IL133366A - 4-Phenylpiperidine compounds, process for their preparation and uses thereof - Google Patents

4-Phenylpiperidine compounds, process for their preparation and uses thereof

Info

Publication number
IL133366A
IL133366A IL13336697A IL13336697A IL133366A IL 133366 A IL133366 A IL 133366A IL 13336697 A IL13336697 A IL 13336697A IL 13336697 A IL13336697 A IL 13336697A IL 133366 A IL133366 A IL 133366A
Authority
IL
Israel
Prior art keywords
alkyl
preparation
phenylpiperidine compounds
halo
alkoxy
Prior art date
Application number
IL13336697A
Other languages
English (en)
Other versions
IL133366A0 (en
Inventor
Franciscus Bernardus Benneker
Frans Van Dalen
Jacobus Maria Lemmens
Theodorus Hendricus Ant Peters
Frantisek Picha
Original Assignee
Synthon Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26647319&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL133366(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthon Bv filed Critical Synthon Bv
Publication of IL133366A0 publication Critical patent/IL133366A0/xx
Publication of IL133366A publication Critical patent/IL133366A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
IL13336697A 1997-06-10 1997-06-10 4-Phenylpiperidine compounds, process for their preparation and uses thereof IL133366A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/NL1997/000328 WO1998056787A1 (en) 1997-06-10 1997-06-10 4-Phenylpiperidine compounds
US08/872,023 US5874447A (en) 1997-06-10 1997-06-10 4-Phenylpiperidine compounds for treating depression

Publications (2)

Publication Number Publication Date
IL133366A0 IL133366A0 (en) 2001-04-30
IL133366A true IL133366A (en) 2005-11-20

Family

ID=26647319

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13336697A IL133366A (en) 1997-06-10 1997-06-10 4-Phenylpiperidine compounds, process for their preparation and uses thereof

Country Status (26)

Country Link
US (4) US5874447A (no)
EP (2) EP1078925A1 (no)
JP (1) JP2002503248A (no)
KR (1) KR100543614B1 (no)
AT (1) ATE200781T1 (no)
AU (1) AU3108097A (no)
BG (1) BG64315B1 (no)
BR (1) BR9714787A (no)
CA (1) CA2293247C (no)
CZ (1) CZ295301B6 (no)
DE (2) DE29724281U1 (no)
DK (1) DK0994872T3 (no)
EE (2) EE200200633A (no)
ES (1) ES2155995T3 (no)
GR (1) GR3035784T3 (no)
HK (1) HK1027352A1 (no)
HU (1) HUP0003141A3 (no)
IL (1) IL133366A (no)
IS (2) IS1927B (no)
NO (3) NO317371B1 (no)
PL (1) PL188450B1 (no)
PT (1) PT994872E (no)
SI (1) SI0994872T1 (no)
SK (1) SK283394B6 (no)
TR (2) TR200201156T2 (no)
WO (1) WO1998056787A1 (no)

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AP2000001950A0 (en) * 1998-04-09 2000-12-31 Smithkline Beecham Plc Paroxetine maleate.
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CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
GB9814316D0 (en) * 1998-07-02 1998-09-02 Smithkline Beecham Plc Novel compounds
US20010023252A1 (en) * 1998-07-02 2001-09-20 Smithkline Beecham Plc Novel compound
WO2000008016A1 (en) * 1998-08-08 2000-02-17 Smithkline Beecham Plc Paroxetine salts
GB9827431D0 (en) * 1998-12-11 1999-02-03 Smithkline Beecham Plc Novel compound
GB9828781D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
GB9828779D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
GB9828780D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
ES2159260B1 (es) * 1999-06-22 2002-05-01 Smithkline Beechan Plc Nueva composicion de metanosulfonato de paroxetina
WO2000078290A2 (en) * 1999-06-22 2000-12-28 Smithkline Beecham P.L.C. Pharmaceutical composition comprising a salt of paroxetine
GB9914585D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
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GB9919052D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel compound composition and process
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IL154422A0 (en) * 2000-08-28 2003-09-17 Synthon Bv Paroxetine compositions and processes for making the same
JPWO2002022609A1 (ja) * 2000-09-14 2004-01-22 旭硝子株式会社 実質的に有機溶媒を含まないパロキセチン塩類の製造方法
DE20100529U1 (de) * 2001-01-11 2001-05-10 Synthon Bv Pharmazeutische Tablette umfassend Paroxetinmesylat
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Also Published As

Publication number Publication date
IL133366A0 (en) 2001-04-30
EP0994872B1 (en) 2001-04-25
EP0994872A1 (en) 2000-04-26
US20090326233A1 (en) 2009-12-31
SK283394B6 (sk) 2003-07-01
PT994872E (pt) 2001-09-28
CZ429599A3 (cs) 2000-04-12
CA2293247C (en) 2005-04-12
TR200201156T2 (tr) 2002-07-22
CZ295301B6 (cs) 2005-07-13
EE9900570A (et) 2000-08-15
HUP0003141A2 (en) 2001-03-28
IS1927B (is) 2004-04-15
EE03970B1 (et) 2003-02-17
WO1998056787A1 (en) 1998-12-17
DE69704679D1 (de) 2001-05-31
DK0994872T3 (da) 2001-05-28
EE200200633A (et) 2003-02-17
US6900327B2 (en) 2005-05-31
EP0994872B9 (en) 2001-12-05
NO20033765L (no) 2000-02-09
IS5249A (is) 1999-11-16
US7598271B1 (en) 2009-10-06
CA2293247A1 (en) 1998-12-17
NO995455D0 (no) 1999-11-08
DE29724281U1 (de) 2000-08-10
BG103980A (en) 2000-07-31
HUP0003141A3 (en) 2001-04-28
PL188450B1 (pl) 2005-02-28
DE69704679T2 (de) 2001-09-13
TR199903025T2 (xx) 2000-07-21
BG64315B1 (bg) 2004-09-30
JP2002503248A (ja) 2002-01-29
EP1078925A1 (en) 2001-02-28
BR9714787A (pt) 2000-07-18
SI0994872T1 (no) 2001-08-31
NO20033766L (no) 2000-02-09
ATE200781T1 (de) 2001-05-15
KR100543614B1 (ko) 2006-01-20
SK161999A3 (en) 2000-08-14
AU3108097A (en) 1998-12-30
GR3035784T3 (en) 2001-07-31
PL336895A1 (en) 2000-07-17
KR20010013615A (ko) 2001-02-26
NO20033766D0 (no) 2003-08-25
US20010031767A1 (en) 2001-10-18
HK1027352A1 (en) 2001-01-12
IS7098A (is) 2004-01-08
NO20033765D0 (no) 2003-08-25
NO317371B1 (no) 2004-10-18
ES2155995T3 (es) 2001-06-01
US5874447A (en) 1999-02-23
NO995455L (no) 2000-02-09

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