IL136835A - Use of alkyl hydrogen fumarates for treating psoriasis, psoriatic arthritis, neurodermatitis and enteritis regionalis crohn - Google Patents

Use of alkyl hydrogen fumarates for treating psoriasis, psoriatic arthritis, neurodermatitis and enteritis regionalis crohn

Info

Publication number
IL136835A
IL136835A IL13683598A IL13683598A IL136835A IL 136835 A IL136835 A IL 136835A IL 13683598 A IL13683598 A IL 13683598A IL 13683598 A IL13683598 A IL 13683598A IL 136835 A IL136835 A IL 136835A
Authority
IL
Israel
Prior art keywords
neurodermatitis
psoriatic arthritis
treating psoriasis
alkyl hydrogen
hydrogen fumarates
Prior art date
Application number
IL13683598A
Other languages
English (en)
Other versions
IL136835A0 (en
Original Assignee
Fumapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fumapharm Ag filed Critical Fumapharm Ag
Publication of IL136835A0 publication Critical patent/IL136835A0/xx
Publication of IL136835A publication Critical patent/IL136835A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IL13683598A 1998-03-31 1998-12-08 Use of alkyl hydrogen fumarates for treating psoriasis, psoriatic arthritis, neurodermatitis and enteritis regionalis crohn IL136835A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19814358A DE19814358C2 (de) 1998-03-31 1998-03-31 Verwendung von Alkylhydrogenfumaraten zur Behandlung von Psoriasis, psoriatischer Arthritis, Neurodermitis und Enteritis regionalis Crohn
PCT/EP1998/007956 WO1999049858A1 (de) 1998-03-31 1998-12-08 Verwendung von alkylhydrogenfumaraten zur behandlung von psoriasis, psoriatischer arthritis, neurodermitis und enteritis regionalis crohn

Publications (2)

Publication Number Publication Date
IL136835A0 IL136835A0 (en) 2001-06-14
IL136835A true IL136835A (en) 2005-05-17

Family

ID=7863089

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13683598A IL136835A (en) 1998-03-31 1998-12-08 Use of alkyl hydrogen fumarates for treating psoriasis, psoriatic arthritis, neurodermatitis and enteritis regionalis crohn

Country Status (26)

Country Link
US (1) US6277882B1 (no)
EP (1) EP1059920B1 (no)
JP (1) JP3527890B2 (no)
CN (1) CN1150898C (no)
AT (1) ATE219936T1 (no)
AU (1) AU745281B2 (no)
BG (1) BG64744B1 (no)
BR (1) BRPI9815772B8 (no)
CA (1) CA2283915C (no)
CZ (1) CZ291788B6 (no)
DE (2) DE19814358C2 (no)
DK (1) DK1059920T3 (no)
EE (1) EE04702B1 (no)
ES (1) ES2179551T3 (no)
HK (1) HK1035134A1 (no)
HU (1) HU228848B1 (no)
IL (1) IL136835A (no)
NO (1) NO327750B1 (no)
NZ (1) NZ505341A (no)
PL (1) PL191803B1 (no)
PT (1) PT1059920E (no)
RS (1) RS49658B (no)
RU (1) RU2197233C2 (no)
SK (1) SK285187B6 (no)
TR (1) TR200001829T2 (no)
WO (1) WO1999049858A1 (no)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19839566C2 (de) * 1998-08-31 2002-01-17 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten in der Transplantationsmedizin
DE19853487A1 (de) * 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
CA2425599C (en) * 2001-01-12 2012-04-24 Fumapharm Ag Fumaric acid amides
DE10101307A1 (de) * 2001-01-12 2002-08-01 Fumapharm Ag Muri Fumarsäurederivate als NF-kappaB-Inhibitor
DE10217314A1 (de) * 2002-04-18 2003-11-13 Fumapharm Ag Muri Carbocyclische und Oxacarboncyclische Fumarsäure-Oligomere
WO2005023241A1 (en) * 2003-09-09 2005-03-17 Fumapharm Ag The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
DE10360869A1 (de) * 2003-09-09 2005-04-07 Fumapharm Ag Verwendung von Fumarsäurederivaten zur Therapie der Herzinsuffizienz, der Hyperkeratose und von Asthma
DE14172396T1 (de) 2004-10-08 2015-01-08 Forward Pharma A/S Gesteuerte Freisetzung von pharmazeutischen Zusammensetzungen mit Fumarinsäureester
US20080004344A1 (en) * 2004-11-10 2008-01-03 Aditech Pharma Ab Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use
WO2007006307A2 (en) * 2005-07-07 2007-01-18 Aditech Pharma Ab Novel salts of fumaric acid monoalkylesters and their pharmaceutical use
DE602006011910D1 (de) * 2005-07-07 2010-03-11 Aditech Pharma Ag Neue glucopyranoseester und glucofuranoseester von fumarsäurealkylestern und deren pharmazeutische verwendung
WO2007042035A2 (en) * 2005-10-07 2007-04-19 Aditech Pharma Ab Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders
EP1951206A1 (en) * 2005-10-07 2008-08-06 Aditech Pharma AB Controlled release pharmaceutical compositions comprising a fumaric acid ester
PL2653873T3 (pl) 2007-02-08 2022-08-22 Biogen Idec Ma Inc. Kompozycje i zastosowania do leczenia stwardnienia rozsianego
EP2139467B1 (en) * 2007-02-08 2016-09-21 Biogen MA Inc. Neuroprotection in demyelinating diseases
PL2334378T3 (pl) * 2008-08-19 2014-09-30 Xenoport Inc Proleki wodorofumaranu metylu, ich kompozycje farmaceutyczne i sposoby zastosowania
CN109044985A (zh) 2009-01-09 2018-12-21 前进制药知识产权有限公司 包含溶蚀骨架中的一种或多种富马酸酯的药物制剂
DK2718257T3 (en) 2011-06-08 2018-02-12 Biogen Ma Inc PROCEDURE FOR THE PREPARATION OF HIGH PURITY Crystalline DIMETHYL FUMARATE
WO2013076216A1 (en) 2011-11-24 2013-05-30 Synthon Bv Controlled release particles comprising dimethyl fumarate
US9504679B2 (en) 2011-12-19 2016-11-29 Bjoern Colin Kahrs Pharmaceutical compositions comprising glitazones and Nrf2 activators
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
CA2864040A1 (en) 2012-02-07 2013-08-15 Xenoport, Inc. Morpholinoalkyl fumarate compounds, pharmaceutical compositions, and methods of use
CN114146081A (zh) * 2012-02-07 2022-03-08 比奥根玛公司 含有富马酸二甲酯的药物组合物
KR101449114B1 (ko) * 2012-08-21 2014-10-13 바이오스펙트럼 주식회사 푸마르산을 유효성분으로 포함하는 항염 조성물
AU2013305684B2 (en) 2012-08-22 2016-11-24 Xenoport, Inc. Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof
US10945984B2 (en) 2012-08-22 2021-03-16 Arbor Pharmaceuticals, Llc Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects
US20140171504A1 (en) 2012-12-14 2014-06-19 Georgia Regents Research Institute, Inc. Methods of Treating Sickle Cell Disease and Related Disorders Using Fumaric Acid Esters
WO2014100728A1 (en) 2012-12-21 2014-06-26 Biogen Idec Ma Inc. Deuterium substituted fumarate derivatives
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
ES2955137T3 (es) 2013-03-14 2023-11-28 Alkermes Pharma Ireland Ltd Profármacos de fumaratos y su uso en el tratamiento de diversas enfermedades
US10179118B2 (en) 2013-03-24 2019-01-15 Arbor Pharmaceuticals, Llc Pharmaceutical compositions of dimethyl fumarate
WO2014197860A1 (en) 2013-06-07 2014-12-11 Xenoport, Inc. Method of making monomethyl fumarate
WO2014205392A1 (en) 2013-06-21 2014-12-24 Xenoport, Inc. Cocrystals of dimethyl fumarate
JP2016528302A (ja) 2013-08-26 2016-09-15 フォーワード・ファルマ・アクティーゼルスカブＦｏｒｗａｒｄ Ｐｈａｒｍａ Ａ／Ｓ 低１日用量で投与するためのフマル酸ジメチルを含む医薬組成物
JP2016534133A (ja) 2013-09-06 2016-11-04 ゼノポート，インコーポレイティド （ｎ，ｎ−ジエチルカルバモイル）メチル メチル（２ｅ）ブト−２−エン−１，４−ジオエートの結晶形態、その合成方法及び使用
US20150079180A1 (en) 2013-09-18 2015-03-19 Xenoport, Inc. Nanoparticle compositions of dimethyl fumarate
NZ723269A (en) 2014-02-24 2017-04-28 Alkermes Pharma Ireland Ltd Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
US9999672B2 (en) 2014-03-24 2018-06-19 Xenoport, Inc. Pharmaceutical compositions of fumaric acid esters
EP3777863A1 (en) * 2014-09-12 2021-02-17 Tobira Therapeutics, Inc. Cenicriviroc combination therapy for the treatment of fibrosis
WO2016061393A1 (en) 2014-10-15 2016-04-21 Xenoport, Inc. Fumarate compounds, pharmaceutical compositions, and methods of use
EP3253377B1 (en) 2015-02-08 2021-05-12 Alkermes Pharma Ireland Limited Monomethylfumarate prodrug compositions
DK3273951T3 (da) 2015-03-27 2020-11-02 Symbionyx Pharmaceuticals Inc Sammensætninger og fremgangsmåder til behandling af psoriasis
WO2017060400A1 (en) 2015-10-07 2017-04-13 Neurovive Pharmaceutical Ab Protected carboxylic acid-based metabolites for the treatment of disesases related to mitochondrial dysfunctions
CN105496804A (zh) * 2015-12-25 2016-04-20 知识产权全资有限公司 用于处理头发以及治疗头部牛皮藓的配方及其试剂盒和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2530372A1 (de) * 1975-07-08 1977-01-13 Walter Dr Schweckendiek Pharmazeutische zubereitungen zur behandlung von psoriasis
DE2621214C3 (de) * 1976-05-13 1981-11-12 Koronis Gmbh Chemisch-Pharmazeutische Praeparate, 5441 Sassen Verwendung von Stabilisatoren in Arzneimitteln mit Fumarsäuremonoäthylester und desen Mineralsalzen
DE3127432A1 (de) * 1981-07-11 1983-02-03 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von fumarsaeuremonoester
US5242905A (en) * 1987-09-04 1993-09-07 Dexter Chemical Corporation Pharmaceutical compositions for the treatment of psoriasis
US5214196A (en) * 1987-09-04 1993-05-25 Dexter Chemical Corporation Diethyl ester of di-glycyl fumaramide
US4959389A (en) 1987-10-19 1990-09-25 Speiser Peter P Pharmaceutical preparation for the treatment of psoriatic arthritis
US5424332A (en) * 1987-10-19 1995-06-13 Speiser; Peter P. Pharmaceutical composition and process for the production thereof
DE8714143U1 (no) * 1987-10-23 1988-03-24 Werler Kunststoffwerke Gmbh & Co, 4760 Werl, De
DE3834794A1 (de) * 1988-10-12 1990-04-19 F Schielein Oral zu verabreichendes mittel zur behandlung von psoriasis
WO1992012952A1 (en) * 1991-01-18 1992-08-06 Dexter Chemical Corporation Malic acid derivatives and compositions for the treatment of psoriasis
US5407772A (en) * 1993-11-30 1995-04-18 Xerox Corporation Unsaturated polyesters
US5972363A (en) * 1997-04-11 1999-10-26 Rohm And Haas Company Use of an encapsulated bioactive composition

Also Published As

Publication number Publication date
CZ291788B6 (cs) 2003-05-14
BRPI9815772B1 (pt) 2016-02-10
TR200001829T2 (tr) 2000-11-21
HUP0103234A2 (hu) 2002-01-28
NO20002872D0 (no) 2000-06-06
DE19814358A1 (de) 1999-10-07
JP3527890B2 (ja) 2004-05-17
DK1059920T3 (da) 2002-10-14
BG104566A (en) 2001-01-31
RU2197233C2 (ru) 2003-01-27
WO1999049858A1 (de) 1999-10-07
JP2002509883A (ja) 2002-04-02
IL136835A0 (en) 2001-06-14
CZ20003086A3 (cs) 2000-11-15
US6277882B1 (en) 2001-08-21
NZ505341A (en) 2002-04-26
BG64744B1 (bg) 2006-02-28
HUP0103234A3 (en) 2003-11-28
NO327750B1 (no) 2009-09-14
HK1035134A1 (en) 2001-11-16
EE200000440A (et) 2001-12-17
PL341240A1 (en) 2001-03-26
CN1150898C (zh) 2004-05-26
CA2283915A1 (en) 1999-09-30
DE19814358C2 (de) 2002-01-17
RS49658B (sr) 2007-09-21
BRPI9815772B8 (pt) 2021-07-06
CA2283915C (en) 2002-12-03
DE59804704D1 (de) 2002-08-08
SK285187B6 (sk) 2006-08-03
BRPI9815772A (pt) 2000-11-21
AU745281B2 (en) 2002-03-21
EE04702B1 (et) 2006-10-16
EP1059920A1 (de) 2000-12-20
AU2159399A (en) 1999-10-18
HU228848B1 (en) 2013-06-28
NO20002872L (no) 2000-06-06
ATE219936T1 (de) 2002-07-15
SK7922000A3 (en) 2001-01-18
EP1059920B1 (de) 2002-07-03
PT1059920E (pt) 2002-11-29
ES2179551T3 (es) 2003-01-16
CN1284870A (zh) 2001-02-21
YU32000A (sh) 2002-03-18
PL191803B1 (pl) 2006-07-31

Similar Documents

Publication Publication Date Title
IL136835A (en) Use of alkyl hydrogen fumarates for treating psoriasis, psoriatic arthritis, neurodermatitis and enteritis regionalis crohn
IL140891A (en) Fumaric acid microtablets
ITTV930017A1 (it) Struttura di contenitore, particolarmente per le colture cellulari
GB2318055A (en) Dosage form comprising oxybutynin
HRP940370B1 (en) New sulfonylaminopyrimidines
SG43005A1 (en) Transistor with common base region
IE850111L (en) Pharmaceutical composition
CA2100836C (en) PHARMACEUTICAL COMPOSITION
ES2107260T3 (es) Procedimiento para la metilacion de compuestos organicos.
SI1059920T1 (en) Use of alkyl hydrogen fumarates for treating psoriasis, psoriatic arthritis, neurodermatitis and regional enteritis
IL60973A0 (en) Anaerobic thermophilic microorganism culture
ES1038713U (es) Nuevo estuche porta-fotos.
GB9425540D0 (en) Cell culture vessels
GB9325882D0 (en) Cell culture vessels
ES1028694U (es) Chaleco salvavidas.
GB9324994D0 (en) Culture vessel
NO902039D0 (no) Fremgangsmaate ved dyrking av cellekulturer i bioreaktor.

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees