IL141955A0 - Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents

Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL141955A0
IL141955A0 IL14195596A IL14195596A IL141955A0 IL 141955 A0 IL141955 A0 IL 141955A0 IL 14195596 A IL14195596 A IL 14195596A IL 14195596 A IL14195596 A IL 14195596A IL 141955 A0 IL141955 A0 IL 141955A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
benzothiazolone derivatives
benzothiazolone
Prior art date
Application number
IL14195596A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9518952.8A external-priority patent/GB9518952D0/en
Priority claimed from GBGB9614346.6A external-priority patent/GB9614346D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IL141955A0 publication Critical patent/IL141955A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/04—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
    • C07C311/24—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL14195596A 1995-09-15 1996-09-12 Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them IL141955A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9518952.8A GB9518952D0 (en) 1995-09-15 1995-09-15 Compounds
GBGB9614346.6A GB9614346D0 (en) 1996-07-10 1996-07-10 Benzothiazolone derivatives
IL12363996A IL123639A (en) 1995-09-15 1996-09-12 History of benzothiazole, process for their preparation and pharmaceutical compounds containing them
PCT/GB1996/002247 WO1997010227A1 (en) 1995-09-15 1996-09-12 Benzothiazolone derivatives

Publications (1)

Publication Number Publication Date
IL141955A0 true IL141955A0 (en) 2002-03-10

Family

ID=26307771

Family Applications (4)

Application Number Title Priority Date Filing Date
IL14195696A IL141956A0 (en) 1995-09-15 1996-09-12 Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them
IL141954??A IL141954A0 (en) 1995-09-15 1996-09-12 Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them
IL12363996A IL123639A (en) 1995-09-15 1996-09-12 History of benzothiazole, process for their preparation and pharmaceutical compounds containing them
IL14195596A IL141955A0 (en) 1995-09-15 1996-09-12 Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them

Family Applications Before (3)

Application Number Title Priority Date Filing Date
IL14195696A IL141956A0 (en) 1995-09-15 1996-09-12 Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them
IL141954??A IL141954A0 (en) 1995-09-15 1996-09-12 Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them
IL12363996A IL123639A (en) 1995-09-15 1996-09-12 History of benzothiazole, process for their preparation and pharmaceutical compounds containing them

Country Status (29)

Country Link
US (5) US5846989A (xx)
EP (1) EP0850232B1 (xx)
JP (1) JP3213327B2 (xx)
KR (1) KR19990044674A (xx)
CN (2) CN1073098C (xx)
AR (1) AR004512A1 (xx)
AT (1) ATE190610T1 (xx)
AU (1) AU706094B2 (xx)
BR (1) BR9610316A (xx)
CA (1) CA2231003A1 (xx)
CY (1) CY2227B1 (xx)
CZ (1) CZ74098A3 (xx)
DE (1) DE69607183T2 (xx)
EE (1) EE03395B1 (xx)
ES (1) ES2146901T3 (xx)
GR (1) GR3033681T3 (xx)
HK (1) HK1008781A1 (xx)
HU (1) HUP9802393A3 (xx)
IL (4) IL141956A0 (xx)
IS (1) IS4679A (xx)
MY (1) MY113518A (xx)
NO (1) NO310721B1 (xx)
NZ (4) NZ318007A (xx)
PL (1) PL325517A1 (xx)
PT (1) PT850232E (xx)
SK (1) SK282394B6 (xx)
TR (1) TR199800457T2 (xx)
TW (1) TW356468B (xx)
WO (1) WO1997010227A1 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2287617T3 (es) * 1997-10-17 2007-12-16 Ark Therapeutics Limited Utilizacion de inhibidores del sistema renina-angiotensina.
SE0004750D0 (sv) * 2000-12-19 2000-12-19 Astrazeneca Ab Novel formulation
PE20050130A1 (es) * 2002-08-09 2005-03-29 Novartis Ag Compuestos organicos
GB0218629D0 (en) * 2002-08-09 2002-09-18 Novartis Ag Organic compounds
JP4851937B2 (ja) 2003-11-21 2012-01-11 セラヴァンス， インコーポレーテッド β２アドレナリン作動性受容体作動薬活性およびムスカリン受容体拮抗薬活性を有する化合物
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
TW200738658A (en) * 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
CN101282950B (zh) * 2005-08-09 2012-09-12 阿斯利康(瑞典)有限公司 新颖的苯并噻唑酮衍生物
TW200740781A (en) * 2005-08-29 2007-11-01 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
TW200833670A (en) * 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
BRPI0722095A2 (pt) * 2006-12-20 2014-04-01 Astrazeneca Ab Derivados de amina e seu uso em doenças mediadas por beta-2-adrenor-receptor
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
CN102124003A (zh) 2008-06-18 2011-07-13 阿斯利康(瑞典)有限公司 作为治疗呼吸系统疾病的β2肾上腺素受体拮抗剂的苯并噁嗪酮衍生物
KR20110022611A (ko) * 2008-06-20 2011-03-07 아스트라제네카 아베 베타２－아드레날린수용체 활성의 조절을 위한, ４－히드록시－２－옥소－２,３－디히드로－１,３－벤조티아졸－７－일 화합물을 포함하는 제약 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314944A (en) * 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
GB8426200D0 (en) * 1984-10-17 1984-11-21 Glaxo Holdings Ltd Chemical compounds
US4554287A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones
US4554284A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones
EP0180994A3 (en) * 1984-11-08 1987-09-23 Syntex (U.S.A.) Inc. Antihypertensive dialkyl aminoethylaniline derivatives
DE3728695A1 (de) * 1987-08-25 1989-03-09 Schering Ag Neue benzimidazol-derivate
GB9024208D0 (en) * 1990-11-07 1990-12-19 Salutar Inc Compounds
GB9210632D0 (en) * 1992-05-19 1992-07-01 Fisons Plc Compounds
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines
GB9211172D0 (en) * 1992-05-27 1992-07-08 Fisons Plc Compounds

Also Published As

Publication number Publication date
IL123639A (en) 2002-04-21
CN1073098C (zh) 2001-10-17
NZ332395A (en) 1999-02-25
EE03395B1 (et) 2001-04-16
NZ332397A (en) 1999-02-25
EP0850232B1 (en) 2000-03-15
AU706094B2 (en) 1999-06-10
MX9801963A (es) 1998-08-30
BR9610316A (pt) 1999-07-06
US5977384A (en) 1999-11-02
JPH11512422A (ja) 1999-10-26
IL141956A0 (en) 2002-03-10
TW356468B (en) 1999-04-21
MY113518A (en) 2002-03-30
TR199800457T2 (xx) 1998-07-21
SK29598A3 (en) 1999-01-11
CY2227B1 (en) 2003-04-18
AU6937196A (en) 1997-04-01
NO310721B1 (no) 2001-08-20
PT850232E (pt) 2000-08-31
NO981104D0 (no) 1998-03-12
AR004512A1 (es) 1998-12-16
HUP9802393A3 (en) 2000-01-28
WO1997010227A1 (en) 1997-03-20
ATE190610T1 (de) 2000-04-15
KR19990044674A (ko) 1999-06-25
NZ332396A (en) 1999-02-25
GR3033681T3 (en) 2000-10-31
IL141954A0 (en) 2002-03-10
US6080869A (en) 2000-06-27
US5973167A (en) 1999-10-26
US5846989A (en) 1998-12-08
CZ74098A3 (cs) 1998-08-12
EP0850232A1 (en) 1998-07-01
DE69607183D1 (de) 2000-04-20
DE69607183T2 (de) 2000-11-23
SK282394B6 (sk) 2002-01-07
NO981104L (no) 1998-05-14
HUP9802393A2 (hu) 1999-04-28
HK1008781A1 (en) 1999-05-21
NZ318007A (en) 1999-07-29
CN1356323A (zh) 2002-07-03
IS4679A (is) 1998-03-04
IL123639A0 (en) 1998-10-30
JP3213327B2 (ja) 2001-10-02
CN1202163A (zh) 1998-12-16
EE9800069A (et) 1998-10-15
CA2231003A1 (en) 1997-03-20
PL325517A1 (en) 1998-08-03
ES2146901T3 (es) 2000-08-16
US6008365A (en) 1999-12-28

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