IL140062A0 - Tetrahydroquinoline derivatives as glycine antagonists - Google Patents
Tetrahydroquinoline derivatives as glycine antagonistsInfo
- Publication number
- IL140062A0 IL140062A0 IL14006299A IL14006299A IL140062A0 IL 140062 A0 IL140062 A0 IL 140062A0 IL 14006299 A IL14006299 A IL 14006299A IL 14006299 A IL14006299 A IL 14006299A IL 140062 A0 IL140062 A0 IL 140062A0
- Authority
- IL
- Israel
- Prior art keywords
- tetrahydroquinoline derivatives
- glycine antagonists
- antagonists
- glycine
- tetrahydroquinoline
- Prior art date
Links
- 229940127337 Glycine Antagonists Drugs 0.000 title 1
- 125000000147 tetrahydroquinolinyl group Chemical class N1(CCCC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9812408.4A GB9812408D0 (en) | 1998-06-10 | 1998-06-10 | Heterocyclic compounds |
| GBGB9812410.0A GB9812410D0 (en) | 1998-06-10 | 1998-06-10 | Heterocyclic derivatives |
| PCT/EP1999/003936 WO1999064411A1 (en) | 1998-06-10 | 1999-06-08 | Tetrahydroquinoline derivatives as glycine antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL140062A0 true IL140062A0 (en) | 2002-02-10 |
Family
ID=26313826
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14006299A IL140062A0 (en) | 1998-06-10 | 1999-06-08 | Tetrahydroquinoline derivatives as glycine antagonists |
| IL140062A IL140062A (en) | 1998-06-10 | 2000-12-04 | Tetrahedroquinoline Derivatives, Preparation Process, Pharmaceutical Preparations Containing It and Their Use in Preparing Medicinal Preparations to Suppress the Effect of Polarized Amino Acids on the NMDA Receptor |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL140062A IL140062A (en) | 1998-06-10 | 2000-12-04 | Tetrahedroquinoline Derivatives, Preparation Process, Pharmaceutical Preparations Containing It and Their Use in Preparing Medicinal Preparations to Suppress the Effect of Polarized Amino Acids on the NMDA Receptor |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US6362199B1 (cs) |
| EP (1) | EP1086093B1 (cs) |
| JP (1) | JP2002517492A (cs) |
| KR (1) | KR100586762B1 (cs) |
| CN (1) | CN1173970C (cs) |
| AP (1) | AP2000002008A0 (cs) |
| AR (1) | AR018632A1 (cs) |
| AT (1) | ATE301650T1 (cs) |
| AU (1) | AU753867B2 (cs) |
| BG (1) | BG105123A (cs) |
| BR (1) | BR9911145A (cs) |
| CA (1) | CA2334727C (cs) |
| CO (1) | CO5080785A1 (cs) |
| CZ (1) | CZ293605B6 (cs) |
| DE (1) | DE69926632T2 (cs) |
| DK (1) | DK1086093T3 (cs) |
| EA (1) | EA003276B1 (cs) |
| EE (1) | EE200000733A (cs) |
| ES (1) | ES2249010T3 (cs) |
| HR (1) | HRP20000845A2 (cs) |
| HU (1) | HUP0102767A3 (cs) |
| ID (1) | ID27845A (cs) |
| IL (2) | IL140062A0 (cs) |
| IS (1) | IS5746A (cs) |
| MY (1) | MY125037A (cs) |
| NO (1) | NO321904B1 (cs) |
| NZ (1) | NZ508638A (cs) |
| OA (1) | OA11564A (cs) |
| PE (1) | PE20000724A1 (cs) |
| PL (1) | PL197160B1 (cs) |
| TR (1) | TR200003652T2 (cs) |
| TW (1) | TWI229079B (cs) |
| WO (1) | WO1999064411A1 (cs) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY125037A (en) * | 1998-06-10 | 2006-07-31 | Glaxo Wellcome Spa | 1,2,3,4 tetrahydroquinoline derivatives |
| US6455734B1 (en) | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
| GB9929037D0 (en) * | 1999-12-08 | 2000-02-02 | Glaxo Wellcome Spa | Heterocyclic derivatives |
| DE10000311A1 (de) | 2000-01-05 | 2001-07-12 | Gruenenthal Gmbh | Aminomethyl-Phonyl-Cyclohexanonderivate |
| DE10005302A1 (de) * | 2000-02-07 | 2002-01-17 | Gruenenthal Gmbh | Substituierte 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate |
| DE10137487A1 (de) * | 2001-08-03 | 2003-03-27 | Gruenenthal Gmbh | Substituierte 5,6,6a,11b-Tetrahydro-7-oxa-6-aza- benzo[c]fluoren-6-carbonsäurederivate |
| DE10137488A1 (de) * | 2001-08-03 | 2003-02-20 | Gruenenthal Gmbh | Salze substituierter 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate |
| CA2500582A1 (en) * | 2002-10-04 | 2004-04-22 | Millennium Pharmaceuticals, Inc. | Pgd2 receptor antagonists for the treatment of inflammatory diseases |
| US7504508B2 (en) * | 2002-10-04 | 2009-03-17 | Millennium Pharmaceuticals, Inc. | PGD2 receptor antagonists for the treatment of inflammatory diseases |
| US20090181966A1 (en) * | 2002-10-04 | 2009-07-16 | Millennium Pharmaceuticals, Inc. | PGD2 receptor antagonists for the treatment of inflammatory diseases |
| GB0327912D0 (en) * | 2003-12-02 | 2004-01-07 | Glaxo Group Ltd | Medicament |
| US7951950B2 (en) * | 2005-02-24 | 2011-05-31 | Millennium Pharmaceuticals, Inc. | PGD2 receptor antagonists for the treatment of inflammatory diseases |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2024516C1 (ru) * | 1989-02-02 | 1994-12-15 | Яманути Фармасьютикал Ко., Лтд. | Способ получения производного тетрагидробензимидазола или его фармацевтически приемлемой соли |
| US4902695A (en) * | 1989-02-13 | 1990-02-20 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| US5231102A (en) * | 1989-03-08 | 1993-07-27 | Merck Sharp & Dohme, Ltd. | Tetrahydroquinoline derivatives useful for neurodegenerative disorders |
| DE69029668T2 (de) * | 1989-03-08 | 1997-08-07 | Merck Sharp & Dohme | Tetrahydroquinolin-Derivate, verwendbar bei neurodegenerativen Krankheiten |
| US5529999A (en) | 1994-03-04 | 1996-06-25 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
| TR199800531T1 (xx) * | 1995-09-29 | 1998-06-22 | Glaxo Wellcome Spa | NMDA antagonistleri olarak tetrahidrokinolinler. |
| GB9617305D0 (en) * | 1996-08-17 | 1996-09-25 | Glaxo Wellcome Spa | Heterocyclic compounds |
| MY125037A (en) * | 1998-06-10 | 2006-07-31 | Glaxo Wellcome Spa | 1,2,3,4 tetrahydroquinoline derivatives |
-
1999
- 1999-06-07 MY MYPI99002298A patent/MY125037A/en unknown
- 1999-06-08 EE EEP200000733A patent/EE200000733A/xx unknown
- 1999-06-08 WO PCT/EP1999/003936 patent/WO1999064411A1/en active IP Right Grant
- 1999-06-08 TR TR2000/03652T patent/TR200003652T2/xx unknown
- 1999-06-08 CO CO99035699A patent/CO5080785A1/es unknown
- 1999-06-08 OA OA1200000335A patent/OA11564A/en unknown
- 1999-06-08 ID IDW20010061A patent/ID27845A/id unknown
- 1999-06-08 HU HU0102767A patent/HUP0102767A3/hu unknown
- 1999-06-08 HR HR20000845A patent/HRP20000845A2/hr not_active Application Discontinuation
- 1999-06-08 CZ CZ20004587A patent/CZ293605B6/cs not_active IP Right Cessation
- 1999-06-08 DE DE69926632T patent/DE69926632T2/de not_active Expired - Lifetime
- 1999-06-08 AR ARP990102714A patent/AR018632A1/es active IP Right Grant
- 1999-06-08 US US09/719,188 patent/US6362199B1/en not_active Expired - Fee Related
- 1999-06-08 CA CA002334727A patent/CA2334727C/en not_active Expired - Fee Related
- 1999-06-08 KR KR1020007013994A patent/KR100586762B1/ko not_active Expired - Fee Related
- 1999-06-08 PE PE1999000511A patent/PE20000724A1/es not_active Application Discontinuation
- 1999-06-08 NZ NZ508638A patent/NZ508638A/en not_active IP Right Cessation
- 1999-06-08 AU AU45092/99A patent/AU753867B2/en not_active Ceased
- 1999-06-08 AT AT99927911T patent/ATE301650T1/de active
- 1999-06-08 DK DK99927911T patent/DK1086093T3/da active
- 1999-06-08 PL PL344694A patent/PL197160B1/pl not_active IP Right Cessation
- 1999-06-08 EA EA200001165A patent/EA003276B1/ru not_active IP Right Cessation
- 1999-06-08 CN CNB998094145A patent/CN1173970C/zh not_active Expired - Fee Related
- 1999-06-08 ES ES99927911T patent/ES2249010T3/es not_active Expired - Lifetime
- 1999-06-08 BR BR9911145-4A patent/BR9911145A/pt not_active Application Discontinuation
- 1999-06-08 EP EP99927911A patent/EP1086093B1/en not_active Expired - Lifetime
- 1999-06-08 JP JP2000553420A patent/JP2002517492A/ja active Pending
- 1999-06-08 AP APAP/P/2000/002008A patent/AP2000002008A0/en unknown
- 1999-06-08 IL IL14006299A patent/IL140062A0/xx active IP Right Grant
- 1999-06-17 TW TW088110159A patent/TWI229079B/zh not_active IP Right Cessation
-
2000
- 2000-11-30 IS IS5746A patent/IS5746A/is unknown
- 2000-12-04 IL IL140062A patent/IL140062A/en not_active IP Right Cessation
- 2000-12-07 NO NO20006227A patent/NO321904B1/no not_active IP Right Cessation
-
2001
- 2001-01-08 BG BG105123A patent/BG105123A/xx unknown
- 2001-11-16 US US09/990,513 patent/US6413985B1/en not_active Expired - Fee Related
-
2002
- 2002-05-14 US US10/145,258 patent/US6495566B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL143782A0 (en) | Quinoline derivatives | |
| AP2001002041A0 (en) | Quinoline derivatives | |
| PL343420A1 (en) | Quinoline derivatives | |
| HRP20010454B1 (en) | 1,2-annelated quinoline derivatives | |
| IL141226A0 (en) | 1h-imidazopyridine derivatives | |
| AP2001002040A0 (en) | Quinoline derivatives | |
| PL345540A1 (en) | Thiobenzimidazole derivatives | |
| IL128027A0 (en) | Benzosulfone derivatives | |
| GB9910384D0 (en) | Alpha-ketoamide derivatives | |
| IL128141A0 (en) | Tetrahydroquinoline derivatives as eaa antagonists | |
| IL137329A0 (en) | Vla-4 antagonists | |
| IL140062A0 (en) | Tetrahydroquinoline derivatives as glycine antagonists | |
| EG23802A (en) | 2-Phenylpyran-4-one derivatives | |
| GB9815505D0 (en) | Polypeptide derivatives | |
| GB9827729D0 (en) | Thieno-indole derivatives | |
| SI1086093T1 (sl) | Derivati tetrahidrokinolina kot antagonisti glicina | |
| IL139276A0 (en) | Cyclohexenondioxthio chromanoyl derivatives | |
| GB9922577D0 (en) | Substituted phosphinate based peptide derivatives | |
| GB9711030D0 (en) | Quinoline leukrotriene antagonists | |
| PL341899A1 (en) | Vla-4 antagonists | |
| GB9808696D0 (en) | Peptide derivatives | |
| GB9816279D0 (en) | Arylthiazolidinedione derivatives | |
| SI1051395T1 (sl) | N-hidroksiformamidni derivati |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |