IL136100A - Biphenylamidine derivatives and pharmaceutical compositions containing the same - Google Patents
Biphenylamidine derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL136100A IL136100A IL13610098A IL13610098A IL136100A IL 136100 A IL136100 A IL 136100A IL 13610098 A IL13610098 A IL 13610098A IL 13610098 A IL13610098 A IL 13610098A IL 136100 A IL136100 A IL 136100A
- Authority
- IL
- Israel
- Prior art keywords
- same
- pharmaceutical compositions
- compositions containing
- biphenylamidine derivatives
- biphenylamidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/18—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP31969897 | 1997-11-20 | ||
JP12749898 | 1998-05-11 | ||
PCT/JP1998/005209 WO1999026918A1 (fr) | 1997-11-20 | 1998-11-19 | Derives de biphenylamidine |
Publications (2)
Publication Number | Publication Date |
---|---|
IL136100A0 IL136100A0 (en) | 2001-05-20 |
IL136100A true IL136100A (en) | 2005-05-17 |
Family
ID=26463455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13610098A IL136100A (en) | 1997-11-20 | 1998-11-19 | Biphenylamidine derivatives and pharmaceutical compositions containing the same |
Country Status (28)
Country | Link |
---|---|
US (1) | US6706745B1 (uk) |
EP (1) | EP1043310B1 (uk) |
KR (1) | KR100581506B1 (uk) |
CN (1) | CN1150162C (uk) |
AT (1) | ATE268751T1 (uk) |
AU (1) | AU744567B2 (uk) |
BG (1) | BG63536B1 (uk) |
BR (1) | BR9814983A (uk) |
CA (1) | CA2310331A1 (uk) |
DE (1) | DE69824450T2 (uk) |
DK (1) | DK1043310T3 (uk) |
EE (1) | EE04564B1 (uk) |
ES (1) | ES2218866T3 (uk) |
HR (1) | HRP20000304B1 (uk) |
HU (1) | HUP0100085A3 (uk) |
ID (1) | ID24846A (uk) |
IL (1) | IL136100A (uk) |
IS (1) | IS5497A (uk) |
NO (1) | NO20002589L (uk) |
NZ (1) | NZ504407A (uk) |
PL (1) | PL340658A1 (uk) |
PT (1) | PT1043310E (uk) |
RU (1) | RU2197478C2 (uk) |
SK (1) | SK7612000A3 (uk) |
TR (1) | TR200001452T2 (uk) |
TW (1) | TW523504B (uk) |
UA (1) | UA52797C2 (uk) |
WO (1) | WO1999026918A1 (uk) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010032175A (ko) * | 1997-11-20 | 2001-04-16 | 야스이 쇼사꾸 | 비페닐아미딘 유도체 |
CA2360686A1 (en) * | 1999-01-28 | 2000-08-03 | Teijin Limited | Release-regulating preparations |
AU4614100A (en) * | 1999-05-17 | 2000-12-05 | Teijin Limited | Cyanobiphenyl derivatives |
WO2001056989A2 (en) * | 2000-02-01 | 2001-08-09 | Cor Therapeutics, Inc. | Inhibitors of factor xa |
US6316475B1 (en) * | 2000-11-17 | 2001-11-13 | Abbott Laboratories | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications |
CN1610665A (zh) * | 2001-01-26 | 2005-04-27 | 帝人株式会社 | 氰基苯基苯甲酸衍生物的制备方法 |
EP1357108A4 (en) * | 2001-01-29 | 2005-12-07 | Teijin Ltd | BENZAMIDINE DERIVATIVES AND PROCESS FOR PRODUCING SUCH DERIVATIVES |
AR035425A1 (es) * | 2001-01-30 | 2004-05-26 | Teijin Ltd | Cristal de diclorhidrato del acido 3-(3-amidinofenil)-5-[({[1-(iminoetil)-4-piperidil]metil}amino)metil]benzoico y proceso para prepararlo |
CA2436373A1 (en) * | 2001-01-30 | 2002-08-08 | Teijin Limited | Pharmaceutical composition |
EP1443041A4 (en) * | 2001-11-09 | 2006-06-07 | Kissei Pharmaceutical | 5-AMIDINO-2-HYDROXYBENZENE-SULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THEM, THEIR MEDICAL USE AND INTERMEDIATE PRODUCTS USED IN THEIR PRODUCTION |
CA2468942A1 (en) | 2001-11-30 | 2003-06-12 | Teijin Limited | Process for producing 5-(3-cyanophenyl)-3-formylbenzoic acid compound |
DK1569912T3 (en) | 2002-12-03 | 2015-06-29 | Pharmacyclics Inc | 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors. |
CN101291656B (zh) | 2005-08-18 | 2012-11-07 | 帝人制药株式会社 | 具有准确的用量分割功能的制剂 |
EP1915988A4 (en) | 2005-08-18 | 2012-07-25 | Teijin Pharma Ltd | COMPRESSOR COMPRISING MULTIPLE SEGMENTS CONTAINING MEDICAMENTS |
PE20070698A1 (es) | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
US10464896B2 (en) | 2015-06-11 | 2019-11-05 | Basilea Pharmaceutica International AG | Efflux-pump inhibitors and therapeutic uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4102024A1 (de) | 1991-01-24 | 1992-07-30 | Thomae Gmbh Dr K | Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
DK0567967T3 (da) | 1992-04-28 | 1996-11-18 | Thomae Gmbh Dr K | Tritium-mærkede fibrinogen-receptor-antagonister, deres anvendelse og fremgangsmåde til deres fremstilling |
DE4219158A1 (de) * | 1992-06-11 | 1993-12-16 | Thomae Gmbh Dr K | Biphenylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
JPH101467A (ja) * | 1996-06-13 | 1998-01-06 | Banyu Pharmaceut Co Ltd | ビフェニルアミジン誘導体 |
KR20010032175A (ko) | 1997-11-20 | 2001-04-16 | 야스이 쇼사꾸 | 비페닐아미딘 유도체 |
-
1998
- 1998-11-19 ES ES98954747T patent/ES2218866T3/es not_active Expired - Lifetime
- 1998-11-19 TR TR2000/01452T patent/TR200001452T2/xx unknown
- 1998-11-19 EE EEP200000298A patent/EE04564B1/xx not_active IP Right Cessation
- 1998-11-19 DK DK98954747T patent/DK1043310T3/da active
- 1998-11-19 WO PCT/JP1998/005209 patent/WO1999026918A1/ja active IP Right Grant
- 1998-11-19 DE DE69824450T patent/DE69824450T2/de not_active Expired - Fee Related
- 1998-11-19 TW TW087119208A patent/TW523504B/zh not_active IP Right Cessation
- 1998-11-19 RU RU2000115947/04A patent/RU2197478C2/ru not_active IP Right Cessation
- 1998-11-19 SK SK761-2000A patent/SK7612000A3/sk unknown
- 1998-11-19 EP EP98954747A patent/EP1043310B1/en not_active Expired - Lifetime
- 1998-11-19 NZ NZ504407A patent/NZ504407A/en unknown
- 1998-11-19 UA UA2000063535A patent/UA52797C2/uk unknown
- 1998-11-19 AU AU11740/99A patent/AU744567B2/en not_active Ceased
- 1998-11-19 CA CA002310331A patent/CA2310331A1/en not_active Abandoned
- 1998-11-19 ID IDW20000955A patent/ID24846A/id unknown
- 1998-11-19 KR KR1020007005463A patent/KR100581506B1/ko not_active IP Right Cessation
- 1998-11-19 BR BR9814983-0A patent/BR9814983A/pt not_active Application Discontinuation
- 1998-11-19 CN CNB988132206A patent/CN1150162C/zh not_active Expired - Fee Related
- 1998-11-19 AT AT98954747T patent/ATE268751T1/de not_active IP Right Cessation
- 1998-11-19 PT PT98954747T patent/PT1043310E/pt unknown
- 1998-11-19 HU HU0100085A patent/HUP0100085A3/hu unknown
- 1998-11-19 PL PL98340658A patent/PL340658A1/xx not_active Application Discontinuation
- 1998-11-19 US US09/554,799 patent/US6706745B1/en not_active Expired - Fee Related
- 1998-11-19 IL IL13610098A patent/IL136100A/xx not_active IP Right Cessation
-
2000
- 2000-05-15 IS IS5497A patent/IS5497A/is unknown
- 2000-05-16 HR HR20000304A patent/HRP20000304B1/xx not_active IP Right Cessation
- 2000-05-17 BG BG104447A patent/BG63536B1/bg unknown
- 2000-05-19 NO NO20002589A patent/NO20002589L/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HU9500240D0 (en) | New prolin-amide derivatives and pharmaceutical compositions containing them as active component | |
ATE260255T1 (de) | 5-oxo-pyrrolidine-2-carbonsäure- hydroxamidderivate | |
DE69831868D1 (en) | Antithrombosemittel | |
IL133623A0 (en) | Antithrombotic agents | |
AU699008B2 (en) | Aminothiazole derivative, medicament containing the same, and intermediate for preperation of said compound | |
IL136100A (en) | Biphenylamidine derivatives and pharmaceutical compositions containing the same | |
IL143545A0 (en) | Thrombin inhibitors | |
AU7517400A (en) | N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent | |
PL309874A1 (en) | Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives | |
AU3583989A (en) | New cephem compounds and processes for preparation thereof | |
IL125982A0 (en) | 2-(arylphenyl) amino-imidazoline derivatives | |
MY129094A (en) | Condensed polycyclic compounds | |
CA2245484A1 (en) | Novel urea derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |