08-14 | 2004-05-13 | Snyder Evan Y. | Method of treating alzheimer's disease with cell therapy |
US9969980B2 (en) * | 2001-09-21 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
US7129034B2 (en) | 2001-10-25 | 2006-10-31 | Cedars-Sinai Medical Center | Differentiation of whole bone marrow |
US6842541B2 (en) * | 2001-10-31 | 2005-01-11 | Xerox Corporation | Adaptive color super resolution thresholding |
CA2470707C (en) * | 2001-12-21 | 2014-07-08 | Mount Sinai Hospital | Cellular compositions and methods of making and using them |
US20070244046A1 (en) * | 2006-03-29 | 2007-10-18 | Margarita Gutova | Identification and characterization of cancer stem cells and methods of use |
-
2002
- 2002-09-24 US US10/253,759 patent/US7129034B2/en not_active Expired - Lifetime
- 2002-10-18 AT AT08075134T patent/ATE513901T1/de not_active IP Right Cessation
- 2002-10-18 EP EP02784173A patent/EP1438393B1/de not_active Expired - Lifetime
- 2002-10-18 JP JP2003538356A patent/JP2005531279A/ja active Pending
- 2002-10-18 DE DE60225310T patent/DE60225310T2/de not_active Expired - Lifetime
- 2002-10-18 EP EP08075134A patent/EP1956079B1/de not_active Expired - Lifetime
- 2002-10-18 WO PCT/US2002/033447 patent/WO2003035855A1/en active IP Right Grant
- 2002-10-18 AT AT02784173T patent/ATE387491T1/de not_active IP Right Cessation
-
2005
- 2005-09-23 US US11/234,520 patent/US20060029580A1/en not_active Abandoned
-
2006
- 2006-02-28 US US11/364,394 patent/US7504100B2/en not_active Expired - Lifetime
- 2006-02-28 US US11/364,454 patent/US20060148083A1/en not_active Abandoned
- 2006-05-15 US US11/433,996 patent/US8071366B2/en not_active Expired - Fee Related
-
2007
- 2007-12-27 JP JP2007338253A patent/JP2008099709A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1438393A1 (de) | 2004-07-21 |
US7504100B2 (en) | 2009-03-17 |
US20060148083A1 (en) | 2006-07-06 |
US20060148082A1 (en) | 2006-07-06 |
WO2003035855A1 (en) | 2003-05-01 |
DE60225310D1 (de) | 2008-04-10 |
US20060205074A1 (en) | 2006-09-14 |
EP1956079B1 (de) | 2011-06-22 |
JP2008099709A (ja) | 2008-05-01 |
JP2005531279A (ja) | 2005-10-20 |
US20030082160A1 (en) | 2003-05-01 |
US20060029580A1 (en) | 2006-02-09 |
US8071366B2 (en) | 2011-12-06 |
EP1438393B1 (de) | 2008-02-27 |
EP1956079A1 (de) | 2008-08-13 |
ATE387491T1 (de) | 2008-03-15 |
DE60225310T2 (de) | 2009-03-12 |
US7129034B2 (en) | 2006-10-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE513901T1 (de) | Neurale vorläuferzellen | |
HK1071162A1 (en) | Method for differentiating mesenchymal stem cells into neural cells | |
DE60044690D1 (de) | Verfahren zur Herstellung von rekombinanten Proteinen mittels Inhibitoren von Apoptose | |
DK1121064T3 (da) | Fremgangsmåde og indretning til præparering af et tandomplantat ved nedsænkning i en kultur af mesenkymatöse celler | |
IL192762A0 (en) | Method for identifying cell differentiation factors | |
DE60017875D1 (de) | Verwendung von collagenase in der zubereitung von neuralen stammzellkulturen | |
DE69933579D1 (de) | Serum-freies medium für chondrozyt-ähnliche zellen | |
CA2416801A1 (en) | Adult human dental pulp stem cells in vitro and in vivo | |
PT1218509E (pt) | Polipéptidos do tipo factor de crescimento de fibroblastos | |
BR0214217A (pt) | Aumento de função de órgão | |
BR9917026B1 (pt) | método para fabricar glicoproteìnas tendo glicosilação do tipo humano. | |
EP1406643A4 (de) | Physiologische gewebereparatur und funktionale organregeneration durch kultivierung von regenerativen stammzellen in vivo und in situ | |
WO2003024406A3 (en) | Nestin-expressing hair follicle stem cells | |
DK1551954T3 (da) | Cellekultur | |
DK1242578T3 (da) | Celledyrkningsmedium indeholdende vækstfaktorer og L-glutamin | |
ATE345496T1 (de) | In-vitro-musters für zns - funktion und dysfunktion | |
DK0946199T3 (da) | TGF betal 1-responsive celler fra knoglemarv | |
WO2003089581A3 (en) | A method to increase the rate of cell growth | |
GR3032105T3 (en) | Callus cell induction and the preparation of taxanes. | |
WO2000070022A3 (en) | Ex vivo expansion of mammalian hematopoietic stem cells | |
DE60326003D1 (de) | Ter verwendung des hepatozytenwachstumsfaktors | |
EP1229111A3 (de) | Kultivierte Zellen aus Ficus stipulata thunb. (= Ficus thunbergii) und ein Verfahren zur Züchtung von Ficus stipulata Geweben unter Verwendung dieser kultivierten Zellen | |
TW200617165A (en) | Process for preparing a conditioned medium of astrocyte-like cells | |
DE50212759D1 (de) | Medium zur züchtung von tumorzellen | |
DE60208173D1 (de) | Produktion von genetisch geänderten pflanzen mit püroindoline |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |