IL127979A0 - Diagnosis and treatment of cancer - Google Patents
Diagnosis and treatment of cancerInfo
- Publication number
- IL127979A0 IL127979A0 IL12797997A IL12797997A IL127979A0 IL 127979 A0 IL127979 A0 IL 127979A0 IL 12797997 A IL12797997 A IL 12797997A IL 12797997 A IL12797997 A IL 12797997A IL 127979 A0 IL127979 A0 IL 127979A0
- Authority
- IL
- Israel
- Prior art keywords
- prostate
- specific membrane
- prostate specific
- cancerous
- biological agents
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2212596P | 1996-07-18 | 1996-07-18 | |
US08/838,682 US6107090A (en) | 1996-05-06 | 1997-04-09 | Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains |
PCT/US1997/012035 WO1998003873A1 (en) | 1996-07-18 | 1997-07-17 | Treatment and diagnosis of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
IL127979A0 true IL127979A0 (en) | 1999-11-30 |
Family
ID=26695548
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12797997A IL127979A0 (en) | 1996-07-18 | 1997-07-17 | Diagnosis and treatment of cancer |
IL162230A IL162230A (en) | 1996-07-18 | 2004-05-30 | Antibodies and antigen binding portions thereof that bind prostate specific membrane antigen (psma) |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL162230A IL162230A (en) | 1996-07-18 | 2004-05-30 | Antibodies and antigen binding portions thereof that bind prostate specific membrane antigen (psma) |
Country Status (16)
Country | Link |
---|---|
US (4) | US6107090A (xx) |
EP (2) | EP0956506B1 (xx) |
JP (2) | JP4503102B2 (xx) |
CN (2) | CN100344970C (xx) |
AT (1) | ATE319089T1 (xx) |
AU (1) | AU733544C (xx) |
BR (1) | BR9710487A (xx) |
CA (1) | CA2261018C (xx) |
DE (1) | DE69735368T2 (xx) |
EA (2) | EA200400179A1 (xx) |
ES (1) | ES2255723T3 (xx) |
HK (1) | HK1025631A1 (xx) |
IL (2) | IL127979A0 (xx) |
NZ (2) | NZ333683A (xx) |
PT (1) | PT956506E (xx) |
WO (1) | WO1998003873A1 (xx) |
Families Citing this family (143)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965132A (en) | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
US6749853B1 (en) | 1992-03-05 | 2004-06-15 | Board Of Regents, The University Of Texas System | Combined methods and compositions for coagulation and tumor treatment |
US7105159B1 (en) | 1992-11-05 | 2006-09-12 | Sloan-Kettering Institute For Cancer Research | Antibodies to prostate-specific membrane antigen |
US7070782B1 (en) | 1992-11-05 | 2006-07-04 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
US6953668B1 (en) | 1992-11-05 | 2005-10-11 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
US6569432B1 (en) * | 1995-02-24 | 2003-05-27 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
AU717937B2 (en) | 1995-02-24 | 2000-04-06 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
US20040253246A1 (en) * | 1996-02-23 | 2004-12-16 | Israeli Ron S. | Prostate-specific membrane antigen and uses thereof |
US6150508A (en) * | 1996-03-25 | 2000-11-21 | Northwest Biotherapeutics, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US7381407B1 (en) * | 1996-03-25 | 2008-06-03 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US6962981B1 (en) | 1996-03-25 | 2005-11-08 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US6136311A (en) * | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
US20060024301A1 (en) * | 1997-02-25 | 2006-02-02 | Corixa Corporation | Prostate-specific polypeptides and fusion polypeptides thereof |
US6759515B1 (en) * | 1997-02-25 | 2004-07-06 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
US20060269532A1 (en) * | 1997-02-25 | 2006-11-30 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
US6207805B1 (en) * | 1997-07-18 | 2001-03-27 | University Of Iowa Research Foundation | Prostate cell surface antigen-specific antibodies |
US6232287B1 (en) * | 1998-03-13 | 2001-05-15 | The Burnham Institute | Molecules that home to various selected organs or tissues |
US6200765B1 (en) | 1998-05-04 | 2001-03-13 | Pacific Northwest Cancer Foundation | Non-invasive methods to detect prostate cancer |
FR2791573B1 (fr) * | 1999-03-30 | 2003-04-11 | Pf Medicament | Utilisation d'un extrait de serenoa repens pour la fabrication d'un medicament destine au traitement du cancer de la prostate |
AU783356B2 (en) * | 1999-07-29 | 2005-10-20 | Medarex, Inc. | Human monoclonal antibodies to prostate specific membrane antigen |
EP1710256A1 (en) * | 1999-07-29 | 2006-10-11 | Medarex, Inc. | Human monoclonal antibodies to prostate specific membrane antigen |
WO2001019956A2 (en) * | 1999-09-13 | 2001-03-22 | Bander Neil H | A method for isolation of prostatic epithelial cells from semen |
US20080153119A1 (en) * | 1999-09-24 | 2008-06-26 | Schebo Biotech Ag | Detecting the presence of pyruvate kinase isoenzyme in feces |
AU3679801A (en) | 2000-02-08 | 2001-08-20 | Rice University | Optically-active nanoparticles for use in therapeutic and diagnostic methods |
US6379550B1 (en) * | 2000-07-24 | 2002-04-30 | Health Research, Inc. | Method for detecting PSA and its molecular forms using thiophilic gel |
US7048931B1 (en) | 2000-11-09 | 2006-05-23 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
US7468354B2 (en) | 2000-12-01 | 2008-12-23 | Genspera, Inc. | Tissue specific prodrugs |
WO2002096460A1 (en) * | 2001-05-30 | 2002-12-05 | Cornell Research Foundation, Inc. | Endopeptidase/anti-psma antibody fusion proteins for treatment of cancer |
JP4619651B2 (ja) * | 2001-06-01 | 2011-01-26 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 前立腺特異的膜抗原に対する修飾抗体およびその使用 |
US7666414B2 (en) * | 2001-06-01 | 2010-02-23 | Cornell Research Foundation, Inc. | Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen |
US7514078B2 (en) * | 2001-06-01 | 2009-04-07 | Cornell Research Foundation, Inc. | Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies |
US20060073530A1 (en) * | 2001-08-15 | 2006-04-06 | Olaf Schneewind | Methods and compositions involving sortase B |
AU2002359244A1 (en) * | 2001-09-05 | 2003-04-28 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of | Imaging the activity of extracellular proteases in cells using mutant anthrax toxin protective antigens that are cleaved by specific extracellular proteases |
CA2452288A1 (en) * | 2001-09-20 | 2003-03-27 | Cornell Research Foundation, Inc. | Methods and compositions for treating and preventing skin disorders using binding agents specific for psma |
US20030211075A1 (en) * | 2001-09-27 | 2003-11-13 | Thorpe Philip E. | Combined compositions for tumor vasculature coagulation and treatment |
US20040161776A1 (en) * | 2001-10-23 | 2004-08-19 | Maddon Paul J. | PSMA formulations and uses thereof |
CA2464239C (en) * | 2001-10-23 | 2016-07-12 | Psma Development Company, L.L.C. | Psma antibodies and protein multimers |
US20050215472A1 (en) * | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
US7767803B2 (en) * | 2002-06-18 | 2010-08-03 | Archemix Corp. | Stabilized aptamers to PSMA and their use as prostate cancer therapeutics |
NZ584715A (en) | 2002-07-15 | 2011-12-22 | Univ Texas | Peptides binding to phosphatidylethanolamine and their use in treating viral infections and cancer |
US7390898B2 (en) | 2002-08-02 | 2008-06-24 | Immunogen Inc. | Cytotoxic agents containing novel potent taxanes and their therapeutic use |
DE60323677D1 (de) * | 2003-01-10 | 2008-10-30 | Millennium Pharm Inc | Verfahren zur bestimmung des wiederauftretens von prostata krebs |
CA2514419A1 (en) * | 2003-01-28 | 2004-08-12 | Proscan Rx Pharma Inc. | Prostate cancer diagnosis and treatment |
WO2005094882A1 (en) * | 2004-03-03 | 2005-10-13 | Millennium Pharmaceuticals, Inc. | Modified antibodies to prostate-specific membrane antigen and uses thereof |
WO2005092286A2 (en) * | 2004-03-29 | 2005-10-06 | The University Of Houston System | Metallic nano-particles and discrete polymer-coated nano-particles |
US7910693B2 (en) * | 2004-04-19 | 2011-03-22 | Proscan Rx Pharma Inc. | Prostate cancer diagnosis and treatment |
JP2008519642A (ja) * | 2004-11-12 | 2008-06-12 | ケーピーイー リミテッド | ナノ粒子を介した超音波治療および診断影像法 |
WO2006086345A2 (en) * | 2005-02-07 | 2006-08-17 | The Trustees Of Columbia University In The City Of New York | Methods to treat or prevent hormone-resistant prostate cancer using sirna specific for protocadherin-pc, or other inhibitors of protocadherin-pc expression or activity |
US7875278B2 (en) * | 2005-02-18 | 2011-01-25 | Medarex, Inc. | Monoclonal antibodies against prostate specific membrane antigen (PSMA) lacking in fucosyl residues |
MX2007009878A (es) * | 2005-02-18 | 2007-10-03 | Medarex Inc | Anticuerpos monoclonales para antigeno de membrana especifica para prostata (amep). |
EP1863828A4 (en) * | 2005-03-07 | 2010-10-13 | Archemix Corp | STABILIZED APTAMERS FOR PSMA AND THEIR USE AS PROSTATE ACID THERAPEUTICS |
EP1726650A1 (en) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
US7736647B2 (en) * | 2005-06-15 | 2010-06-15 | Monoclonal Antibodies Therapeutics | Anti-CD71 monoclonal antibodies and uses thereof for treating malignant tumor cells |
CN103127523A (zh) * | 2005-06-20 | 2013-06-05 | Psma开发有限公司 | Psma抗体-药物缀合物 |
NZ566395A (en) * | 2005-09-26 | 2012-03-30 | Medarex Inc | Human monoclonal antibodies to CD70 |
PL1964852T3 (pl) * | 2005-12-20 | 2013-09-30 | Sbi Biotech Co Ltd | Przeciwciało anty-ilt7 |
MX2009000709A (es) * | 2006-07-18 | 2009-02-04 | Sanofi Aventis | Anticuerpo antagonista contra epha2 para el tratamiento de cancer. |
US20100150950A1 (en) * | 2006-12-14 | 2010-06-17 | Medarex, Inc. | Human antibodies that bind cd70 and uses thereof |
WO2009015263A2 (en) * | 2007-07-25 | 2009-01-29 | Wyeth | Methods for characterizing cell proximity |
JP5951929B2 (ja) | 2007-10-03 | 2016-07-13 | コーネル ユニヴァーシティー | Psma抗体を用いる増殖性障害の治療 |
US8602170B2 (en) | 2007-11-14 | 2013-12-10 | Inventio Ag | Multiple brake device for elevator with monitoring |
CA2721169A1 (en) * | 2008-04-14 | 2009-10-22 | Proscan Rx Pharma Inc. | Prostate specific membrane antigen antibodies and antigen binding fragments |
WO2010027513A2 (en) | 2008-09-08 | 2010-03-11 | Psma Development Company, Llc | Methods for killing psma-expressing, taxane-resistant cancer cells |
US20100082438A1 (en) * | 2008-10-01 | 2010-04-01 | Ronnie Jack Garmon | Methods and systems for customer performance scoring |
MD23Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare |
MD35Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare |
MD36Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare |
MD24Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare |
LT3912643T (lt) | 2009-02-13 | 2023-02-10 | Immunomedics Inc. | Imunokonjugatai su ląstelės viduje skaldoma jungtimi |
WO2010096486A1 (en) | 2009-02-17 | 2010-08-26 | Cornell Research Foundation, Inc. | Methods and kits for diagnosis of cancer and prediction of therapeutic value |
CN102714296A (zh) | 2009-05-19 | 2012-10-03 | Aic布莱博公司 | 复合集电器及形成其的方法 |
US8221753B2 (en) | 2009-09-30 | 2012-07-17 | Tracon Pharmaceuticals, Inc. | Endoglin antibodies |
CA2782333C (en) | 2009-12-02 | 2019-06-04 | Imaginab, Inc. | J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use |
WO2011068845A1 (en) | 2009-12-02 | 2011-06-09 | Immunomedics, Inc. | Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy |
EP2552959B1 (en) | 2010-03-26 | 2017-01-11 | Memorial Sloan-Kettering Cancer Center | Antibodies to muc16 and methods of use thereof |
JP5702944B2 (ja) * | 2010-03-31 | 2015-04-15 | 独立行政法人国立がん研究センター | バイオマーカー |
WO2011133555A2 (en) | 2010-04-20 | 2011-10-27 | The Research Foundation Of State University Of New York | Compositions and methods for inhibiting matrix metalloproteinase (mmp)-mediated cell migration |
JP6145404B2 (ja) * | 2010-05-07 | 2017-06-14 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | エクスビボでの細胞の検出のための診断的方法 |
WO2012075173A2 (en) | 2010-12-01 | 2012-06-07 | Board Of Regents The University Of Texas System | Compositions and method for deimmunization of proteins |
WO2012106368A2 (en) | 2011-01-31 | 2012-08-09 | The Regents Of The University Of California | Methods for inhibiting prostate cancer |
US8314566B2 (en) * | 2011-02-22 | 2012-11-20 | Quarkstar Llc | Solid state lamp using light emitting strips |
CA2831572C (en) | 2011-05-02 | 2019-11-26 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
US10800856B2 (en) | 2012-06-07 | 2020-10-13 | Ambrx, Inc. | Prostate-specific membrane antigen antibody drug conjugates |
WO2013188740A1 (en) | 2012-06-14 | 2013-12-19 | Ambrx, Inc. | Anti-psma antibodies conjugated to nuclear receptor ligand polypeptides |
CN104379169A (zh) | 2012-08-14 | 2015-02-25 | Ibc药品公司 | 用于治疗疾病的t-细胞重定向双特异性抗体 |
UA115789C2 (uk) | 2012-09-05 | 2017-12-26 | Трейкон Фармасутікалз, Інк. | Композиція антитіла до cd105 та її застосування |
EP2904012A4 (en) * | 2012-10-05 | 2016-05-04 | Univ Cornell | ANDROGEN SUPPRESSION, PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND CONCEPT FOR CONDITIONALLY REINFORCED VULNERABILITY |
AU2013328580B2 (en) | 2012-10-12 | 2016-01-21 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
SI2900277T1 (sl) | 2012-12-13 | 2022-05-31 | Immunomedics, Inc. | Odmerki imunokonjugatov protiteles in SN-38 za boljšo učinkovitost in zmanjšano toksičnost |
US11242399B2 (en) | 2013-02-19 | 2022-02-08 | Adienne S.A. | Anti-CD26 antibodies |
AU2014230735B2 (en) | 2013-03-13 | 2018-03-15 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
EP2968503B1 (en) | 2013-03-15 | 2018-08-15 | Intrinsic LifeSciences LLC | Anti-hepcidin antibodies and uses thereof |
JP6908964B2 (ja) | 2013-10-18 | 2021-07-28 | ピーエスエムエー ディベロップメント カンパニー,エルエルシー | Psmaリガンドコンジュゲートによる併用療法 |
US20150147339A1 (en) | 2013-11-15 | 2015-05-28 | Psma Development Company, Llc | Biomarkers for psma targeted therapy for prostate cancer |
ES2978993T3 (es) | 2014-02-21 | 2024-09-23 | Ibc Pharmaceuticals Inc | Terapia de enfermedades mediante la inducción de la respuesta inmunitaria a las células que expresan Trop-2 |
EP3110445A4 (en) | 2014-02-25 | 2017-09-27 | Immunomedics, Inc. | Humanized rfb4 anti-cd22 antibody |
LT3151865T (lt) | 2014-05-22 | 2021-10-25 | Byondis B.V. | Prijungiamų vaistų vietai specifinis konjugavimas su antikūnais ir to pasekoje gaunami avk |
US9580495B2 (en) | 2014-06-24 | 2017-02-28 | Immunomedics, Inc. | Anti-histone therapy for vascular necrosis in severe glomerulonephritis |
EP3193940A1 (en) | 2014-09-10 | 2017-07-26 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
CA2961917A1 (en) | 2014-09-22 | 2016-03-31 | Intrinsic Lifesciences Llc | Humanized anti-hepcidin antibodies and uses thereof |
EP3204018B1 (en) | 2014-10-07 | 2021-08-25 | Immunomedics, Inc. | Neoadjuvant use of antibody-drug conjugates |
US9926375B2 (en) | 2014-11-12 | 2018-03-27 | Tracon Pharmaceuticals, Inc. | Anti-endoglin antibodies and uses thereof |
AU2015346444A1 (en) | 2014-11-12 | 2017-05-04 | Tracon Pharmaceuticals, Inc. | Anti-endoglin antibodies and uses thereof |
CN104447955B (zh) * | 2014-11-23 | 2018-04-20 | 南京市第一医院 | 一种与psma膜外区靶向性结合的多肽及其应用 |
EP3064507A1 (en) | 2015-03-06 | 2016-09-07 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Fusion proteins comprising a binding protein and an interleukin-15 polypeptide having a reduced affinity for IL15ra and therapeutic uses thereof |
KR102618312B1 (ko) | 2015-03-17 | 2023-12-28 | 메모리얼 슬로안 케터링 캔서 센터 | 항muc16 항체 및 그의 용도 |
US10722523B2 (en) | 2015-03-17 | 2020-07-28 | The Regents Of The University Of California | Chemoimmunotherapy for epithelial cancer |
CN107428837A (zh) | 2015-04-22 | 2017-12-01 | 免疫医疗公司 | 循环trop‑2阳性癌细胞的分离、检测、诊断和/或鉴定 |
SG10202002131PA (en) | 2015-05-21 | 2020-05-28 | Harpoon Therapeutics Inc | Trispecific binding proteins and methods of use |
JP6980980B2 (ja) | 2015-06-25 | 2021-12-15 | イミューノメディクス、インコーポレイテッドImmunomedics, Inc. | 抗hla‐drまたは抗trop‐2抗体と微小管阻害剤、parp阻害剤、ブルトンキナーゼ阻害剤またはホスホイノシチド3‐キナーゼ阻害剤との併用は癌の治療効果を有意に改善する |
EP3316885B1 (en) | 2015-07-01 | 2021-06-23 | Immunomedics, Inc. | Antibody-sn-38 immunoconjugates with a cl2a linker |
JOP20160154B1 (ar) | 2015-07-31 | 2021-08-17 | Regeneron Pharma | أجسام ضادة مضاد لل psma، وجزيئات رابطة لمستضد ثنائي النوعية الذي يربط psma و cd3، واستخداماتها |
KR20180050321A (ko) | 2015-08-07 | 2018-05-14 | 이미지냅 인코포레이티드 | 분자를 표적화하기 위한 항원 결합 구조체 |
EP3192810A1 (en) * | 2016-01-14 | 2017-07-19 | Deutsches Krebsforschungszentrum | Psma binding antibody and uses thereof |
US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
IL263102B2 (en) | 2016-05-20 | 2023-11-01 | Harpoon Therapeutics Inc | A serum albumin-binding protein with a single site |
SG11201810331YA (en) | 2016-05-20 | 2018-12-28 | Harpoon Therapeutics Inc | Single chain variable fragment cd3 binding proteins |
EP4282434A3 (en) | 2016-06-06 | 2024-03-06 | Abzena (UK) Limited | Antibodies, uses thereof and conjugates thereof |
GB201614162D0 (en) | 2016-08-18 | 2016-10-05 | Polytherics Ltd | Antibodies, uses thereof and conjugates thereof |
CN109862919A (zh) | 2016-10-11 | 2019-06-07 | 免疫医疗有限公司 | 抗体-药物缀合物联合免疫介导的治疗剂 |
KR102275008B1 (ko) | 2016-11-23 | 2021-07-13 | 하푼 테라퓨틱스, 인크. | 전립선 특이 막 항원 결합 단백질 |
JP7215997B2 (ja) | 2016-11-23 | 2023-01-31 | ハープーン セラピューティクス,インク. | 前立腺特異的膜抗原(psma)を標的とする三重特異性タンパク質と使用方法 |
US11266745B2 (en) | 2017-02-08 | 2022-03-08 | Imaginab, Inc. | Extension sequences for diabodies |
US11535668B2 (en) | 2017-02-28 | 2022-12-27 | Harpoon Therapeutics, Inc. | Inducible monovalent antigen binding protein |
WO2018209298A1 (en) | 2017-05-12 | 2018-11-15 | Harpoon Therapeutics, Inc. | Mesothelin binding proteins |
CA3063362A1 (en) | 2017-05-12 | 2018-11-15 | Harpoon Therapeutics, Inc. | Msln targeting trispecific proteins and methods of use |
AU2018346955B2 (en) | 2017-10-13 | 2024-08-29 | Harpoon Therapeutics, Inc. | B cell maturation antigen binding proteins |
CN111630070B (zh) | 2017-10-13 | 2024-07-30 | 哈普恩治疗公司 | 三特异性蛋白质及使用方法 |
CN111511484A (zh) | 2017-11-04 | 2020-08-07 | 索纳纳米技术公司 | 金属纳米颗粒及制备所述金属纳米颗粒的方法 |
CN112119157A (zh) | 2018-03-06 | 2020-12-22 | 宾夕法尼亚大学董事会 | 前列腺特异性膜抗原car及其使用方法 |
DK3773910T3 (da) * | 2018-03-29 | 2024-08-19 | Ambrx Inc | Humaniseret anti-prostata-specifikt membranantigen(PSMA)-antistof-lægemiddelkonjugater |
EP3796942A1 (en) | 2018-05-23 | 2021-03-31 | ADC Therapeutics SA | Molecular adjuvant |
EP3587454A1 (en) * | 2018-06-27 | 2020-01-01 | Albert-Ludwigs-Universität Freiburg | Chimeric antigen receptors that bind to prostate specific membrane antigen |
CA3104800A1 (en) | 2018-07-31 | 2020-02-06 | Heidelberg Pharma Research Gmbh | Humanized antibodies against psma |
IL281683B2 (en) | 2018-09-25 | 2023-04-01 | Harpoon Therapeutics Inc | dll3 binding proteins and methods of use |
USD925928S1 (en) | 2019-03-01 | 2021-07-27 | Simplehuman, Llc | Vanity mirror |
US11180563B2 (en) | 2020-02-21 | 2021-11-23 | Harpoon Therapeutics, Inc. | FLT3 binding proteins and methods of use |
CN116390772A (zh) | 2020-07-07 | 2023-07-04 | 博泰康医药公司 | 新型美登素类似物作为adc有效载荷及其在癌症治疗中的用途 |
US20230372528A1 (en) | 2020-10-16 | 2023-11-23 | University Of Georgia Research Foundation, Inc. | Glycoconjugates |
CN112285082A (zh) * | 2020-10-28 | 2021-01-29 | 上海睿钰生物科技有限公司 | 一种基于细胞直径评价细胞杀伤效力的方法及其应用 |
GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
WO2022239720A1 (ja) | 2021-05-10 | 2022-11-17 | 公益財団法人川崎市産業振興財団 | 抗原への結合親和性を低減させた抗体 |
Family Cites Families (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4472509A (en) | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
US4454106A (en) | 1982-06-07 | 1984-06-12 | Gansow Otto A | Use of metal chelate conjugated monoclonal antibodies |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4824986A (en) | 1985-04-26 | 1989-04-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Metal chelate protein conjugate |
US4814275A (en) * | 1985-05-13 | 1989-03-21 | E.I. Dupont De Nemours And Company | Monoclonal hybridoma antibody specific for a human epithelial antigen |
US4735210A (en) | 1985-07-05 | 1988-04-05 | Immunomedics, Inc. | Lymphographic and organ imaging method and kit |
US5776093A (en) | 1985-07-05 | 1998-07-07 | Immunomedics, Inc. | Method for imaging and treating organs and tissues |
US5525338A (en) | 1992-08-21 | 1996-06-11 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin conjugates |
US4863854A (en) * | 1985-08-12 | 1989-09-05 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies to mucin-like human differentiation antigens |
JP2574269B2 (ja) * | 1985-12-17 | 1997-01-22 | イ−スタン・バ−ジニア・メデイカル・オ−ソリテイ | ヒト前立腺腫瘍関連抗原に対する結合特異性を有するモノクロ−ナル抗体類およびそれらを使用する方法 |
US4885363A (en) | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
MX174467B (es) | 1986-01-23 | 1994-05-17 | Squibb & Sons Inc | 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos |
DE3772785D1 (de) | 1986-01-23 | 1991-10-17 | Squibb & Sons Inc | 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga. |
AU593611B2 (en) | 1986-02-14 | 1990-02-15 | Nihon Medi-Physics Co., Ltd. | High molecular compounds having amino groups, and their utilization |
AU8152887A (en) | 1986-10-17 | 1988-05-06 | Cytogen Corporation | Method for preparation of protein-chelator-metal ion compositions suitable for injection |
US4863851A (en) * | 1986-10-20 | 1989-09-05 | The Upjohn Company | Monoclonal antibody to prostate secretory protein |
US5057302A (en) | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
CA1306739C (en) | 1987-02-16 | 1992-08-25 | Gohfu Suzukamo | Solid base, process for preparing the same and use of the same in preparation of internal olefins |
US5013645A (en) * | 1987-04-14 | 1991-05-07 | Abbott Laboratories | Immunological methods and materials for detection of tumor associated antigens |
US5531978A (en) | 1987-07-16 | 1996-07-02 | Nycomed Imaging As | Aminopolycarboxylic acids and derivatives thereof |
WO1989000557A1 (en) | 1987-07-16 | 1989-01-26 | Cockbain, Julian, Roderick, Michaelson | Aminopolycarboxylic acids and derivatives thereof |
GB9007965D0 (en) | 1990-04-09 | 1990-06-06 | Nycomed As | Compounds |
US5217704A (en) | 1987-11-06 | 1993-06-08 | Abbott Laboratories | Methods and materials for the preparation of metal labelled antibody solutions |
AU619218B2 (en) | 1987-11-06 | 1992-01-23 | Abbott Laboratories | Methods and materials for the preparation of metal labelled antibody solutions |
US5130118A (en) | 1987-11-06 | 1992-07-14 | Abbott Laboratories | Methods and materials for the preparation of metal labelled antibody solutions |
US5342924A (en) * | 1987-12-31 | 1994-08-30 | Tanox Biosystems, Inc. | Extracellular segments of human ε immunoglobulin anchoring peptides and antibodies specific therefor |
GB8801646D0 (en) | 1988-01-26 | 1988-02-24 | Nycomed As | Chemical compounds |
US5229289A (en) * | 1988-03-11 | 1993-07-20 | The Biomembrane Institute | Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human and with synthetic carbohydrate-carrier conjugates |
US5162504A (en) * | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
US5118611A (en) * | 1988-07-25 | 1992-06-02 | Adeza Biomedical Corporation | Adenocarcinoma antigen binding methods and reagents |
WO1990009379A1 (en) | 1989-02-10 | 1990-08-23 | Celltech Limited | Aza-macrocycles and processes for their preparation |
US5053503A (en) | 1989-02-17 | 1991-10-01 | Centocor | Chelating agents |
DE3911816A1 (de) | 1989-04-11 | 1990-10-25 | Hoechst Ag | Substituierte 1,4,7,10-tetraazacyclotridecane, verfahren zu deren herstellung sowie verwendung derselben zur markierung von substanzen mit radionukliden |
US5244816A (en) | 1989-10-11 | 1993-09-14 | Akzo N.V. | Method for purifying chelator conjugated compounds |
EP0453554A4 (en) | 1989-11-13 | 1993-02-17 | Xoma Corporation | Chimeric mouse human antibodies with specificity to hiv antigens |
GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
GB9115192D0 (en) | 1991-07-12 | 1991-08-28 | Antisoma Ltd | Cancer treatment |
US5227471A (en) * | 1992-01-30 | 1993-07-13 | Eastern Virginia Medical School Of The Medical College Of Hampton Roads | Monoclonal antibody PD41 that binds to a prostate mucin antigen that is expressed in human prostatic carcinoma |
DE69332948T2 (de) | 1992-03-05 | 2003-11-27 | Board Of Regents, The University Of Texas System | Verwendung von Immunokonjugate zur Diagnose und/oder Therapie der vaskularisierten Tumoren |
US5877289A (en) | 1992-03-05 | 1999-03-02 | The Scripps Research Institute | Tissue factor compositions and ligands for the specific coagulation of vasculature |
US6093399A (en) | 1992-03-05 | 2000-07-25 | Board Of Regents, The University Of Texas System | Methods and compositions for the specific coagulation of vasculature |
US6004555A (en) | 1992-03-05 | 1999-12-21 | Board Of Regents, The University Of Texas System | Methods for the specific coagulation of vasculature |
US5965132A (en) | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
US5660827A (en) | 1992-03-05 | 1997-08-26 | Board Of Regents, The University Of Texas System | Antibodies that bind to endoglin |
US6036955A (en) | 1992-03-05 | 2000-03-14 | The Scripps Research Institute | Kits and methods for the specific coagulation of vasculature |
US5489525A (en) * | 1992-10-08 | 1996-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibodies to prostate cells |
EP1757694A3 (en) * | 1992-11-05 | 2008-02-27 | Sloan Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
US5428156A (en) | 1993-04-02 | 1995-06-27 | Associated Universities, Inc. | Synthesis of macrocyclic polyaminocarboxylates and their use for preparing stable radiometal antibody immunoconjugates for therapy, spect and pet imaging |
CA2163107C (en) | 1993-05-17 | 2001-04-17 | David Milton Goldenberg | Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates |
US5935818A (en) | 1995-02-24 | 1999-08-10 | Sloan-Kettering Institute For Cancer Research | Isolated nucleic acid molecule encoding alternatively spliced prostate-specific membrane antigen and uses thereof |
US5599677A (en) * | 1993-12-29 | 1997-02-04 | Abbott Laboratories | Immunoassays for prostate specific antigen |
AU2194695A (en) | 1994-03-28 | 1995-10-17 | Regents Of The University Of California, The | Method for preparing radionuclide-labeled chelating agent-ligand complexes |
US6693190B1 (en) | 1994-05-11 | 2004-02-17 | Bracco International B.V. | Enhanced relaxivity monomeric and multimeric compounds |
US5541087A (en) | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
AU717937B2 (en) | 1995-02-24 | 2000-04-06 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
US5773292A (en) | 1995-06-05 | 1998-06-30 | Cornell University | Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood |
DE69638134D1 (de) | 1995-06-07 | 2010-04-08 | Immunomedics Inc | Verbesserte abgabe von diagnostischen und therapeutischen stoffen an einem zielort |
IT1283218B1 (it) | 1996-03-08 | 1998-04-16 | Bracco Spa | Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi |
ES2260788T3 (es) | 1996-03-25 | 2006-11-01 | Medarex, Inc. | Anticuerpos monoclonales especificos para el dominio estracelular de antigeno de membrana especifico de la prostata. |
US6150508A (en) | 1996-03-25 | 2000-11-21 | Northwest Biotherapeutics, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US6962981B1 (en) * | 1996-03-25 | 2005-11-08 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US6136311A (en) | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
US5804602A (en) | 1996-06-17 | 1998-09-08 | Guilford Pharmaceuticals Inc. | Methods of cancer treatment using naaladase inhibitors |
US5958474A (en) | 1996-08-21 | 1999-09-28 | Nestec S.A. | Process for preparing food flavor precursors |
IT1291623B1 (it) | 1997-04-18 | 1999-01-11 | Bracco Spa | Procedimento per la coniugazione di chelanti con molecole contenenti gruppi amminici |
AU3305699A (en) | 1998-02-26 | 1999-09-15 | Beckman Coulter, Inc. | Prostate-specific membrane antigens and methods of making and using |
WO2000050457A1 (en) | 1999-02-22 | 2000-08-31 | Beckman Coulter, Inc. | Prostate-specific membrane antigens and methods of making and using |
US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
JP2004510683A (ja) | 1999-06-07 | 2004-04-08 | センター・フォー・モレキュラー・メディシン・アンド・イムノロジー | 放射免疫療法において断片に付着されるα線エミッタまたはβ線エミッタ |
CA2422291C (en) | 2000-09-15 | 2011-03-08 | Sloan-Kettering Institute For Cancer Research | Targeted alpha particle therapy using actinium-225 conjugates |
JP4619651B2 (ja) | 2001-06-01 | 2011-01-26 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 前立腺特異的膜抗原に対する修飾抗体およびその使用 |
US7514078B2 (en) | 2001-06-01 | 2009-04-07 | Cornell Research Foundation, Inc. | Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies |
-
1997
- 1997-04-09 US US08/838,682 patent/US6107090A/en not_active Expired - Lifetime
- 1997-07-17 BR BR9710487A patent/BR9710487A/pt not_active Application Discontinuation
- 1997-07-17 IL IL12797997A patent/IL127979A0/xx not_active IP Right Cessation
- 1997-07-17 DE DE69735368T patent/DE69735368T2/de not_active Expired - Lifetime
- 1997-07-17 EP EP97934922A patent/EP0956506B1/en not_active Expired - Lifetime
- 1997-07-17 EA EA200400179A patent/EA200400179A1/ru unknown
- 1997-07-17 EP EP05021545A patent/EP1655605A3/en not_active Withdrawn
- 1997-07-17 JP JP50699598A patent/JP4503102B2/ja not_active Expired - Lifetime
- 1997-07-17 AU AU37976/97A patent/AU733544C/en not_active Expired
- 1997-07-17 EA EA199900033A patent/EA004634B1/ru not_active IP Right Cessation
- 1997-07-17 NZ NZ333683A patent/NZ333683A/en not_active IP Right Cessation
- 1997-07-17 AT AT97934922T patent/ATE319089T1/de active
- 1997-07-17 CN CNB2004100544223A patent/CN100344970C/zh not_active Expired - Lifetime
- 1997-07-17 WO PCT/US1997/012035 patent/WO1998003873A1/en active IP Right Grant
- 1997-07-17 PT PT97934922T patent/PT956506E/pt unknown
- 1997-07-17 CN CNB97197912XA patent/CN1165764C/zh not_active Expired - Lifetime
- 1997-07-17 CA CA002261018A patent/CA2261018C/en not_active Expired - Lifetime
- 1997-07-17 ES ES97934922T patent/ES2255723T3/es not_active Expired - Lifetime
- 1997-07-17 NZ NZ524036A patent/NZ524036A/xx not_active IP Right Cessation
-
1999
- 1999-07-20 US US09/357,704 patent/US7666425B1/en not_active Expired - Fee Related
- 1999-07-20 US US09/357,709 patent/US7112412B1/en not_active Expired - Fee Related
-
2000
- 2000-08-08 HK HK00104938A patent/HK1025631A1/xx not_active IP Right Cessation
-
2001
- 2001-08-13 US US09/929,665 patent/US20030003101A1/en not_active Abandoned
-
2004
- 2004-05-30 IL IL162230A patent/IL162230A/en not_active IP Right Cessation
-
2009
- 2009-04-06 JP JP2009092429A patent/JP5627191B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU733544C (en) | Treatment and diagnosis of cancer | |
IL126314A (en) | Monoclonal antibodies having an antigen binding region specific for the extracellular domain of prostate specific membrane antigen (psma) | |
JP5468587B2 (ja) | Cd44の表面発現を証明する細胞の細胞毒性媒介 | |
IL138497A0 (en) | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen | |
Johansson et al. | Comparison of fibronectin receptors from rat hepatocytes and fibroblasts. | |
AU9021898A (en) | Prostate tumor polynucleotide and antigen compositions | |
WO1999058570A3 (en) | Antibodies to the ed-b domain of fibronectin, conjugates containing them and use therefor for diagnosis and therapy of tumors and diseases associated with angiogenesis | |
NZ337413A (en) | Antibodies that bind to Prostate Stem Cell Antigen (PSCA) to treat prostate cancer. | |
WO2004065547A3 (en) | Pancreatic cancer associated antigen, antibody thereto, and diagnostic and treatment methods | |
Bruland et al. | Expression and characteristics of a novel human osteosarcoma-associated cell surface antigen | |
Heike et al. | Tissue distribution of the T cell activation antigen Ta1. Serological, immunohistochemical and biochemical investigations. | |
ATE350661T1 (de) | Diagnostischer und therapeutischer einsatz von antikörpern gegen den urokinase-rezeptor | |
Sofen et al. | Anti-squamous tumor antibodies in patients with squamous cell carcinoma | |
Ben-Aissa et al. | Specificities and binding properties of 2 monoclonal antibodies against carcinoma cells of the human urinary bladder | |
GIRARD et al. | Hyaluronectin: detection with monoclonal antibodies in human tumors | |
TR200103405T2 (tr) | İkiişlevli antikorlar ve bunların tümör-önleyici amilleri hedeflemede kullanımı. | |
WO1999043815A3 (en) | Human monoclonal antibodies capable of oligospecifically recognizing the major tumor-associated gangliosides and methods of use thereof | |
Masuko et al. | Efficient immunostaining of tissue sections with chemically modified monoclonal antibody | |
Wang et al. | Character of tumor associated protein recognized by monoclonal antibody against Yunnan gejiu lung cancer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |